LLPS-Art-2469
PMM
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Phosphomannomutase |
| Gene Name: | PMM, At2g45790, F4I18.23 |
| Ensembl Gene: | AT2G45790 |
| Ensembl Protein: | AT2G45790.1 |
| Organism: | Arabidopsis thaliana |
| Taxa ID: | 3702 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule, Others | Predicted from orthologs | (View) |
▼ FUNCTION
| Involved in ascorbic acid biosynthesis and in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | AT2G45790.1 | AT2G45790.1 |
| UniProt | O80840, PMM_ARATH, Q1W379 | |
| GeneBank | AY088930, AC004665, AY113964, CP002685, DQ442991, AY050806 | AAM45012.1, AEC10601.1, ABD97870.1, AAC28545.1, AAM67236.1, AAK92741.1 |
| RefSeq | NM_130142.4 | NP_182103.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAAKIPGVIA LFDVDGTLTA PRKEATPELL DFIRELRKVV TIGVVGGSDL SKISEQLGKT 60 61 VTNDYDYCFS ENGLVAHKDG KSIGIQSLKL HLGDDKLKEL INFTLHYIAD LDIPIKRGTF 120 121 IEFRNGMLNV SPIGRNCSQE ERDEFERYDK VQNIRPKMVA ELRERFAHLN LTFSIGGQIS 180 181 FDVFPKGWDK TYCLQYLEDF SEIHFFGDKT YEGGNDYEIY ESPKTIGHSV TSPDDTVAKC 240 241 KALFMS 246 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCGGCGA AAATTCCCGG AGTGATCGCT TTGTTCGACG TCGACGGTAC TCTCACAGCT 60 61 CCAAGGAAGG AAGCTACTCC AGAATTGCTC GATTTTATCC GAGAATTGCG AAAGGTCGTC 120 121 ACTATTGGAG TCGTCGGTGG ATCTGATCTA AGTAAGATAT CTGAGCAGCT TGGCAAAACA 180 181 GTCACAAACG ACTATGATTA TTGTTTCTCT GAGAATGGTC TTGTCGCCCA TAAAGATGGG 240 241 AAATCCATTG GAATTCAGAG CCTGAAGCTG CACCTTGGAG ACGATAAACT CAAGGAGTTG 300 301 ATAAATTTCA CGCTGCACTA CATTGCAGAC CTGGATATTC CAATTAAGAG GGGAACATTT 360 361 ATTGAATTCC GAAATGGAAT GCTCAATGTA TCACCCATTG GTCGCAACTG CAGCCAAGAA 420 421 GAAAGAGATG AATTTGAGAG ATATGATAAG GTTCAAAACA TCCGACCAAA GATGGTAGCT 480 481 GAACTTCGTG AGCGGTTTGC ACATCTTAAC CTTACTTTCT CAATTGGGGG ACAGATAAGC 540 541 TTCGATGTCT TCCCTAAAGG TTGGGATAAG ACTTACTGCT TGCAATACCT CGAGGACTTC 600 601 AGTGAAATCC ATTTCTTCGG TGACAAGACC TATGAGGGTG GAAATGACTA TGAAATCTAT 660 661 GAATCACCAA AAACAATTGG CCATTCAGTT ACGAGTCCAG ATGACACAGT GGCAAAATGC 720 721 AAGGCTCTGT TCATGTCTTG A 741 |
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytosol | |
Molecular Function | Phosphomannomutase activity | |
Biological Process | GDP-mannose biosynthetic process | |
Biological Process | L-ascorbic acid biosynthetic process | |
Biological Process | Mannose metabolic process | |
Biological Process | Protein N-linked glycosylation | |
Biological Process | Protein targeting to ER | |
Biological Process | Response to salt stress |
▼ ANNOTATION
| Disorder | ||||
| IUPred2A | ||||
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Function | ||||
| PIRSF | ||||
| Localization | ||||
| COMPARTMENTS | ||||
| Expression | ||||
| ArrayExpress | ||||
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Arl-1609 | Arabidopsis lyrata | 97.56 | 1e-178 | 498 |
| LLPS-Brn-1325 | Brassica napus | 91.43 | 2e-167 | 470 |
| LLPS-Brr-1355 | Brassica rapa | 90.61 | 2e-166 | 467 |
| LLPS-Bro-2824 | Brassica oleracea | 90.24 | 4e-166 | 466 |
| LLPS-Pot-2710 | Populus trichocarpa | 85.71 | 2e-148 | 422 |
| LLPS-Via-0283 | Vigna angularis | 84.51 | 1e-126 | 365 |
| LLPS-Phv-2322 | Phaseolus vulgaris | 83.27 | 3e-145 | 413 |
| LLPS-Thc-2312 | Theobroma cacao | 83.27 | 2e-145 | 414 |
| LLPS-Cus-0928 | Cucumis sativus | 83.27 | 4e-146 | 416 |
| LLPS-Gor-0236 | Gossypium raimondii | 82.93 | 2e-145 | 414 |
| LLPS-Glm-2176 | Glycine max | 82.45 | 6e-144 | 410 |
| LLPS-Mae-2506 | Manihot esculenta | 82.11 | 2e-145 | 414 |
| LLPS-Coc-2217 | Corchorus capsularis | 82.11 | 4e-144 | 410 |
| LLPS-Prp-0792 | Prunus persica | 82.11 | 1e-152 | 432 |
| LLPS-Lep-0066 | Leersia perrieri | 81.67 | 3e-146 | 423 |
| LLPS-Ors-1382 | Oryza sativa | 81.63 | 6e-151 | 428 |
| LLPS-Orr-0929 | Oryza rufipogon | 81.63 | 6e-151 | 428 |
| LLPS-Org-2136 | Oryza glaberrima | 81.63 | 6e-151 | 428 |
| LLPS-Orb-0231 | Oryza barthii | 81.63 | 5e-151 | 428 |
| LLPS-Orni-2222 | Oryza nivara | 81.63 | 6e-151 | 428 |
| LLPS-Orp-2386 | Oryza punctata | 81.48 | 3e-145 | 429 |
| LLPS-Nia-1746 | Nicotiana attenuata | 81.22 | 2e-149 | 424 |
| LLPS-Orm-1169 | Oryza meridionalis | 81.22 | 5e-150 | 426 |
| LLPS-Orgl-2193 | Oryza glumaepatula | 81.22 | 6e-150 | 426 |
| LLPS-Sot-1670 | Solanum tuberosum | 81.22 | 4e-150 | 426 |
| LLPS-Viv-0775 | Vitis vinifera | 80.89 | 2e-151 | 429 |
| LLPS-Orbr-1923 | Oryza brachyantha | 80.82 | 5e-149 | 423 |
| LLPS-Mua-0992 | Musa acuminata | 80.79 | 3e-76 | 234 |
| LLPS-Met-1268 | Medicago truncatula | 80.41 | 6e-148 | 420 |
| LLPS-Brd-1778 | Brachypodium distachyon | 80.24 | 8e-150 | 425 |
| LLPS-Hov-0713 | Hordeum vulgare | 80.0 | 4e-148 | 425 |
| LLPS-Amt-0104 | Amborella trichopoda | 79.18 | 6e-136 | 393 |
| LLPS-Sol-1925 | Solanum lycopersicum | 78.69 | 9e-142 | 405 |
| LLPS-Sob-2116 | Sorghum bicolor | 78.37 | 3e-147 | 419 |
| LLPS-Sei-1773 | Setaria italica | 78.37 | 4e-146 | 416 |
| LLPS-Ori-2268 | Oryza indica | 78.26 | 7e-146 | 416 |
| LLPS-Hea-2445 | Helianthus annuus | 77.96 | 2e-137 | 394 |
| LLPS-Dac-0894 | Daucus carota | 77.72 | 3e-115 | 336 |
| LLPS-Zem-1304 | Zea mays | 77.55 | 3e-146 | 416 |
| LLPS-Php-2472 | Physcomitrella patens | 76.76 | 9e-136 | 390 |
| LLPS-Sem-1232 | Selaginella moellendorffii | 76.03 | 1e-136 | 392 |
| LLPS-Tra-1951 | Triticum aestivum | 73.47 | 1e-140 | 402 |
| LLPS-Chr-0675 | Chlamydomonas reinhardtii | 72.8 | 3e-131 | 378 |
| LLPS-Tru-0138 | Triticum urartu | 71.32 | 2e-142 | 407 |
| LLPS-Osl-0614 | Ostreococcus lucimarinus | 71.12 | 5e-118 | 344 |
| LLPS-Chc-0769 | Chondrus crispus | 68.46 | 9e-120 | 349 |
| LLPS-Gas-0833 | Galdieria sulphuraria | 65.4 | 1e-111 | 328 |
| LLPS-Scj-0335 | Schizosaccharomyces japonicus | 63.01 | 4e-110 | 325 |
| LLPS-Abg-1126 | Absidia glauca | 62.83 | 3e-44 | 151 |
| LLPS-Put-0420 | Puccinia triticina | 62.71 | 2e-102 | 305 |
| LLPS-Scp-0397 | Schizosaccharomyces pombe | 62.6 | 1e-109 | 323 |
| LLPS-Xet-3776 | Xenopus tropicalis | 62.4 | 3e-102 | 304 |
| LLPS-Aon-3742 | Aotus nancymaae | 61.79 | 2e-104 | 310 |
| LLPS-Dio-2476 | Dipodomys ordii | 61.79 | 2e-104 | 310 |
| LLPS-Cogr-1486 | Colletotrichum graminicola | 61.45 | 2e-103 | 308 |
| LLPS-Tum-1074 | Tuber melanosporum | 61.38 | 9e-104 | 309 |
| LLPS-Pug-1062 | Puccinia graminis | 61.32 | 1e-102 | 305 |
| LLPS-Mel-0073 | Melampsora laricipopulina | 61.16 | 5e-103 | 306 |
| LLPS-Otg-4430 | Otolemur garnettii | 61.13 | 2e-101 | 302 |
| LLPS-Orc-3038 | Oryctolagus cuniculus | 61.13 | 5e-102 | 304 |
| LLPS-Fia-0727 | Ficedula albicollis | 61.11 | 5e-88 | 267 |
| LLPS-Hos-4391 | Homo sapiens | 60.98 | 8e-103 | 305 |
| LLPS-Pat-4559 | Pan troglodytes | 60.98 | 6e-103 | 306 |
| LLPS-Man-2536 | Macaca nemestrina | 60.98 | 5e-103 | 306 |
| LLPS-Rhb-2784 | Rhinopithecus bieti | 60.98 | 4e-103 | 306 |
| LLPS-Mam-2662 | Macaca mulatta | 60.98 | 5e-103 | 306 |
| LLPS-Nol-3370 | Nomascus leucogenys | 60.98 | 5e-103 | 306 |
| LLPS-Chs-0461 | Chlorocebus sabaeus | 60.98 | 5e-103 | 306 |
| LLPS-Maf-3020 | Macaca fascicularis | 60.98 | 3e-103 | 306 |
| LLPS-Cea-2427 | Cercocebus atys | 60.98 | 5e-103 | 306 |
| LLPS-Gog-0970 | Gorilla gorilla | 60.98 | 4e-103 | 306 |
| LLPS-Caj-3877 | Callithrix jacchus | 60.98 | 2e-103 | 307 |
| LLPS-Paa-4064 | Papio anubis | 60.98 | 5e-103 | 306 |
| LLPS-Eqc-1465 | Equus caballus | 60.92 | 2e-99 | 299 |
| LLPS-Lac-2489 | Latimeria chalumnae | 60.83 | 4e-96 | 289 |
| LLPS-Pes-1966 | Pelodiscus sinensis | 60.81 | 4e-83 | 254 |
| LLPS-Gaga-1499 | Gallus gallus | 60.73 | 3e-101 | 301 |
| LLPS-Asm-0601 | Astyanax mexicanus | 60.58 | 1e-100 | 300 |
| LLPS-Pap-3166 | Pan paniscus | 60.57 | 4e-102 | 304 |
| LLPS-Scc-1595 | Schizosaccharomyces cryophilus | 60.57 | 7e-109 | 322 |
| LLPS-Mea-1391 | Mesocricetus auratus | 60.42 | 1e-100 | 300 |
| LLPS-Icp-3469 | Ictalurus punctatus | 60.42 | 9e-100 | 298 |
| LLPS-Tag-1558 | Taeniopygia guttata | 60.41 | 3e-100 | 299 |
| LLPS-Anp-0165 | Anas platyrhynchos | 60.27 | 2e-88 | 268 |
| LLPS-Cap-2344 | Cavia porcellus | 60.16 | 3e-102 | 304 |
| LLPS-Ict-3072 | Ictidomys tridecemlineatus | 60.16 | 1e-101 | 303 |
| LLPS-Trr-1259 | Trichoderma reesei | 60.0 | 1e-104 | 311 |
| LLPS-Fuo-1336 | Fusarium oxysporum | 60.0 | 2e-102 | 306 |
| LLPS-Trv-0095 | Trichoderma virens | 60.0 | 4e-102 | 305 |
| LLPS-Fuv-0073 | Fusarium verticillioides | 60.0 | 2e-102 | 305 |
| LLPS-Map-1140 | Magnaporthe poae | 59.84 | 2e-101 | 303 |
| LLPS-Urm-3732 | Ursus maritimus | 59.83 | 1e-99 | 298 |
| LLPS-Scf-2592 | Scleropages formosus | 59.83 | 5e-100 | 298 |
| LLPS-Vir-1480 | Vigna radiata | 59.79 | 8e-102 | 304 |
| LLPS-Sus-4652 | Sus scrofa | 59.76 | 3e-100 | 299 |
| LLPS-Mup-2594 | Mustela putorius furo | 59.76 | 1e-100 | 300 |
| LLPS-Loa-2550 | Loxodonta africana | 59.75 | 1e-99 | 297 |
| LLPS-Kop-0143 | Komagataella pastoris | 59.75 | 8e-104 | 308 |
| LLPS-Mum-3303 | Mus musculus | 59.58 | 2e-99 | 297 |
| LLPS-Ran-1769 | Rattus norvegicus | 59.58 | 5e-99 | 296 |
| LLPS-Sah-3779 | Sarcophilus harrisii | 59.51 | 1e-100 | 300 |
| LLPS-Fec-3257 | Felis catus | 59.35 | 8e-100 | 298 |
| LLPS-Fud-2608 | Fukomys damarensis | 59.35 | 2e-101 | 302 |
| LLPS-Gaa-3428 | Gasterosteus aculeatus | 59.32 | 6e-101 | 301 |
| LLPS-Myl-4475 | Myotis lucifugus | 59.27 | 5e-97 | 291 |
| LLPS-Fus-0853 | Fusarium solani | 59.2 | 4e-102 | 305 |
| LLPS-Orn-3130 | Oreochromis niloticus | 59.17 | 2e-100 | 300 |
| LLPS-Yal-1019 | Yarrowia lipolytica | 59.17 | 2e-98 | 295 |
| LLPS-Mod-0366 | Monodelphis domestica | 59.11 | 8e-99 | 296 |
| LLPS-Gag-1551 | Gaeumannomyces graminis | 59.04 | 4e-101 | 302 |
| LLPS-Orl-1009 | Oryzias latipes | 59.0 | 4e-100 | 299 |
| LLPS-Caf-4393 | Canis familiaris | 58.94 | 3e-99 | 297 |
| LLPS-Sac-0556 | Saccharomyces cerevisiae | 58.92 | 3e-94 | 284 |
| LLPS-Ved-0529 | Verticillium dahliae | 58.89 | 4e-103 | 308 |
| LLPS-Aim-3481 | Ailuropoda melanoleuca | 58.85 | 6e-98 | 293 |
| LLPS-Dar-3836 | Danio rerio | 58.75 | 8e-97 | 290 |
| LLPS-Mao-0824 | Magnaporthe oryzae | 58.63 | 3e-100 | 300 |
| LLPS-Beb-0801 | Beauveria bassiana | 58.4 | 1e-99 | 298 |
| LLPS-Miv-0792 | Microbotryum violaceum | 58.33 | 3e-69 | 220 |
| LLPS-Blg-1274 | Blumeria graminis | 58.33 | 3e-102 | 305 |
| LLPS-Bot-2171 | Bos taurus | 58.13 | 5e-97 | 291 |
| LLPS-Ova-3595 | Ovis aries | 58.13 | 3e-97 | 291 |
| LLPS-Pof-2953 | Poecilia formosa | 58.09 | 3e-98 | 294 |
| LLPS-Meg-1448 | Meleagris gallopavo | 58.04 | 1e-85 | 261 |
| LLPS-Cii-1967 | Ciona intestinalis | 58.02 | 7e-98 | 293 |
| LLPS-Cis-1921 | Ciona savignyi | 58.0 | 7e-102 | 303 |
| LLPS-Tar-0239 | Takifugu rubripes | 57.44 | 5e-102 | 304 |
| LLPS-Leo-1469 | Lepisosteus oculatus | 57.37 | 1e-98 | 295 |
| LLPS-Tut-1974 | Tursiops truncatus | 57.32 | 1e-96 | 290 |
| LLPS-Anc-2624 | Anolis carolinensis | 57.31 | 1e-98 | 296 |
| LLPS-Asg-1167 | Ashbya gossypii | 57.26 | 5e-98 | 293 |
| LLPS-Nec-0520 | Neurospora crassa | 57.2 | 1e-105 | 314 |
| LLPS-Zyt-1513 | Zymoseptoria tritici | 57.14 | 2e-97 | 293 |
| LLPS-Lem-1146 | Leptosphaeria maculans | 56.8 | 2e-95 | 288 |
| LLPS-Drm-2311 | Drosophila melanogaster | 56.67 | 1e-94 | 285 |
| LLPS-Asni-1324 | Aspergillus niger | 56.57 | 2e-96 | 290 |
| LLPS-Crn-1449 | Cryptococcus neoformans | 56.5 | 3e-98 | 295 |
| LLPS-Coo-1602 | Colletotrichum orbiculare | 56.35 | 2e-96 | 290 |
| LLPS-Cas-0723 | Carlito syrichta | 56.2 | 3e-91 | 277 |
| LLPS-Mal-3908 | Mandrillus leucophaeus | 56.2 | 3e-91 | 277 |
| LLPS-Poa-2887 | Pongo abelii | 55.79 | 1e-90 | 275 |
| LLPS-Nef-1289 | Neosartorya fischeri | 55.78 | 8e-94 | 283 |
| LLPS-Pytr-0726 | Pyrenophora triticirepentis | 55.78 | 2e-95 | 288 |
| LLPS-Pyt-1481 | Pyrenophora teres | 55.78 | 2e-95 | 288 |
| LLPS-Asn-1633 | Aspergillus nidulans | 55.56 | 7e-95 | 286 |
| LLPS-Cae-0546 | Caenorhabditis elegans | 55.56 | 9e-90 | 273 |
| LLPS-Cym-0317 | Cyanidioschyzon merolae | 55.46 | 3e-92 | 279 |
| LLPS-Dos-1611 | Dothistroma septosporum | 55.16 | 7e-99 | 296 |
| LLPS-Ten-2084 | Tetraodon nigroviridis | 54.79 | 6e-22 | 91.7 |
| LLPS-Asc-1365 | Aspergillus clavatus | 54.58 | 4e-92 | 279 |
| LLPS-Usm-0838 | Ustilago maydis | 54.23 | 3e-93 | 282 |
| LLPS-Ast-0171 | Aspergillus terreus | 54.08 | 1e-87 | 266 |
| LLPS-Spr-1274 | Sporisorium reilianum | 54.05 | 1e-92 | 280 |
| LLPS-Ere-0494 | Erinaceus europaeus | 53.85 | 6e-84 | 258 |
| LLPS-Scs-0639 | Sclerotinia sclerotiorum | 53.8 | 2e-56 | 185 |
| LLPS-Scm-1068 | Scophthalmus maximus | 53.31 | 8e-87 | 265 |
| LLPS-Ora-1651 | Ornithorhynchus anatinus | 52.92 | 2e-85 | 261 |
| LLPS-Aso-1531 | Aspergillus oryzae | 52.06 | 7e-92 | 278 |
| LLPS-Asf-1285 | Aspergillus flavus | 52.06 | 7e-92 | 278 |
| LLPS-Asfu-0786 | Aspergillus fumigatus | 51.79 | 4e-79 | 245 |
| LLPS-Cog-0919 | Colletotrichum gloeosporioides | 49.37 | 6e-67 | 213 |
| LLPS-Xim-2624 | Xiphophorus maculatus | 47.6 | 9e-80 | 249 |
| LLPS-Phn-0938 | Phaeosphaeria nodorum | 43.14 | 3e-19 | 87.8 |