LLPS-Cap-2344
PMM2
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Phosphomannomutase |
| Gene Name: | PMM2 |
| Ensembl Gene: | ENSCPOG00000038289.1 |
| Ensembl Protein: | ENSCPOP00000032898.1 |
| Organism: | Cavia porcellus |
| Taxa ID: | 10141 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule, Others | Predicted from orthologs | (View) |
▼ FUNCTION
| Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSCPOT00000033875.1 | ENSCPOP00000032898.1 |
| UniProt | A0A286Y5U0, A0A286Y5U0_CAVPO | |
| GeneBank | AAKN02007473 | |
| RefSeq | XM_003477744.3 | XP_003477792.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MATTRPVLCL FDVDGTLTAP RQKITKEMDD FLQKLKQKIK IGVVGGSDLE KVQEQLGNDV 60 61 VQKYNYVFPE NGLVAFKDGK LLCKQSIQGH LGEALIQDLI NYCLSYIAKI KLPKKRGTFI 120 121 EFRNGMLNVS PVGRSCSQEE RIEFYELDKK ENIRQKFVAD LQKEFAGKGL TFSIGGQISF 180 181 DVFPDGWDKR YCLRHVENDG YKTIYFFGDK TMPGGNDYEI FTDPRTVGYT VTAPEDTRRI 240 241 CEELFA 246 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCTACGA CCCGCCCAGT GCTGTGCCTC TTTGATGTGG ATGGGACCCT GACGGCCCCG 60 61 CGGCAGAAAA TTACCAAAGA AATGGATGAC TTTCTACAAA AATTGAAGCA GAAGATCAAA 120 121 ATTGGAGTGG TAGGCGGCTC AGACTTGGAG AAAGTACAGG AACAACTGGG AAATGATGTG 180 181 GTGCAGAAAT ATAACTATGT GTTTCCAGAA AATGGCTTGG TAGCATTTAA GGATGGGAAA 240 241 CTCTTATGTA AACAGAGTAT TCAAGGTCAC CTGGGTGAGG CCCTAATTCA AGATTTAATC 300 301 AACTACTGTC TAAGCTACAT TGCAAAAATT AAACTCCCGA AGAAAAGGGG CACTTTCATT 360 361 GAGTTCCGAA ATGGGATGCT GAATGTGTCC CCTGTTGGAC GAAGCTGCAG CCAAGAGGAA 420 421 CGCATTGAGT TCTACGAACT TGATAAAAAA GAAAACATAA GACAAAAATT CGTAGCAGAT 480 481 CTGCAGAAGG AATTTGCAGG GAAAGGCCTC ACATTTTCCA TAGGAGGCCA GATCAGCTTT 540 541 GATGTCTTTC CTGATGGATG GGACAAGAGA TACTGCCTGC GACATGTGGA AAATGACGGT 600 601 TACAAGACCA TTTACTTCTT TGGAGACAAA ACTATGCCAG GTGGCAATGA CTATGAGATC 660 661 TTCACAGATC CTCGAACTGT GGGCTACACC GTGACAGCAC CCGAGGACAC ACGCAGGATT 720 721 TGTGAAGAGC TCTTCGCTTA A 741 |
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytosol | |
Cellular Component | Neuronal cell body | |
Cellular Component | Nucleus | |
Molecular Function | Phosphomannomutase activity | |
Biological Process | GDP-mannose biosynthetic process |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Fud-2608 | Fukomys damarensis | 94.72 | 1e-172 | 483 |
| LLPS-Ict-3072 | Ictidomys tridecemlineatus | 93.9 | 3e-173 | 484 |
| LLPS-Chs-0461 | Chlorocebus sabaeus | 93.5 | 8e-172 | 481 |
| LLPS-Cea-2427 | Cercocebus atys | 93.5 | 8e-172 | 481 |
| LLPS-Paa-4064 | Papio anubis | 93.5 | 8e-172 | 481 |
| LLPS-Mea-1391 | Mesocricetus auratus | 93.33 | 6e-168 | 471 |
| LLPS-Maf-3020 | Macaca fascicularis | 93.09 | 8e-172 | 481 |
| LLPS-Gog-0970 | Gorilla gorilla | 93.09 | 1e-170 | 478 |
| LLPS-Man-2536 | Macaca nemestrina | 93.09 | 2e-171 | 480 |
| LLPS-Orc-3038 | Oryctolagus cuniculus | 93.09 | 1e-168 | 473 |
| LLPS-Mam-2662 | Macaca mulatta | 93.09 | 2e-171 | 480 |
| LLPS-Pat-4559 | Pan troglodytes | 92.68 | 3e-170 | 477 |
| LLPS-Rhb-2784 | Rhinopithecus bieti | 92.68 | 3e-170 | 477 |
| LLPS-Nol-3370 | Nomascus leucogenys | 92.68 | 5e-170 | 476 |
| LLPS-Eqc-1465 | Equus caballus | 92.5 | 5e-164 | 464 |
| LLPS-Pap-3166 | Pan paniscus | 92.28 | 1e-169 | 475 |
| LLPS-Hos-4391 | Homo sapiens | 92.28 | 1e-169 | 475 |
| LLPS-Caj-3877 | Callithrix jacchus | 92.24 | 4e-169 | 474 |
| LLPS-Otg-4430 | Otolemur garnettii | 92.24 | 3e-167 | 469 |
| LLPS-Aon-3742 | Aotus nancymaae | 91.84 | 1e-169 | 475 |
| LLPS-Mup-2594 | Mustela putorius furo | 91.84 | 6e-168 | 471 |
| LLPS-Loa-2550 | Loxodonta africana | 91.77 | 3e-165 | 464 |
| LLPS-Urm-3732 | Ursus maritimus | 91.46 | 1e-167 | 470 |
| LLPS-Dio-2476 | Dipodomys ordii | 91.43 | 1e-167 | 470 |
| LLPS-Caf-4393 | Canis familiaris | 91.06 | 8e-168 | 471 |
| LLPS-Ran-1769 | Rattus norvegicus | 91.02 | 8e-164 | 460 |
| LLPS-Ova-3595 | Ovis aries | 90.61 | 9e-165 | 463 |
| LLPS-Aim-3481 | Ailuropoda melanoleuca | 90.36 | 1e-165 | 465 |
| LLPS-Myl-4475 | Myotis lucifugus | 90.32 | 2e-164 | 462 |
| LLPS-Bot-2171 | Bos taurus | 90.24 | 2e-164 | 462 |
| LLPS-Tut-1974 | Tursiops truncatus | 89.84 | 4e-164 | 461 |
| LLPS-Fec-3257 | Felis catus | 89.84 | 1e-165 | 465 |
| LLPS-Sus-4652 | Sus scrofa | 89.02 | 1e-161 | 455 |
| LLPS-Mum-3303 | Mus musculus | 88.57 | 3e-159 | 449 |
| LLPS-Sah-3779 | Sarcophilus harrisii | 87.76 | 8e-161 | 453 |
| LLPS-Mod-0366 | Monodelphis domestica | 86.53 | 3e-158 | 447 |
| LLPS-Pes-1966 | Pelodiscus sinensis | 83.86 | 1e-131 | 378 |
| LLPS-Gaga-1499 | Gallus gallus | 83.4 | 3e-151 | 429 |
| LLPS-Fia-0727 | Ficedula albicollis | 82.11 | 1e-133 | 383 |
| LLPS-Anp-0165 | Anas platyrhynchos | 81.78 | 5e-136 | 390 |
| LLPS-Ora-1651 | Ornithorhynchus anatinus | 81.59 | 3e-141 | 403 |
| LLPS-Tag-1558 | Taeniopygia guttata | 81.22 | 1e-147 | 420 |
| LLPS-Lac-2489 | Latimeria chalumnae | 75.82 | 7e-133 | 382 |
| LLPS-Orl-1009 | Oryzias latipes | 75.31 | 1e-135 | 389 |
| LLPS-Xet-3776 | Xenopus tropicalis | 75.0 | 8e-137 | 392 |
| LLPS-Leo-1469 | Lepisosteus oculatus | 74.59 | 5e-136 | 390 |
| LLPS-Scf-2592 | Scleropages formosus | 74.06 | 1e-132 | 382 |
| LLPS-Asm-0601 | Astyanax mexicanus | 73.66 | 3e-134 | 385 |
| LLPS-Icp-3469 | Ictalurus punctatus | 73.64 | 5e-131 | 377 |
| LLPS-Orn-3130 | Oreochromis niloticus | 73.22 | 7e-133 | 382 |
| LLPS-Dar-3836 | Danio rerio | 72.38 | 4e-130 | 375 |
| LLPS-Pof-2953 | Poecilia formosa | 70.29 | 3e-129 | 373 |
| LLPS-Tar-0239 | Takifugu rubripes | 69.87 | 3e-127 | 368 |
| LLPS-Gaa-3428 | Gasterosteus aculeatus | 69.75 | 7e-126 | 365 |
| LLPS-Cii-1967 | Ciona intestinalis | 68.6 | 6e-124 | 359 |
| LLPS-Cis-1921 | Ciona savignyi | 68.18 | 9e-122 | 354 |
| LLPS-Mal-3908 | Mandrillus leucophaeus | 67.22 | 2e-119 | 348 |
| LLPS-Poa-2887 | Pongo abelii | 67.22 | 7e-119 | 347 |
| LLPS-Cas-0723 | Carlito syrichta | 67.22 | 2e-119 | 348 |
| LLPS-Scm-1068 | Scophthalmus maximus | 66.4 | 1e-120 | 352 |
| LLPS-Meg-1448 | Meleagris gallopavo | 65.93 | 4e-106 | 313 |
| LLPS-Anc-2624 | Anolis carolinensis | 65.08 | 9e-120 | 349 |
| LLPS-Ere-0494 | Erinaceus europaeus | 63.49 | 6e-109 | 322 |
| LLPS-Ten-2084 | Tetraodon nigroviridis | 63.38 | 4e-27 | 105 |
| LLPS-Sei-1773 | Setaria italica | 61.09 | 7e-102 | 303 |
| LLPS-Sob-2116 | Sorghum bicolor | 61.09 | 6e-103 | 306 |
| LLPS-Amt-0104 | Amborella trichopoda | 61.09 | 2e-97 | 295 |
| LLPS-Mae-2506 | Manihot esculenta | 60.98 | 1e-96 | 290 |
| LLPS-Lep-0066 | Leersia perrieri | 60.67 | 3e-99 | 303 |
| LLPS-Nia-1746 | Nicotiana attenuata | 60.67 | 8e-100 | 298 |
| LLPS-Zem-1304 | Zea mays | 60.67 | 1e-102 | 305 |
| LLPS-Php-2472 | Physcomitrella patens | 60.41 | 3e-103 | 307 |
| LLPS-Osl-0614 | Ostreococcus lucimarinus | 60.34 | 9e-102 | 303 |
| LLPS-Sot-1670 | Solanum tuberosum | 60.25 | 2e-100 | 300 |
| LLPS-Brd-1778 | Brachypodium distachyon | 60.25 | 1e-101 | 303 |
| LLPS-Hov-0713 | Hordeum vulgare | 60.25 | 1e-101 | 306 |
| LLPS-Viv-0775 | Vitis vinifera | 60.25 | 7e-100 | 298 |
| LLPS-Met-1268 | Medicago truncatula | 60.16 | 1e-101 | 303 |
| LLPS-Arl-1609 | Arabidopsis lyrata | 60.16 | 7e-103 | 306 |
| LLPS-Art-2469 | Arabidopsis thaliana | 60.16 | 3e-102 | 304 |
| LLPS-Xim-2624 | Xiphophorus maculatus | 59.85 | 1e-113 | 336 |
| LLPS-Orb-0231 | Oryza barthii | 59.83 | 7e-100 | 298 |
| LLPS-Orni-2222 | Oryza nivara | 59.83 | 7e-100 | 298 |
| LLPS-Ors-1382 | Oryza sativa | 59.83 | 7e-100 | 298 |
| LLPS-Orm-1169 | Oryza meridionalis | 59.83 | 3e-100 | 299 |
| LLPS-Orr-0929 | Oryza rufipogon | 59.83 | 7e-100 | 298 |
| LLPS-Org-2136 | Oryza glaberrima | 59.83 | 7e-100 | 298 |
| LLPS-Via-0283 | Vigna angularis | 59.81 | 1e-82 | 253 |
| LLPS-Glm-2176 | Glycine max | 59.76 | 5e-97 | 291 |
| LLPS-Brn-1325 | Brassica napus | 59.76 | 7e-101 | 301 |
| LLPS-Cus-0928 | Cucumis sativus | 59.76 | 3e-97 | 291 |
| LLPS-Gor-0236 | Gossypium raimondii | 59.76 | 2e-95 | 287 |
| LLPS-Phv-2322 | Phaseolus vulgaris | 59.76 | 5e-96 | 288 |
| LLPS-Coc-2217 | Corchorus capsularis | 59.76 | 7e-96 | 288 |
| LLPS-Bro-2824 | Brassica oleracea | 59.76 | 1e-100 | 300 |
| LLPS-Pot-2710 | Populus trichocarpa | 59.74 | 7e-95 | 286 |
| LLPS-Scj-0335 | Schizosaccharomyces japonicus | 59.67 | 9e-97 | 291 |
| LLPS-Scc-1595 | Schizosaccharomyces cryophilus | 59.5 | 2e-99 | 298 |
| LLPS-Orgl-2193 | Oryza glumaepatula | 59.41 | 6e-99 | 296 |
| LLPS-Sac-0556 | Saccharomyces cerevisiae | 59.41 | 2e-95 | 287 |
| LLPS-Orp-2386 | Oryza punctata | 59.41 | 1e-95 | 301 |
| LLPS-Thc-2312 | Theobroma cacao | 59.35 | 6e-95 | 286 |
| LLPS-Prp-0792 | Prunus persica | 59.35 | 4e-101 | 301 |
| LLPS-Abg-1126 | Absidia glauca | 59.29 | 1e-41 | 144 |
| LLPS-Chr-0675 | Chlamydomonas reinhardtii | 59.26 | 8e-102 | 303 |
| LLPS-Sol-1925 | Solanum lycopersicum | 59.0 | 3e-97 | 291 |
| LLPS-Orbr-1923 | Oryza brachyantha | 58.87 | 2e-100 | 300 |
| LLPS-Brr-1355 | Brassica rapa | 58.78 | 1e-98 | 295 |
| LLPS-Sem-1232 | Selaginella moellendorffii | 58.58 | 2e-95 | 287 |
| LLPS-Chc-0769 | Chondrus crispus | 58.58 | 9e-96 | 288 |
| LLPS-Hea-2445 | Helianthus annuus | 58.54 | 3e-93 | 281 |
| LLPS-Ast-0171 | Aspergillus terreus | 57.51 | 4e-87 | 265 |
| LLPS-Ori-2268 | Oryza indica | 57.49 | 2e-95 | 287 |
| LLPS-Dac-0894 | Daucus carota | 57.14 | 3e-81 | 249 |
| LLPS-Mel-0073 | Melampsora laricipopulina | 57.03 | 2e-94 | 285 |
| LLPS-Scp-0397 | Schizosaccharomyces pombe | 57.02 | 2e-93 | 282 |
| LLPS-Nef-1289 | Neosartorya fischeri | 56.92 | 4e-94 | 284 |
| LLPS-Yal-1019 | Yarrowia lipolytica | 56.85 | 1e-95 | 288 |
| LLPS-Gag-1551 | Gaeumannomyces graminis | 56.69 | 5e-95 | 286 |
| LLPS-Asn-1633 | Aspergillus nidulans | 56.69 | 9e-92 | 278 |
| LLPS-Mua-0992 | Musa acuminata | 56.67 | 1e-48 | 164 |
| LLPS-Asni-1324 | Aspergillus niger | 56.52 | 2e-92 | 280 |
| LLPS-Asg-1167 | Ashbya gossypii | 56.2 | 2e-93 | 282 |
| LLPS-Put-0420 | Puccinia triticina | 56.2 | 1e-90 | 275 |
| LLPS-Aso-1531 | Aspergillus oryzae | 56.13 | 9e-95 | 286 |
| LLPS-Asf-1285 | Aspergillus flavus | 56.13 | 9e-95 | 286 |
| LLPS-Fuv-0073 | Fusarium verticillioides | 56.08 | 1e-91 | 278 |
| LLPS-Trr-1259 | Trichoderma reesei | 56.08 | 2e-94 | 285 |
| LLPS-Fuo-1336 | Fusarium oxysporum | 56.08 | 1e-91 | 278 |
| LLPS-Trv-0095 | Trichoderma virens | 56.08 | 6e-92 | 279 |
| LLPS-Tra-1951 | Triticum aestivum | 56.05 | 1e-98 | 295 |
| LLPS-Tum-1074 | Tuber melanosporum | 56.0 | 1e-91 | 278 |
| LLPS-Gas-0833 | Galdieria sulphuraria | 55.92 | 3e-93 | 281 |
| LLPS-Map-1140 | Magnaporthe poae | 55.91 | 6e-93 | 281 |
| LLPS-Usm-0838 | Ustilago maydis | 55.86 | 5e-92 | 279 |
| LLPS-Kop-0143 | Komagataella pastoris | 55.83 | 4e-95 | 286 |
| LLPS-Pug-1062 | Puccinia graminis | 55.78 | 4e-94 | 284 |
| LLPS-Spr-1274 | Sporisorium reilianum | 55.29 | 2e-91 | 278 |
| LLPS-Drm-2311 | Drosophila melanogaster | 54.96 | 4e-93 | 281 |
| LLPS-Fus-0853 | Fusarium solani | 54.9 | 2e-89 | 273 |
| LLPS-Crn-1449 | Cryptococcus neoformans | 54.58 | 2e-92 | 280 |
| LLPS-Asc-1365 | Aspergillus clavatus | 54.55 | 1e-89 | 273 |
| LLPS-Cae-0546 | Caenorhabditis elegans | 54.44 | 2e-92 | 279 |
| LLPS-Beb-0801 | Beauveria bassiana | 53.91 | 3e-89 | 272 |
| LLPS-Coo-1602 | Colletotrichum orbiculare | 53.61 | 4e-88 | 269 |
| LLPS-Mao-0824 | Magnaporthe oryzae | 53.54 | 4e-90 | 274 |
| LLPS-Tru-0138 | Triticum urartu | 53.45 | 2e-96 | 291 |
| LLPS-Blg-1274 | Blumeria graminis | 53.41 | 1e-86 | 265 |
| LLPS-Cogr-1486 | Colletotrichum graminicola | 53.39 | 1e-89 | 273 |
| LLPS-Asfu-0786 | Aspergillus fumigatus | 53.36 | 7e-82 | 252 |
| LLPS-Nec-0520 | Neurospora crassa | 53.33 | 1e-88 | 270 |
| LLPS-Ved-0529 | Verticillium dahliae | 52.94 | 6e-88 | 269 |
| LLPS-Zyt-1513 | Zymoseptoria tritici | 52.76 | 7e-87 | 266 |
| LLPS-Dos-1611 | Dothistroma septosporum | 51.97 | 5e-86 | 264 |
| LLPS-Pyt-1481 | Pyrenophora teres | 51.79 | 2e-82 | 254 |
| LLPS-Pytr-0726 | Pyrenophora triticirepentis | 51.79 | 4e-82 | 254 |
| LLPS-Lem-1146 | Leptosphaeria maculans | 51.2 | 1e-80 | 250 |
| LLPS-Miv-0792 | Microbotryum violaceum | 50.56 | 4e-53 | 179 |
| LLPS-Cym-0317 | Cyanidioschyzon merolae | 49.16 | 1e-81 | 252 |
| LLPS-Scs-0639 | Sclerotinia sclerotiorum | 47.98 | 2e-46 | 159 |
| LLPS-Vir-1480 | Vigna radiata | 43.99 | 4e-63 | 205 |
| LLPS-Cog-0919 | Colletotrichum gloeosporioides | 42.58 | 2e-55 | 184 |
| LLPS-Phn-0938 | Phaeosphaeria nodorum | 38.46 | 2e-16 | 79.7 |