• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Scf-3730
Z043_100671

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Cyclin-dependent kinase inhibitor 3
Gene Name: Z043_100671
Ensembl Gene: ENSSFOG00015008547.1
Ensembl Protein: ENSSFOP00015013289.1
Organism: Scleropages formosus
Taxa ID: 113540
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Centrosome/Spindle pole bodyPredicted from orthologs(View)

▼ FUNCTION

May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MRTTEFDSSD  EEDVGEEQQT  PLQISWLPLS  VVECSQFLGI  CPLPGCKFKD  VRRNLPKDVD  60
61    ELKDQGVEDV  FVFCTLGELQ  KYRVPRLLDV  YRQQGLRVHH  LPFPDGGTPE  LDQCSRILEE  120
121   LQFNLENNRK  TVIHCYGGLG  RSGLMAGCLL  LQLSVSMTPD  KAIEILRELR  GGGAIQTVKQ  180
181   YNFLHEFREK  YAAYQENKEV  LLERSVSR  208
Nucleotide CDS Sequence (FASTA)
1     ATGAGGACCA  CAGAGTTTGA  TTCATCTGAT  GAAGAAGATG  TGGGAGAGGA  GCAGCAAACT  60
61    CCCCTGCAGA  TCTCCTGGTT  ACCCCTGTCA  GTTGTGGAAT  GCTCACAGTT  TTTAGGAATA  120
121   TGTCCATTGC  CAGGGTGTAA  ATTCAAAGAT  GTCAGAAGAA  ACTTACCAAA  GGATGTAGAT  180
181   GAGTTAAAGG  ACCAGGGAGT  GGAGGATGTG  TTTGTGTTTT  GCACTCTTGG  GGAGCTCCAG  240
241   AAGTACCGTG  TTCCCCGGTT  GCTGGATGTT  TACCGTCAGC  AAGGACTCAG  AGTGCATCAC  300
301   CTGCCCTTCC  CTGATGGGGG  CACACCTGAG  CTTGACCAGT  GCAGCCGAAT  TCTGGAGGAA  360
361   CTGCAGTTCA  ACCTCGAGAA  CAACCGAAAA  ACAGTCATTC  ATTGCTATGG  AGGTCTTGGT  420
421   CGTTCAGGAC  TAATGGCTGG  ATGCCTCTTG  CTTCAGCTTT  CTGTCAGTAT  GACACCCGAC  480
481   AAAGCTATTG  AAATCCTGCG  TGAGTTAAGA  GGGGGTGGAG  CCATTCAGAC  AGTTAAGCAA  540
541   TACAACTTCC  TGCATGAATT  TCGAGAGAAG  TATGCAGCTT  ACCAGGAAAA  CAAAGAGGTT  600
601   TTGTTGGAGC  GATCAGTTTC  ACGATGA  627

▼ KEYWORD

ID
Family
Cell cycle
Coiled coil
Complete proteome
Cytoplasm
Hydrolase
Kinase
Protein phosphatase
Reference proteome
Transferase

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Perinuclear region of cytoplasm
Molecular Function
Kinase activity
Molecular Function
Protein tyrosine phosphatase activity
Biological Process
Cell cycle

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Leo-1705Lepisosteus oculatus80.293e-120 347
LLPS-Dar-1225Danio rerio77.883e-115 334
LLPS-Asm-0191Astyanax mexicanus76.921e-109 320
LLPS-Tar-1170Takifugu rubripes75.923e-104 306
LLPS-Xim-4118Xiphophorus maculatus74.527e-112 326
LLPS-Pof-1709Poecilia formosa74.525e-114 331
LLPS-Scm-3080Scophthalmus maximus74.164e-114 332
LLPS-Orn-1558Oreochromis niloticus74.046e-112 326
LLPS-Icp-2350Ictalurus punctatus73.815e-105 308
LLPS-Gaa-2746Gasterosteus aculeatus72.963e-104 306
LLPS-Ten-3697Tetraodon nigroviridis72.125e-100 296
LLPS-Orl-2219Oryzias latipes68.97e-99 293
LLPS-Mum-4691Mus musculus68.047e-87 262
LLPS-Ran-1975Rattus norvegicus67.534e-94 281
LLPS-Eqc-0766Equus caballus67.011e-93 280
LLPS-Mea-2153Mesocricetus auratus66.492e-85 258
LLPS-Mup-3866Mustela putorius furo66.493e-94 281
LLPS-Fec-3080Felis catus66.492e-94 281
LLPS-Urm-3573Ursus maritimus66.493e-94 281
LLPS-Sus-4649Sus scrofa66.485e-84 255
LLPS-Sah-2454Sarcophilus harrisii66.352e-91 273
LLPS-Aon-0246Aotus nancymaae65.981e-92 277
LLPS-Caj-0546Callithrix jacchus65.981e-92 277
LLPS-Aim-1953Ailuropoda melanoleuca65.982e-93 278
LLPS-Lac-1141Latimeria chalumnae65.872e-94 281
LLPS-Mod-2438Monodelphis domestica65.871e-91 274
LLPS-Loa-0957Loxodonta africana65.483e-92 276
LLPS-Cea-3245Cercocebus atys65.462e-91 274
LLPS-Orc-0339Oryctolagus cuniculus65.463e-90 271
LLPS-Ict-3582Ictidomys tridecemlineatus65.463e-86 261
LLPS-Pes-1849Pelodiscus sinensis65.034e-84 254
LLPS-Tut-2455Tursiops truncatus64.953e-91 273
LLPS-Mal-4735Mandrillus leucophaeus64.953e-83 253
LLPS-Cas-1056Carlito syrichta64.958e-91 272
LLPS-Caf-1991Canis familiaris64.99e-97 287
LLPS-Fud-3213Fukomys damarensis64.438e-89 267
LLPS-Pap-1200Pan paniscus64.426e-94 280
LLPS-Pat-4798Pan troglodytes64.426e-94 280
LLPS-Gog-1968Gorilla gorilla63.941e-93 279
LLPS-Chs-0016Chlorocebus sabaeus63.461e-92 277
LLPS-Maf-2321Macaca fascicularis63.464e-93 278
LLPS-Paa-3810Papio anubis63.464e-93 278
LLPS-Man-4309Macaca nemestrina63.464e-93 278
LLPS-Poa-4008Pongo abelii63.464e-93 278
LLPS-Mam-4642Macaca mulatta63.464e-93 278
LLPS-Cap-0463Cavia porcellus63.45e-82 250
LLPS-Hos-0410Homo sapiens62.984e-92 276
LLPS-Otg-2517Otolemur garnettii62.987e-95 282
LLPS-Rhb-3006Rhinopithecus bieti62.982e-92 276
LLPS-Nol-0524Nomascus leucogenys62.986e-85 257
LLPS-Meg-2572Meleagris gallopavo62.641e-75 233
LLPS-Dio-3772Dipodomys ordii62.421e-63 201
LLPS-Gaga-4024Gallus gallus62.021e-85 259
LLPS-Fia-2705Ficedula albicollis61.581e-84 258
LLPS-Tag-2358Taeniopygia guttata61.582e-85 259
LLPS-Anc-3570Anolis carolinensis60.587e-83 252
LLPS-Ora-3491Ornithorhynchus anatinus56.525e-69 216
LLPS-Ova-4404Ovis aries54.643e-66 208
LLPS-Bot-2606Bos taurus53.091e-63 201
LLPS-Myl-4186Myotis lucifugus50.523e-61 195
LLPS-Anp-2112Anas platyrhynchos50.434e-27 105
LLPS-Mae-1794Manihot esculenta33.633e-0650.8
LLPS-Abg-1706Absidia glauca33.612e-0752.8
LLPS-Chr-1143Chlamydomonas reinhardtii32.984e-0959.7
LLPS-Yal-0005Yarrowia lipolytica29.73e-0753.9
LLPS-Cae-1573Caenorhabditis elegans26.241e-0755.1