LLPS-Fec-3080
CDKN3
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Cyclin-dependent kinase inhibitor 3 |
| Gene Name: | CDKN3 |
| Ensembl Gene: | ENSFCAG00000015089.5 |
| Ensembl Protein: | ENSFCAP00000044242.1 |
| Organism: | Felis catus |
| Taxa ID: | 9685 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Centrosome/Spindle pole body | Predicted from orthologs | (View) |
▼ FUNCTION
| May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSFCAT00000060786.1 | ENSFCAP00000044242.1 |
| Ensembl | ENSFCAT00000039267.2 | ENSFCAP00000033953.2 |
| Ensembl | ENSFCAT00000044941.2 | ENSFCAP00000034865.2 |
| Ensembl | ENSFCAT00000063229.1 | ENSFCAP00000050212.1 |
| Ensembl | ENSFCAT00000015093.5 | ENSFCAP00000013996.5 |
| Ensembl | ENSFCAT00000050932.1 | ENSFCAP00000044686.1 |
| UniProt | A0A2I2UNM5, A0A2I2UNM5_FELCA | |
| GeneBank | AANG04004459 | |
| RefSeq | XM_003987646.3 | XP_003987695.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MKPPSSLQTS EFDSSDEEPI EDEQTPMQIS WLPLSRVNCS QFLGLCALPG CKFKNVRRNI 60 61 QKDTEELKSY GIQDIFVFCT RGELSKYRVP NLLDLYHQYG IITHHHPIPD GGTPNIASCC 120 121 EIMEELAICL KNNRKTLIHC YGGLGRSCLV AACLLLYLSD TVSPEQAIDS LRDLRGSGAI 180 181 QTIKQYNYLH EFRDKLAAHL SSRDSLSRSV SR 212 |
| Nucleotide CDS Sequence (FASTA) |
1 CTGAATCCCT GTTGTAAATT TAAAAATGTT AGAAGAAATA TCCAAAAAGA TACAGAAGAA 60 61 CTAAAGAGCT ATGGTATACA AGACATATTT GTTTTCTGCA CCAGAGGGGA ACTGTCAAAA 120 121 TACAGAGTCC CAAACCTTTT GGACCTCTAC CATCAGTATG GAATTATCAC TCATCATCAT 180 181 CCAATCCCAG ATGGAGGGAC TCCTAACATA GCCAGCTGCT GTGAAATAAT GGAGGAGCTC 240 241 GCAATCTGCC TTAAGAATAA CCGGAAAACC TTAATACACT GTTATGGAGG ACTTGGAAGA 300 301 TCTTGTCTTG TAGCCGCTTG TCTCCTACTA TACCTGTCTG ACACAGTTTC ACCAGAGCAA 360 361 GCCATAGACA GCCTGAGAGA CCTAAGAGGA TCTGGGGCAA TACAGACTAT AAAGCAATAT 420 421 AATTATCTTC ATGAGTTTCG GGACAAACTA GCTGCACATC TATCATCAAG AGATTCATTA 480 481 TCAAGATCTG TATCTAGATA A 501 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Perinuclear region of cytoplasm | |
Molecular Function | Protein tyrosine phosphatase activity | |
Biological Process | Cell cycle |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Urm-3573 | Ursus maritimus | 98.49 | 1e-145 | 412 |
| LLPS-Caf-1991 | Canis familiaris | 97.99 | 8e-145 | 409 |
| LLPS-Mup-3866 | Mustela putorius furo | 97.99 | 4e-144 | 408 |
| LLPS-Aim-1953 | Ailuropoda melanoleuca | 96.43 | 2e-140 | 398 |
| LLPS-Eqc-0766 | Equus caballus | 94.47 | 2e-139 | 395 |
| LLPS-Tut-2455 | Tursiops truncatus | 94.47 | 1e-139 | 396 |
| LLPS-Sus-4649 | Sus scrofa | 94.02 | 2e-126 | 363 |
| LLPS-Loa-0957 | Loxodonta africana | 93.97 | 9e-137 | 389 |
| LLPS-Caj-0546 | Callithrix jacchus | 93.97 | 4e-137 | 390 |
| LLPS-Man-4309 | Macaca nemestrina | 93.47 | 5e-137 | 390 |
| LLPS-Poa-4008 | Pongo abelii | 93.47 | 5e-137 | 390 |
| LLPS-Mam-4642 | Macaca mulatta | 93.47 | 5e-137 | 390 |
| LLPS-Maf-2321 | Macaca fascicularis | 93.47 | 5e-137 | 390 |
| LLPS-Cea-3245 | Cercocebus atys | 93.47 | 5e-136 | 387 |
| LLPS-Paa-3810 | Papio anubis | 93.47 | 5e-137 | 390 |
| LLPS-Rhb-3006 | Rhinopithecus bieti | 92.96 | 3e-136 | 388 |
| LLPS-Chs-0016 | Chlorocebus sabaeus | 92.96 | 1e-135 | 386 |
| LLPS-Dio-3772 | Dipodomys ordii | 92.65 | 3e-89 | 267 |
| LLPS-Pat-4798 | Pan troglodytes | 92.46 | 4e-136 | 387 |
| LLPS-Pap-1200 | Pan paniscus | 92.46 | 4e-136 | 387 |
| LLPS-Hos-0410 | Homo sapiens | 92.46 | 3e-135 | 385 |
| LLPS-Aon-0246 | Aotus nancymaae | 92.46 | 5e-135 | 385 |
| LLPS-Gog-1968 | Gorilla gorilla | 92.46 | 3e-136 | 388 |
| LLPS-Nol-0524 | Nomascus leucogenys | 91.96 | 6e-125 | 359 |
| LLPS-Mal-4735 | Mandrillus leucophaeus | 91.96 | 2e-124 | 358 |
| LLPS-Otg-2517 | Otolemur garnettii | 91.84 | 7e-135 | 384 |
| LLPS-Ict-3582 | Ictidomys tridecemlineatus | 91.46 | 5e-126 | 362 |
| LLPS-Orc-0339 | Oryctolagus cuniculus | 90.95 | 2e-131 | 376 |
| LLPS-Cas-1056 | Carlito syrichta | 90.31 | 7e-131 | 374 |
| LLPS-Ran-1975 | Rattus norvegicus | 89.95 | 7e-134 | 382 |
| LLPS-Mea-2153 | Mesocricetus auratus | 88.94 | 3e-122 | 352 |
| LLPS-Mum-4691 | Mus musculus | 88.44 | 2e-123 | 355 |
| LLPS-Fud-3213 | Fukomys damarensis | 86.93 | 9e-127 | 364 |
| LLPS-Mod-2438 | Monodelphis domestica | 85.93 | 2e-118 | 343 |
| LLPS-Sah-2454 | Sarcophilus harrisii | 85.93 | 2e-119 | 345 |
| LLPS-Cap-0463 | Cavia porcellus | 85.43 | 2e-115 | 335 |
| LLPS-Ova-4404 | Ovis aries | 76.38 | 1e-102 | 301 |
| LLPS-Pes-1849 | Pelodiscus sinensis | 75.15 | 5e-94 | 280 |
| LLPS-Bot-2606 | Bos taurus | 73.87 | 2e-97 | 288 |
| LLPS-Myl-4186 | Myotis lucifugus | 71.94 | 4e-93 | 276 |
| LLPS-Anc-3570 | Anolis carolinensis | 71.79 | 1e-99 | 295 |
| LLPS-Fia-2705 | Ficedula albicollis | 71.28 | 1e-97 | 291 |
| LLPS-Tag-2358 | Taeniopygia guttata | 69.39 | 5e-100 | 296 |
| LLPS-Lac-1141 | Latimeria chalumnae | 69.07 | 8e-94 | 280 |
| LLPS-Meg-2572 | Meleagris gallopavo | 68.12 | 7e-81 | 247 |
| LLPS-Gaga-4024 | Gallus gallus | 68.04 | 7e-93 | 278 |
| LLPS-Scf-3730 | Scleropages formosus | 66.49 | 2e-94 | 281 |
| LLPS-Ora-3491 | Ornithorhynchus anatinus | 64.8 | 3e-87 | 263 |
| LLPS-Orn-1558 | Oreochromis niloticus | 63.92 | 9e-89 | 267 |
| LLPS-Gaa-2746 | Gasterosteus aculeatus | 63.64 | 2e-82 | 251 |
| LLPS-Leo-1705 | Lepisosteus oculatus | 62.56 | 7e-94 | 280 |
| LLPS-Scm-3080 | Scophthalmus maximus | 62.24 | 3e-91 | 273 |
| LLPS-Xim-4118 | Xiphophorus maculatus | 61.9 | 1e-88 | 267 |
| LLPS-Tar-1170 | Takifugu rubripes | 61.71 | 6e-81 | 247 |
| LLPS-Pof-1709 | Poecilia formosa | 61.34 | 7e-92 | 275 |
| LLPS-Dar-1225 | Danio rerio | 61.34 | 2e-86 | 261 |
| LLPS-Asm-0191 | Astyanax mexicanus | 61.34 | 2e-83 | 253 |
| LLPS-Orl-2219 | Oryzias latipes | 60.61 | 5e-86 | 260 |
| LLPS-Icp-2350 | Ictalurus punctatus | 59.49 | 3e-83 | 253 |
| LLPS-Ten-3697 | Tetraodon nigroviridis | 59.43 | 7e-77 | 237 |
| LLPS-Anp-2112 | Anas platyrhynchos | 51.75 | 1e-28 | 110 |
| LLPS-Chr-1143 | Chlamydomonas reinhardtii | 34.52 | 6e-07 | 53.5 |
| LLPS-Abg-1040 | Absidia glauca | 27.17 | 6e-09 | 58.5 |