DrLLPS - Data resource of LLPS

LLPS-Fuo-1080
ADK2

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	GTP:AMP phosphotransferase, mitochondrial; Adenylate kinase 3; AK 3
Gene Name:	ADK2, FOXG_05770
Ensembl Gene:	FOXG_05770
Ensembl Protein:	FOXG_05770P0
Organism:	Fusarium oxysporum
Taxa ID:	426428
LLPS Type:	Client

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Nucleolus, Others	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Homo sapiens	LLPS-Hos-1278	Q9UIJ7	Client	Nucleolus, Postsynaptic density	99.71	0.0	2496

▼ FUNCTION

Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	FOXG_05770T0	FOXG_05770P0
UniProt		A0A0D2XP83, A0A0D2XP83_FUSO4
GeneBank	DS231701	KNB03212.1
RefSeq	XM_018384205.1	XP_018241257.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MNLNKAARVI LFGAPGVGKG TQSERLLARF PQLNQISTGD LLRRNVKERT PLGIKVENTM 60 61 KSGGLVADDL ILRLISNEFF TRGWLAKNGG PNVMTLSSEA TAMEASFNSA ASDPFINAPF 120 121 LDGHRPSKAS NDPSASFILD GFPRTASQVG PLDKLIPINL VVSLKTPVSV ILERILGRWV 180 181 HEPSGRVYNT SFNAPRVPGI DDVTGERLIQ RPDDSEEVYR ARYKKFQETS EPVLNHYAQK 240 241 GVLVEIEGMS SDEITPKLFA EFEKRFVH 268
Nucleotide CDS Sequence (FASTA)
1 ATGAACCTGA ACAAGGCCGC TCGCGTCATC CTCTTTGGTG CACCTGGCGT TGGTAAAGGG 60 61 ACCCAGAGCG AGCGATTGCT CGCTCGCTTT CCTCAGCTCA ATCAGATCAG TACTGGTGAT 120 121 CTCTTGCGTC GGAATGTCAA GGAGAGGACA CCCCTCGGCA TCAAGGTCGA GAATACGATG 180 181 AAGTCGGGTG GTCTTGTTGC TGATGACCTT ATTCTGCGAC TTATTTCCAA CGAATTCTTC 240 241 ACTCGAGGCT GGCTTGCGAA GAATGGTGGT CCGAACGTCA TGACTCTTTC TTCTGAAGCG 300 301 ACGGCGATGG AGGCTTCTTT CAATAGCGCT GCTTCTGATC CGTTCATCAA CGCTCCATTC 360 361 CTCGACGGGC ACCGTCCTTC CAAGGCCTCC AACGACCCAT CCGCCTCGTT CATTCTCGAT 420 421 GGTTTCCCTC GAACAGCTTC CCAAGTCGGC CCTCTCGACA AGCTTATCCC GATCAATCTC 480 481 GTAGTCTCGC TCAAGACCCC CGTATCTGTT ATTCTCGAGC GAATCCTCGG ACGTTGGGTC 540 541 CACGAGCCAT CGGGCCGAGT CTACAACACC AGCTTCAATG CGCCTCGAGT CCCCGGAATC 600 601 GACGACGTCA CCGGCGAGCG ATTAATCCAG CGCCCCGATG ATTCCGAGGA AGTTTACAGA 660 661 GCACGATACA AGAAGTTCCA AGAGACCAGC GAGCCTGTTC TGAACCACTA CGCCCAGAAG 720 721 GGCGTCCTTG TCGAGATTGA GGGCATGAGC AGCGATGAAA TCACCCCAAA GCTATTTGCA 780 781 GAGTTCGAGA AGCGCTTCGT CCAT 804

▼ KEYWORD

ID	Family
KW-0181	Complete proteome
KW-0342	GTP-binding
KW-0418	Kinase
KW-0496	Mitochondrion
KW-0547	Nucleotide-binding
KW-1185	Reference proteome
KW-0808	Transferase

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0005759	Cellular Component	Mitochondrial matrix
GO:0004017	Molecular Function	Adenylate kinase activity
GO:0005524	Molecular Function	ATP binding
GO:0005525	Molecular Function	GTP binding
GO:0046899	Molecular Function	Nucleoside triphosphate adenylate kinase activity
GO:0006172	Biological Process	ADP biosynthetic process
GO:0046033	Biological Process	AMP metabolic process
GO:0046039	Biological Process	GTP metabolic process
GO:0046041	Biological Process	ITP metabolic process

▼ KEGG

fox:FOXG_05770

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Fuv-1567	Fusarium verticillioides	99.25	0.0	543
LLPS-Trv-0881	Trichoderma virens	73.13	1e-136	393
LLPS-Trr-1267	Trichoderma reesei	69.78	4e-130	377
LLPS-Ved-1011	Verticillium dahliae	69.29	9e-130	376
LLPS-Beb-1195	Beauveria bassiana	68.16	1e-125	365
LLPS-Nec-0532	Neurospora crassa	68.01	4e-127	369
LLPS-Cog-1010	Colletotrichum gloeosporioides	66.79	4e-122	356
LLPS-Mao-0776	Magnaporthe oryzae	66.42	5e-124	361
LLPS-Scs-0976	Sclerotinia sclerotiorum	65.06	8e-119	348
LLPS-Asn-0603	Aspergillus nidulans	56.77	5e-92	279
LLPS-Asc-1270	Aspergillus clavatus	56.39	2e-98	295
LLPS-Asfu-1656	Aspergillus fumigatus	56.02	5e-97	292
LLPS-Pytr-1490	Pyrenophora triticirepentis	55.85	2e-96	291
LLPS-Nef-1364	Neosartorya fischeri	55.64	6e-97	291
LLPS-Blg-1451	Blumeria graminis	55.26	4e-96	290
LLPS-Aso-0797	Aspergillus oryzae	54.89	2e-93	282
LLPS-Asf-1519	Aspergillus flavus	54.89	2e-93	282
LLPS-Dos-0034	Dothistroma septosporum	54.72	6e-98	295
LLPS-Ast-1002	Aspergillus terreus	54.34	3e-96	289
LLPS-Asni-0834	Aspergillus niger	53.76	4e-95	286
LLPS-Zyt-1373	Zymoseptoria tritici	52.83	6e-91	276
LLPS-Tum-0311	Tuber melanosporum	49.62	5e-80	249
LLPS-Myl-1581	Myotis lucifugus	45.38	8e-35	129
LLPS-Miv-1526	Microbotryum violaceum	40.25	4e-43	159
LLPS-Sac-0959	Saccharomyces cerevisiae	39.68	2e-54	182
LLPS-Yal-0201	Yarrowia lipolytica	39.46	8e-55	183
LLPS-Tar-3627	Takifugu rubripes	37.97	4e-50	171
LLPS-Brn-2977	Brassica napus	37.4	1e-44	157
LLPS-Bro-1971	Brassica oleracea	37.4	1e-44	157
LLPS-Brr-1705	Brassica rapa	37.4	1e-44	157
LLPS-Gor-2584	Gossypium raimondii	37.3	2e-43	154
LLPS-Kop-1236	Komagataella pastoris	36.98	1e-53	180
LLPS-Mua-1517	Musa acuminata	36.95	2e-43	154
LLPS-Sol-1626	Solanum lycopersicum	36.69	2e-44	156
LLPS-Mae-1823	Manihot esculenta	36.69	1e-44	157
LLPS-Scf-3033	Scleropages formosus	36.68	2e-48	166
LLPS-Ten-1399	Tetraodon nigroviridis	36.67	1e-40	145
LLPS-Arl-1016	Arabidopsis lyrata	36.59	1e-44	157
LLPS-Thc-2053	Theobroma cacao	36.59	1e-41	149
LLPS-Php-2000	Physcomitrella patens	36.59	3e-42	150
LLPS-Nia-1810	Nicotiana attenuata	36.59	1e-45	160
LLPS-Pof-3756	Poecilia formosa	36.47	9e-51	172
LLPS-Via-1422	Vigna angularis	36.29	3e-38	141
LLPS-Viv-1785	Vitis vinifera	36.29	1e-42	152
LLPS-Sem-2390	Selaginella moellendorffii	36.18	2e-41	148
LLPS-Prp-1204	Prunus persica	36.18	2e-43	154
LLPS-Dar-0586	Danio rerio	36.09	6e-48	165
LLPS-Sot-0077	Solanum tuberosum	36.07	7e-42	150
LLPS-Pot-2608	Populus trichocarpa	35.85	2e-43	154
LLPS-Orm-1071	Oryza meridionalis	35.77	2e-42	151
LLPS-Orbr-2188	Oryza brachyantha	35.77	7e-43	152
LLPS-Anc-3590	Anolis carolinensis	35.74	1e-44	156
LLPS-Amt-1607	Amborella trichopoda	35.6	2e-42	151
LLPS-Orl-1150	Oryzias latipes	35.52	3e-45	158
LLPS-Lep-2363	Leersia perrieri	35.48	7e-44	155
LLPS-Sei-2131	Setaria italica	35.48	4e-44	156
LLPS-Orp-1205	Oryza punctata	35.48	9e-44	154
LLPS-Gaa-2067	Gasterosteus aculeatus	35.47	6e-47	162
LLPS-Asm-3798	Astyanax mexicanus	35.45	6e-50	170
LLPS-Cus-0610	Cucumis sativus	35.37	1e-41	149
LLPS-Art-2486	Arabidopsis thaliana	35.37	1e-43	154
LLPS-Otg-4576	Otolemur garnettii	35.27	4e-46	160
LLPS-Dio-0241	Dipodomys ordii	35.22	1e-39	142
LLPS-Cym-0813	Cyanidioschyzon merolae	35.16	2e-40	146
LLPS-Icp-2366	Ictalurus punctatus	35.14	3e-46	160
LLPS-Xet-0374	Xenopus tropicalis	35.14	8e-47	162
LLPS-Leo-3702	Lepisosteus oculatus	35.09	8e-48	165
LLPS-Orgl-0879	Oryza glumaepatula	35.08	4e-43	153
LLPS-Met-1477	Medicago truncatula	35.08	3e-42	150
LLPS-Ori-1133	Oryza indica	35.08	4e-43	153
LLPS-Orb-0077	Oryza barthii	35.08	4e-43	153
LLPS-Orni-1021	Oryza nivara	35.08	4e-43	153
LLPS-Orr-0252	Oryza rufipogon	35.08	4e-43	153
LLPS-Org-0580	Oryza glaberrima	35.08	4e-43	153
LLPS-Ors-0513	Oryza sativa	35.08	4e-43	153
LLPS-Put-0435	Puccinia triticina	35.02	9e-43	154
LLPS-Xim-3858	Xiphophorus maculatus	34.96	3e-42	150
LLPS-Sob-1462	Sorghum bicolor	34.96	1e-41	149
LLPS-Fec-2857	Felis catus	34.88	3e-45	158
LLPS-Coc-2071	Corchorus capsularis	34.83	3e-44	155
LLPS-Aim-3521	Ailuropoda melanoleuca	34.78	1e-42	151
LLPS-Drm-1003	Drosophila melanogaster	34.77	3e-40	144
LLPS-Lac-0818	Latimeria chalumnae	34.75	3e-45	158
LLPS-Chr-1589	Chlamydomonas reinhardtii	34.73	2e-43	154
LLPS-Vir-0508	Vigna radiata	34.69	1e-36	135
LLPS-Pug-1384	Puccinia graminis	34.66	3e-42	152
LLPS-Mup-1498	Mustela putorius furo	34.5	5e-41	147
LLPS-Mal-1706	Mandrillus leucophaeus	34.5	2e-45	158
LLPS-Paa-3663	Papio anubis	34.5	2e-45	158
LLPS-Cea-4707	Cercocebus atys	34.5	2e-45	158
LLPS-Chs-1846	Chlorocebus sabaeus	34.5	2e-45	158
LLPS-Mea-3170	Mesocricetus auratus	34.5	2e-46	161
LLPS-Mum-4427	Mus musculus	34.5	4e-46	160
LLPS-Maf-4062	Macaca fascicularis	34.5	2e-45	158
LLPS-Mam-3079	Macaca mulatta	34.5	2e-45	158
LLPS-Rhb-2771	Rhinopithecus bieti	34.5	2e-45	158
LLPS-Crn-0082	Cryptococcus neoformans	34.44	4e-38	142
LLPS-Mel-1052	Melampsora laricipopulina	34.38	2e-45	164
LLPS-Orc-2157	Oryctolagus cuniculus	34.36	2e-45	159
LLPS-Tru-0420	Triticum urartu	34.3	2e-38	141
LLPS-Gag-1143	Gaeumannomyces graminis	34.29	9e-38	140
LLPS-Brd-1286	Brachypodium distachyon	34.27	3e-42	150
LLPS-Tra-2488	Triticum aestivum	34.27	2e-41	148
LLPS-Glm-1627	Glycine max	34.27	2e-41	149
LLPS-Spr-1550	Sporisorium reilianum	34.27	8e-42	150
LLPS-Usm-1146	Ustilago maydis	34.27	6e-46	162
LLPS-Phv-1102	Phaseolus vulgaris	34.27	1e-41	149
LLPS-Hov-1716	Hordeum vulgare	34.15	1e-38	143
LLPS-Hea-0536	Helianthus annuus	34.15	1e-40	147
LLPS-Osl-0221	Ostreococcus lucimarinus	34.15	2e-40	145
LLPS-Ran-1148	Rattus norvegicus	34.11	4e-45	158
LLPS-Gog-2340	Gorilla gorilla	34.11	3e-44	155
LLPS-Eqc-3895	Equus caballus	34.11	6e-45	157
LLPS-Poa-3305	Pongo abelii	34.11	3e-44	155
LLPS-Nol-3890	Nomascus leucogenys	34.11	1e-44	156
LLPS-Hos-1278	Homo sapiens	34.11	3e-44	155
LLPS-Cii-1777	Ciona intestinalis	33.98	4e-41	147
LLPS-Gaga-2281	Gallus gallus	33.98	2e-43	154
LLPS-Scm-2939	Scophthalmus maximus	33.98	8e-37	136
LLPS-Mod-2884	Monodelphis domestica	33.98	4e-45	157
LLPS-Cap-3561	Cavia porcellus	33.85	4e-45	158
LLPS-Orn-3212	Oreochromis niloticus	33.83	1e-42	151
LLPS-Zem-1836	Zea mays	33.74	1e-41	149
LLPS-Sus-3963	Sus scrofa	33.72	3e-44	155
LLPS-Caj-4220	Callithrix jacchus	33.72	1e-43	154
LLPS-Caf-0197	Canis familiaris	33.72	6e-42	149
LLPS-Ict-4296	Ictidomys tridecemlineatus	33.72	1e-45	159
LLPS-Pat-4933	Pan troglodytes	33.72	4e-43	152
LLPS-Scj-0014	Schizosaccharomyces japonicus	33.61	1e-35	132
LLPS-Bot-1076	Bos taurus	33.59	1e-43	154
LLPS-Ova-2825	Ovis aries	33.59	2e-43	154
LLPS-Pes-0746	Pelodiscus sinensis	33.59	1e-42	151
LLPS-Coo-0474	Colletotrichum orbiculare	33.47	3e-36	136
LLPS-Urm-3658	Ursus maritimus	33.46	2e-41	147
LLPS-Aon-3970	Aotus nancymaae	33.33	6e-43	152
LLPS-Sah-3547	Sarcophilus harrisii	32.95	3e-40	145
LLPS-Cogr-0943	Colletotrichum graminicola	32.92	2e-35	133
LLPS-Fia-3500	Ficedula albicollis	32.82	1e-42	151
LLPS-Phn-0119	Phaeosphaeria nodorum	32.79	1e-37	140
LLPS-Cis-0940	Ciona savignyi	32.71	6e-41	147
LLPS-Fus-0783	Fusarium solani	32.5	1e-36	136
LLPS-Pyt-0219	Pyrenophora teres	32.26	4e-37	138
LLPS-Map-0357	Magnaporthe poae	32.24	3e-36	136
LLPS-Tag-1355	Taeniopygia guttata	32.05	3e-42	150
LLPS-Loa-2990	Loxodonta africana	31.94	3e-42	150
LLPS-Pap-4062	Pan paniscus	31.94	2e-42	150
LLPS-Scp-0879	Schizosaccharomyces pombe	31.7	5e-35	131
LLPS-Man-0088	Macaca nemestrina	31.58	4e-36	134
LLPS-Lem-1164	Leptosphaeria maculans	31.2	1e-35	134
LLPS-Ere-0880	Erinaceus europaeus	30.83	9e-36	134
LLPS-Cas-0912	Carlito syrichta	30.83	4e-35	132
LLPS-Fud-1820	Fukomys damarensis	30.8	8e-35	131
LLPS-Abg-0576	Absidia glauca	30.12	7e-36	134
LLPS-Asg-1224	Ashbya gossypii	30.12	3e-36	135

LLPS-Fuo-1080ADK2

Protein Sequence

Nucleotide Sequence

LLPS-Fuo-1080
ADK2