DrLLPS - Data resource of LLPS

LLPS-Art-2486
ADK1

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	Adenylate kinase 4
Gene Name:	ADK1, At5g63400, MLE2.3
Ensembl Gene:	AT5G63400
Ensembl Protein:	AT5G63400.2
Organism:	Arabidopsis thaliana
Taxa ID:	3702
LLPS Type:	Others

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Droplet, Nucleolus	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Saccharomyces cerevisiae	LLPS-Sac-0495	P07170	Client	Droplet	53.30	1e-81	251
Homo sapiens	LLPS-Hos-0656	P54819	Client	Nucleolus	53.30	3e-81	250

▼ FUNCTION

Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	AT5G63400.2	AT5G63400.2
Ensembl	AT5G63400.1	AT5G63400.1
UniProt		O82514, KAD4_ARATH, Q9FMW2
GeneBank	AB007649, AF082882, CP002688, AY085188, AY079340, AY039945	AED97743.1, AAK64049.1, AAM61739.1, AAL85071.1, AAC78478.1, BAB08805.1
RefSeq	NM_125735.4	NP_201145.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MATGGAAADL EDVQTVDLMS ELLRRLKCSQ KPDKRLIFIG PPGSGKGTQS PVVKDEYCLC 60 61 HLSTGDMLRA AVASKTPLGV KAKEAMEKGE LVSDDLVVGI IDEAMNKPKC QKGFILDGFP 120 121 RTVTQAEKLD EMLKRRGTEI DKVLNFAIDD AILEERITGR WIHPSSGRSY HTKFAPPKTP 180 181 GVDDITGEPL IQRKDDNADV LKSRLAAFHS QTQPVIDYYA KKAVLTNIQA EKAPQEVTSE 240 241 VKKALS 246
Nucleotide CDS Sequence (FASTA)
1 ATGGCGACCG GTGGTGCTGC GGCGGATTTG GAAGATGTTC AGACGGTGGA TCTCATGTCG 60 61 GAGCTCCTCC GCCGCCTCAA GTGTTCTCAG AAGCCCGACA AACGCCTCAT CTTCATTGGA 120 121 CCTCCAGGGT CAGGGAAAGG TACTCAATCT CCAGTAGTGA AGGATGAGTA TTGCTTGTGT 180 181 CACTTATCCA CTGGAGACAT GTTAAGAGCT GCTGTTGCTT CTAAGACCCC TCTTGGTGTC 240 241 AAGGCTAAAG AAGCTATGGA AAAAGGAGAG CTCGTCTCTG ATGATTTGGT TGTTGGTATA 300 301 ATTGATGAAG CCATGAACAA GCCAAAATGT CAAAAAGGAT TTATCCTTGA TGGGTTCCCC 360 361 AGGACTGTTA CTCAGGCAGA GAAGCTCGAT GAGATGCTTA AGAGGCGAGG AACTGAAATT 420 421 GACAAAGTTC TCAACTTTGC TATTGATGAC GCAATCTTGG AGGAAAGAAT AACCGGGCGA 480 481 TGGATCCACC CATCGAGTGG CAGGAGTTAC CACACCAAAT TTGCTCCTCC CAAAACCCCT 540 541 GGAGTTGATG ATATGATAAC GCTGATGTTC TAA 573

▼ KEYWORD

ID	Family
KW-0007	Acetylation
KW-0025	Alternative splicing
KW-0067	ATP-binding
KW-0181	Complete proteome
KW-0963	Cytoplasm
KW-0418	Kinase
KW-0547	Nucleotide-binding
KW-1185	Reference proteome
KW-0808	Transferase

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0005739	Cellular Component	Mitochondrion
GO:0005774	Cellular Component	Vacuolar membrane
GO:0004017	Molecular Function	Adenylate kinase activity
GO:0005524	Molecular Function	ATP binding
GO:0005507	Molecular Function	Copper ion binding
GO:0046686	Biological Process	Response to cadmium ion

▼ KEGG

ath:AT5G63400

▼ ANNOTATION

Disorder
IUPred2A

Domain
SMART	Pfam	InterPro	CDD	PRINTS
PROSITE	Gene3D

PTM
EPSD	dbPTM	PTMcode

Physicochemical
Compute pI/Mw	AAindex

Function
PIRSF

Localization
COMPARTMENTS

Expression
ArrayExpress

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Arl-1016	Arabidopsis lyrata	98.37	3e-179	499
LLPS-Brn-2977	Brassica napus	92.47	1e-165	465
LLPS-Bro-1971	Brassica oleracea	92.47	2e-165	464
LLPS-Brr-1705	Brassica rapa	92.47	1e-165	465
LLPS-Sei-2131	Setaria italica	82.5	7e-150	426
LLPS-Pot-1410	Populus trichocarpa	82.35	2e-147	419
LLPS-Orgl-0879	Oryza glumaepatula	82.23	2e-152	432
LLPS-Orni-1021	Oryza nivara	82.23	2e-152	432
LLPS-Orb-0077	Oryza barthii	82.23	2e-152	432
LLPS-Ori-1133	Oryza indica	82.23	2e-152	432
LLPS-Org-0580	Oryza glaberrima	82.23	2e-152	432
LLPS-Orr-0252	Oryza rufipogon	82.23	2e-152	432
LLPS-Ors-0513	Oryza sativa	82.23	2e-152	432
LLPS-Cus-0610	Cucumis sativus	82.11	3e-152	431
LLPS-Brd-1286	Brachypodium distachyon	81.67	9e-149	422
LLPS-Orp-1205	Oryza punctata	81.4	4e-151	428
LLPS-Met-1477	Medicago truncatula	81.33	5e-149	423
LLPS-Prp-1204	Prunus persica	81.3	4e-152	431
LLPS-Sol-1626	Solanum lycopersicum	81.25	1e-146	417
LLPS-Lep-2363	Leersia perrieri	81.07	8e-151	427
LLPS-Orm-1071	Oryza meridionalis	81.07	6e-150	425
LLPS-Viv-1785	Vitis vinifera	81.01	9e-146	415
LLPS-Sot-0077	Solanum tuberosum	80.91	5e-147	418
LLPS-Glm-1627	Glycine max	80.91	6e-147	417
LLPS-Phv-1102	Phaseolus vulgaris	80.91	5e-147	418
LLPS-Hea-0536	Helianthus annuus	80.89	2e-150	426
LLPS-Nia-1810	Nicotiana attenuata	80.83	3e-145	413
LLPS-Orbr-2188	Oryza brachyantha	80.67	7e-146	415
LLPS-Tra-2488	Triticum aestivum	80.42	9e-148	420
LLPS-Sob-1462	Sorghum bicolor	80.42	1e-146	417
LLPS-Hov-1716	Hordeum vulgare	80.17	1e-144	415
LLPS-Gor-2584	Gossypium raimondii	80.08	1e-145	414
LLPS-Mua-1517	Musa acuminata	79.67	4e-148	421
LLPS-Mae-0067	Manihot esculenta	79.67	9e-147	417
LLPS-Zem-1836	Zea mays	79.17	8e-146	415
LLPS-Thc-2053	Theobroma cacao	78.84	3e-143	408
LLPS-Coc-2071	Corchorus capsularis	78.84	4e-142	405
LLPS-Amt-1607	Amborella trichopoda	78.51	7e-145	412
LLPS-Sem-2390	Selaginella moellendorffii	77.31	2e-139	398
LLPS-Dac-0169	Daucus carota	75.63	3e-62	197
LLPS-Tru-0420	Triticum urartu	75.49	8e-143	408
LLPS-Vir-0508	Vigna radiata	75.12	5e-114	333
LLPS-Via-1422	Vigna angularis	70.85	1e-138	398
LLPS-Php-2000	Physcomitrella patens	67.9	1e-124	361
LLPS-Osl-0221	Ostreococcus lucimarinus	67.8	3e-117	342
LLPS-Chr-1589	Chlamydomonas reinhardtii	64.44	3e-115	337
LLPS-Trr-1570	Trichoderma reesei	59.8	6e-86	263
LLPS-Map-0357	Magnaporthe poae	58.82	1e-83	258
LLPS-Trv-0307	Trichoderma virens	58.82	5e-84	258
LLPS-Abg-0576	Absidia glauca	58.37	2e-88	270
LLPS-Mao-0306	Magnaporthe oryzae	58.33	2e-83	257
LLPS-Drm-1487	Drosophila melanogaster	58.05	3e-88	268
LLPS-Coo-0474	Colletotrichum orbiculare	57.84	3e-83	256
LLPS-Gag-1143	Gaeumannomyces graminis	57.84	2e-81	252
LLPS-Beb-1240	Beauveria bassiana	57.84	7e-83	255
LLPS-Cogr-0943	Colletotrichum graminicola	57.35	2e-82	254
LLPS-Chc-1063	Chondrus crispus	57.22	6e-67	212
LLPS-Scc-1065	Schizosaccharomyces cryophilus	57.08	4e-80	247
LLPS-Gas-0935	Galdieria sulphuraria	56.96	1e-89	273
LLPS-Asn-0756	Aspergillus nidulans	56.86	4e-81	251
LLPS-Ved-0811	Verticillium dahliae	56.86	1e-82	255
LLPS-Ast-0054	Aspergillus terreus	56.86	3e-81	251
LLPS-Cii-0778	Ciona intestinalis	56.73	9e-87	264
LLPS-Pyt-0219	Pyrenophora teres	56.67	1e-81	253
LLPS-Tut-1792	Tursiops truncatus	56.49	6e-61	196
LLPS-Aso-1040	Aspergillus oryzae	56.37	1e-82	253
LLPS-Asc-1349	Aspergillus clavatus	56.37	1e-81	252
LLPS-Dos-0898	Dothistroma septosporum	56.37	7e-80	248
LLPS-Cog-0477	Colletotrichum gloeosporioides	56.37	2e-80	249
LLPS-Fuv-0733	Fusarium verticillioides	56.34	6e-84	258
LLPS-Fuo-1051	Fusarium oxysporum	56.34	6e-84	258
LLPS-Scj-0014	Schizosaccharomyces japonicus	56.13	1e-86	263
LLPS-Lem-1164	Leptosphaeria maculans	55.71	2e-80	250
LLPS-Phn-0119	Phaeosphaeria nodorum	55.24	1e-79	248
LLPS-Tum-0155	Tuber melanosporum	55.11	5e-62	200
LLPS-Fus-0783	Fusarium solani	54.93	5e-83	255
LLPS-Nec-0794	Neurospora crassa	54.9	5e-77	241
LLPS-Mel-1114	Melampsora laricipopulina	54.72	2e-78	246
LLPS-Asg-1224	Ashbya gossypii	54.72	4e-85	262
LLPS-Pug-0443	Puccinia graminis	54.72	1e-78	247
LLPS-Scs-0397	Sclerotinia sclerotiorum	54.41	1e-77	242
LLPS-Scp-0879	Schizosaccharomyces pombe	54.33	3e-81	249
LLPS-Spr-0325	Sporisorium reilianum	54.29	2e-78	245
LLPS-Kop-0574	Komagataella pastoris	54.25	1e-83	256
LLPS-Fud-1820	Fukomys damarensis	54.25	1e-83	256
LLPS-Put-0539	Puccinia triticina	54.25	4e-77	245
LLPS-Cis-0678	Ciona savignyi	53.98	4e-66	211
LLPS-Asf-1041	Aspergillus flavus	53.78	2e-83	256
LLPS-Yal-1440	Yarrowia lipolytica	53.77	2e-80	248
LLPS-Crn-1273	Cryptococcus neoformans	53.77	5e-80	248
LLPS-Aon-1751	Aotus nancymaae	53.77	1e-81	251
LLPS-Cap-3175	Cavia porcellus	53.77	4e-82	253
LLPS-Loa-1137	Loxodonta africana	53.77	8e-83	254
LLPS-Asni-0903	Aspergillus niger	53.33	9e-82	252
LLPS-Mal-1177	Mandrillus leucophaeus	53.3	3e-81	250
LLPS-Paa-4319	Papio anubis	53.3	3e-81	251
LLPS-Sac-0495	Saccharomyces cerevisiae	53.3	1e-81	251
LLPS-Gog-1595	Gorilla gorilla	53.3	1e-81	251
LLPS-Caj-3609	Callithrix jacchus	53.3	5e-81	250
LLPS-Maf-2081	Macaca fascicularis	53.3	2e-81	251
LLPS-Chs-1931	Chlorocebus sabaeus	53.3	3e-81	250
LLPS-Sus-4451	Sus scrofa	53.3	3e-82	253
LLPS-Cea-0935	Cercocebus atys	53.3	3e-81	251
LLPS-Nol-4007	Nomascus leucogenys	53.3	3e-81	250
LLPS-Ict-3594	Ictidomys tridecemlineatus	53.3	9e-82	251
LLPS-Poa-2939	Pongo abelii	53.3	3e-81	250
LLPS-Mam-0615	Macaca mulatta	53.3	3e-81	251
LLPS-Hos-0656	Homo sapiens	53.3	3e-81	250
LLPS-Pap-3346	Pan paniscus	53.3	2e-81	251
LLPS-Pat-2561	Pan troglodytes	53.3	2e-81	251
LLPS-Zyt-0167	Zymoseptoria tritici	52.88	5e-78	243
LLPS-Gaa-0312	Gasterosteus aculeatus	52.83	3e-81	251
LLPS-Dio-1985	Dipodomys ordii	52.83	1e-81	251
LLPS-Mum-3370	Mus musculus	52.83	8e-82	252
LLPS-Caf-1162	Canis familiaris	52.83	3e-81	250
LLPS-Mod-2951	Monodelphis domestica	52.83	1e-82	254
LLPS-Usm-0321	Ustilago maydis	52.61	2e-77	243
LLPS-Gaga-0344	Gallus gallus	52.53	6e-72	231
LLPS-Fia-0159	Ficedula albicollis	52.53	4e-76	236
LLPS-Meg-1031	Meleagris gallopavo	52.53	1e-74	233
LLPS-Asfu-1253	Aspergillus fumigatus	52.44	7e-81	250
LLPS-Nef-0344	Neosartorya fischeri	52.44	2e-80	249
LLPS-Ran-2593	Rattus norvegicus	52.36	2e-80	248
LLPS-Myl-1326	Myotis lucifugus	52.36	3e-79	245
LLPS-Mup-0248	Mustela putorius furo	52.36	1e-79	246
LLPS-Aim-3342	Ailuropoda melanoleuca	52.36	9e-81	249
LLPS-Tar-0250	Takifugu rubripes	52.36	2e-78	243
LLPS-Bot-3815	Bos taurus	52.36	7e-81	249
LLPS-Cae-1365	Caenorhabditis elegans	52.36	2e-76	238
LLPS-Cas-0912	Carlito syrichta	52.36	4e-80	247
LLPS-Xet-2166	Xenopus tropicalis	52.36	7e-82	252
LLPS-Eqc-2123	Equus caballus	52.36	6e-81	249
LLPS-Otg-4610	Otolemur garnettii	52.36	3e-81	250
LLPS-Orc-0029	Oryctolagus cuniculus	52.36	2e-80	248
LLPS-Urm-2137	Ursus maritimus	52.36	2e-80	248
LLPS-Scm-2399	Scophthalmus maximus	52.36	3e-81	251
LLPS-Fec-1439	Felis catus	52.36	4e-81	250
LLPS-Man-0088	Macaca nemestrina	52.36	9e-81	249
LLPS-Cym-0813	Cyanidioschyzon merolae	52.28	6e-86	263
LLPS-Ova-0681	Ovis aries	52.22	2e-75	235
LLPS-Blg-0914	Blumeria graminis	52.19	5e-81	251
LLPS-Rhb-3620	Rhinopithecus bieti	52.09	9e-75	234
LLPS-Ora-3426	Ornithorhynchus anatinus	52.02	3e-75	234
LLPS-Tag-2993	Taeniopygia guttata	52.02	1e-74	233
LLPS-Ere-0880	Erinaceus europaeus	51.89	4e-80	248
LLPS-Scf-1036	Scleropages formosus	51.89	2e-80	248
LLPS-Orl-3543	Oryzias latipes	51.89	1e-80	249
LLPS-Leo-0075	Lepisosteus oculatus	51.89	3e-81	250
LLPS-Ten-1852	Tetraodon nigroviridis	51.89	7e-78	242
LLPS-Xim-0690	Xiphophorus maculatus	51.69	6e-78	242
LLPS-Pof-1741	Poecilia formosa	51.69	2e-78	243
LLPS-Dar-2427	Danio rerio	51.42	7e-80	247
LLPS-Pes-2208	Pelodiscus sinensis	51.27	5e-71	225
LLPS-Sah-1401	Sarcophilus harrisii	51.26	1e-73	230
LLPS-Pytr-1383	Pyrenophora triticirepentis	50.95	4e-69	220
LLPS-Miv-1051	Microbotryum violaceum	50.7	3e-77	241
LLPS-Lac-3641	Latimeria chalumnae	50.51	4e-72	226
LLPS-Icp-2830	Ictalurus punctatus	50.0	6e-78	242
LLPS-Asm-0168	Astyanax mexicanus	49.53	1e-76	239
LLPS-Anc-2421	Anolis carolinensis	48.34	1e-50	169
LLPS-Mea-3170	Mesocricetus auratus	45.83	6e-55	182
LLPS-Orn-3212	Oreochromis niloticus	43.01	1e-49	169

LLPS-Art-2486ADK1

Protein Sequence

Nucleotide Sequence

LLPS-Art-2486
ADK1