LLPS-Crn-1491
TRM82
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Transfer RNA methyltransferase 82 |
| Gene Name: | TRM82, CNG02370 |
| Ensembl Gene: | CNG02370 |
| Ensembl Protein: | AAW44655 |
| Organism: | Cryptococcus neoformans |
| Taxa ID: | 214684 |
| LLPS Type: | Client |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Others | Predicted from orthologs | (View) |
▼ FUNCTION
| Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | AAW44655 | AAW44655 |
| UniProt | P0CS52, TRM82_CRYNJ, Q55PH3, Q5KDY5 | |
| GeneBank | AE017347 | AAW44655.1 |
| RefSeq | XM_571962.1 | XP_571962.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MALHCPPTAL ATSSTSLFIA AGPALHVFNP STSTFASCAA DGTGGLIRLL AVREDGEVAA 60 61 TLGEDKQLAV WDIQHDRPQF RHTRTVVKKG SCLSFAKDGS IILTDKVGDV YSYPLDPVPI 120 121 DPSAERPPMY TLVADPSQNP DATYLLGHVS MLNAHVMTPD GRRIITADRD EHIRVSRYPK 180 181 AYVIDKYLFG HDGFVSALHI PPSNPSLLLS AGGDPSLLIW NPSTGKLLTS VPVWPAVLSH 240 241 RRVRSHLRRH KPGSRKLKMD PVPEDMDEEN QTFYTAPEGY MLPSGQGVCI KKIESVKIGG 300 301 ETVVLFFSEG ASAIHSFILP TDPEGVKPTV HTLPLPHPLI DFTPIPSTSS ADEKEVLLSL 360 361 DTAWDVLKKN PGPGIEGRQD TIQRDDLSDE EKRNISKIFS VARISADGHL SLGDASVYDS 420 421 LVSNLPSTDI KTLSNVNLYP LLCVLPRWPG FEEGDEELTV NTGTPDTPGT PGPADAVSLA 480 481 PTSGAFLQKS YTQEELEKMN TKQLGRLKSA GIDVGSILLA RQKKAKEEHK ARKAAAKAKA 540 541 EAQKNQKEGG RPAKKKKKVE MSEEELANA 569 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCTCTCC ACTGCCCCCC CACCGCGCTA GCCACTAGCT CAACATCACT CTTCATCGCC 60 61 GCAGGCCCTG CGCTCCACGT GTTCAACCCT TCCACCTCCA CCTTCGCGTC GTGCGCCGCT 120 121 GATGGCACGG GAGGGCTGAT TCGGCTGCTC GCTGTGAGGG AGGACGGGGA GGTCGCCGCC 180 181 ACGCTCGGAG AGGACAAGCA ACTCGCTGTG TGGGATATCC AGCATGATAG GCCCCAGTTC 240 241 AGACACACCA GAACCGTCGT CAAGAAGGGC TCCTGTCTTT CGTTCGCCAA AGACGGATCG 300 301 ATCATCCTCA CAGACAAGGT CGGAGATGTC TACTCCTACC CGCTTGACCC TGTCCCTATC 360 361 GACCCTTCCG CCGAGAGACC GCCCATGTAC ACTCTCGTGG CTGACCCTTC TCAAAATCCG 420 421 GATGCAACCT ATCTTCTTGG TCATGTATCG ATGCTCAACG CCCATGTTAT GACGCCCGAT 480 481 GGGAGGCGAA TTATCACCGC CGACAGAGAC GAGCACATTC GTGTAAGCCG ATACCCCAAG 540 541 GCCTATGTCA TTGACAAGTA CCTCTTTGGC CACGACGGCT TTGTGTCTGC GTTACATATC 600 601 CCTCCCTCCA ACCCTTCTCT TCTTCTCTCC GCTGGTGGGG ACCCTTCTCT TCTCATCTGG 660 661 AACCCATCCA CGGGCAAGCT TCTCACGTCT GTGCCGGTCT GGCCTGCCGT CCTTTCTCAC 720 721 CGTCGGGTCC GCTCCCACCT CCGTCGACAC AAGCCTGGAT CTAGGAAACT CAAGATGGAT 780 781 CCTGTGCCGG AGGACATGGA CGAGGAGAAC CAGACGTTCT ACACTGCGCC CGAAGGTTAC 840 841 ATGTTACCTT CCGGCCAGGG CGTGTGTATC AAGAAGATTG AAAGCGTAAA GATCGGGGGA 900 901 GAGACTGTTG TGCTGTTTTT CTCTGAGGGT GCGTCGGCCA TACACTCGTT TATTTTGCCT 960 961 ACCGATCCCG AGGGCGTCAA GCCTACTGTT CACACCTTGC CTCTCCCCCA TCCCCTCATC 1020 1021 GATTTCACAC CTATCCCTTC AACATCTTCT GCCGACGAAA AAGAAGTTCT TCTTTCGCTC 1080 1081 GACACTGCCT GGGATGTGCT AAAAAAGAAT CCTGGACCCG GTATTGAAGG CCGACAAGAC 1140 1141 ACTATCCAAC GTGATGACCT CTCTGATGAG GAAAAGCGAA ATATTTCCAA GATCTTTTCA 1200 1201 GTAGCCAGGA TCTCTGCCGA TGGCCATTTA TCACTTGGTG ACGCTTCCGT TTATGACTCT 1260 1261 CTCGTTTCCA ACCTTCCCAG CACTGATATC AAGACTCTGT CCAACGTCAA CCTCTACCCT 1320 1321 CTCCTTTGTG TCCTCCCTCG CTGGCCTGGA TTTGAAGAAG GCGACGAAGA GCTCACCGTC 1380 1381 AATACTGGTA CCCCCGACAC CCCTGGCACC CCTGGTCCTG CTGATGCCGT TTCTCTCGCC 1440 1441 CCTACATCAG GTGCTTTCCT CCAGAAATCA TACACCCAAG AAGAACTGGA GAAGATGAAC 1500 1501 ACCAAGCAGC TGGGCCGCCT CAAGTCTGCA GGCATTGATG TTGGCAGTAT CTTGTTGGCC 1560 1561 AGGCAGAAGA AGGCCAAGGA GGAACACAAG GCGCGAAAAG CTGCGGCCAA AGCCAAGGCT 1620 1621 GAGGCACAAA AGAACCAGAA AGAAGGAGGT AGGCCGGCGA AGAAGAAAAA GAAGGTGGAG 1680 1681 ATGAGTGAGG AGGAGTTGGC GAATGCTTAA 1710 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Cytosol | |
Cellular Component | Nucleus | |
Cellular Component | TRNA methyltransferase complex | |
Biological Process | TRNA (guanine-N7)-methylation |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Pytr-1227 | Pyrenophora triticirepentis | 53.85 | 3e-13 | 74.3 |
| LLPS-Nec-0412 | Neurospora crassa | 50.51 | 2e-18 | 93.2 |
| LLPS-Coo-0211 | Colletotrichum orbiculare | 45.63 | 1e-16 | 87.0 |
| LLPS-Tum-1006 | Tuber melanosporum | 41.72 | 7e-20 | 94.7 |
| LLPS-Fia-0576 | Ficedula albicollis | 40.46 | 7e-18 | 89.7 |
| LLPS-Mod-0877 | Monodelphis domestica | 40.41 | 6e-21 | 99.4 |
| LLPS-Asg-0470 | Ashbya gossypii | 40.41 | 2e-22 | 104 |
| LLPS-Tag-3486 | Taeniopygia guttata | 39.69 | 1e-16 | 85.9 |
| LLPS-Sah-1154 | Sarcophilus harrisii | 39.6 | 8e-21 | 98.6 |
| LLPS-Yal-0107 | Yarrowia lipolytica | 38.97 | 6e-20 | 95.9 |
| LLPS-Meg-1997 | Meleagris gallopavo | 38.89 | 1e-19 | 94.7 |
| LLPS-Scs-0369 | Sclerotinia sclerotiorum | 38.57 | 4e-25 | 113 |
| LLPS-Anp-3054 | Anas platyrhynchos | 38.46 | 1e-16 | 85.9 |
| LLPS-Anc-3223 | Anolis carolinensis | 38.19 | 6e-12 | 72.0 |
| LLPS-Asn-0649 | Aspergillus nidulans | 38.14 | 2e-25 | 114 |
| LLPS-Gaga-1253 | Gallus gallus | 37.82 | 8e-20 | 95.9 |
| LLPS-Orl-1771 | Oryzias latipes | 37.5 | 1e-23 | 108 |
| LLPS-Leo-0024 | Lepisosteus oculatus | 37.43 | 6e-21 | 99.4 |
| LLPS-Trr-1169 | Trichoderma reesei | 37.39 | 6e-24 | 110 |
| LLPS-Kop-1207 | Komagataella pastoris | 37.16 | 1e-25 | 113 |
| LLPS-Ora-2200 | Ornithorhynchus anatinus | 36.99 | 8e-19 | 92.4 |
| LLPS-Sac-0206 | Saccharomyces cerevisiae | 36.46 | 3e-24 | 109 |
| LLPS-Caf-1214 | Canis familiaris | 36.42 | 6e-19 | 93.2 |
| LLPS-Mup-2631 | Mustela putorius furo | 36.42 | 1e-18 | 91.7 |
| LLPS-Map-0133 | Magnaporthe poae | 36.4 | 2e-23 | 108 |
| LLPS-Fuv-1174 | Fusarium verticillioides | 36.2 | 4e-25 | 113 |
| LLPS-Urm-3804 | Ursus maritimus | 36.05 | 3e-18 | 90.9 |
| LLPS-Loa-1988 | Loxodonta africana | 35.76 | 2e-19 | 94.7 |
| LLPS-Orc-3971 | Oryctolagus cuniculus | 35.76 | 6e-19 | 93.2 |
| LLPS-Aim-0502 | Ailuropoda melanoleuca | 35.76 | 9e-18 | 89.7 |
| LLPS-Myl-3186 | Myotis lucifugus | 35.76 | 3e-18 | 90.9 |
| LLPS-Cas-2682 | Carlito syrichta | 35.71 | 2e-18 | 92.0 |
| LLPS-Fuo-1232 | Fusarium oxysporum | 35.62 | 5e-26 | 115 |
| LLPS-Sus-4120 | Sus scrofa | 35.62 | 2e-18 | 92.0 |
| LLPS-Orn-2660 | Oreochromis niloticus | 35.57 | 1e-17 | 89.4 |
| LLPS-Mea-4372 | Mesocricetus auratus | 35.53 | 3e-18 | 90.1 |
| LLPS-Phn-1470 | Phaeosphaeria nodorum | 35.5 | 4e-19 | 94.7 |
| LLPS-Tar-3872 | Takifugu rubripes | 35.5 | 2e-22 | 103 |
| LLPS-Bot-4670 | Bos taurus | 35.26 | 6e-19 | 94.0 |
| LLPS-Ova-2677 | Ovis aries | 35.26 | 6e-19 | 93.2 |
| LLPS-Miv-1492 | Microbotryum violaceum | 35.23 | 6e-32 | 134 |
| LLPS-Icp-2450 | Ictalurus punctatus | 35.14 | 3e-21 | 100 |
| LLPS-Dio-3808 | Dipodomys ordii | 35.14 | 8e-17 | 86.3 |
| LLPS-Fec-4190 | Felis catus | 35.1 | 5e-17 | 88.2 |
| LLPS-Hos-3943 | Homo sapiens | 35.1 | 7e-18 | 90.1 |
| LLPS-Man-1283 | Macaca nemestrina | 35.1 | 8e-18 | 90.1 |
| LLPS-Rhb-3781 | Rhinopithecus bieti | 35.1 | 6e-18 | 90.5 |
| LLPS-Cap-3944 | Cavia porcellus | 35.1 | 3e-18 | 92.0 |
| LLPS-Poa-1540 | Pongo abelii | 35.1 | 8e-17 | 87.0 |
| LLPS-Mam-0463 | Macaca mulatta | 35.1 | 9e-18 | 89.7 |
| LLPS-Ict-0891 | Ictidomys tridecemlineatus | 35.1 | 4e-18 | 90.9 |
| LLPS-Chs-1889 | Chlorocebus sabaeus | 35.1 | 9e-18 | 89.7 |
| LLPS-Maf-3681 | Macaca fascicularis | 35.1 | 6e-18 | 90.5 |
| LLPS-Cea-3152 | Cercocebus atys | 35.1 | 8e-18 | 89.7 |
| LLPS-Aon-4160 | Aotus nancymaae | 35.1 | 7e-18 | 90.1 |
| LLPS-Caj-0086 | Callithrix jacchus | 35.1 | 6e-17 | 87.4 |
| LLPS-Paa-2665 | Papio anubis | 35.1 | 9e-18 | 89.7 |
| LLPS-Mal-4703 | Mandrillus leucophaeus | 35.1 | 8e-18 | 90.1 |
| LLPS-Otg-4546 | Otolemur garnettii | 35.06 | 2e-18 | 91.7 |
| LLPS-Ran-2400 | Rattus norvegicus | 35.06 | 1e-17 | 90.1 |
| LLPS-Nef-1200 | Neosartorya fischeri | 35.04 | 5e-21 | 100 |
| LLPS-Ved-1349 | Verticillium dahliae | 34.78 | 1e-19 | 96.7 |
| LLPS-Gaa-0159 | Gasterosteus aculeatus | 34.78 | 2e-20 | 97.4 |
| LLPS-Lac-3666 | Latimeria chalumnae | 34.72 | 9e-17 | 86.7 |
| LLPS-Asfu-0525 | Aspergillus fumigatus | 34.62 | 1e-20 | 99.8 |
| LLPS-Asc-1574 | Aspergillus clavatus | 34.6 | 1e-23 | 108 |
| LLPS-Asni-1421 | Aspergillus niger | 34.56 | 7e-20 | 97.1 |
| LLPS-Fud-1910 | Fukomys damarensis | 34.46 | 4e-17 | 88.2 |
| LLPS-Pat-1945 | Pan troglodytes | 34.44 | 5e-17 | 87.4 |
| LLPS-Pap-4653 | Pan paniscus | 34.44 | 5e-17 | 87.4 |
| LLPS-Eqc-3795 | Equus caballus | 34.44 | 2e-15 | 83.6 |
| LLPS-Gog-2838 | Gorilla gorilla | 34.44 | 5e-17 | 87.4 |
| LLPS-Abg-1557 | Absidia glauca | 34.41 | 4e-26 | 114 |
| LLPS-Cog-1202 | Colletotrichum gloeosporioides | 34.19 | 4e-20 | 98.2 |
| LLPS-Pof-3379 | Poecilia formosa | 34.18 | 4e-21 | 99.8 |
| LLPS-Trv-1505 | Trichoderma virens | 34.06 | 7e-23 | 106 |
| LLPS-Beb-1516 | Beauveria bassiana | 33.89 | 3e-23 | 107 |
| LLPS-Mum-4648 | Mus musculus | 33.77 | 6e-17 | 87.8 |
| LLPS-Ast-0784 | Aspergillus terreus | 33.76 | 1e-22 | 105 |
| LLPS-Nol-4184 | Nomascus leucogenys | 33.58 | 2e-14 | 79.7 |
| LLPS-Drm-1259 | Drosophila melanogaster | 33.5 | 7e-18 | 90.1 |
| LLPS-Fus-0166 | Fusarium solani | 33.19 | 6e-22 | 103 |
| LLPS-Ten-2336 | Tetraodon nigroviridis | 33.17 | 6e-20 | 95.9 |
| LLPS-Cogr-0632 | Colletotrichum graminicola | 33.05 | 2e-19 | 95.9 |
| LLPS-Pyt-0111 | Pyrenophora teres | 33.04 | 1e-20 | 99.4 |
| LLPS-Dar-4114 | Danio rerio | 32.98 | 7e-19 | 93.2 |
| LLPS-Mel-0681 | Melampsora laricipopulina | 32.98 | 1e-19 | 94.0 |
| LLPS-Asm-1398 | Astyanax mexicanus | 32.53 | 3e-23 | 106 |
| LLPS-Gag-1198 | Gaeumannomyces graminis | 32.52 | 7e-19 | 94.4 |
| LLPS-Zyt-0813 | Zymoseptoria tritici | 32.14 | 6e-11 | 68.9 |
| LLPS-Scm-3423 | Scophthalmus maximus | 32.07 | 3e-18 | 91.3 |
| LLPS-Blg-0801 | Blumeria graminis | 31.97 | 5e-22 | 103 |
| LLPS-Tra-2338 | Triticum aestivum | 31.2 | 6e-17 | 87.4 |
| LLPS-Pes-2348 | Pelodiscus sinensis | 31.15 | 2e-15 | 82.8 |
| LLPS-Lem-1090 | Leptosphaeria maculans | 31.08 | 4e-21 | 100 |
| LLPS-Sem-2387 | Selaginella moellendorffii | 31.06 | 3e-19 | 95.1 |
| LLPS-Asf-0834 | Aspergillus flavus | 30.91 | 2e-23 | 106 |
| LLPS-Zem-2308 | Zea mays | 30.84 | 2e-15 | 82.8 |
| LLPS-Scj-1182 | Schizosaccharomyces japonicus | 30.77 | 9e-24 | 108 |
| LLPS-Put-0243 | Puccinia triticina | 30.7 | 5e-26 | 116 |
| LLPS-Php-1580 | Physcomitrella patens | 30.7 | 9e-19 | 93.2 |
| LLPS-Mao-0070 | Magnaporthe oryzae | 30.67 | 5e-17 | 88.6 |
| LLPS-Sob-0356 | Sorghum bicolor | 30.17 | 2e-15 | 82.4 |
| LLPS-Gor-2456 | Gossypium raimondii | 30.13 | 3e-15 | 82.4 |
| LLPS-Glm-2703 | Glycine max | 30.08 | 1e-18 | 92.4 |
| LLPS-Aso-1446 | Aspergillus oryzae | 29.91 | 7e-25 | 112 |
| LLPS-Scc-1370 | Schizosaccharomyces cryophilus | 29.75 | 2e-23 | 106 |
| LLPS-Met-1329 | Medicago truncatula | 29.74 | 8e-15 | 80.9 |
| LLPS-Hov-1987 | Hordeum vulgare | 29.74 | 2e-15 | 82.8 |
| LLPS-Vir-1458 | Vigna radiata | 29.66 | 5e-14 | 79.3 |
| LLPS-Cae-1864 | Caenorhabditis elegans | 29.58 | 5e-10 | 65.9 |
| LLPS-Nia-1595 | Nicotiana attenuata | 29.18 | 1e-15 | 83.6 |
| LLPS-Sol-0395 | Solanum lycopersicum | 29.17 | 3e-15 | 82.4 |
| LLPS-Scp-1597 | Schizosaccharomyces pombe | 29.01 | 6e-23 | 105 |
| LLPS-Sot-1802 | Solanum tuberosum | 28.45 | 6e-15 | 81.3 |
| LLPS-Viv-2345 | Vitis vinifera | 28.02 | 1e-13 | 77.4 |
| LLPS-Phv-2396 | Phaseolus vulgaris | 27.78 | 5e-13 | 75.5 |
| LLPS-Arl-2750 | Arabidopsis lyrata | 27.66 | 3e-13 | 76.3 |
| LLPS-Brr-1520 | Brassica rapa | 27.12 | 7e-13 | 75.1 |
| LLPS-Osl-0911 | Ostreococcus lucimarinus | 26.92 | 8e-09 | 62.0 |
| LLPS-Art-2098 | Arabidopsis thaliana | 26.38 | 1e-12 | 74.3 |
| LLPS-Chc-0739 | Chondrus crispus | 26.32 | 6e-10 | 63.9 |
| LLPS-Bro-2116 | Brassica oleracea | 26.0 | 5e-10 | 65.9 |