DrLLPS - Data resource of LLPS

LLPS-Cog-0742
CGGC5_4966

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
Gene Name:	CGGC5_4966
Ensembl Gene:	CGGC5_4966
Ensembl Protein:	ELA35288
Organism:	Colletotrichum gloeosporioides
Taxa ID:	1213859
LLPS Type:	Others

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Stress granule, Others	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Homo sapiens	LLPS-Hos-1291	P04843	Client	Stress granule, Postsynaptic density	30.40	2e-45	172

▼ FUNCTION

Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	ELA35288	ELA35288
UniProt		L2GB81, L2GB81_COLFN
GeneBank	KB020576	ELA35288.1
RefSeq	XM_007275616.1	XP_007275678.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MRAFAIAAGL LSLLSPVVAS SAAADKSEVN QPSTFKPPQV FKNANLVHII SLEKNYVKES 60 61 INVLIENIDK QPQDEYYLPF TPDQMSRVGG FEAKDRKDPE AGPFAVDAVE FDPSSEIQYY 120 121 KIKLPAPLKA DGQQTLSISY YLLKAYKPLP AAIAQEENQF LAYDFSVYAP SAYVTTKQKT 180 181 ELKSHSSNIP DYTKLPGSGD IKEFPQKAGS KLTYGPFDEK PAGAVSKAQV RFEFTKPVTH 240 241 VSKLDRDIEV SHWGGNVAFE ERYELYHRGA NLSKLFNRVK WQQSQYFNPN TYALKELRFP 300 301 LKVGSADAYF TDAIGNVSTS RFRSNKREAL LEIKPRYPVF GGWKYPFTIG WNSDAKNFVR 360 361 TVEAGKYVVN VPFLEGPKQP EGIEYGQVNL RILLPEGATN VKFYTSIPQS AIADSAVGVH 420 421 QTYLDTVGRT SVTLKAQNLV DEFRDREVIV TYDYSVASAL RKPLIVFASM VFVFVAAWVV 480 481 GGLNPTIAKK K 491

Protein Sequence (FASTA)

1     MRAFAIAAGL  LSLLSPVVAS  SAAADKSEVN  QPSTFKPPQV  FKNANLVHII  SLEKNYVKES  60
61    INVLIENIDK  QPQDEYYLPF  TPDQMSRVGG  FEAKDRKDPE  AGPFAVDAVE  FDPSSEIQYY  120
121   KIKLPAPLKA  DGQQTLSISY  YLLKAYKPLP  AAIAQEENQF  LAYDFSVYAP  SAYVTTKQKT  180
181   ELKSHSSNIP  DYTKLPGSGD  IKEFPQKAGS  KLTYGPFDEK  PAGAVSKAQV  RFEFTKPVTH  240
241   VSKLDRDIEV  SHWGGNVAFE  ERYELYHRGA  NLSKLFNRVK  WQQSQYFNPN  TYALKELRFP  300
301   LKVGSADAYF  TDAIGNVSTS  RFRSNKREAL  LEIKPRYPVF  GGWKYPFTIG  WNSDAKNFVR  360
361   TVEAGKYVVN  VPFLEGPKQP  EGIEYGQVNL  RILLPEGATN  VKFYTSIPQS  AIADSAVGVH  420
421   QTYLDTVGRT  SVTLKAQNLV  DEFRDREVIV  TYDYSVASAL  RKPLIVFASM  VFVFVAAWVV  480
481   GGLNPTIAKK  K  491

▼ KEYWORD

ID	Family
KW-0181	Complete proteome
KW-0256	Endoplasmic reticulum
KW-0472	Membrane
KW-1185	Reference proteome
KW-0732	Signal
KW-0808	Transferase
KW-0812	Transmembrane
KW-1133	Transmembrane helix

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0005789	Cellular Component	Endoplasmic reticulum membrane
GO:0016021	Cellular Component	Integral component of membrane
GO:0004579	Molecular Function	Dolichyl-diphosphooligosaccharide-protein glycotransferase activity
GO:0006486	Biological Process	Protein glycosylation

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Coo-1405	Colletotrichum orbiculare	87.53	0.0	823
LLPS-Cogr-1080	Colletotrichum graminicola	83.19	0.0	799
LLPS-Ved-1147	Verticillium dahliae	74.54	0.0	726
LLPS-Fus-0581	Fusarium solani	70.98	0.0	691
LLPS-Nec-1253	Neurospora crassa	70.84	0.0	679
LLPS-Mao-1562	Magnaporthe oryzae	70.62	0.0	667
LLPS-Beb-0455	Beauveria bassiana	69.86	0.0	653
LLPS-Map-0118	Magnaporthe poae	68.25	0.0	649
LLPS-Gag-1506	Gaeumannomyces graminis	67.53	0.0	649
LLPS-Trr-1588	Trichoderma reesei	66.97	0.0	637
LLPS-Trv-0707	Trichoderma virens	65.38	0.0	616
LLPS-Fuv-0686	Fusarium verticillioides	64.35	0.0	625
LLPS-Scs-0901	Sclerotinia sclerotiorum	60.17	0.0	559
LLPS-Dos-1283	Dothistroma septosporum	56.68	4e-180	522
LLPS-Fuo-1261	Fusarium oxysporum	56.5	3e-179	519
LLPS-Pyt-1539	Pyrenophora teres	54.64	3e-175	509
LLPS-Pytr-0743	Pyrenophora triticirepentis	54.64	2e-168	492
LLPS-Zyt-1266	Zymoseptoria tritici	54.0	4e-168	491
LLPS-Phn-1522	Phaeosphaeria nodorum	53.13	4e-174	506
LLPS-Lem-1253	Leptosphaeria maculans	52.92	6e-172	501
LLPS-Blg-1557	Blumeria graminis	50.45	2e-162	479
LLPS-Asn-1462	Aspergillus nidulans	49.55	6e-147	437
LLPS-Asni-1533	Aspergillus niger	49.37	1e-138	416
LLPS-Ast-1048	Aspergillus terreus	49.14	4e-150	445
LLPS-Aso-1328	Aspergillus oryzae	48.55	5e-144	430
LLPS-Asf-1125	Aspergillus flavus	48.55	5e-144	430
LLPS-Asfu-0780	Aspergillus fumigatus	48.12	6e-146	435
LLPS-Asc-0017	Aspergillus clavatus	47.49	2e-146	436
LLPS-Nef-1269	Neosartorya fischeri	46.83	3e-138	415
LLPS-Tum-1273	Tuber melanosporum	45.95	5e-130	393
LLPS-Abg-1264	Absidia glauca	43.48	7e-56	193
LLPS-Yal-0849	Yarrowia lipolytica	32.86	3e-59	208
LLPS-Crn-0929	Cryptococcus neoformans	32.6	5e-53	192
LLPS-Arl-1117	Arabidopsis lyrata	32.39	3e-37	148
LLPS-Art-0536	Arabidopsis thaliana	31.82	7e-37	147
LLPS-Chr-1448	Chlamydomonas reinhardtii	31.79	1e-45	173
LLPS-Mod-1022	Monodelphis domestica	31.5	4e-45	172
LLPS-Dac-0021	Daucus carota	31.41	4e-40	157
LLPS-Otg-1428	Otolemur garnettii	31.32	6e-45	171
LLPS-Usm-0219	Ustilago maydis	31.27	1e-38	152
LLPS-Brn-2746	Brassica napus	31.25	9e-38	150
LLPS-Bro-1350	Brassica oleracea	31.25	9e-38	150
LLPS-Mal-3537	Mandrillus leucophaeus	31.22	5e-30	124
LLPS-Cas-3098	Carlito syrichta	31.22	3e-30	125
LLPS-Scj-0533	Schizosaccharomyces japonicus	31.12	7e-56	199
LLPS-Sol-1009	Solanum lycopersicum	31.12	6e-49	181
LLPS-Anc-3055	Anolis carolinensis	31.03	5e-47	177
LLPS-Spr-0368	Sporisorium reilianum	30.79	1e-41	160
LLPS-Ora-0057	Ornithorhynchus anatinus	30.77	5e-18	89.0
LLPS-Pes-0990	Pelodiscus sinensis	30.75	1e-45	172
LLPS-Brr-0245	Brassica rapa	30.68	2e-37	149
LLPS-Prp-1684	Prunus persica	30.56	7e-39	153
LLPS-Vir-0090	Vigna radiata	30.52	1e-49	183
LLPS-Tag-0725	Taeniopygia guttata	30.46	5e-47	176
LLPS-Fia-0374	Ficedula albicollis	30.46	1e-46	176
LLPS-Php-0376	Physcomitrella patens	30.42	3e-45	172
LLPS-Icp-0139	Ictalurus punctatus	30.26	2e-44	170
LLPS-Mup-3450	Mustela putorius furo	30.17	3e-44	169
LLPS-Myl-4035	Myotis lucifugus	30.17	7e-44	168
LLPS-Caf-0051	Canis familiaris	30.17	3e-44	169
LLPS-Gaga-2017	Gallus gallus	30.17	3e-45	172
LLPS-Nol-1156	Nomascus leucogenys	30.17	2e-44	169
LLPS-Pap-1556	Pan paniscus	30.17	1e-44	170
LLPS-Dar-0592	Danio rerio	30.17	2e-44	170
LLPS-Meg-1815	Meleagris gallopavo	30.17	2e-46	174
LLPS-Fec-3269	Felis catus	30.17	2e-44	169
LLPS-Man-0989	Macaca nemestrina	30.17	3e-44	169
LLPS-Anp-1575	Anas platyrhynchos	30.17	9e-46	173
LLPS-Loa-3398	Loxodonta africana	30.17	8e-44	168
LLPS-Orc-4031	Oryctolagus cuniculus	30.17	3e-44	169
LLPS-Bot-3444	Bos taurus	29.89	1e-42	164
LLPS-Aim-2958	Ailuropoda melanoleuca	29.89	9e-44	167
LLPS-Fud-2682	Fukomys damarensis	29.89	1e-43	167
LLPS-Poa-1009	Pongo abelii	29.89	2e-44	169
LLPS-Cap-3127	Cavia porcellus	29.89	8e-44	168
LLPS-Orn-1488	Oreochromis niloticus	29.89	3e-43	166
LLPS-Sot-2013	Solanum tuberosum	29.88	7e-41	159
LLPS-Thc-1903	Theobroma cacao	29.88	3e-41	160
LLPS-Aon-4087	Aotus nancymaae	29.81	7e-42	162
LLPS-Mel-0771	Melampsora laricipopulina	29.81	4e-36	144
LLPS-Mae-0897	Manihot esculenta	29.8	2e-34	140
LLPS-Sem-0306	Selaginella moellendorffii	29.77	8e-46	174
LLPS-Nia-0935	Nicotiana attenuata	29.72	3e-41	160
LLPS-Eqc-2088	Equus caballus	29.6	3e-43	166
LLPS-Lac-1608	Latimeria chalumnae	29.6	2e-44	169
LLPS-Mea-4314	Mesocricetus auratus	29.59	2e-45	172
LLPS-Scc-1262	Schizosaccharomyces cryophilus	29.59	2e-53	192
LLPS-Cis-1651	Ciona savignyi	29.57	5e-46	174
LLPS-Cus-2286	Cucumis sativus	29.48	6e-38	150
LLPS-Met-0203	Medicago truncatula	29.48	1e-38	152
LLPS-Sac-1420	Saccharomyces cerevisiae	29.46	1e-50	185
LLPS-Gor-0026	Gossypium raimondii	29.41	2e-41	160
LLPS-Caj-1780	Callithrix jacchus	29.34	2e-44	169
LLPS-Ova-1052	Ovis aries	29.31	2e-41	160
LLPS-Sus-1378	Sus scrofa	29.31	5e-42	163
LLPS-Urm-0141	Ursus maritimus	29.31	5e-43	165
LLPS-Pot-1743	Populus trichocarpa	29.31	3e-38	151
LLPS-Phv-2265	Phaseolus vulgaris	29.31	1e-41	161
LLPS-Via-1547	Vigna angularis	29.2	2e-36	145
LLPS-Hea-1498	Helianthus annuus	29.15	8e-41	159
LLPS-Asg-1243	Ashbya gossypii	29.11	1e-40	157
LLPS-Mum-4056	Mus musculus	28.9	2e-44	169
LLPS-Drm-0499	Drosophila melanogaster	28.84	1e-43	166
LLPS-Glm-1448	Glycine max	28.84	8e-41	159
LLPS-Ran-1204	Rattus norvegicus	28.83	1e-43	167
LLPS-Zem-1214	Zea mays	28.67	6e-41	159
LLPS-Mua-0181	Musa acuminata	28.64	5e-45	171
LLPS-Coc-1176	Corchorus capsularis	28.64	2e-37	149
LLPS-Kop-0887	Komagataella pastoris	28.57	6e-39	152
LLPS-Scp-0812	Schizosaccharomyces pombe	28.54	4e-48	178
LLPS-Asm-2653	Astyanax mexicanus	28.4	4e-45	171
LLPS-Cii-1298	Ciona intestinalis	28.37	2e-45	170
LLPS-Cae-1532	Caenorhabditis elegans	28.37	2e-43	166
LLPS-Gaa-2647	Gasterosteus aculeatus	28.3	3e-45	172
LLPS-Viv-2037	Vitis vinifera	27.96	2e-39	154
LLPS-Sah-3080	Sarcophilus harrisii	27.92	6e-40	156
LLPS-Leo-2009	Lepisosteus oculatus	27.91	9e-48	178
LLPS-Xet-0497	Xenopus tropicalis	27.87	7e-45	171
LLPS-Sei-0800	Setaria italica	27.86	8e-41	160
LLPS-Brd-0070	Brachypodium distachyon	27.86	9e-41	159
LLPS-Rhb-1358	Rhinopithecus bieti	27.85	1e-44	170
LLPS-Ten-2170	Tetraodon nigroviridis	27.83	2e-45	172
LLPS-Scm-2478	Scophthalmus maximus	27.74	5e-46	174
LLPS-Pug-0323	Puccinia graminis	27.68	2e-43	166
LLPS-Put-0557	Puccinia triticina	27.67	7e-39	152
LLPS-Paa-0624	Papio anubis	27.63	3e-44	169
LLPS-Maf-1094	Macaca fascicularis	27.63	3e-44	169
LLPS-Chs-0180	Chlorocebus sabaeus	27.63	4e-44	169
LLPS-Cea-0408	Cercocebus atys	27.63	4e-44	169
LLPS-Mam-3995	Macaca mulatta	27.63	3e-44	169
LLPS-Pat-1433	Pan troglodytes	27.63	2e-44	170
LLPS-Hos-1291	Homo sapiens	27.63	2e-44	169
LLPS-Orb-0983	Oryza barthii	27.62	6e-40	156
LLPS-Ori-0202	Oryza indica	27.62	3e-40	157
LLPS-Orni-0384	Oryza nivara	27.62	6e-40	156
LLPS-Orm-1048	Oryza meridionalis	27.62	1e-39	155
LLPS-Orr-1232	Oryza rufipogon	27.62	3e-40	157
LLPS-Org-0742	Oryza glaberrima	27.62	6e-40	156
LLPS-Ors-1703	Oryza sativa	27.62	3e-40	157
LLPS-Orp-0712	Oryza punctata	27.62	5e-40	156
LLPS-Sob-2395	Sorghum bicolor	27.62	5e-39	154
LLPS-Orgl-0380	Oryza glumaepatula	27.38	4e-40	155
LLPS-Orbr-0396	Oryza brachyantha	27.38	1e-38	152
LLPS-Tar-3389	Takifugu rubripes	27.36	7e-45	171
LLPS-Orl-0732	Oryzias latipes	27.34	4e-43	166
LLPS-Gog-1870	Gorilla gorilla	27.23	2e-41	160
LLPS-Scf-0792	Scleropages formosus	27.21	4e-45	171
LLPS-Pof-0429	Poecilia formosa	27.17	7e-43	165
LLPS-Xim-0128	Xiphophorus maculatus	27.0	8e-43	165
LLPS-Lep-0771	Leersia perrieri	26.9	1e-38	152
LLPS-Hov-0598	Hordeum vulgare	26.9	1e-35	144
LLPS-Tra-0918	Triticum aestivum	26.9	3e-37	148
LLPS-Amt-0753	Amborella trichopoda	26.6	5e-35	142
LLPS-Dio-3263	Dipodomys ordii	26.07	2e-25	113
LLPS-Miv-0966	Microbotryum violaceum	25.53	5e-28	120
LLPS-Gas-1317	Galdieria sulphuraria	25.24	5e-27	118
LLPS-Tru-0058	Triticum urartu	24.76	3e-32	133

LLPS-Cog-0742CGGC5_4966

Protein Sequence

Nucleotide Sequence

LLPS-Cog-0742
CGGC5_4966