LLPS-Asni-1533
ostA
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 |
| Gene Name: | ostA, An02g14560 |
| Ensembl Gene: | An02g14560 |
| Ensembl Protein: | CAK48885 |
| Organism: | Aspergillus niger |
| Taxa ID: | 425011 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Stress granule, Others | Predicted from orthologs | (View) |
▼ FUNCTION
| Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | CAK48885 | CAK48885 |
| UniProt | A2QFH4, A2QFH4_ASPNC | |
| GeneBank | AM270040 | CAK48885.1 |
| RefSeq | XM_001400548.2 | XP_001400585.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MRPFTALAAL CGLFLSSNSL VYADSAPSSS PVALPRDFKP PQVFKNANLV RNTNLEKGYL 60 61 RETVNVVVEN VDKKPQSDYY LSFPSDLYDK VGALEVRDKS APEQGRFEVE ATEFDSSRDF 120 121 QYFVVHLPKP LAPSSQITLG ISYSALNTLK PRPAAISQND RQYLAYAFSA YAPSAYTTTT 180 181 QKTKIKFPST NVPDYTSTDL TSGADPERQG ATYTYGPYAD VAPETTYPAS VRYEFTKPVI 240 241 TATLLERDLE VSHWGGNLAT EERYWLRNNG SKLTDNFNRV EWTISSYQQL PSSAIRELKI 300 301 PLKPGSVDPY FTDDIGNVST SRYRPGKVPN RDASLELRPR FPIFGGWNYS FRIGWNNDLS 360 361 AFLRKAVTGA DSYVLKVPFI EGPKVSEGIQ YEKAVVRIIL PEGARNVRYE LLEKATSNGL 420 421 PGANQIQTEL TSHKTFMDTL GRTALTLTVE ELTDEARDSQ IVVTYDYSLW DGLRKPVTIT 480 481 AGLFTVFVAA WAIGNIDVSI KKR 503 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGAGGCCGT TTACCGCACT TGCTGCGCTG TGCGGCTTGT TCCTGTCCAG CAACAGCTTG 60 61 GTCTATGCCG ACTCGGCTCC CTCGAGCTCC CCTGTAGCTC TCCCTCGCGA TTTCAAGCCT 120 121 CCCCAAGTGT TTAAGAACGC CAATCTTGTC CGCAACACCA ATTTGGAGAA GGGATACCTA 180 181 CGTGAGACCG TCAATGTTGT CGTTGAGAAT GTGGACAAGA AGCCGCAGTC CGACTACTAC 240 241 TTGTCCTTCC CATCCGACCT TTACGACAAG GTCGGTGCCC TAGAAGTCCG TGATAAATCG 300 301 GCTCCTGAAC AGGGACGCTT CGAAGTGGAA GCTACTGAGT TCGACTCAAG CAGGGACTTC 360 361 CAGTACTTCG TTGTTCACCT CCCCAAGCCT CTCGCCCCTT CGTCGCAGAT CACTCTGGGC 420 421 ATCTCCTACT CCGCCCTCAA CACCCTGAAG CCCCGTCCTG CGGCCATCAG CCAGAATGAT 480 481 CGCCAGTACC TCGCCTATGC CTTCTCTGCC TACGCTCCCT CGGCTTACAC GACAACGACC 540 541 CAGAAGACCA AGATCAAGTT CCCCAGCACC AATGTTCCCG ACTACACCTC CACGGACCTG 600 601 ACGTCGGGCG CGGATCCAGA GCGCCAGGGT GCCACCTACA CCTACGGACC CTACGCCGAC 660 661 GTCGCTCCCG AGACCACCTA CCCGGCCAGT GTCCGGTACG AGTTCACCAA GCCCGTCATC 720 721 ACTGCCACTC TTCTGGAGCG TGACCTGGAA GTGTCCCACT GGGGCGGCAA CCTGGCGACG 780 781 GAAGAGCGCT ACTGGCTGCG CAACAACGGC TCCAAGCTCA CCGACAACTT CAACCGCGTG 840 841 GAATGGACCA TCAGCAGCTA CCAGCAGCTG CCGTCCTCCG CTATCCGCGA GCTGAAGATC 900 901 CCCCTCAAGC CCGGCTCCGT GGACCCCTAC TTCACCGACG ACATTGGCAA CGTTTCCACG 960 961 AGCCGCTACC GTCCCGGAAA GGTCCCGAAC CGTGACGCCT CCCTGGAGCT TCGTCCCCGG 1020 1021 TTCCCCATCT TCGGCGGATG GAACTACAGC TTCCGCATTG GCTGGAACAA CGACCTCTCT 1080 1081 GCCTTCCTTC GCAAGGCTGT CACCGGCGCT GATTCCTACG TCCTCAAGGT CCCCTTCATC 1140 1141 GAGGGCCCCA AGGTTTCCGA GGGTATTCAG TATGAGAAGG CCGTCGTGCG CATCATCCTC 1200 1201 CCCGAGGGTG CCCGGAACGT CCGCTACGAG CTCCTCGAGA AGGCGACTAG CAATGGTCTC 1260 1261 CCCGGTGCGA ACCAGATCCA GACTGAGCTC ACCAGCCACA AGACTTTCAT GGATACCCTA 1320 1321 GGACGCACGG CGCTGACTTT GACCGTGGAG GAGTTGACTG ATGAGGCCCG TGACTCGCAG 1380 1381 ATAGTGGTCA CTTACGACTA CTCTCTGTGG GATGGATTGC GCAAGCCCGT GACCATCACG 1440 1441 GCGGGGCTGT TCACCGTGTT TGTTGCCGCG TGGGCGATTG GAAATATTGA CGTGAGTATT 1500 1501 AAGAAGCGGT AG 1512 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Endoplasmic reticulum membrane | |
Cellular Component | Integral component of membrane | |
Molecular Function | Dolichyl-diphosphooligosaccharide-protein glycotransferase activity | |
Biological Process | Protein glycosylation |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Nef-1269 | Neosartorya fischeri | 77.47 | 0.0 | 736 |
| LLPS-Asfu-0780 | Aspergillus fumigatus | 77.08 | 0.0 | 755 |
| LLPS-Asc-0017 | Aspergillus clavatus | 75.49 | 0.0 | 754 |
| LLPS-Asf-1125 | Aspergillus flavus | 73.91 | 0.0 | 724 |
| LLPS-Aso-1328 | Aspergillus oryzae | 73.91 | 0.0 | 724 |
| LLPS-Asn-1462 | Aspergillus nidulans | 73.72 | 0.0 | 740 |
| LLPS-Ast-1048 | Aspergillus terreus | 72.02 | 0.0 | 728 |
| LLPS-Pytr-0743 | Pyrenophora triticirepentis | 55.88 | 6e-180 | 522 |
| LLPS-Pyt-1539 | Pyrenophora teres | 55.1 | 0.0 | 536 |
| LLPS-Lem-1253 | Leptosphaeria maculans | 54.56 | 0.0 | 530 |
| LLPS-Phn-1522 | Phaeosphaeria nodorum | 52.88 | 7e-175 | 509 |
| LLPS-Scs-0901 | Sclerotinia sclerotiorum | 52.28 | 5e-166 | 486 |
| LLPS-Dos-1283 | Dothistroma septosporum | 51.02 | 1e-162 | 478 |
| LLPS-Zyt-1266 | Zymoseptoria tritici | 50.91 | 5e-162 | 476 |
| LLPS-Ved-1147 | Verticillium dahliae | 50.43 | 8e-145 | 432 |
| LLPS-Gag-1506 | Gaeumannomyces graminis | 48.74 | 1e-151 | 449 |
| LLPS-Nec-1253 | Neurospora crassa | 48.64 | 2e-146 | 437 |
| LLPS-Map-0118 | Magnaporthe poae | 48.31 | 1e-149 | 444 |
| LLPS-Cog-0742 | Colletotrichum gloeosporioides | 48.13 | 2e-144 | 431 |
| LLPS-Coo-1405 | Colletotrichum orbiculare | 48.01 | 3e-152 | 451 |
| LLPS-Blg-1557 | Blumeria graminis | 47.27 | 2e-142 | 428 |
| LLPS-Mao-1562 | Magnaporthe oryzae | 47.09 | 4e-147 | 437 |
| LLPS-Cogr-1080 | Colletotrichum graminicola | 46.17 | 4e-141 | 423 |
| LLPS-Trr-1588 | Trichoderma reesei | 46.03 | 8e-148 | 439 |
| LLPS-Beb-0455 | Beauveria bassiana | 46.03 | 1e-146 | 436 |
| LLPS-Fuv-0686 | Fusarium verticillioides | 45.7 | 1e-142 | 426 |
| LLPS-Fus-0581 | Fusarium solani | 45.18 | 3e-141 | 422 |
| LLPS-Trv-0707 | Trichoderma virens | 44.58 | 2e-141 | 423 |
| LLPS-Fuo-1261 | Fusarium oxysporum | 42.97 | 4e-116 | 358 |
| LLPS-Tum-1273 | Tuber melanosporum | 42.57 | 2e-125 | 382 |
| LLPS-Abg-1264 | Absidia glauca | 42.34 | 4e-51 | 181 |
| LLPS-Cas-3098 | Carlito syrichta | 33.69 | 2e-31 | 129 |
| LLPS-Mal-3537 | Mandrillus leucophaeus | 32.97 | 7e-31 | 127 |
| LLPS-Anc-3055 | Anolis carolinensis | 32.9 | 4e-46 | 175 |
| LLPS-Pes-0990 | Pelodiscus sinensis | 32.9 | 1e-46 | 175 |
| LLPS-Meg-1815 | Meleagris gallopavo | 32.39 | 6e-47 | 176 |
| LLPS-Anp-1575 | Anas platyrhynchos | 32.13 | 3e-46 | 175 |
| LLPS-Tag-0725 | Taeniopygia guttata | 32.01 | 4e-47 | 176 |
| LLPS-Man-0989 | Macaca nemestrina | 31.98 | 5e-43 | 166 |
| LLPS-Cap-3127 | Cavia porcellus | 31.95 | 3e-42 | 163 |
| LLPS-Spr-0368 | Sporisorium reilianum | 31.91 | 2e-42 | 162 |
| LLPS-Poa-1009 | Pongo abelii | 31.88 | 2e-42 | 163 |
| LLPS-Lac-1608 | Latimeria chalumnae | 31.88 | 3e-44 | 169 |
| LLPS-Yal-0849 | Yarrowia lipolytica | 31.83 | 1e-60 | 212 |
| LLPS-Gaga-2017 | Gallus gallus | 31.76 | 7e-46 | 174 |
| LLPS-Fia-0374 | Ficedula albicollis | 31.76 | 2e-46 | 176 |
| LLPS-Ora-0057 | Ornithorhynchus anatinus | 31.67 | 2e-20 | 96.7 |
| LLPS-Pap-1556 | Pan paniscus | 31.45 | 5e-43 | 165 |
| LLPS-Urm-0141 | Ursus maritimus | 31.2 | 9e-43 | 164 |
| LLPS-Asm-2653 | Astyanax mexicanus | 31.09 | 9e-43 | 165 |
| LLPS-Usm-0219 | Ustilago maydis | 31.02 | 2e-37 | 148 |
| LLPS-Dar-0592 | Danio rerio | 30.89 | 4e-43 | 166 |
| LLPS-Cii-1298 | Ciona intestinalis | 30.47 | 2e-40 | 156 |
| LLPS-Kop-0887 | Komagataella pastoris | 30.26 | 1e-45 | 171 |
| LLPS-Myl-4035 | Myotis lucifugus | 30.24 | 5e-44 | 169 |
| LLPS-Icp-0139 | Ictalurus punctatus | 30.21 | 2e-40 | 158 |
| LLPS-Aon-4087 | Aotus nancymaae | 30.17 | 9e-41 | 159 |
| LLPS-Loa-3398 | Loxodonta africana | 30.17 | 1e-44 | 170 |
| LLPS-Mod-1022 | Monodelphis domestica | 30.17 | 2e-44 | 170 |
| LLPS-Caj-1780 | Callithrix jacchus | 30.13 | 5e-45 | 171 |
| LLPS-Mua-0181 | Musa acuminata | 30.04 | 1e-38 | 152 |
| LLPS-Sol-0263 | Solanum lycopersicum | 30.03 | 1e-25 | 115 |
| LLPS-Sem-0306 | Selaginella moellendorffii | 29.98 | 4e-47 | 177 |
| LLPS-Paa-0624 | Papio anubis | 29.96 | 5e-45 | 172 |
| LLPS-Cea-0408 | Cercocebus atys | 29.96 | 4e-45 | 172 |
| LLPS-Chs-0180 | Chlorocebus sabaeus | 29.96 | 4e-45 | 172 |
| LLPS-Maf-1094 | Macaca fascicularis | 29.96 | 5e-45 | 172 |
| LLPS-Mum-4056 | Mus musculus | 29.96 | 2e-44 | 170 |
| LLPS-Mam-3995 | Macaca mulatta | 29.96 | 5e-45 | 172 |
| LLPS-Eqc-2088 | Equus caballus | 29.96 | 1e-43 | 167 |
| LLPS-Rhb-1358 | Rhinopithecus bieti | 29.96 | 3e-45 | 172 |
| LLPS-Hos-1291 | Homo sapiens | 29.96 | 2e-44 | 170 |
| LLPS-Pat-1433 | Pan troglodytes | 29.96 | 1e-44 | 171 |
| LLPS-Tra-0918 | Triticum aestivum | 29.85 | 2e-40 | 158 |
| LLPS-Otg-1428 | Otolemur garnettii | 29.85 | 5e-44 | 169 |
| LLPS-Mea-4314 | Mesocricetus auratus | 29.79 | 1e-44 | 171 |
| LLPS-Nol-1156 | Nomascus leucogenys | 29.71 | 6e-45 | 171 |
| LLPS-Xet-0497 | Xenopus tropicalis | 29.7 | 2e-46 | 176 |
| LLPS-Orc-4031 | Oryctolagus cuniculus | 29.64 | 6e-45 | 171 |
| LLPS-Sah-3080 | Sarcophilus harrisii | 29.63 | 7e-40 | 156 |
| LLPS-Brd-0070 | Brachypodium distachyon | 29.61 | 3e-40 | 157 |
| LLPS-Mae-0897 | Manihot esculenta | 29.59 | 3e-40 | 157 |
| LLPS-Ran-1204 | Rattus norvegicus | 29.54 | 9e-44 | 168 |
| LLPS-Cae-1532 | Caenorhabditis elegans | 29.49 | 8e-37 | 147 |
| LLPS-Fec-3269 | Felis catus | 29.49 | 2e-43 | 167 |
| LLPS-Crn-0929 | Cryptococcus neoformans | 29.47 | 5e-44 | 167 |
| LLPS-Thc-1903 | Theobroma cacao | 29.44 | 8e-37 | 147 |
| LLPS-Hov-0598 | Hordeum vulgare | 29.39 | 5e-40 | 157 |
| LLPS-Orp-0712 | Oryza punctata | 29.39 | 2e-38 | 152 |
| LLPS-Scc-1262 | Schizosaccharomyces cryophilus | 29.32 | 2e-44 | 167 |
| LLPS-Mup-3450 | Mustela putorius furo | 29.3 | 1e-43 | 167 |
| LLPS-Sus-1378 | Sus scrofa | 29.28 | 2e-44 | 170 |
| LLPS-Cis-1651 | Ciona savignyi | 29.28 | 3e-43 | 166 |
| LLPS-Aim-2958 | Ailuropoda melanoleuca | 29.27 | 3e-43 | 166 |
| LLPS-Scj-0533 | Schizosaccharomyces japonicus | 29.27 | 1e-46 | 174 |
| LLPS-Caf-0051 | Canis familiaris | 29.27 | 2e-43 | 167 |
| LLPS-Gaa-2647 | Gasterosteus aculeatus | 29.26 | 8e-46 | 174 |
| LLPS-Fud-2682 | Fukomys damarensis | 29.24 | 1e-41 | 161 |
| LLPS-Orl-0732 | Oryzias latipes | 29.12 | 8e-49 | 182 |
| LLPS-Orn-1488 | Oreochromis niloticus | 29.12 | 4e-45 | 172 |
| LLPS-Bot-3444 | Bos taurus | 29.11 | 1e-42 | 164 |
| LLPS-Vir-0644 | Vigna radiata | 29.09 | 1e-35 | 147 |
| LLPS-Sei-0800 | Setaria italica | 28.95 | 1e-38 | 154 |
| LLPS-Orgl-0380 | Oryza glumaepatula | 28.95 | 4e-38 | 150 |
| LLPS-Sob-2395 | Sorghum bicolor | 28.95 | 6e-40 | 156 |
| LLPS-Viv-2037 | Vitis vinifera | 28.94 | 9e-41 | 159 |
| LLPS-Met-0203 | Medicago truncatula | 28.85 | 1e-39 | 155 |
| LLPS-Scp-0812 | Schizosaccharomyces pombe | 28.84 | 2e-41 | 159 |
| LLPS-Mel-0771 | Melampsora laricipopulina | 28.83 | 6e-36 | 144 |
| LLPS-Pof-0429 | Poecilia formosa | 28.83 | 4e-45 | 172 |
| LLPS-Tar-3389 | Takifugu rubripes | 28.82 | 4e-45 | 172 |
| LLPS-Scm-2478 | Scophthalmus maximus | 28.7 | 1e-45 | 173 |
| LLPS-Ova-1052 | Ovis aries | 28.69 | 7e-40 | 156 |
| LLPS-Gog-1870 | Gorilla gorilla | 28.66 | 4e-41 | 160 |
| LLPS-Php-0376 | Physcomitrella patens | 28.66 | 4e-37 | 148 |
| LLPS-Leo-2009 | Lepisosteus oculatus | 28.66 | 6e-45 | 171 |
| LLPS-Glm-1448 | Glycine max | 28.66 | 2e-41 | 161 |
| LLPS-Xim-0128 | Xiphophorus maculatus | 28.6 | 9e-47 | 177 |
| LLPS-Ten-2170 | Tetraodon nigroviridis | 28.6 | 9e-45 | 171 |
| LLPS-Brn-1037 | Brassica napus | 28.57 | 2e-40 | 158 |
| LLPS-Bro-1350 | Brassica oleracea | 28.57 | 4e-40 | 157 |
| LLPS-Brr-0245 | Brassica rapa | 28.57 | 1e-40 | 158 |
| LLPS-Sot-2013 | Solanum tuberosum | 28.54 | 6e-32 | 133 |
| LLPS-Art-0536 | Arabidopsis thaliana | 28.48 | 6e-39 | 154 |
| LLPS-Dac-0021 | Daucus carota | 28.46 | 6e-32 | 133 |
| LLPS-Via-1547 | Vigna angularis | 28.45 | 8e-38 | 150 |
| LLPS-Orni-0384 | Oryza nivara | 28.45 | 1e-37 | 149 |
| LLPS-Ori-0202 | Oryza indica | 28.45 | 3e-37 | 149 |
| LLPS-Orb-0983 | Oryza barthii | 28.45 | 2e-37 | 149 |
| LLPS-Org-0742 | Oryza glaberrima | 28.45 | 2e-37 | 149 |
| LLPS-Orr-1232 | Oryza rufipogon | 28.45 | 3e-37 | 149 |
| LLPS-Ors-1703 | Oryza sativa | 28.45 | 3e-37 | 149 |
| LLPS-Drm-0499 | Drosophila melanogaster | 28.38 | 7e-40 | 155 |
| LLPS-Nia-0935 | Nicotiana attenuata | 28.33 | 2e-36 | 146 |
| LLPS-Tru-0058 | Triticum urartu | 28.32 | 3e-33 | 136 |
| LLPS-Phv-2265 | Phaseolus vulgaris | 28.25 | 2e-41 | 161 |
| LLPS-Orm-1048 | Oryza meridionalis | 28.23 | 1e-36 | 147 |
| LLPS-Zem-1214 | Zea mays | 28.2 | 3e-37 | 148 |
| LLPS-Put-0557 | Puccinia triticina | 28.11 | 4e-36 | 144 |
| LLPS-Prp-1684 | Prunus persica | 28.11 | 2e-38 | 152 |
| LLPS-Coc-1176 | Corchorus capsularis | 28.11 | 8e-37 | 147 |
| LLPS-Orbr-0396 | Oryza brachyantha | 28.07 | 3e-34 | 139 |
| LLPS-Asg-1243 | Ashbya gossypii | 27.99 | 6e-44 | 167 |
| LLPS-Miv-0966 | Microbotryum violaceum | 27.93 | 5e-30 | 126 |
| LLPS-Arl-1117 | Arabidopsis lyrata | 27.92 | 1e-37 | 149 |
| LLPS-Gor-0026 | Gossypium raimondii | 27.92 | 2e-36 | 146 |
| LLPS-Lep-0771 | Leersia perrieri | 27.85 | 2e-36 | 146 |
| LLPS-Scf-0792 | Scleropages formosus | 27.83 | 2e-44 | 169 |
| LLPS-Hea-1498 | Helianthus annuus | 27.75 | 2e-34 | 140 |
| LLPS-Dio-3263 | Dipodomys ordii | 27.72 | 1e-26 | 117 |
| LLPS-Cus-2286 | Cucumis sativus | 27.61 | 9e-36 | 144 |
| LLPS-Pot-1743 | Populus trichocarpa | 27.61 | 9e-38 | 150 |
| LLPS-Amt-0753 | Amborella trichopoda | 27.33 | 2e-35 | 143 |
| LLPS-Pug-0323 | Puccinia graminis | 26.68 | 6e-34 | 138 |
| LLPS-Chr-1448 | Chlamydomonas reinhardtii | 26.21 | 4e-30 | 127 |
| LLPS-Gas-1317 | Galdieria sulphuraria | 25.96 | 8e-25 | 112 |
| LLPS-Sac-1420 | Saccharomyces cerevisiae | 25.47 | 2e-44 | 168 |