DrLLPS - Data resource of LLPS

LLPS-Ast-1048
ATEG_06767

Integrated Annotations

▼ OVERVIEW


Status:	Unreviewed
Protein Name:	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
Gene Name:	ATEG_06767
Ensembl Gene:	ATEG_06767
Ensembl Protein:	EAU33311
Organism:	Aspergillus terreus
Taxa ID:	341663
LLPS Type:	Others

▼ PROPERTY

——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:

Condensate	Evidence	Orthologs
Stress granule, Others	Predicted from orthologs	(View)

Organism	DrLLPS ID	UniProt ID	LLPS type	Condensate	Identity	E-value	Score
Homo sapiens	LLPS-Hos-1291	P04843	Client	Stress granule, Postsynaptic density	31.25	7e-44	168

▼ FUNCTION

Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

▼ CROSS REFERENCE

Database	Nucleotide ID	Protein ID
Ensembl	EAU33311	EAU33311
UniProt		Q0CHR7, Q0CHR7_ASPTN
GeneBank	CH476602	EAU33311.1
RefSeq	XM_001215945.1	XP_001215945.1

▼ SEQUENCE

Protein Sequence (FASTA)
1 MRPFTAIAAV CGLFTSLACA AESTAADFTP PPAFKNVNLV RTTNLEKGYV RETINVVVEN 60 61 VDTEPRSSYY LAMPTEVFDK VGGLEVRDKK APEKGRFEVD SLLVDSPSDV QYFVIDFPEP 120 121 LAPKSQMTLG ISYYILNALS PRPAAIQQSD KQYLSYSFSA YTPSAYDTAT QKTMLKLPST 180 181 NVPEYTTTSG LKSGSDPERQ GTAYTYGPYD AVAARTTYPV TVRYEFTKPV ITASLLERDV 240 241 EVSHWGGNLA TEERYWLRNN GSALATQFSR VEWTVANFQQ MPSSAIRELR VPLKPGAVDP 300 301 YFTDDIGNVS TSRFRPGKPP ARDASLELKP RYPVFGGWNY SFRIGWNDDL AAYLRAVSDS 360 361 AYVLKVPFLE GPKVAEGVQY EHVVVRVILP EGARNVRYEL LDKDSSNGLP NSANIKASVT 420 421 PHKTFMDTLG RTALTLTVDN LSDEARDAQL LVTYDYSFWD GMRKPVTITA GLLTVFVAAW 480 481 AIGNIDVSIK KR 492

Protein Sequence (FASTA)

1     MRPFTAIAAV  CGLFTSLACA  AESTAADFTP  PPAFKNVNLV  RTTNLEKGYV  RETINVVVEN  60
61    VDTEPRSSYY  LAMPTEVFDK  VGGLEVRDKK  APEKGRFEVD  SLLVDSPSDV  QYFVIDFPEP  120
121   LAPKSQMTLG  ISYYILNALS  PRPAAIQQSD  KQYLSYSFSA  YTPSAYDTAT  QKTMLKLPST  180
181   NVPEYTTTSG  LKSGSDPERQ  GTAYTYGPYD  AVAARTTYPV  TVRYEFTKPV  ITASLLERDV  240
241   EVSHWGGNLA  TEERYWLRNN  GSALATQFSR  VEWTVANFQQ  MPSSAIRELR  VPLKPGAVDP  300
301   YFTDDIGNVS  TSRFRPGKPP  ARDASLELKP  RYPVFGGWNY  SFRIGWNDDL  AAYLRAVSDS  360
361   AYVLKVPFLE  GPKVAEGVQY  EHVVVRVILP  EGARNVRYEL  LDKDSSNGLP  NSANIKASVT  420
421   PHKTFMDTLG  RTALTLTVDN  LSDEARDAQL  LVTYDYSFWD  GMRKPVTITA  GLLTVFVAAW  480
481   AIGNIDVSIK  KR  492

▼ KEYWORD

ID	Family
KW-0181	Complete proteome
KW-0256	Endoplasmic reticulum
KW-0472	Membrane
KW-1185	Reference proteome
KW-0732	Signal
KW-0812	Transmembrane
KW-1133	Transmembrane helix

▼ GENE ONTOLOGY

ID	Classification	Description
GO:0005789	Cellular Component	Endoplasmic reticulum membrane
GO:0016021	Cellular Component	Integral component of membrane
GO:0004579	Molecular Function	Dolichyl-diphosphooligosaccharide-protein glycotransferase activity
GO:0006486	Biological Process	Protein glycosylation

▼ ORTHOLOGY

DrLLPS ID	Organism	Identity	E-value	Score
LLPS-Asf-1125	Aspergillus flavus	78.2	0.0	785
LLPS-Aso-1328	Aspergillus oryzae	78.2	0.0	785
LLPS-Asfu-0780	Aspergillus fumigatus	73.41	0.0	769
LLPS-Nef-1269	Neosartorya fischeri	72.96	0.0	742
LLPS-Asni-1533	Aspergillus niger	72.02	0.0	724
LLPS-Asc-0017	Aspergillus clavatus	71.23	0.0	753
LLPS-Asn-1462	Aspergillus nidulans	69.25	0.0	727
LLPS-Pytr-0743	Pyrenophora triticirepentis	55.93	0.0	543
LLPS-Pyt-1539	Pyrenophora teres	55.34	0.0	558
LLPS-Lem-1253	Leptosphaeria maculans	53.56	0.0	550
LLPS-Dos-1283	Dothistroma septosporum	52.34	5e-174	506
LLPS-Phn-1522	Phaeosphaeria nodorum	52.28	1e-180	523
LLPS-Scs-0901	Sclerotinia sclerotiorum	50.99	6e-172	501
LLPS-Zyt-1266	Zymoseptoria tritici	50.5	5e-170	496
LLPS-Nec-1253	Neurospora crassa	49.89	5e-162	476
LLPS-Cog-0742	Colletotrichum gloeosporioides	48.51	2e-154	456
LLPS-Ved-1147	Verticillium dahliae	48.49	1e-162	477
LLPS-Trr-1588	Trichoderma reesei	48.08	2e-163	479
LLPS-Map-0118	Magnaporthe poae	47.42	9e-154	454
LLPS-Trv-0707	Trichoderma virens	47.27	6e-159	468
LLPS-Fus-0581	Fusarium solani	46.98	2e-156	461
LLPS-Beb-0455	Beauveria bassiana	46.98	7e-158	465
LLPS-Cogr-1080	Colletotrichum graminicola	46.9	2e-152	451
LLPS-Blg-1557	Blumeria graminis	46.47	2e-148	443
LLPS-Gag-1506	Gaeumannomyces graminis	46.3	1e-153	454
LLPS-Coo-1405	Colletotrichum orbiculare	46.29	5e-160	471
LLPS-Mao-1562	Magnaporthe oryzae	46.2	8e-157	462
LLPS-Fuv-0686	Fusarium verticillioides	44.79	8e-150	445
LLPS-Tum-1273	Tuber melanosporum	43.56	9e-132	398
LLPS-Fuo-1261	Fusarium oxysporum	40.67	3e-122	373
LLPS-Abg-1264	Absidia glauca	38.89	5e-49	175
LLPS-Miv-0966	Microbotryum violaceum	33.45	1e-28	122
LLPS-Yal-0849	Yarrowia lipolytica	33.12	2e-63	219
LLPS-Spr-0368	Sporisorium reilianum	32.39	1e-44	169
LLPS-Fia-0374	Ficedula albicollis	31.87	8e-47	176
LLPS-Anp-1575	Anas platyrhynchos	31.87	1e-46	176
LLPS-Ora-0057	Ornithorhynchus anatinus	31.6	1e-18	90.9
LLPS-Sol-0263	Solanum lycopersicum	31.55	5e-32	134
LLPS-Pes-0990	Pelodiscus sinensis	31.53	7e-48	178
LLPS-Meg-1815	Meleagris gallopavo	31.51	3e-47	177
LLPS-Tag-0725	Taeniopygia guttata	31.51	4e-47	176
LLPS-Usm-0219	Ustilago maydis	31.51	6e-42	161
LLPS-Mal-3537	Mandrillus leucophaeus	31.5	3e-29	122
LLPS-Man-0989	Macaca nemestrina	31.25	2e-44	169
LLPS-Poa-1009	Pongo abelii	31.25	4e-44	167
LLPS-Pap-1556	Pan paniscus	31.16	2e-44	169
LLPS-Cas-3098	Carlito syrichta	31.14	2e-29	123
LLPS-Crn-0929	Cryptococcus neoformans	31.02	7e-51	186
LLPS-Mod-1022	Monodelphis domestica	31.02	4e-48	181
LLPS-Urm-0141	Ursus maritimus	30.92	3e-44	168
LLPS-Cae-1532	Caenorhabditis elegans	30.8	3e-47	177
LLPS-Cii-1298	Ciona intestinalis	30.55	2e-44	167
LLPS-Otg-1428	Otolemur garnettii	30.47	6e-49	182
LLPS-Lac-1608	Latimeria chalumnae	30.47	3e-46	175
LLPS-Gaga-2017	Gallus gallus	30.36	9e-47	177
LLPS-Nia-0935	Nicotiana attenuata	30.22	4e-44	169
LLPS-Mea-4314	Mesocricetus auratus	30.19	1e-48	181
LLPS-Mum-4056	Mus musculus	30.19	5e-48	180
LLPS-Sem-0306	Selaginella moellendorffii	30.15	2e-51	190
LLPS-Rhb-1358	Rhinopithecus bieti	30.13	2e-48	181
LLPS-Cea-0408	Cercocebus atys	29.98	9e-48	179
LLPS-Maf-1094	Macaca fascicularis	29.98	9e-48	179
LLPS-Paa-0624	Papio anubis	29.98	9e-48	179
LLPS-Loa-3398	Loxodonta africana	29.98	2e-47	179
LLPS-Pat-1433	Pan troglodytes	29.98	1e-47	179
LLPS-Hos-1291	Homo sapiens	29.98	1e-47	179
LLPS-Nol-1156	Nomascus leucogenys	29.98	2e-47	179
LLPS-Mam-3995	Macaca mulatta	29.98	9e-48	179
LLPS-Eqc-2088	Equus caballus	29.98	5e-47	177
LLPS-Aon-4087	Aotus nancymaae	29.95	7e-45	171
LLPS-Chs-0180	Chlorocebus sabaeus	29.92	7e-48	179
LLPS-Scj-0533	Schizosaccharomyces japonicus	29.85	1e-56	201
LLPS-Myl-4035	Myotis lucifugus	29.82	1e-46	176
LLPS-Vir-0090	Vigna radiata	29.82	2e-49	182
LLPS-Mel-0771	Melampsora laricipopulina	29.8	5e-41	159
LLPS-Cis-1651	Ciona savignyi	29.78	5e-49	182
LLPS-Caj-1780	Callithrix jacchus	29.76	1e-47	179
LLPS-Mup-3450	Mustela putorius furo	29.76	1e-46	176
LLPS-Ran-1204	Rattus norvegicus	29.76	6e-47	177
LLPS-Caf-0051	Canis familiaris	29.76	5e-47	177
LLPS-Kop-0887	Komagataella pastoris	29.74	3e-49	181
LLPS-Scc-1262	Schizosaccharomyces cryophilus	29.71	8e-48	177
LLPS-Icp-0139	Ictalurus punctatus	29.58	1e-41	161
LLPS-Xet-0497	Xenopus tropicalis	29.57	6e-50	185
LLPS-Aim-2958	Ailuropoda melanoleuca	29.55	1e-46	176
LLPS-Fec-3269	Felis catus	29.55	2e-46	175
LLPS-Bot-3444	Bos taurus	29.51	1e-45	173
LLPS-Anc-3055	Anolis carolinensis	29.42	4e-47	177
LLPS-Sus-1378	Sus scrofa	29.37	2e-44	170
LLPS-Sot-2013	Solanum tuberosum	29.35	8e-38	150
LLPS-Amt-0753	Amborella trichopoda	29.35	2e-45	172
LLPS-Fud-2682	Fukomys damarensis	29.34	1e-44	170
LLPS-Orc-4031	Oryctolagus cuniculus	29.33	8e-49	182
LLPS-Thc-1903	Theobroma cacao	29.28	3e-42	163
LLPS-Cap-3127	Cavia porcellus	29.18	4e-45	172
LLPS-Scp-0812	Schizosaccharomyces pombe	29.14	1e-46	174
LLPS-Sah-3080	Sarcophilus harrisii	29.07	1e-41	161
LLPS-Mua-0181	Musa acuminata	28.97	2e-41	160
LLPS-Coc-1176	Corchorus capsularis	28.96	3e-42	163
LLPS-Dac-0021	Daucus carota	28.95	8e-38	150
LLPS-Viv-2037	Vitis vinifera	28.88	2e-45	172
LLPS-Met-0203	Medicago truncatula	28.76	8e-44	168
LLPS-Asg-1243	Ashbya gossypii	28.72	8e-50	182
LLPS-Orn-1488	Oreochromis niloticus	28.7	5e-45	171
LLPS-Asm-2653	Astyanax mexicanus	28.69	5e-45	171
LLPS-Cus-2286	Cucumis sativus	28.67	8e-41	159
LLPS-Mae-0897	Manihot esculenta	28.67	2e-43	166
LLPS-Ova-1052	Ovis aries	28.63	8e-44	168
LLPS-Glm-1448	Glycine max	28.6	3e-46	175
LLPS-Gog-1870	Gorilla gorilla	28.57	5e-44	169
LLPS-Hov-0598	Hordeum vulgare	28.57	2e-41	160
LLPS-Arl-1117	Arabidopsis lyrata	28.54	1e-42	164
LLPS-Tar-3389	Takifugu rubripes	28.51	5e-45	171
LLPS-Gor-0026	Gossypium raimondii	28.51	9e-45	171
LLPS-Gaa-2647	Gasterosteus aculeatus	28.48	5e-44	168
LLPS-Brd-0070	Brachypodium distachyon	28.45	2e-41	160
LLPS-Leo-2009	Lepisosteus oculatus	28.4	4e-47	177
LLPS-Scf-0792	Scleropages formosus	28.4	1e-45	173
LLPS-Hea-1498	Helianthus annuus	28.29	2e-43	166
LLPS-Orl-0732	Oryzias latipes	28.29	9e-45	171
LLPS-Ten-2170	Tetraodon nigroviridis	28.29	5e-45	171
LLPS-Brn-1037	Brassica napus	28.12	1e-44	170
LLPS-Brr-0245	Brassica rapa	28.12	1e-44	171
LLPS-Sac-1420	Saccharomyces cerevisiae	28.11	9e-58	204
LLPS-Art-0536	Arabidopsis thaliana	28.09	2e-43	167
LLPS-Bro-1350	Brassica oleracea	28.07	3e-45	172
LLPS-Via-1547	Vigna angularis	28.04	9e-41	159
LLPS-Pot-1743	Populus trichocarpa	27.98	9e-42	162
LLPS-Prp-1684	Prunus persica	27.98	1e-41	161
LLPS-Sob-2395	Sorghum bicolor	27.95	9e-41	159
LLPS-Pug-0323	Puccinia graminis	27.94	2e-41	160
LLPS-Php-0376	Physcomitrella patens	27.82	4e-44	169
LLPS-Tra-0918	Triticum aestivum	27.79	1e-40	158
LLPS-Scm-2478	Scophthalmus maximus	27.74	3e-43	166
LLPS-Put-0557	Puccinia triticina	27.67	1e-40	157
LLPS-Phv-2265	Phaseolus vulgaris	27.65	5e-44	168
LLPS-Pof-0429	Poecilia formosa	27.57	2e-43	167
LLPS-Orgl-0380	Oryza glumaepatula	27.47	3e-40	156
LLPS-Orp-0712	Oryza punctata	27.47	7e-40	156
LLPS-Orm-1048	Oryza meridionalis	27.47	6e-40	156
LLPS-Drm-0499	Drosophila melanogaster	27.45	9e-43	163
LLPS-Chr-1448	Chlamydomonas reinhardtii	27.37	2e-37	149
LLPS-Orni-0384	Oryza nivara	27.25	2e-39	155
LLPS-Ori-0202	Oryza indica	27.25	2e-39	154
LLPS-Orb-0983	Oryza barthii	27.25	3e-39	154
LLPS-Ors-1703	Oryza sativa	27.25	2e-39	154
LLPS-Org-0742	Oryza glaberrima	27.25	3e-39	154
LLPS-Orr-1232	Oryza rufipogon	27.25	2e-39	154
LLPS-Xim-0128	Xiphophorus maculatus	27.16	1e-43	167
LLPS-Lep-0771	Leersia perrieri	27.03	2e-39	155
LLPS-Dio-3263	Dipodomys ordii	27.01	1e-27	120
LLPS-Sei-0800	Setaria italica	26.91	4e-39	155
LLPS-Zem-1214	Zea mays	26.62	5e-38	150
LLPS-Orbr-0396	Oryza brachyantha	26.37	7e-36	144
LLPS-Dar-0592	Danio rerio	26.23	2e-41	161
LLPS-Tru-0058	Triticum urartu	26.15	3e-34	139
LLPS-Gas-1317	Galdieria sulphuraria	24.94	6e-28	120

LLPS-Ast-1048ATEG_06767

Protein Sequence

Nucleotide Sequence

LLPS-Ast-1048
ATEG_06767