• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Coc-1094
CCACVL1_15684

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Eukaryotic translation initiation factor 3 subunit D
Gene Name: CCACVL1_15684
Ensembl Gene: CCACVL1_15684
Ensembl Protein: OMO76442
Organism: Corchorus capsularis
Taxa ID: 210143
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granulePredicted from orthologs(View)

▼ FUNCTION

mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblOMO76442OMO76442
UniProtA0A1R3I1I2, A0A1R3I1I2_COCAP
GeneBankAWWV01010883OMO76442.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MVGVFEVGAV  PFNSDGWGPP  ESIAATPATT  TIPLHVPFAP  FSRSDKLGRI  ADFTRNFSSS  60
61    TANPSNRPSS  GKPGAANASD  APFDFSLDVD  AFALGNDDDS  SFRLVDAKPP  PRPKFGPKWR  120
121   FNQHRPQLPQ  RRDEEVEAKK  REAEKERARR  DRLYNLNRSN  QNQQRREAAI  FKSSVDIQPE  180
181   WNMLEQIPFS  TFSKVSFTVP  EPEDLLLCGA  LEYYDRSFDR  ITPKNERRLE  RFKNRNFFKV  240
241   TTTDDPVIRR  LANEDKATVF  ATDTILATLM  CATRSVYSWD  IVVQRVGNKL  FFDKRDGSQL  300
301   DLLSVHETSQ  EPLPEAKDDI  NSAYSLSVEA  AYINQNFSQQ  VLVRDGNKVT  FDEPNPFANE  360
361   GDEVASVAYR  YRRWKLDDNM  HLVARCEVQS  VVEVNKQKSF  VTLNALNEFD  PKYSGVDWRQ  420
421   KLETQRGAVL  ATELKNNANK  LAKWTAQALL  ASADLMKLGY  VSRVHPRDHF  NHVILAVVGY  480
481   KPRDFAAQIN  LNTSNMWGIV  KSIVDLCMKL  NEGKYVLVKD  PSKPQVRIYE  VPADAFENDY  540
541   VEEPLPEEEQ  VQPPTEDAET  GEANGATNDV  EDKEIEAQT  579
Nucleotide CDS Sequence (FASTA)
1     ATGGTAGGAG  TTTTTGAAGT  AGGCGCAGTC  CCCTTTAATT  CCGACGGCTG  GGGTCCGCCG  60
61    GAATCCATCG  CCGCCACACC  AGCCACCACT  ACCATCCCTC  TCCACGTCCC  CTTCGCTCCC  120
121   TTCTCGCGCT  CCGATAAACT  CGGTCGGATC  GCCGACTTTA  CCCGTAATTT  TTCTTCCTCC  180
181   ACTGCCAACC  CATCCAACCG  CCCTTCTTCT  GGTAAACCCG  GCGCAGCCAA  TGCCTCCGAT  240
241   GCTCCCTTTG  ATTTCTCTCT  GGATGTCGAC  GCCTTCGCTC  TCGGCAACGA  CGACGATTCC  300
301   TCTTTCCGTT  TAGTCGACGC  GAAGCCTCCT  CCTAGGCCTA  AATTCGGCCC  TAAGTGGCGT  360
361   TTCAACCAGC  ACCGACCTCA  GCTCCCTCAA  CGACGGGACG  AAGAGGTTGA  GGCCAAGAAA  420
421   AGGGAGGCCG  AGAAAGAACG  GGCACGCCGT  GACCGTCTTT  ACAATCTCAA  CCGGTCCAAT  480
481   CAGAATCAGC  AACGTCGGGA  AGCCGCAATT  TTCAAGTCCT  CCGTCGATAT  CCAACCCGAA  540
541   TGGAACATGC  TGGAGCAAAT  CCCCTTCTCA  ACATTCTCAA  AGGTATCATT  TACCGTTCCT  600
601   GAACCTGAAG  ATTTACTCCT  ATGTGGTGCT  TTGGAGTATT  ACGATAGGTC  TTTTGATCGA  660
661   ATCACCCCGA  AGAACGAAAG  GAGACTAGAA  AGGTTCAAGA  ACAGGAACTT  CTTTAAAGTC  720
721   ACCACGACTG  ACGATCCAGT  GATCCGAAGA  TTGGCCAATG  AAGATAAAGC  TACTGTCTTT  780
781   GCAACTGATA  CTATTCTGGC  AACCTTAATG  TGTGCTACCA  GGTCAGTTTA  TTCATGGGAT  840
841   ATTGTTGTTC  AACGTGTTGG  GAATAAGCTA  TTTTTTGATA  AGAGAGATGG  GTCGCAATTA  900
901   GATTTGTTGT  CTGTCCATGA  GACTTCTCAG  GAGCCATTGC  CTGAAGCTAA  AGATGATATT  960
961   AACTCTGCAT  ACTCATTGAG  TGTTGAGGCT  GCTTATATAA  ATCAGAATTT  TTCACAGCAG  1020
1021  GTTCTGGTTA  GGGATGGGAA  TAAGGTTACT  TTCGATGAGC  CAAACCCATT  TGCCAATGAA  1080
1081  GGTGATGAGG  TGGCTTCTGT  GGCATATAGA  TATAGGAGGT  GGAAGCTTGA  TGATAATATG  1140
1141  CATTTGGTTG  CACGGTGTGA  GGTTCAGAGT  GTTGTTGAGG  TTAATAAGCA  GAAGTCTTTC  1200
1201  GTTACTTTGA  ATGCACTTAA  CGAGTTTGAT  CCTAAGTATT  CTGGTGTTGA  TTGGAGGCAG  1260
1261  AAGTTGGAGA  CACAAAGGGG  TGCTGTCTTA  GCTACTGAGT  TGAAGAACAA  TGCAAATAAA  1320
1321  TTGGCTAAAT  GGACTGCTCA  AGCTCTCTTA  GCCAGTGCTG  ATTTGATGAA  ATTGGGTTAT  1380
1381  GTTTCTAGGG  TGCATCCTAG  GGATCATTTT  AACCATGTTA  TATTGGCTGT  TGTTGGGTAT  1440
1441  AAGCCAAGGG  ATTTTGCTGC  ACAAATTAAT  CTGAATACTT  CAAATATGTG  GGGGATTGTG  1500
1501  AAGTCTATCG  TGGACTTGTG  TATGAAGTTG  AATGAGGGGA  AATATGTGCT  TGTGAAGGAT  1560
1561  CCATCTAAGC  CTCAAGTCAG  GATTTATGAG  GTTCCAGCTG  ATGCTTTTGA  GAATGACTAT  1620
1621  GTGGAAGAAC  CATTGCCAGA  AGAGGAACAG  GTTCAGCCAC  CTACTGAGGA  TGCTGAAACT  1680
1681  GGGGAAGCAA  ATGGCGCAAC  AAATGATGTT  GAGGATAAGG  AGATTGAGGC  ACAAACTTAA  1740

▼ KEYWORD

ID
Family
Coiled coil
Complete proteome
Cytoplasm
Initiation factor
Protein biosynthesis
Reference proteome
RNA-binding

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Eukaryotic 43S preinitiation complex
Cellular Component
Eukaryotic 48S preinitiation complex
Cellular Component
Eukaryotic translation initiation factor 3 complex
Molecular Function
MRNA cap binding
Molecular Function
Translation initiation factor activity
Biological Process
Cap-dependent translational initiation
Biological Process
Formation of cytoplasmic translation initiation complex

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Thc-2431Theobroma cacao93.440.0 993
LLPS-Gor-2060Gossypium raimondii92.40.0 979
LLPS-Via-2135Vigna angularis91.670.0 723
LLPS-Mae-0920Manihot esculenta86.90.0 903
LLPS-Pot-2623Populus trichocarpa86.40.0 897
LLPS-Cus-0362Cucumis sativus84.990.0 890
LLPS-Prp-2201Prunus persica84.060.0 882
LLPS-Phv-0543Phaseolus vulgaris83.910.0 861
LLPS-Viv-1605Vitis vinifera83.820.0 875
LLPS-Vir-0815Vigna radiata83.740.0 863
LLPS-Glm-1550Glycine max82.870.0 856
LLPS-Sol-0114Solanum lycopersicum81.090.0 828
LLPS-Nia-2380Nicotiana attenuata80.950.0 850
LLPS-Orbr-1877Oryza brachyantha80.560.0 614
LLPS-Sot-1983Solanum tuberosum80.10.0 831
LLPS-Dac-2313Daucus carota79.620.0 815
LLPS-Hea-2399Helianthus annuus79.10.0 826
LLPS-Amt-2061Amborella trichopoda78.480.0 791
LLPS-Met-1922Medicago truncatula78.420.0 816
LLPS-Arl-1845Arabidopsis lyrata78.090.0 827
LLPS-Art-2168Arabidopsis thaliana78.040.0 825
LLPS-Tru-0395Triticum urartu76.820.0 610
LLPS-Brn-0441Brassica napus76.410.0 788
LLPS-Brr-1662Brassica rapa76.240.0 789
LLPS-Sem-1792Selaginella moellendorffii75.380.0 662
LLPS-Bro-1749Brassica oleracea73.230.0 784
LLPS-Sob-2536Sorghum bicolor73.060.0 733
LLPS-Zem-0300Zea mays72.930.0 736
LLPS-Sei-2512Setaria italica72.880.0 737
LLPS-Lep-1032Leersia perrieri72.560.0 733
LLPS-Orni-1287Oryza nivara72.010.0 729
LLPS-Ori-1561Oryza indica72.010.0 729
LLPS-Orb-1996Oryza barthii72.010.0 729
LLPS-Orgl-1154Oryza glumaepatula72.010.0 729
LLPS-Orp-1597Oryza punctata72.010.0 729
LLPS-Ors-2150Oryza sativa72.010.0 729
LLPS-Org-2176Oryza glaberrima72.010.0 729
LLPS-Orr-1504Oryza rufipogon72.010.0 729
LLPS-Orm-0984Oryza meridionalis72.010.0 729
LLPS-Brd-1599Brachypodium distachyon70.460.0 712
LLPS-Tra-2851Triticum aestivum69.430.0 694
LLPS-Hov-1957Hordeum vulgare69.060.0 695
LLPS-Php-2446Physcomitrella patens68.90.0 558
LLPS-Mua-0097Musa acuminata62.870.0 635
LLPS-Tum-0865Tuber melanosporum56.541e-101 317
LLPS-Leo-3409Lepisosteus oculatus56.416e-34 130
LLPS-Cii-1655Ciona intestinalis51.351e-121 377
LLPS-Cis-0512Ciona savignyi50.663e-122 379
LLPS-Mup-2657Mustela putorius furo49.521e-54 197
LLPS-Asni-0601Aspergillus niger49.491e-115 363
LLPS-Asn-1583Aspergillus nidulans49.232e-115 362
LLPS-Pyt-0693Pyrenophora teres49.231e-113 357
LLPS-Phn-1564Phaeosphaeria nodorum49.235e-116 363
LLPS-Pytr-1636Pyrenophora triticirepentis49.231e-113 357
LLPS-Blg-0787Blumeria graminis49.213e-118 369
LLPS-Fus-0084Fusarium solani48.962e-111 352
LLPS-Zyt-1203Zymoseptoria tritici48.846e-112 353
LLPS-Gag-1219Gaeumannomyces graminis48.76e-116 363
LLPS-Ved-1368Verticillium dahliae48.72e-106 338
LLPS-Dos-1516Dothistroma septosporum48.592e-107 341
LLPS-Osl-0456Ostreococcus lucimarinus48.525e-115 355
LLPS-Map-0162Magnaporthe poae48.453e-116 364
LLPS-Scj-0627Schizosaccharomyces japonicus48.431e-110 349
LLPS-Lem-1095Leptosphaeria maculans48.287e-110 341
LLPS-Asf-0225Aspergillus flavus48.211e-109 347
LLPS-Aso-1184Aspergillus oryzae48.211e-109 347
LLPS-Asfu-0693Aspergillus fumigatus48.211e-113 357
LLPS-Nec-0345Neurospora crassa48.28e-109 345
LLPS-Asc-1486Aspergillus clavatus48.12e-114 359
LLPS-Nef-1024Neosartorya fischeri47.965e-113 356
LLPS-Coo-1607Colletotrichum orbiculare47.946e-110 348
LLPS-Trr-1436Trichoderma reesei47.856e-113 356
LLPS-Chc-0718Chondrus crispus47.735e-102 326
LLPS-Fuv-1542Fusarium verticillioides47.551e-112 354
LLPS-Fuo-0517Fusarium oxysporum47.551e-112 355
LLPS-Mao-1568Magnaporthe oryzae47.534e-113 356
LLPS-Trv-0019Trichoderma virens47.386e-110 348
LLPS-Cog-0457Colletotrichum gloeosporioides47.161e-109 344
LLPS-Cogr-1431Colletotrichum graminicola46.911e-108 345
LLPS-Cae-1655Caenorhabditis elegans46.838e-102 326
LLPS-Pug-0543Puccinia graminis46.561e-105 337
LLPS-Put-1256Puccinia triticina46.157e-93 299
LLPS-Scc-0597Schizosaccharomyces cryophilus46.091e-105 336
LLPS-Crn-1580Cryptococcus neoformans45.774e-108 342
LLPS-Scp-0485Schizosaccharomyces pombe45.671e-101 326
LLPS-Beb-0326Beauveria bassiana45.577e-107 340
LLPS-Spr-1159Sporisorium reilianum45.045e-104 332
LLPS-Usm-0200Ustilago maydis44.928e-103 329
LLPS-Fia-2479Ficedula albicollis44.575e-139 422
LLPS-Gaga-1637Gallus gallus44.575e-139 422
LLPS-Miv-0073Microbotryum violaceum44.536e-97 313
LLPS-Lac-3153Latimeria chalumnae44.472e-143 433
LLPS-Tag-3257Taeniopygia guttata44.387e-138 419
LLPS-Icp-1986Ictalurus punctatus44.23e-137 418
LLPS-Sah-2261Sarcophilus harrisii43.731e-136 416
LLPS-Orc-1553Oryctolagus cuniculus43.737e-136 414
LLPS-Mod-3739Monodelphis domestica43.542e-136 415
LLPS-Asm-0924Astyanax mexicanus43.493e-137 417
LLPS-Caj-4346Callithrix jacchus43.455e-136 414
LLPS-Gog-4141Gorilla gorilla43.453e-136 415
LLPS-Cea-4551Cercocebus atys43.453e-136 415
LLPS-Aon-0903Aotus nancymaae43.453e-136 415
LLPS-Chs-1975Chlorocebus sabaeus43.453e-136 415
LLPS-Maf-3286Macaca fascicularis43.453e-136 415
LLPS-Aim-2630Ailuropoda melanoleuca43.453e-136 415
LLPS-Paa-1460Papio anubis43.453e-136 415
LLPS-Mal-4410Mandrillus leucophaeus43.453e-136 415
LLPS-Rhb-4374Rhinopithecus bieti43.453e-136 415
LLPS-Loa-4471Loxodonta africana43.453e-136 415
LLPS-Man-1486Macaca nemestrina43.453e-136 415
LLPS-Fec-1161Felis catus43.455e-136 414
LLPS-Pat-4780Pan troglodytes43.453e-136 415
LLPS-Urm-3810Ursus maritimus43.453e-136 415
LLPS-Pap-3608Pan paniscus43.453e-136 415
LLPS-Hos-1129Homo sapiens43.453e-136 415
LLPS-Nol-2364Nomascus leucogenys43.453e-136 415
LLPS-Xet-0896Xenopus tropicalis43.452e-136 416
LLPS-Cas-3181Carlito syrichta43.453e-136 415
LLPS-Mam-3381Macaca mulatta43.453e-136 415
LLPS-Caf-2014Canis familiaris43.453e-136 415
LLPS-Sus-1625Sus scrofa43.274e-136 414
LLPS-Mea-3783Mesocricetus auratus43.276e-136 414
LLPS-Mum-3657Mus musculus43.276e-136 414
LLPS-Ova-0807Ovis aries43.273e-136 415
LLPS-Ran-1225Rattus norvegicus43.276e-136 414
LLPS-Bot-3680Bos taurus43.273e-136 415
LLPS-Otg-1742Otolemur garnettii43.274e-136 414
LLPS-Ict-3086Ictidomys tridecemlineatus43.274e-136 414
LLPS-Anc-1118Anolis carolinensis43.274e-138 419
LLPS-Cap-0095Cavia porcellus43.273e-135 414
LLPS-Mel-1160Melampsora laricipopulina43.21e-99 322
LLPS-Fud-2154Fukomys damarensis43.097e-136 414
LLPS-Myl-2186Myotis lucifugus43.091e-135 413
LLPS-Dio-2482Dipodomys ordii43.091e-135 413
LLPS-Pes-2903Pelodiscus sinensis43.091e-135 413
LLPS-Orn-0224Oreochromis niloticus43.011e-137 419
LLPS-Drm-0623Drosophila melanogaster42.945e-133 407
LLPS-Eqc-1780Equus caballus42.915e-135 412
LLPS-Pof-0288Poecilia formosa42.864e-138 420
LLPS-Ten-0898Tetraodon nigroviridis42.781e-134 411
LLPS-Orl-1024Oryzias latipes42.738e-138 419
LLPS-Tut-2382Tursiops truncatus42.731e-130 400
LLPS-Scf-2046Scleropages formosus42.683e-137 417
LLPS-Tar-2499Takifugu rubripes42.682e-135 413
LLPS-Dar-3011Danio rerio42.685e-137 417
LLPS-Scm-0385Scophthalmus maximus42.657e-137 416
LLPS-Xim-2863Xiphophorus maculatus42.52e-135 414
LLPS-Gaa-2485Gasterosteus aculeatus42.161e-136 416
LLPS-Gas-0815Galdieria sulphuraria41.562e-128 395
LLPS-Chr-0650Chlamydomonas reinhardtii41.252e-123 382
LLPS-Ast-0607Aspergillus terreus40.575e-35 140
LLPS-Yal-0966Yarrowia lipolytica40.531e-87 288
LLPS-Anp-2996Anas platyrhynchos39.632e-110 347
LLPS-Meg-1230Meleagris gallopavo38.062e-46 171
LLPS-Abg-0977Absidia glauca37.971e-121 379
LLPS-Poa-1913Pongo abelii37.75e-99 318
LLPS-Cym-1142Cyanidioschyzon merolae37.57e-78 266
LLPS-Ora-0494Ornithorhynchus anatinus36.629e-94 304
LLPS-Kop-1473Komagataella pastoris36.566e-74 252