• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Blg-0787
BGHDH14_bgh02450

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Eukaryotic translation initiation factor 3 subunit D
Gene Name: BGHDH14_bgh02450
Ensembl Gene: BLGH_00603
Ensembl Protein: BLGH_00603-mRNA-1
Organism: Blumeria graminis
Taxa ID: 546991
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granulePredicted from orthologs(View)

▼ FUNCTION

mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblBLGH_00603-mRNA-1BLGH_00603-mRNA-1
UniProtN1JKZ5, N1JKZ5_BLUG1
GeneBankCAUH01004870CCU81187.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MTPTALAEII  SALPCEDTWG  PPIPQDTTLN  GAPYAPYSKG  DKLGRMADWT  SEGKDGRDGR  60
61    GARQQYNRNY  RDQQVYGAGT  SSLFAAQVAE  DEFSFSVVSN  TRDSAKTRFG  RGGPFARGRG  120
121   QRGGRADTRG  GRGQFQRVGG  RGGQQGYNNY  NDRGGRGGGS  RGGRRFGWKD  YDKPQRNRDA  180
181   SVNIKPEWKM  LEEIDFNRLA  KLNLDTDEGE  DIESYGFLYY  YDRSYDKQPV  KVGERKLSVV  240
241   DRAAYNVTTS  SDPVIQELAE  KDEATIFATD  SILSMLMCSP  RSVYPWDIII  IRQGNKVFLD  300
301   KRDNATLDMV  TVNENAADAP  MDASEGSKDA  INQPGALAEE  ATYINHNFAN  QVMIENESKK  360
361   VDMPNENPFY  NPAEENEPAA  SKAYKYRRFD  LSLNDEDPVH  LIVRTELDAV  QKNAISGEDQ  420
421   FLTVKALNEF  DHKAQGSGGA  LEWRTKLVSQ  RGAVVATEMK  NNSCKLARWT  TQSIMARADI  480
481   MKLGFVSRAN  PKTNDRHVIL  GVVGWKPRDF  AQQMNLSLSN  GWGIVRTIAD  MCLKREEGKY  540
541   VLLKDPNKPM  LRLYEVPVGS  FEEEEPETID  EVEEPEN  577
Nucleotide CDS Sequence (FASTA)
1     ATGACGCCCA  CTGCGTTGGC  CGAAATCATT  TCTGCACTGC  CGTGCGAAGA  TACATGGGGT  60
61    CCGCCAATTC  CGCAGGACAC  TACGCTCAAT  GGCGCTCCTT  ATGCCCCCTA  CTCCAAGGGC  120
121   GATAAACTTG  GTCGAATGGC  AGACTGGACT  AGCGAAGGCA  AAGATGGCCG  TGACGGCCGT  180
181   GGCGCCCGCC  AGCAGTACAA  TCGGAACTAT  AGAGATCAAC  AGGTTTACGG  CGCCGGTACC  240
241   TCTTCCTTAT  TTGCTGCCCA  GGTAGCCGAA  GATGAATTCT  CTTTCTCCGT  CGTCAGCAAT  300
301   ACACGCGACT  CGGCCAAAAC  GCGATTCGGC  CGCGGCGGTC  CGTTTGCTCG  CGGCCGTGGC  360
361   CAACGAGGTG  GAAGGGCTGA  TACGAGAGGC  GGACGCGGTC  AGTTTCAGAG  AGTTGGTGGT  420
421   CGAGGAGGTC  AACAAGGATA  TAACAATTAT  AACGATCGTG  GAGGCCGTGG  TGGCGGCTCT  480
481   CGTGGCGGCC  GAAGATTTGG  ATGGAAAGAC  TACGACAAAC  CCCAGCGTAA  TCGTGACGCA  540
541   TCTGTTAATA  TCAAGCCTGA  ATGGAAAATG  CTCGAAGAGA  TAGACTTTAA  TCGGCTCGCA  600
601   AAACTCAATT  TAGATACAGA  CGAAGGCGAA  GACATCGAAA  GTTACGGATT  CCTCTATTAC  660
661   TACGACAGAT  CCTACGACAA  GCAGCCAGTC  AAAGTAGGTG  AGCGAAAATT  GAGCGTTGTT  720
721   GACCGCGCGG  CCTACAATGT  CACAACTTCA  TCAGACCCAG  TCATTCAAGA  GCTTGCAGAA  780
781   AAAGATGAGG  CAACTATCTT  TGCAACTGAT  AGCATCCTTT  CCATGCTCAT  GTGCTCTCCA  840
841   CGTTCTGTAT  ACCCTTGGGA  TATCATCATC  ATTAGGCAGG  GTAACAAGGT  CTTCCTTGAT  900
901   AAGAGAGACA  ACGCTACGCT  TGATATGGTC  ACGGTTAATG  AAAATGCGGC  TGATGCTCCG  960
961   ATGGATGCTT  CTGAGGGAAG  CAAAGACGCT  ATTAATCAGC  CAGGTGCTCT  TGCCGAGGAG  1020
1021  GCTACCTATA  TTAACCACAA  TTTTGCAAAT  CAAGTCATGA  TTGAGAATGA  GAGTAAAAAA  1080
1081  GTCGACATGC  CTAATGAGAA  TCCGTTCTAC  AATCCAGCTG  AGGAAAATGA  ACCTGCCGCA  1140
1141  AGCAAGGCAT  ATAAATATAG  GAGGTTTGAC  CTTTCTCTCA  ACGATGAAGA  CCCAGTACAC  1200
1201  CTTATAGTTC  GAACTGAGCT  AGATGCCGTT  CAGAAGAATG  CAATTAGCGG  CGAAGATCAA  1260
1261  TTTTTAACTG  TCAAAGCTCT  AAATGAGTTT  GACCACAAAG  CGCAGGGTAG  CGGTGGTGCT  1320
1321  CTCGAGTGGC  GGACAAAGCT  TGTTAGCCAG  CGCGGTGCTG  TCGTAGCTAC  CGAAATGAAA  1380
1381  AATAACAGCT  GCAAGCTAGC  AAGATGGACA  ACTCAAAGTA  TAATGGCTCG  TGCAGATATC  1440
1441  ATGAAGCTAG  GATTTGTTTC  TCGAGCTAAC  CCTAAAACTA  ATGATCGTCA  CGTCATACTT  1500
1501  GGCGTTGTTG  GGTGGAAGCC  GCGTGATTTT  GCCCAGCAGA  TGAATCTCAG  CCTTTCAAAT  1560
1561  GGATGGGGTA  TCGTGCGCAC  CATTGCTGAC  ATGTGCTTGA  AGCGTGAGGA  AGGTAAGTAT  1620
1621  GTGCTTCTAA  AAGACCCGAA  CAAGCCCATG  CTCCGCCTTT  ACGAAGTACC  AGTCGGGAGC  1680
1681  TTCGAAGAAG  AAGAGCCGGA  GACAATTGAT  GAGGTTGAAG  AGCCGGAAAA  TTGA  1734

▼ KEYWORD

ID
Family
Complete proteome
Cytoplasm
Initiation factor
Protein biosynthesis
Reference proteome
RNA-binding

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Eukaryotic 43S preinitiation complex
Cellular Component
Eukaryotic 48S preinitiation complex
Cellular Component
Eukaryotic translation initiation factor 3 complex
Molecular Function
MRNA cap binding
Molecular Function
Translation initiation factor activity
Biological Process
Cap-dependent translational initiation
Biological Process
Formation of cytoplasmic translation initiation complex

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Cog-0457Colletotrichum gloeosporioides82.094e-1479.0
LLPS-Map-0162Magnaporthe poae81.730.0 692
LLPS-Fuv-1542Fusarium verticillioides81.310.0 673
LLPS-Fuo-0517Fusarium oxysporum81.310.0 673
LLPS-Trv-0019Trichoderma virens81.220.0 680
LLPS-Gag-1219Gaeumannomyces graminis80.960.0 691
LLPS-Mao-1568Magnaporthe oryzae80.960.0 690
LLPS-Coo-1607Colletotrichum orbiculare80.810.0 658
LLPS-Cogr-1431Colletotrichum graminicola80.050.0 669
LLPS-Fus-0084Fusarium solani80.050.0 657
LLPS-Nec-0345Neurospora crassa78.540.0 663
LLPS-Trr-1436Trichoderma reesei77.670.0 656
LLPS-Beb-0326Beauveria bassiana77.660.0 661
LLPS-Ved-1368Verticillium dahliae75.380.0 617
LLPS-Zyt-1203Zymoseptoria tritici75.060.0 623
LLPS-Pyt-0693Pyrenophora teres73.470.0 607
LLPS-Tum-0865Tuber melanosporum72.981e-147 435
LLPS-Pytr-1636Pyrenophora triticirepentis72.960.0 604
LLPS-Lem-1095Leptosphaeria maculans72.650.0 572
LLPS-Nef-1024Neosartorya fischeri72.642e-31 132
LLPS-Asn-1583Aspergillus nidulans71.72e-30 129
LLPS-Phn-1564Phaeosphaeria nodorum71.430.0 598
LLPS-Asni-0601Aspergillus niger71.031e-30 130
LLPS-Dos-1516Dothistroma septosporum71.030.0 600
LLPS-Asfu-0693Aspergillus fumigatus70.092e-30 129
LLPS-Asc-1486Aspergillus clavatus69.812e-29 127
LLPS-Ast-0607Aspergillus terreus69.813e-29 124
LLPS-Aso-1184Aspergillus oryzae69.060.0 582
LLPS-Asf-0225Aspergillus flavus69.060.0 582
LLPS-Scj-0627Schizosaccharomyces japonicus57.974e-158 471
LLPS-Usm-0200Ustilago maydis57.798e-152 456
LLPS-Scc-0597Schizosaccharomyces cryophilus57.477e-157 468
LLPS-Scp-0485Schizosaccharomyces pombe57.222e-155 464
LLPS-Spr-1159Sporisorium reilianum57.143e-149 449
LLPS-Crn-1580Cryptococcus neoformans54.719e-146 439
LLPS-Miv-0073Microbotryum violaceum54.414e-145 439
LLPS-Pug-0543Puccinia graminis53.622e-145 440
LLPS-Put-1256Puccinia triticina52.629e-126 384
LLPS-Zem-0300Zea mays51.572e-118 370
LLPS-Sob-2536Sorghum bicolor51.053e-118 370
LLPS-Abg-0977Absidia glauca50.982e-138 422
LLPS-Mel-1160Melampsora laricipopulina50.715e-142 432
LLPS-Sei-2512Setaria italica50.655e-118 369
LLPS-Brd-1599Brachypodium distachyon50.522e-117 367
LLPS-Dac-2313Daucus carota50.522e-118 369
LLPS-Lep-1032Leersia perrieri50.268e-119 371
LLPS-Gor-2060Gossypium raimondii50.266e-121 376
LLPS-Art-2168Arabidopsis thaliana50.261e-118 370
LLPS-Mae-0920Manihot esculenta50.263e-120 374
LLPS-Arl-1845Arabidopsis lyrata50.08e-119 371
LLPS-Phv-0543Phaseolus vulgaris50.08e-119 370
LLPS-Orgl-1154Oryza glumaepatula49.873e-118 369
LLPS-Orb-1996Oryza barthii49.873e-118 369
LLPS-Ori-1561Oryza indica49.873e-118 369
LLPS-Orni-1287Oryza nivara49.873e-118 369
LLPS-Orm-0984Oryza meridionalis49.873e-118 369
LLPS-Orr-1504Oryza rufipogon49.873e-118 369
LLPS-Org-2176Oryza glaberrima49.873e-118 369
LLPS-Ors-2150Oryza sativa49.873e-118 369
LLPS-Orp-1597Oryza punctata49.874e-118 369
LLPS-Orbr-1877Oryza brachyantha49.875e-116 358
LLPS-Vir-0815Vigna radiata49.744e-118 369
LLPS-Glm-1550Glycine max49.742e-118 369
LLPS-Sem-1792Selaginella moellendorffii49.742e-118 367
LLPS-Thc-2431Theobroma cacao49.743e-118 369
LLPS-Viv-1605Vitis vinifera49.744e-119 371
LLPS-Sot-1983Solanum tuberosum49.485e-119 371
LLPS-Sol-0114Solanum lycopersicum49.487e-119 371
LLPS-Nia-2380Nicotiana attenuata49.481e-118 370
LLPS-Via-2135Vigna angularis49.462e-115 355
LLPS-Amt-2061Amborella trichopoda49.354e-115 360
LLPS-Cus-0362Cucumis sativus49.216e-117 365
LLPS-Tra-2851Triticum aestivum49.213e-115 362
LLPS-Hea-2399Helianthus annuus49.212e-115 361
LLPS-Coc-1094Corchorus capsularis49.212e-118 370
LLPS-Pot-2623Populus trichocarpa49.214e-117 366
LLPS-Met-1922Medicago truncatula48.951e-115 362
LLPS-Brn-0441Brassica napus48.835e-114 358
LLPS-Bro-1749Brassica oleracea48.834e-114 359
LLPS-Brr-1662Brassica rapa48.835e-114 358
LLPS-Hov-1957Hordeum vulgare48.712e-115 362
LLPS-Prp-2201Prunus persica48.692e-116 364
LLPS-Tru-0395Triticum urartu48.458e-112 362
LLPS-Lac-3153Latimeria chalumnae48.055e-114 357
LLPS-Dar-3011Danio rerio47.791e-110 349
LLPS-Asm-0924Astyanax mexicanus47.671e-109 346
LLPS-Tar-2499Takifugu rubripes47.276e-109 345
LLPS-Scf-2046Scleropages formosus47.273e-109 345
LLPS-Anc-1118Anolis carolinensis47.181e-111 351
LLPS-Loa-4471Loxodonta africana47.185e-112 352
LLPS-Pes-2903Pelodiscus sinensis47.183e-111 350
LLPS-Ten-0898Tetraodon nigroviridis47.158e-108 341
LLPS-Pof-0288Poecilia formosa47.152e-108 343
LLPS-Xim-2863Xiphophorus maculatus47.012e-108 344
LLPS-Php-2446Physcomitrella patens46.974e-114 358
LLPS-Dio-2482Dipodomys ordii46.921e-111 351
LLPS-Bot-3680Bos taurus46.922e-111 351
LLPS-Ran-1225Rattus norvegicus46.922e-111 350
LLPS-Paa-1460Papio anubis46.922e-111 351
LLPS-Mal-4410Mandrillus leucophaeus46.922e-111 351
LLPS-Aim-2630Ailuropoda melanoleuca46.921e-111 351
LLPS-Ova-0807Ovis aries46.922e-111 351
LLPS-Myl-2186Myotis lucifugus46.922e-111 351
LLPS-Mea-3783Mesocricetus auratus46.922e-111 350
LLPS-Maf-3286Macaca fascicularis46.922e-111 351
LLPS-Mum-3657Mus musculus46.922e-111 350
LLPS-Chs-1975Chlorocebus sabaeus46.921e-111 351
LLPS-Aon-0903Aotus nancymaae46.922e-111 351
LLPS-Sah-2261Sarcophilus harrisii46.927e-111 349
LLPS-Cea-4551Cercocebus atys46.922e-111 351
LLPS-Sus-1625Sus scrofa46.921e-111 351
LLPS-Gog-4141Gorilla gorilla46.922e-111 351
LLPS-Fud-2154Fukomys damarensis46.921e-111 351
LLPS-Caj-4346Callithrix jacchus46.922e-111 351
LLPS-Caf-2014Canis familiaris46.921e-111 351
LLPS-Cap-0095Cavia porcellus46.926e-111 350
LLPS-Mam-3381Macaca mulatta46.922e-111 351
LLPS-Cas-3181Carlito syrichta46.922e-111 351
LLPS-Ict-3086Ictidomys tridecemlineatus46.921e-111 351
LLPS-Nol-2364Nomascus leucogenys46.922e-111 351
LLPS-Pat-4780Pan troglodytes46.922e-111 351
LLPS-Pap-3608Pan paniscus46.922e-111 351
LLPS-Urm-3810Ursus maritimus46.921e-111 351
LLPS-Hos-1129Homo sapiens46.922e-111 351
LLPS-Fec-1161Felis catus46.921e-111 351
LLPS-Man-1486Macaca nemestrina46.922e-111 351
LLPS-Otg-1742Otolemur garnettii46.922e-111 351
LLPS-Orc-1553Oryctolagus cuniculus46.922e-111 351
LLPS-Rhb-4374Rhinopithecus bieti46.922e-111 351
LLPS-Meg-1230Meleagris gallopavo46.96e-34 135
LLPS-Cii-1655Ciona intestinalis46.796e-110 347
LLPS-Eqc-1780Equus caballus46.675e-111 349
LLPS-Orl-1024Oryzias latipes46.659e-109 344
LLPS-Leo-3409Lepisosteus oculatus46.467e-25 105
LLPS-Cis-0512Ciona savignyi46.418e-110 347
LLPS-Drm-0623Drosophila melanogaster46.151e-112 354
LLPS-Tut-2382Tursiops truncatus46.157e-106 336
LLPS-Mod-3739Monodelphis domestica46.155e-109 344
LLPS-Xet-0896Xenopus tropicalis45.451e-108 343
LLPS-Gas-0815Galdieria sulphuraria44.224e-100 321
LLPS-Mup-2657Mustela putorius furo43.52e-43 166
LLPS-Chc-0718Chondrus crispus43.323e-84 279
LLPS-Cae-1655Caenorhabditis elegans43.224e-93 303
LLPS-Mua-0097Musa acuminata41.353e-86 283
LLPS-Poa-1913Pongo abelii41.282e-82 274
LLPS-Chr-0650Chlamydomonas reinhardtii41.122e-89 293
LLPS-Orn-0224Oreochromis niloticus40.842e-115 361
LLPS-Ora-0494Ornithorhynchus anatinus40.755e-80 268
LLPS-Gaga-1637Gallus gallus40.556e-117 365
LLPS-Fia-2479Ficedula albicollis40.556e-117 365
LLPS-Scm-0385Scophthalmus maximus40.486e-114 357
LLPS-Tag-3257Taeniopygia guttata40.371e-115 362
LLPS-Icp-1986Ictalurus punctatus40.252e-113 356
LLPS-Yal-0966Yarrowia lipolytica40.073e-123 380
LLPS-Gaa-2485Gasterosteus aculeatus39.631e-112 353
LLPS-Kop-1473Komagataella pastoris39.186e-88 289
LLPS-Osl-0456Ostreococcus lucimarinus38.863e-79 262
LLPS-Anp-2996Anas platyrhynchos36.332e-91 298
LLPS-Cym-1142Cyanidioschyzon merolae32.533e-56 206