• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Brn-1658
BnaA06g10940D

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Inosine-5'-monophosphate dehydrogenase
Gene Name: BnaA06g10940D, GSBRNA2T00057955001
Ensembl Gene: GSBRNA2T00148102001
Ensembl Protein: CDX88544
Organism: Brassica napus
Taxa ID: 3708
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblCDX88544CDX88544
UniProtA0A078HCA2, A0A078HCA2_BRANA
GeneBankLK032346CDY35084.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MTSLEDGFPA  EKLFSQGYSY  TYDDVIFLPH  YIDFSTDAVS  LSTRLSRRVP  LSIPCVSSPM  60
61    DTVSESHMAA  AMASLGGIGI  VHYNSDIAAQ  ASVIRQAKSL  RHPIASDAGV  KLPEYEITSL  120
121   DAFGPSSFVF  VTQSGTMTVP  KLLGYVTKAQ  WKKMNYEQRE  MKIYDYMKSC  EGSEYCLPWD  180
181   IDIEKIEALL  EDKQKGFVVL  ERDGETVNVV  TRDDIERVRG  YPKSGPGTVG  LDGEWMVGAA  240
241   IGTRESDKER  LEHLVKAGAN  VVVLDSSQGN  SIYQLEMIKY  VKKSYPELDV  IGGNVVTSYQ  300
301   AQNLIQAGVD  GLRVGMGSGS  ICTTQEVCAV  GRGQATAVYK  VCSLAAQSGI  PVIADGGISN  360
361   SGHIVKALVL  GASTVMMGSF  LAGSTEAPGS  YEYKNGKRIK  KYRGMGSLEA  MTKGSDQRYL  420
421   GDKTNLKIAQ  GVVGAVADKG  SVLKLIPYTM  HAVKQGFQDL  GASSLQSAHD  LLRSNVLRLE  480
481   TRTGAAQIEG  GVHGLVSYEK  KSF  503
Nucleotide CDS Sequence (FASTA)
1     ATGACGTCTC  TCGAAGATGG  TTTCCCGGCG  GAGAAGCTCT  TCTCTCAGGG  ATACTCCTAC  60
61    ACCTACGACG  ACGTCATCTT  CCTCCCTCAC  TACATCGACT  TCTCCACCGA  CGCCGTCTCC  120
121   CTCTCCACGC  GACTCAGCCG  GCGCGTGCCC  CTCTCCATCC  CCTGCGTCTC  CTCTCCGATG  180
181   GACACCGTCT  CAGAGTCTCA  CATGGCCGCC  GCGATGGCCT  CCCTCGGCGG  GATCGGGATC  240
241   GTCCATTACA  ACTCCGACAT  CGCCGCTCAG  GCGTCGGTGA  TCCGACAAGC  CAAGTCGCTG  300
301   CGTCATCCGA  TCGCTTCCGA  CGCCGGCGTG  AAGCTCCCGG  AGTACGAGAT  CACTTCGTTG  360
361   GACGCCTTTG  GTCCTTCCTC  CTTCGTCTTC  GTCACGCAAT  CAGGAACAAT  GACGGTTCCG  420
421   AAGCTGTTAG  GCTACGTCAC  GAAAGCTCAG  TGGAAAAAGA  TGAACTACGA  GCAAAGAGAG  480
481   ATGAAGATAT  ATGATTACAT  GAAGAGCTGT  GAAGGCAGCG  AGTATTGTCT  ACCATGGGAC  540
541   ATTGACATTG  AAAAGATCGA  AGCTTTGTTA  GAAGATAAGC  AAAAGGGCTT  TGTGGTTCTC  600
601   GAAAGGGACG  GTGAGACTGT  GAATGTTGTG  ACGAGAGACG  ACATAGAGAG  GGTCAGAGGG  660
661   TATCCCAAGT  CAGGGCCAGG  GACTGTTGGT  TTAGACGGGG  AGTGGATGGT  TGGTGCGGCG  720
721   ATAGGGACGA  GGGAGTCCGA  TAAGGAGAGG  CTGGAGCATT  TGGTTAAAGC  TGGGGCTAAT  780
781   GTTGTGGTGT  TGGATAGTTC  TCAAGGGAAC  TCTATTTACC  AGCTTGAGAT  GATTAAGTAT  840
841   GTGAAGAAGA  GTTATCCTGA  GTTGGATGTG  ATTGGTGGAA  ACGTTGTGAC  GAGTTACCAG  900
901   GCGCAGAACT  TGATTCAAGC  TGGAGTTGAT  GGGTTGAGAG  TTGGTATGGG  GTCTGGTTCG  960
961   ATTTGTACCA  CACAAGAGGT  TTGCGCGGTT  GGTCGTGGAC  AGGCTACTGC  TGTGTACAAG  1020
1021  GTTTGTTCAC  TCGCTGCTCA  GAGTGGGATT  CCGGTTATAG  CGGATGGTGG  TATCTCAAAC  1080
1081  TCAGGTCACA  TTGTAAAAGC  TCTAGTACTC  GGAGCATCAA  CTGTTATGAT  GGGAAGCTTC  1140
1141  TTAGCCGGAA  GCACTGAGGC  TCCTGGGTCT  TACGAGTATA  AGAATGGTAA  GAGGATCAAG  1200
1201  AAGTACCGTG  GAATGGGATC  GCTAGAAGCA  ATGACAAAAG  GAAGTGATCA  GAGATACTTA  1260
1261  GGAGACAAAA  CAAATCTCAA  GATTGCTCAA  GGAGTGGTTG  GTGCAGTGGC  TGATAAAGGA  1320
1321  TCAGTGTTGA  AGCTGATTCC  TTACACAATG  CACGCGGTGA  AGCAAGGTTT  TCAAGACCTT  1380
1381  GGTGCTTCTT  CCTTGCAATC  TGCTCATGAT  CTGTTGAGAT  CTAACGTCCT  CAGGCTCGAG  1440
1441  ACTCGAACCG  GTGCAGCACA  GATCGAAGGT  GGAGTTCACG  GTCTTGTTTC  TTATGAGAAG  1500
1501  AAATCATTTT  AA  1512

▼ KEYWORD

ID
Family
Coiled coil
Complete proteome
Cytoplasm
GMP biosynthesis
Metal-binding
NAD
Oxidoreductase
Potassium
Purine biosynthesis
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Molecular Function
IMP dehydrogenase activity
Molecular Function
Metal ion binding
Molecular Function
Nucleotide binding
Biological Process
GMP biosynthetic process

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Bro-1412Brassica oleracea100.00.01031
LLPS-Brr-2408Brassica rapa98.810.01024
LLPS-Arl-0147Arabidopsis lyrata91.650.0 951
LLPS-Art-1382Arabidopsis thaliana91.450.0 962
LLPS-Thc-1411Theobroma cacao75.850.0 739
LLPS-Gor-1048Gossypium raimondii75.40.0 758
LLPS-Tru-1749Triticum urartu75.03e-149 439
LLPS-Coc-1687Corchorus capsularis74.80.0 740
LLPS-Sem-2172Selaginella moellendorffii74.284e-139 414
LLPS-Pot-1500Populus trichocarpa73.120.0 717
LLPS-Glm-2946Glycine max72.060.0 696
LLPS-Prp-2478Prunus persica71.860.0 716
LLPS-Mae-2041Manihot esculenta71.310.0 715
LLPS-Phv-0678Phaseolus vulgaris70.660.0 692
LLPS-Via-0475Vigna angularis70.660.0 698
LLPS-Viv-0614Vitis vinifera70.60.0 672
LLPS-Cus-1084Cucumis sativus70.460.0 723
LLPS-Met-0026Medicago truncatula70.320.0 706
LLPS-Dac-1684Daucus carota69.580.0 698
LLPS-Sot-1900Solanum tuberosum69.060.0 685
LLPS-Sol-1041Solanum lycopersicum68.460.0 678
LLPS-Nia-0587Nicotiana attenuata68.390.0 684
LLPS-Mua-2443Musa acuminata67.660.0 673
LLPS-Vir-1499Vigna radiata67.60.0 644
LLPS-Tra-0216Triticum aestivum65.540.0 634
LLPS-Sei-0343Setaria italica65.420.0 621
LLPS-Org-1496Oryza glaberrima65.40.0 624
LLPS-Sob-1270Sorghum bicolor65.40.0 617
LLPS-Orp-1928Oryza punctata65.40.0 623
LLPS-Orbr-2163Oryza brachyantha65.280.0 616
LLPS-Orm-0602Oryza meridionalis65.20.0 619
LLPS-Orr-0835Oryza rufipogon65.20.0 623
LLPS-Orni-1065Oryza nivara65.20.0 623
LLPS-Hov-1155Hordeum vulgare65.080.0 634
LLPS-Zem-0780Zea mays65.00.0 604
LLPS-Lep-1656Leersia perrieri64.80.0 610
LLPS-Brd-1981Brachypodium distachyon64.60.0 607
LLPS-Ors-1156Oryza sativa64.150.0 578
LLPS-Amt-2341Amborella trichopoda62.180.0 611
LLPS-Ori-2103Oryza indica60.370.0 603
LLPS-Php-1610Physcomitrella patens57.850.0 557
LLPS-Asn-1194Aspergillus nidulans55.791e-99 309
LLPS-Chr-0294Chlamydomonas reinhardtii49.612e-154 457
LLPS-Cii-2005Ciona intestinalis48.941e-109 338
LLPS-Drm-2362Drosophila melanogaster48.244e-150 447
LLPS-Orc-3916Oryctolagus cuniculus48.121e-148 442
LLPS-Meg-3337Meleagris gallopavo47.873e-134 404
LLPS-Ten-2052Tetraodon nigroviridis47.838e-150 447
LLPS-Nol-2537Nomascus leucogenys47.723e-150 447
LLPS-Ere-0480Erinaceus europaeus47.726e-151 449
LLPS-Gaa-1905Gasterosteus aculeatus47.631e-149 446
LLPS-Icp-1661Ictalurus punctatus47.611e-146 441
LLPS-Cas-1262Carlito syrichta47.521e-149 445
LLPS-Poa-1510Pongo abelii47.522e-149 445
LLPS-Otg-4452Otolemur garnettii47.525e-150 446
LLPS-Man-3472Macaca nemestrina47.522e-149 445
LLPS-Loa-2952Loxodonta africana47.521e-148 442
LLPS-Pap-4652Pan paniscus47.523e-149 444
LLPS-Pat-0353Pan troglodytes47.523e-149 444
LLPS-Hos-2963Homo sapiens47.523e-149 444
LLPS-Mod-1573Monodelphis domestica47.524e-150 446
LLPS-Fec-4086Felis catus47.522e-149 444
LLPS-Mal-4014Mandrillus leucophaeus47.521e-149 445
LLPS-Aim-1379Ailuropoda melanoleuca47.524e-149 444
LLPS-Ran-1891Rattus norvegicus47.523e-149 444
LLPS-Dio-2098Dipodomys ordii47.522e-149 445
LLPS-Tut-1963Tursiops truncatus47.527e-149 443
LLPS-Caj-3657Callithrix jacchus47.522e-149 445
LLPS-Gog-3571Gorilla gorilla47.523e-149 444
LLPS-Cea-3370Cercocebus atys47.521e-149 445
LLPS-Maf-3593Macaca fascicularis47.521e-149 445
LLPS-Chs-4463Chlorocebus sabaeus47.521e-149 445
LLPS-Orn-3216Oreochromis niloticus47.435e-150 447
LLPS-Mup-1939Mustela putorius furo47.436e-149 446
LLPS-Bot-2386Bos taurus47.435e-149 446
LLPS-Orl-1912Oryzias latipes47.436e-148 444
LLPS-Sus-4230Sus scrofa47.434e-149 446
LLPS-Eqc-2573Equus caballus47.332e-148 444
LLPS-Cap-4421Cavia porcellus47.337e-149 443
LLPS-Rhb-1813Rhinopithecus bieti47.334e-148 441
LLPS-Myl-3325Myotis lucifugus47.333e-149 444
LLPS-Ova-1936Ovis aries47.331e-147 440
LLPS-Fud-3363Fukomys damarensis47.337e-149 443
LLPS-Scm-0704Scophthalmus maximus47.242e-147 443
LLPS-Ora-1639Ornithorhynchus anatinus47.244e-144 430
LLPS-Xet-1886Xenopus tropicalis47.27e-146 436
LLPS-Pof-3852Poecilia formosa47.151e-146 439
LLPS-Tag-2241Taeniopygia guttata47.133e-140 421
LLPS-Mum-4373Mus musculus47.135e-148 441
LLPS-Caf-3929Canis familiaris47.098e-143 428
LLPS-Scf-3575Scleropages formosus47.046e-143 441
LLPS-Mam-1098Macaca mulatta46.976e-147 438
LLPS-Paa-4246Papio anubis46.976e-147 438
LLPS-Leo-0021Lepisosteus oculatus46.952e-144 436
LLPS-Dar-1093Danio rerio46.941e-148 444
LLPS-Sah-3301Sarcophilus harrisii46.942e-142 429
LLPS-Mea-0572Mesocricetus auratus46.935e-147 438
LLPS-Xim-4119Xiphophorus maculatus46.852e-147 440
LLPS-Anc-3648Anolis carolinensis46.783e-131 399
LLPS-Asm-2637Astyanax mexicanus46.762e-147 443
LLPS-Chc-0907Chondrus crispus46.753e-143 429
LLPS-Mel-1002Melampsora laricipopulina46.685e-140 421
LLPS-Lac-3283Latimeria chalumnae46.522e-139 419
LLPS-Cym-0707Cyanidioschyzon merolae46.323e-143 430
LLPS-Tar-1055Takifugu rubripes46.251e-145 436
LLPS-Gaga-3548Gallus gallus45.752e-144 432
LLPS-Yal-1185Yarrowia lipolytica45.662e-133 404
LLPS-Urm-2015Ursus maritimus45.371e-143 431
LLPS-Aon-3984Aotus nancymaae45.371e-143 431
LLPS-Ict-1434Ictidomys tridecemlineatus44.993e-142 427
LLPS-Fia-3852Ficedula albicollis44.941e-121 372
LLPS-Crn-1469Cryptococcus neoformans44.867e-133 403
LLPS-Abg-0843Absidia glauca44.831e-139 420
LLPS-Miv-0947Microbotryum violaceum44.551e-135 410
LLPS-Map-1261Magnaporthe poae44.551e-124 382
LLPS-Gas-0386Galdieria sulphuraria44.473e-138 416
LLPS-Anp-1202Anas platyrhynchos44.371e-113 350
LLPS-Sac-0949Saccharomyces cerevisiae44.197e-136 410
LLPS-Ved-1272Verticillium dahliae44.053e-123 378
LLPS-Mao-0089Magnaporthe oryzae44.052e-121 374
LLPS-Gag-0551Gaeumannomyces graminis43.893e-124 381
LLPS-Ast-1484Aspergillus terreus43.871e-128 392
LLPS-Nec-1177Neurospora crassa43.877e-128 390
LLPS-Cog-1015Colletotrichum gloeosporioides43.851e-121 374
LLPS-Zyt-0349Zymoseptoria tritici43.811e-129 395
LLPS-Usm-1282Ustilago maydis43.84e-133 404
LLPS-Spr-0999Sporisorium reilianum43.742e-132 402
LLPS-Asg-0453Ashbya gossypii43.691e-131 399
LLPS-Pug-1147Puccinia graminis43.651e-133 405
LLPS-Pes-1464Pelodiscus sinensis43.615e-113 350
LLPS-Nef-1260Neosartorya fischeri43.496e-123 377
LLPS-Asf-0995Aspergillus flavus43.325e-125 383
LLPS-Aso-1291Aspergillus oryzae43.325e-125 383
LLPS-Asni-0780Aspergillus niger43.15e-127 388
LLPS-Lem-1293Leptosphaeria maculans43.062e-125 384
LLPS-Fus-0898Fusarium solani43.01e-120 371
LLPS-Beb-1173Beauveria bassiana42.972e-117 363
LLPS-Cogr-0871Colletotrichum graminicola42.831e-122 377
LLPS-Fuo-1028Fusarium oxysporum42.833e-118 365
LLPS-Fuv-0743Fusarium verticillioides42.833e-118 365
LLPS-Dos-1395Dothistroma septosporum42.555e-123 378
LLPS-Pyt-1585Pyrenophora teres42.466e-121 372
LLPS-Put-0803Puccinia triticina42.362e-108 338
LLPS-Pytr-1585Pyrenophora triticirepentis42.263e-120 371
LLPS-Coo-1623Colletotrichum orbiculare42.242e-119 369
LLPS-Scs-0688Sclerotinia sclerotiorum42.131e-122 377
LLPS-Blg-1418Blumeria graminis42.032e-120 371
LLPS-Trv-0093Trichoderma virens41.871e-116 361
LLPS-Trr-1016Trichoderma reesei41.851e-117 364
LLPS-Scp-1424Schizosaccharomyces pombe41.674e-123 377
LLPS-Scc-0322Schizosaccharomyces cryophilus41.596e-125 382
LLPS-Phn-0109Phaeosphaeria nodorum41.525e-117 362
LLPS-Tum-0212Tuber melanosporum41.414e-124 380
LLPS-Scj-1026Schizosaccharomyces japonicus41.332e-119 368
LLPS-Cis-0076Ciona savignyi36.71e-92 300