LLPS-Zem-1630
ZEAMMB73_Zm00001d005238
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Eukaryotic translation initiation factor 3 subunit E |
| Gene Name: | ZEAMMB73_Zm00001d005238 |
| Ensembl Gene: | Zm00001d005238 |
| Ensembl Protein: | Zm00001d005238_P005 |
| Organism: | Zea mays |
| Taxa ID: | 4577 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus, Stress granule | Predicted from orthologs | (View) |
▼ FUNCTION
| Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | Zm00001d005238_T005 | Zm00001d005238_P005 |
| Ensembl | Zm00001d005238_T004 | Zm00001d005238_P004 |
| Ensembl | Zm00001d005238_T002 | Zm00001d005238_P002 |
| Ensembl | Zm00001d005238_T001 | Zm00001d005238_P001 |
| Ensembl | Zm00001d005238_T003 | Zm00001d005238_P003 |
| UniProt | C0P7L2, C0P7L2_MAIZE | |
| GeneBank | BT064281, CM007648 | ACN28978.1, ONM20649.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSEHDLTALM AAQLDRHLVF PLLEFLQERQ LYSESEILEA KIRLLSGTNM VDYAMDIHKS 60 61 LYGTDDVPED MVKRRAEVVS RLRSLEEAAA PLVAFLQNPQ LVQEFRPDKQ YNIHMLQERY 120 121 QIGPDQIEAL YQYAKFQFEC GNYSGAADYL YQYRALCTNS ERNVSALWGK LAAEILMQNW 180 181 DVALEELNRL KEIIDSKNFS SPLNQLQNRI WLMHWALFIF FNHENGRNGI IDLFFQDRYL 240 241 NAIQTNAHHL IRYLATAVVV NKRRRNMLKE LIKVIQQEHH SYKDPVTEFL ECLYVNYDFD 300 301 GAQQKLIECE QVILNDPFLG KRIEEGNFVS VPLRDEFLEN ARLFIFETYC RIHRCIDISM 360 361 LAQKLNMSYD EAELWIMNLV RSSKLDARID SVSGTLIMTT NHVNVHEQIV ESLKGLNMRT 420 421 YMLAKNIVEP AQQATR 436 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTCGGAGC ACGACCTCAC GGCGCTGATG GCGGCGCAGC TGGACCGCCA CCTGGTGTTC 60 61 CCCCTGCTGG AGTTCCTCCA GGAGCGGCAG CTCTACTCGG AGTCGGAGAT CCTGGAGGCC 120 121 AAGATCCGCC TCCTCAGCGG CACCAACATG GTCGACTACG CCATGGACAT CCACAAGTCC 180 181 CTCTACGGCA CCGACGACGT GCCCGAGGAC ATGGTGAAGC GCCGCGCCGA GGTCGTCTCC 240 241 AGGCTCAGGT CGCTCGAGGA GGCCGCAGCC CCGCTCGTCG CCTTCCTCCA GAACCCGCAG 300 301 CTCGTGCAGG AGTTCAGGCC CGACAAACAG TACAACATCC ACATGCTCCA GGAGCGATAC 360 361 CAGATCGGTC CTGACCAGAT TGAAGCTCTG TATCAGTATG CCAAATTTCA GTTTGAGTGT 420 421 GGTAACTACT CAGGGGCTGC TGATTACCTT TACCAGTATC GTGCTTTGTG CACAAACAGT 480 481 GAGCGAAATG TGAGTGCCCT CTGGGGAAAG CTGGCAGCAG AAATCCTAAT GCAGAACTGG 540 541 GACGTAGCTT TGGAGGAACT CAACCGCTTG AAGGAAATAA TTGATTCAAA GAACTTCTCA 600 601 TCACCTCTGA ATCAGCTCCA GAACAGGATA TGGCTGATGC ATTGGGCTCT GTTCATCTTC 660 661 TTTAACCATG AAAATGGTAG AAATGGGATC ATTGATCTGT TCTTCCAGGA CAGGTACTTG 720 721 AATGCTATAC AGACAAATGC ACACCATCTT ATTAGGTATC TAGCTACTGC AGTTGTTGTC 780 781 AACAAAAGGA GAAGGAATAT GCTTAAAGAG TTGATTAAGG TCATTCAACA GGAGCACCAT 840 841 AGCTACAAGG ATCCCGTAAC TGAATTTCTG GAATGCTTAT ATGTTAACTA TGATTTTGAT 900 901 GGTGCTCAAC AGAAACTCAT AGAGTGTGAG CAGGTTATAC TGAATGATCC ATTCCTGGGA 960 961 AAGCGCATTG AAGAGGGAAA TTTTGTCAGT GTTCCTTTGA GAGATGAGTT CCTTGAAAAT 1020 1021 GCTAGGCTTT TTATTTTCGA GACATACTGC CGTATCCATC GGTGCATCGA TATCAGCATG 1080 1081 CTTGCTCAGA AGTTGAACAT GAGCTACGAT GAGGCCGAGT TGTGGATCAT GAATTTGGTT 1140 1141 AGAAGCTCAA AACTGGATGC CAGGATCGAT TCAGTATCAG GAACTCTCAT CATGACAACC 1200 1201 AATCACGTCA ATGTCCATGA GCAGATTGTT GAGAGCTTGA AGGGCCTTAA TATGAGGACC 1260 1261 TACATGCTCG CAAAGAACAT CGTTGAGCCA GCTCAGCAGG CAACTCGGTG A 1311 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Eukaryotic 43S preinitiation complex | |
Cellular Component | Eukaryotic 48S preinitiation complex | |
Cellular Component | Eukaryotic translation initiation factor 3 complex | |
Cellular Component | Eukaryotic translation initiation factor 3 complex, eIF3e | |
Cellular Component | Nucleus | |
Molecular Function | Translation initiation factor activity | |
Biological Process | Formation of cytoplasmic translation initiation complex | |
Biological Process | Translational initiation |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Sob-2292 | Sorghum bicolor | 96.13 | 0.0 | 881 |
| LLPS-Sei-1634 | Setaria italica | 94.76 | 0.0 | 870 |
| LLPS-Orp-1552 | Oryza punctata | 87.91 | 0.0 | 808 |
| LLPS-Ori-1726 | Oryza indica | 87.91 | 0.0 | 807 |
| LLPS-Orni-0395 | Oryza nivara | 87.91 | 0.0 | 808 |
| LLPS-Orgl-0784 | Oryza glumaepatula | 87.91 | 0.0 | 807 |
| LLPS-Orbr-1555 | Oryza brachyantha | 87.7 | 0.0 | 816 |
| LLPS-Ors-1131 | Oryza sativa | 87.67 | 0.0 | 806 |
| LLPS-Orr-0331 | Oryza rufipogon | 87.67 | 0.0 | 806 |
| LLPS-Org-0590 | Oryza glaberrima | 87.67 | 0.0 | 806 |
| LLPS-Orb-0408 | Oryza barthii | 87.67 | 0.0 | 806 |
| LLPS-Brd-2276 | Brachypodium distachyon | 87.27 | 0.0 | 816 |
| LLPS-Lep-1643 | Leersia perrieri | 87.24 | 0.0 | 808 |
| LLPS-Orm-1128 | Oryza meridionalis | 82.46 | 0.0 | 732 |
| LLPS-Mua-1130 | Musa acuminata | 81.59 | 0.0 | 762 |
| LLPS-Tru-1299 | Triticum urartu | 81.31 | 0.0 | 738 |
| LLPS-Tra-1807 | Triticum aestivum | 80.95 | 0.0 | 754 |
| LLPS-Hov-0330 | Hordeum vulgare | 80.05 | 0.0 | 747 |
| LLPS-Amt-0389 | Amborella trichopoda | 79.68 | 0.0 | 754 |
| LLPS-Glm-0251 | Glycine max | 76.89 | 0.0 | 709 |
| LLPS-Via-1571 | Vigna angularis | 76.66 | 0.0 | 705 |
| LLPS-Phv-1685 | Phaseolus vulgaris | 76.43 | 0.0 | 706 |
| LLPS-Prp-0610 | Prunus persica | 75.69 | 0.0 | 701 |
| LLPS-Dac-0605 | Daucus carota | 75.29 | 0.0 | 695 |
| LLPS-Cus-1444 | Cucumis sativus | 75.29 | 0.0 | 702 |
| LLPS-Met-2253 | Medicago truncatula | 75.29 | 0.0 | 700 |
| LLPS-Gor-2005 | Gossypium raimondii | 75.0 | 0.0 | 695 |
| LLPS-Arl-1172 | Arabidopsis lyrata | 74.88 | 0.0 | 693 |
| LLPS-Coc-1431 | Corchorus capsularis | 74.83 | 0.0 | 700 |
| LLPS-Php-1738 | Physcomitrella patens | 74.77 | 0.0 | 697 |
| LLPS-Art-0514 | Arabidopsis thaliana | 74.19 | 0.0 | 694 |
| LLPS-Viv-1090 | Vitis vinifera | 74.14 | 0.0 | 696 |
| LLPS-Thc-1850 | Theobroma cacao | 73.84 | 0.0 | 682 |
| LLPS-Bro-2638 | Brassica oleracea | 73.73 | 0.0 | 688 |
| LLPS-Brn-0213 | Brassica napus | 73.73 | 0.0 | 687 |
| LLPS-Pot-1422 | Populus trichocarpa | 73.68 | 0.0 | 687 |
| LLPS-Mae-0118 | Manihot esculenta | 73.68 | 0.0 | 687 |
| LLPS-Nia-1167 | Nicotiana attenuata | 73.62 | 0.0 | 682 |
| LLPS-Brr-1984 | Brassica rapa | 73.5 | 0.0 | 686 |
| LLPS-Hea-1754 | Helianthus annuus | 73.23 | 0.0 | 688 |
| LLPS-Sol-1322 | Solanum lycopersicum | 73.09 | 0.0 | 671 |
| LLPS-Sot-0524 | Solanum tuberosum | 73.09 | 0.0 | 669 |
| LLPS-Vir-1245 | Vigna radiata | 69.79 | 0.0 | 624 |
| LLPS-Sem-0787 | Selaginella moellendorffii | 63.95 | 0.0 | 585 |
| LLPS-Chr-1697 | Chlamydomonas reinhardtii | 56.15 | 2e-175 | 505 |
| LLPS-Myl-1257 | Myotis lucifugus | 53.27 | 3e-168 | 488 |
| LLPS-Leo-0285 | Lepisosteus oculatus | 53.23 | 9e-167 | 484 |
| LLPS-Urm-2276 | Ursus maritimus | 53.05 | 1e-167 | 486 |
| LLPS-Pat-0851 | Pan troglodytes | 53.05 | 4e-167 | 486 |
| LLPS-Hos-0975 | Homo sapiens | 53.05 | 1e-167 | 486 |
| LLPS-Man-3648 | Macaca nemestrina | 53.05 | 5e-167 | 486 |
| LLPS-Loa-0336 | Loxodonta africana | 53.05 | 8e-168 | 486 |
| LLPS-Otg-0113 | Otolemur garnettii | 53.05 | 1e-167 | 486 |
| LLPS-Orc-0560 | Oryctolagus cuniculus | 53.05 | 2e-167 | 486 |
| LLPS-Caf-2977 | Canis familiaris | 53.05 | 1e-167 | 486 |
| LLPS-Poa-2585 | Pongo abelii | 53.05 | 1e-167 | 486 |
| LLPS-Eqc-3206 | Equus caballus | 53.05 | 1e-167 | 486 |
| LLPS-Cap-1000 | Cavia porcellus | 53.05 | 1e-167 | 486 |
| LLPS-Cas-0337 | Carlito syrichta | 53.05 | 1e-167 | 486 |
| LLPS-Ict-2861 | Ictidomys tridecemlineatus | 53.05 | 1e-167 | 486 |
| LLPS-Nol-0308 | Nomascus leucogenys | 53.05 | 2e-167 | 486 |
| LLPS-Mea-1193 | Mesocricetus auratus | 53.05 | 1e-167 | 486 |
| LLPS-Mum-3244 | Mus musculus | 53.05 | 1e-167 | 486 |
| LLPS-Chs-2306 | Chlorocebus sabaeus | 53.05 | 1e-167 | 486 |
| LLPS-Aon-3178 | Aotus nancymaae | 53.05 | 1e-167 | 487 |
| LLPS-Cea-0656 | Cercocebus atys | 53.05 | 5e-167 | 486 |
| LLPS-Sah-0761 | Sarcophilus harrisii | 53.05 | 3e-168 | 487 |
| LLPS-Sus-1884 | Sus scrofa | 53.05 | 1e-167 | 486 |
| LLPS-Gog-1470 | Gorilla gorilla | 53.05 | 1e-167 | 486 |
| LLPS-Fud-1996 | Fukomys damarensis | 53.05 | 5e-168 | 487 |
| LLPS-Caj-1851 | Callithrix jacchus | 53.05 | 2e-167 | 486 |
| LLPS-Tut-1262 | Tursiops truncatus | 53.05 | 1e-167 | 486 |
| LLPS-Dio-3881 | Dipodomys ordii | 53.05 | 1e-167 | 486 |
| LLPS-Bot-2536 | Bos taurus | 53.05 | 2e-167 | 487 |
| LLPS-Ran-0642 | Rattus norvegicus | 53.05 | 1e-167 | 486 |
| LLPS-Paa-2566 | Papio anubis | 53.05 | 7e-167 | 486 |
| LLPS-Mal-2391 | Mandrillus leucophaeus | 53.05 | 1e-167 | 486 |
| LLPS-Ova-1735 | Ovis aries | 53.05 | 1e-167 | 486 |
| LLPS-Aim-4127 | Ailuropoda melanoleuca | 53.05 | 1e-167 | 486 |
| LLPS-Mup-0832 | Mustela putorius furo | 53.05 | 1e-167 | 486 |
| LLPS-Anc-0178 | Anolis carolinensis | 52.76 | 2e-163 | 475 |
| LLPS-Meg-1489 | Meleagris gallopavo | 52.6 | 1e-166 | 483 |
| LLPS-Lac-3327 | Latimeria chalumnae | 52.6 | 2e-167 | 486 |
| LLPS-Fia-1025 | Ficedula albicollis | 52.6 | 1e-166 | 483 |
| LLPS-Ora-2314 | Ornithorhynchus anatinus | 52.54 | 1e-146 | 431 |
| LLPS-Orn-2279 | Oreochromis niloticus | 52.53 | 2e-165 | 480 |
| LLPS-Rhb-2534 | Rhinopithecus bieti | 52.49 | 8e-165 | 479 |
| LLPS-Pes-1943 | Pelodiscus sinensis | 52.37 | 4e-165 | 481 |
| LLPS-Xim-1166 | Xiphophorus maculatus | 52.37 | 4e-168 | 487 |
| LLPS-Cii-0261 | Ciona intestinalis | 52.31 | 5e-158 | 461 |
| LLPS-Scm-2845 | Scophthalmus maximus | 52.3 | 5e-164 | 477 |
| LLPS-Pof-0940 | Poecilia formosa | 52.14 | 1e-167 | 486 |
| LLPS-Mod-0686 | Monodelphis domestica | 52.14 | 7e-164 | 476 |
| LLPS-Tar-2697 | Takifugu rubripes | 52.14 | 6e-166 | 483 |
| LLPS-Tag-0123 | Taeniopygia guttata | 51.93 | 4e-153 | 448 |
| LLPS-Ten-2233 | Tetraodon nigroviridis | 51.92 | 7e-166 | 481 |
| LLPS-Dar-3547 | Danio rerio | 51.69 | 8e-165 | 479 |
| LLPS-Asm-0076 | Astyanax mexicanus | 51.69 | 7e-166 | 481 |
| LLPS-Xet-2289 | Xenopus tropicalis | 51.58 | 8e-163 | 474 |
| LLPS-Icp-1034 | Ictalurus punctatus | 51.47 | 5e-165 | 479 |
| LLPS-Scf-2756 | Scleropages formosus | 51.35 | 1e-159 | 466 |
| LLPS-Gaa-3010 | Gasterosteus aculeatus | 51.24 | 3e-165 | 480 |
| LLPS-Gaga-3007 | Gallus gallus | 50.87 | 1e-163 | 476 |
| LLPS-Anp-1973 | Anas platyrhynchos | 50.79 | 4e-157 | 459 |
| LLPS-Orl-2298 | Oryzias latipes | 50.79 | 7e-163 | 474 |
| LLPS-Mam-3956 | Macaca mulatta | 50.65 | 9e-162 | 474 |
| LLPS-Maf-3049 | Macaca fascicularis | 50.65 | 9e-162 | 474 |
| LLPS-Gas-0689 | Galdieria sulphuraria | 50.12 | 4e-155 | 454 |
| LLPS-Fec-0170 | Felis catus | 49.89 | 5e-162 | 473 |
| LLPS-Chc-0625 | Chondrus crispus | 48.74 | 4e-139 | 414 |
| LLPS-Cis-1860 | Ciona savignyi | 47.3 | 6e-139 | 413 |
| LLPS-Drm-0276 | Drosophila melanogaster | 47.26 | 6e-138 | 410 |
| LLPS-Abg-1819 | Absidia glauca | 45.75 | 7e-149 | 437 |
| LLPS-Pap-0921 | Pan paniscus | 45.57 | 3e-41 | 150 |
| LLPS-Scp-1264 | Schizosaccharomyces pombe | 44.19 | 3e-103 | 323 |
| LLPS-Scc-0582 | Schizosaccharomyces cryophilus | 43.93 | 1e-100 | 316 |
| LLPS-Scj-0810 | Schizosaccharomyces japonicus | 43.38 | 1e-99 | 315 |
| LLPS-Asc-0093 | Aspergillus clavatus | 42.56 | 3e-126 | 380 |
| LLPS-Nef-0374 | Neosartorya fischeri | 42.33 | 8e-125 | 377 |
| LLPS-Cae-0889 | Caenorhabditis elegans | 42.03 | 1e-112 | 345 |
| LLPS-Asfu-1365 | Aspergillus fumigatus | 41.97 | 4e-126 | 380 |
| LLPS-Ast-0414 | Aspergillus terreus | 41.63 | 1e-122 | 371 |
| LLPS-Asni-0403 | Aspergillus niger | 41.51 | 2e-123 | 374 |
| LLPS-Asn-0787 | Aspergillus nidulans | 41.4 | 5e-121 | 367 |
| LLPS-Coo-0310 | Colletotrichum orbiculare | 41.16 | 1e-110 | 340 |
| LLPS-Aso-0014 | Aspergillus oryzae | 41.06 | 7e-123 | 372 |
| LLPS-Asf-0391 | Aspergillus flavus | 41.06 | 7e-123 | 372 |
| LLPS-Put-1004 | Puccinia triticina | 40.61 | 2e-74 | 241 |
| LLPS-Osl-0632 | Ostreococcus lucimarinus | 40.42 | 1e-107 | 332 |
| LLPS-Cogr-0308 | Colletotrichum graminicola | 40.32 | 1e-110 | 340 |
| LLPS-Cog-0331 | Colletotrichum gloeosporioides | 40.23 | 1e-109 | 337 |
| LLPS-Miv-0178 | Microbotryum violaceum | 40.05 | 2e-114 | 352 |
| LLPS-Dos-0819 | Dothistroma septosporum | 40.0 | 8e-116 | 354 |
| LLPS-Fuo-1477 | Fusarium oxysporum | 39.67 | 2e-106 | 329 |
| LLPS-Ved-1234 | Verticillium dahliae | 39.67 | 2e-105 | 327 |
| LLPS-Tum-0331 | Tuber melanosporum | 39.64 | 4e-39 | 145 |
| LLPS-Lem-0677 | Leptosphaeria maculans | 39.63 | 3e-116 | 354 |
| LLPS-Pyt-0116 | Pyrenophora teres | 39.63 | 8e-116 | 353 |
| LLPS-Fus-1507 | Fusarium solani | 39.53 | 7e-107 | 330 |
| LLPS-Mel-0452 | Melampsora laricipopulina | 39.52 | 2e-105 | 326 |
| LLPS-Map-0890 | Magnaporthe poae | 39.46 | 3e-115 | 352 |
| LLPS-Fuv-1049 | Fusarium verticillioides | 39.44 | 7e-106 | 328 |
| LLPS-Pug-0386 | Puccinia graminis | 39.4 | 7e-109 | 337 |
| LLPS-Pytr-0122 | Pyrenophora triticirepentis | 39.4 | 5e-115 | 351 |
| LLPS-Yal-0722 | Yarrowia lipolytica | 39.29 | 3e-111 | 341 |
| LLPS-Blg-0126 | Blumeria graminis | 38.99 | 1e-112 | 345 |
| LLPS-Phn-0171 | Phaeosphaeria nodorum | 38.65 | 2e-104 | 323 |
| LLPS-Crn-0627 | Cryptococcus neoformans | 38.44 | 9e-101 | 315 |
| LLPS-Trr-1214 | Trichoderma reesei | 38.26 | 1e-101 | 317 |
| LLPS-Trv-0839 | Trichoderma virens | 38.26 | 2e-101 | 316 |
| LLPS-Beb-1068 | Beauveria bassiana | 38.25 | 1e-103 | 322 |
| LLPS-Mao-0125 | Magnaporthe oryzae | 38.2 | 5e-115 | 351 |
| LLPS-Gag-0583 | Gaeumannomyces graminis | 38.12 | 2e-112 | 345 |
| LLPS-Nec-1322 | Neurospora crassa | 37.44 | 3e-108 | 334 |
| LLPS-Zyt-0642 | Zymoseptoria tritici | 37.27 | 3e-107 | 331 |
| LLPS-Usm-0565 | Ustilago maydis | 34.11 | 9e-95 | 302 |
| LLPS-Spr-0564 | Sporisorium reilianum | 34.03 | 6e-95 | 303 |
| LLPS-Kop-0645 | Komagataella pastoris | 33.49 | 5e-77 | 253 |
| LLPS-Cym-0734 | Cyanidioschyzon merolae | 31.9 | 1e-71 | 242 |