LLPS-Xim-1508
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Telomeric repeat-binding factor |
| Ensembl Gene: | ENSXMAG00000020978.1 |
| Ensembl Protein: | ENSXMAP00000027475.1 |
| Organism: | Xiphophorus maculatus |
| Taxa ID: | 8083 |
| LLPS Type: | LLPS regulator |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| PML nuclear body | Predicted from orthologs | (View) |
▼ FUNCTION
| Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSXMAT00000023867.1 | ENSXMAP00000027475.1 |
| UniProt | A0A3B5Q8U7, A0A3B5Q8U7_XIPMA | |
| RefSeq | XM_005797919.2 | XP_005797976.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MECEIKEELA SKSSSTDDSV SFPHVTAVAS GWMLDFMFVS LCRSFKEGNF DEFNETLSVF 60 61 EALFQSKSLK ADAHNEKSLI CAFLARVMHG KHLDVLFEKD EHVMPLMSAA TVWSSLENVV 120 121 EDEGLFKEIT ILLFVQAVAV CLEKGQRSSA SSVLKWFEKR HTCPRNLGIK LSTIVTKADT 180 181 YHPVIMSFSY NRLLETIHSF LDNYLKKNPC DFLLKTATGF VQSSRNMLDS EPVELQDSTV 240 241 SEKQSETTQK NKKTKRKLLS TKLTEAWSPD TTKKLFVSLT RLSGSEVCHL TARKNVETST 300 301 LQNSEKYMEK KTRKKWTAQL DKYLRDGVKR HGQGNWSRIL LDYDFEGRTG TMLKDRWRVL 360 361 LRNHKVG 367 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGAGTGTG AAATTAAAGA GGAACTCGCC TCAAAGTCAT CGAGTACAGA TGATAGTGTC 60 61 AGCTTTCCTC ATGTCACCGC CGTCGCCTCA GGATGGATGC TGGACTTCAT GTTTGTGAGT 120 121 TTATGTCGAA GCTTCAAAGA AGGAAACTTT GATGAATTTA ACGAAACTCT GTCCGTTTTT 180 181 GAAGCTCTTT TTCAGAGTAA ATCTCTTAAA GCAGATGCCC ATAATGAAAA ATCCTTGATA 240 241 TGTGCGTTTC TAGCAAGAGT AATGCACGGA AAGCACCTGG ATGTCCTGTT TGAAAAAGAT 300 301 GAACATGTAA TGCCTCTGAT GTCTGCTGCC ACTGTTTGGT CGAGCCTGGA AAACGTAGTG 360 361 GAAGATGAAG GCTTATTCAA AGAGATTACC ATTCTCCTGT TTGTCCAGGC TGTGGCCGTC 420 421 TGCCTGGAGA AAGGCCAGAG GTCTTCTGCC TCCTCGGTCC TCAAGTGGTT TGAAAAAAGA 480 481 CACACATGCC CTCGGAACTT GGGAATTAAA CTCTCGACTA TCGTCACAAA AGCTGATACG 540 541 TACCACCCAG TAATCATGAG CTTCAGCTAC AACCGCCTCC TGGAGACCAT ACACTCCTTC 600 601 TTGGATAACT ACTTGAAAAA GAATCCATGT GATTTCCTCC TCAAGACAGC TACAGGTTTT 660 661 GTCCAATCTT CCCGAAACAT GCTGGATTCG GAGCCTGTGG AGTTACAAGA CAGCACTGTC 720 721 TCAGAAAAGC AAAGTGAAAC AACACAGAAG AATAAAAAAA CAAAACGCAA ACTGCTCTCT 780 781 ACTAAACTTA CCGAGGCATG GTCACCTGAT ACCACGAAAA AGCTGTTTGT TTCTCTGACG 840 841 CGACTCTCTG GCAGTGAGGT GTGTCACCTG ACGGCGAGGA AGAACGTAGA AACCTCCACA 900 901 TTGCAAAATA GTGAAAAGTA CATGGAAAAG AAAACACGAA AGAAATGGAC TGCCCAGCTG 960 961 GACAAATACC TTCGGGACGG GGTCAAACGT CACGGGCAGG GGAACTGGTC TCGAATCTTA 1020 1021 CTGGATTATG ACTTTGAGGG ACGCACTGGC ACCATGCTGA AAGACCGCTG GAGAGTTCTG 1080 1081 CTAAGGAATC ACAAAGTCGG CTGA 1104 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Nuclear chromosome, telomeric region | |
Molecular Function | Double-stranded telomeric DNA binding | |
Molecular Function | Protein homodimerization activity | |
Biological Process | Cell cycle | |
Biological Process | Telomere maintenance |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Orn-3252 | Oreochromis niloticus | 59.56 | 1e-85 | 272 |
| LLPS-Gaa-1980 | Gasterosteus aculeatus | 58.38 | 3e-50 | 172 |
| LLPS-Otg-2298 | Otolemur garnettii | 55.36 | 3e-10 | 65.5 |
| LLPS-Tar-2600 | Takifugu rubripes | 55.26 | 2e-120 | 359 |
| LLPS-Scm-2908 | Scophthalmus maximus | 54.79 | 4e-133 | 392 |
| LLPS-Orl-1567 | Oryzias latipes | 52.08 | 1e-08 | 61.2 |
| LLPS-Scf-2015 | Scleropages formosus | 50.0 | 1e-08 | 60.5 |
| LLPS-Mum-2953 | Mus musculus | 48.0 | 2e-08 | 60.1 |
| LLPS-Anc-0835 | Anolis carolinensis | 47.92 | 4e-09 | 62.4 |
| LLPS-Tut-1305 | Tursiops truncatus | 46.15 | 3e-08 | 59.7 |
| LLPS-Sus-2357 | Sus scrofa | 46.15 | 4e-08 | 58.9 |
| LLPS-Dio-2997 | Dipodomys ordii | 46.0 | 1e-07 | 57.8 |
| LLPS-Fud-3158 | Fukomys damarensis | 46.0 | 5e-08 | 58.5 |
| LLPS-Fec-2845 | Felis catus | 46.0 | 1e-07 | 57.8 |
| LLPS-Pof-2341 | Poecilia formosa | 44.12 | 2e-07 | 57.0 |
| LLPS-Anp-1253 | Anas platyrhynchos | 44.0 | 8e-10 | 64.3 |
| LLPS-Ran-2845 | Rattus norvegicus | 43.75 | 6e-08 | 58.2 |
| LLPS-Ora-0747 | Ornithorhynchus anatinus | 43.75 | 2e-07 | 56.2 |
| LLPS-Sah-2088 | Sarcophilus harrisii | 43.75 | 4e-08 | 58.9 |
| LLPS-Xet-1615 | Xenopus tropicalis | 43.75 | 6e-08 | 58.2 |
| LLPS-Pes-3155 | Pelodiscus sinensis | 43.75 | 2e-08 | 59.7 |
| LLPS-Mod-3482 | Monodelphis domestica | 43.75 | 4e-08 | 58.9 |
| LLPS-Leo-1296 | Lepisosteus oculatus | 43.48 | 8e-07 | 55.1 |
| LLPS-Paa-2691 | Papio anubis | 42.55 | 3e-07 | 56.6 |
| LLPS-Aon-1120 | Aotus nancymaae | 42.55 | 3e-07 | 56.2 |
| LLPS-Orc-0515 | Oryctolagus cuniculus | 42.55 | 2e-07 | 57.0 |
| LLPS-Dar-0854 | Danio rerio | 42.42 | 4e-09 | 62.4 |
| LLPS-Cis-1702 | Ciona savignyi | 42.11 | 4e-07 | 53.5 |
| LLPS-Ova-4190 | Ovis aries | 42.0 | 3e-08 | 59.3 |
| LLPS-Myl-0584 | Myotis lucifugus | 42.0 | 1e-07 | 57.8 |
| LLPS-Aim-0697 | Ailuropoda melanoleuca | 42.0 | 3e-08 | 59.3 |
| LLPS-Mup-3531 | Mustela putorius furo | 42.0 | 2e-08 | 59.7 |
| LLPS-Mal-4264 | Mandrillus leucophaeus | 42.0 | 3e-08 | 59.3 |
| LLPS-Bot-1012 | Bos taurus | 42.0 | 5e-08 | 58.9 |
| LLPS-Gog-0601 | Gorilla gorilla | 42.0 | 5e-08 | 58.5 |
| LLPS-Caj-1412 | Callithrix jacchus | 42.0 | 5e-08 | 58.9 |
| LLPS-Chs-1601 | Chlorocebus sabaeus | 42.0 | 3e-08 | 59.3 |
| LLPS-Maf-2728 | Macaca fascicularis | 42.0 | 5e-08 | 58.9 |
| LLPS-Cea-1787 | Cercocebus atys | 42.0 | 5e-08 | 58.9 |
| LLPS-Nol-1345 | Nomascus leucogenys | 42.0 | 5e-08 | 58.5 |
| LLPS-Eqc-2415 | Equus caballus | 42.0 | 4e-08 | 58.9 |
| LLPS-Poa-2571 | Pongo abelii | 42.0 | 4e-08 | 58.9 |
| LLPS-Mam-1653 | Macaca mulatta | 42.0 | 5e-08 | 58.9 |
| LLPS-Rhb-3777 | Rhinopithecus bieti | 42.0 | 4e-08 | 58.5 |
| LLPS-Hos-2125 | Homo sapiens | 42.0 | 5e-08 | 58.9 |
| LLPS-Pap-1524 | Pan paniscus | 42.0 | 3e-08 | 59.3 |
| LLPS-Urm-2433 | Ursus maritimus | 42.0 | 3e-08 | 59.3 |
| LLPS-Pat-1768 | Pan troglodytes | 42.0 | 5e-08 | 58.9 |
| LLPS-Man-3524 | Macaca nemestrina | 42.0 | 5e-08 | 58.5 |
| LLPS-Tag-0551 | Taeniopygia guttata | 41.94 | 4e-09 | 62.0 |
| LLPS-Asm-1327 | Astyanax mexicanus | 41.67 | 4e-06 | 52.8 |
| LLPS-Ict-3331 | Ictidomys tridecemlineatus | 41.67 | 2e-07 | 56.6 |
| LLPS-Caf-4256 | Canis familiaris | 41.67 | 7e-08 | 58.2 |
| LLPS-Lac-0283 | Latimeria chalumnae | 41.67 | 1e-06 | 54.7 |
| LLPS-Gaga-0102 | Gallus gallus | 41.54 | 1e-07 | 57.8 |
| LLPS-Icp-2675 | Ictalurus punctatus | 41.18 | 7e-08 | 58.5 |
| LLPS-Hea-0113 | Helianthus annuus | 38.46 | 3e-06 | 52.8 |
| LLPS-Mea-2149 | Mesocricetus auratus | 37.93 | 2e-07 | 56.6 |
| LLPS-Glm-2452 | Glycine max | 37.66 | 3e-06 | 52.8 |
| LLPS-Cap-2187 | Cavia porcellus | 36.92 | 2e-07 | 56.6 |
| LLPS-Fia-1087 | Ficedula albicollis | 36.51 | 4e-09 | 62.4 |
| LLPS-Lep-2240 | Leersia perrieri | 35.71 | 1e-07 | 56.6 |
| LLPS-Loa-3164 | Loxodonta africana | 35.54 | 5e-54 | 190 |
| LLPS-Sei-1941 | Setaria italica | 35.06 | 9e-07 | 55.1 |
| LLPS-Cas-0181 | Carlito syrichta | 33.87 | 6e-39 | 148 |
| LLPS-Meg-1994 | Meleagris gallopavo | 32.52 | 9e-42 | 156 |