• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Xet-3933
cct5

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: T-complex protein 1 subunit epsilon
Gene Name: cct5
Ensembl Gene: ENSXETG00000013995.3
Ensembl Protein: ENSXETP00000030555.3
Organism: Xenopus tropicalis
Taxa ID: 8364
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ FUNCTION

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSALGTLAFD  EYGRPFIIIK  DQDRKSRLSG  LDALKSHIMA  AKAVANTLRT  SLGPNGLDKM  60
61    MVDKDGQVTV  TNDGATILSM  MDVDHQIAKL  MVELSKSQDD  EIGDGTTGVV  VLAGALLEQA  120
121   EQLLDRGIHP  IRIADGYEQA  ARIAVEHLDK  ISDSFPVDPE  NLEPLIRTAM  TTLGSKVINR  180
181   CHRQMAEIAV  NSILTVADMD  RKDVDFELIK  VEGKVGGKLE  DTQLIKGVIV  DKDFSHPQMP  240
241   KVVKDAKIAI  LTCPFEPPKP  KTKHKLDVTS  VEDYKALQKY  EKEKFLEMVK  QIKDTGANLA  300
301   ICQWGFDDEA  NHLLLQNELP  AVRWVGGPEI  ELIAIATGGR  IVPRFCELTP  EKLGYAGIVK  360
361   EISFGTTKDR  MLVIEQCKNS  RAVTIFIRGG  NKMIIEEAKR  SLHDALCVIR  NLVRDNRIVY  420
421   GGGAAEISCA  LAVSEAADKC  PSLEQYAMRA  FADALEIIPM  SLAENSGMNP  IQTMTEVRSK  480
481   QVKESNPALG  IDCLHKGTND  MKQQHVIETL  IGKKQQISLA  TQVVKMILKI  DDIRRPGEIE  540
541   E  541
Nucleotide CDS Sequence (FASTA)
1     ATGTCTGCGC  TTGGAACTCT  CGCCTTCGAT  GAATATGGGC  GGCCTTTTAT  TATCATCAAG  60
61    GACCAGGATC  GCAAGTCTCG  GCTCAGTGGG  CTAGATGCGC  TGAAGTCTCA  TATTATGGCA  120
121   GCTAAAGCCG  TTGCAAACAC  GCTAAGAACA  TCACTTGGGC  CCAATGGACT  TGACAAGATG  180
181   ATGGTGGATA  AGGATGGGCA  AGTTACAGTC  ACCAATGATG  GTGCTACGAT  TCTTAGTATG  240
241   ATGGATGTGG  ATCACCAAAT  TGCCAAACTA  ATGGTTGAAT  TGTCTAAGTC  TCAGGATGAT  300
301   GAAATTGGAG  ATGGCACTAC  AGGTGTTGTA  GTTCTTGCTG  GTGCATTGCT  GGAACAAGCG  360
361   GAACAGTTAT  TAGATCGTGG  TATCCACCCT  ATCAGGATTG  CTGATGGGTA  TGAACAAGCA  420
421   GCACGTATTG  CTGTTGAACA  TCTTGACAAG  ATCAGCGACA  GTTTTCCAGT  TGATCCTGAG  480
481   AACTTGGAGC  CACTTATTCG  AACCGCAATG  ACAACATTGG  GCTCAAAAGT  GATCAACCGC  540
541   TGCCACCGAC  AGATGGCAGA  AATTGCAGTG  AATAGCATTT  TGACTGTTGC  TGATATGGAT  600
601   CGCAAGGACG  TAGACTTTGA  GTTAATAAAG  GTTGAAGGAA  AAGTTGGAGG  TAAACTAGAG  660
661   GATACACAAC  TGATCAAAGG  TGTTATAGTG  GACAAGGACT  TCAGTCACCC  TCAGATGCCA  720
721   AAAGTAGTGA  AAGATGCTAA  AATCGCCATT  CTCACATGTC  CATTTGAACC  ACCAAAGCCC  780
781   AAGACAAAAC  ATAAGCTAGA  TGTTACTTCA  GTGGAAGATT  ATAAAGCACT  TCAGAAATAT  840
841   GAGAAAGAAA  AGTTTCTTGA  AATGGTGAAA  CAGATAAAAG  ATACAGGTGC  AAATCTTGCC  900
901   ATATGTCAGT  GGGGCTTTGA  CGATGAAGCA  AATCATTTAT  TATTACAAAA  TGAACTTCCT  960
961   GCTGTTCGAT  GGGTTGGTGG  ACCTGAAATA  GAGTTAATTG  CTATTGCAAC  AGGAGGCCGT  1020
1021  ATTGTCCCAC  GATTTTGTGA  GTTAACTCCA  GAAAAACTTG  GTTATGCTGG  TATTGTGAAA  1080
1081  GAAATTTCTT  TTGGCACAAC  CAAGGATCGA  ATGCTTGTTA  TTGAGCAATG  CAAGAACTCT  1140
1141  AGAGCTGTAA  CTATATTCAT  CAGAGGAGGA  AATAAGATGA  TAATTGAAGA  AGCAAAGCGT  1200
1201  TCACTCCATG  ATGCTTTGTG  TGTTATTCGT  AATCTTGTAA  GGGACAATCG  AATTGTTTAT  1260
1261  GGAGGTGGGG  CTGCAGAGAT  CTCCTGTGCT  TTAGCCGTTA  GCGAGGCTGC  GGACAAGTGT  1320
1321  CCATCTCTGG  AACAGTATGC  CATGAGAGCC  TTTGCTGACG  CATTGGAAAT  TATTCCTATG  1380
1381  TCACTTGCTG  AAAACAGTGG  TATGAATCCT  ATTCAGACAA  TGACTGAAGT  ACGATCTAAG  1440
1441  CAAGTGAAGG  AAAGCAACCC  AGCACTTGGC  ATTGATTGCC  TGCATAAGGG  CACAAATGAT  1500
1501  ATGAAGCAGC  AGCATGTCAT  AGAAACTTTA  ATTGGCAAGA  AACAGCAGAT  TTCTTTGGCT  1560
1561  ACACAAGTTG  TTAAAATGAT  TTTGAAAATC  GATGACATCC  GTCGGCCTGG  TGAAATTGAA  1620
1621  GAGTAA  1626

▼ KEYWORD

ID
Family
ATP-binding
Chaperone
Complete proteome
Cytoplasm
Nucleotide-binding
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Chaperonin-containing T-complex
Molecular Function
ATP binding
Molecular Function
Unfolded protein binding
Biological Process
Protein folding
Biological Process
Skeletal muscle thin filament assembly

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Anp-2626Anas platyrhynchos93.680.0 719
LLPS-Gaga-2446Gallus gallus92.980.01009
LLPS-Fia-2303Ficedula albicollis92.840.0 933
LLPS-Tag-3237Taeniopygia guttata91.870.01001
LLPS-Ora-0647Ornithorhynchus anatinus91.710.0 987
LLPS-Pes-3661Pelodiscus sinensis91.680.0 990
LLPS-Lac-3143Latimeria chalumnae91.50.0 984
LLPS-Scf-1026Scleropages formosus91.50.0 993
LLPS-Asm-2567Astyanax mexicanus91.310.0 988
LLPS-Leo-2140Lepisosteus oculatus91.310.0 993
LLPS-Dar-1195Danio rerio91.130.0 986
LLPS-Orc-3909Oryctolagus cuniculus90.390.0 981
LLPS-Mal-3371Mandrillus leucophaeus90.260.0 907
LLPS-Fec-0996Felis catus90.20.0 980
LLPS-Icp-2007Ictalurus punctatus90.20.0 980
LLPS-Sus-3550Sus scrofa90.20.0 979
LLPS-Loa-4581Loxodonta africana90.020.0 974
LLPS-Urm-0895Ursus maritimus90.020.0 975
LLPS-Anc-1727Anolis carolinensis90.020.0 983
LLPS-Cas-1033Carlito syrichta90.020.0 974
LLPS-Eqc-4555Equus caballus90.020.0 976
LLPS-Aim-3118Ailuropoda melanoleuca90.020.0 975
LLPS-Ova-0380Ovis aries90.020.0 975
LLPS-Rhb-2364Rhinopithecus bieti89.830.0 977
LLPS-Man-3987Macaca nemestrina89.830.0 977
LLPS-Hos-0061Homo sapiens89.830.0 977
LLPS-Pat-3559Pan troglodytes89.830.0 977
LLPS-Pap-1287Pan paniscus89.830.0 977
LLPS-Mod-2713Monodelphis domestica89.830.0 977
LLPS-Ict-3752Ictidomys tridecemlineatus89.830.0 972
LLPS-Mam-0573Macaca mulatta89.830.0 977
LLPS-Gog-0894Gorilla gorilla89.830.0 977
LLPS-Cea-1806Cercocebus atys89.830.0 977
LLPS-Aon-4415Aotus nancymaae89.830.0 976
LLPS-Maf-4546Macaca fascicularis89.830.0 977
LLPS-Mea-4326Mesocricetus auratus89.830.0 974
LLPS-Chs-4721Chlorocebus sabaeus89.830.0 977
LLPS-Paa-1749Papio anubis89.830.0 977
LLPS-Bot-4645Bos taurus89.830.0 975
LLPS-Sah-3716Sarcophilus harrisii89.670.0 967
LLPS-Caj-4510Callithrix jacchus89.650.0 976
LLPS-Mup-1856Mustela putorius furo89.650.0 974
LLPS-Dio-3844Dipodomys ordii89.650.0 974
LLPS-Orn-2557Oreochromis niloticus89.460.0 974
LLPS-Ten-1883Tetraodon nigroviridis89.460.0 975
LLPS-Cap-1488Cavia porcellus89.460.0 974
LLPS-Caf-3585Canis familiaris89.280.0 965
LLPS-Mum-3137Mus musculus89.280.0 967
LLPS-Ran-2298Rattus norvegicus89.280.0 968
LLPS-Meg-0985Meleagris gallopavo89.230.0 867
LLPS-Myl-2982Myotis lucifugus88.910.0 967
LLPS-Xim-3131Xiphophorus maculatus88.910.0 968
LLPS-Poa-1042Pongo abelii88.750.0 957
LLPS-Orl-2258Oryzias latipes88.540.0 966
LLPS-Tar-1345Takifugu rubripes88.540.0 966
LLPS-Pof-3360Poecilia formosa88.170.0 964
LLPS-Scm-2695Scophthalmus maximus87.990.0 959
LLPS-Fud-2439Fukomys damarensis87.990.0 965
LLPS-Gaa-2831Gasterosteus aculeatus87.430.0 955
LLPS-Nol-0132Nomascus leucogenys80.410.0 833
LLPS-Cii-0482Ciona intestinalis79.00.0 875
LLPS-Cis-1930Ciona savignyi77.140.0 862
LLPS-Vir-2085Vigna radiata76.813e-47 176
LLPS-Php-2364Physcomitrella patens73.210.0 780
LLPS-Sot-2002Solanum tuberosum73.187e-137 404
LLPS-Org-1639Oryza glaberrima72.730.0 561
LLPS-Amt-0657Amborella trichopoda72.180.0 765
LLPS-Orbr-2336Oryza brachyantha72.050.0 761
LLPS-Phv-1211Phaseolus vulgaris71.990.0 768
LLPS-Orni-1166Oryza nivara71.990.0 767
LLPS-Abg-1754Absidia glauca71.890.0 793
LLPS-Ors-0679Oryza sativa71.80.0 762
LLPS-Orr-0526Oryza rufipogon71.80.0 762
LLPS-Ori-1881Oryza indica71.80.0 762
LLPS-Glm-1035Glycine max71.80.0 769
LLPS-Via-1472Vigna angularis71.80.0 766
LLPS-Orgl-1116Oryza glumaepatula71.80.0 766
LLPS-Drm-1733Drosophila melanogaster71.610.0 797
LLPS-Mae-2429Manihot esculenta71.430.0 763
LLPS-Met-2137Medicago truncatula71.430.0 759
LLPS-Sei-0789Setaria italica71.430.0 763
LLPS-Nia-0238Nicotiana attenuata71.240.0 764
LLPS-Sol-0415Solanum lycopersicum71.240.0 762
LLPS-Gor-0106Gossypium raimondii71.050.0 764
LLPS-Sem-2251Selaginella moellendorffii71.050.0 761
LLPS-Sob-1795Sorghum bicolor70.860.0 760
LLPS-Thc-1548Theobroma cacao70.860.0 761
LLPS-Cus-1989Cucumis sativus70.860.0 746
LLPS-Bro-0816Brassica oleracea70.780.0 757
LLPS-Brn-1625Brassica napus70.780.0 757
LLPS-Mua-1559Musa acuminata70.750.0 744
LLPS-Brr-2005Brassica rapa70.590.0 755
LLPS-Prp-1545Prunus persica70.540.0 757
LLPS-Tra-2332Triticum aestivum70.490.0 749
LLPS-Dac-2301Daucus carota70.30.0 758
LLPS-Art-2810Arabidopsis thaliana70.210.0 754
LLPS-Pot-2250Populus trichocarpa70.110.0 756
LLPS-Scj-1172Schizosaccharomyces japonicus70.040.0 756
LLPS-Arl-2892Arabidopsis lyrata70.020.0 754
LLPS-Brd-2040Brachypodium distachyon69.980.0 747
LLPS-Fuo-1272Fusarium oxysporum69.830.0 749
LLPS-Fuv-0115Fusarium verticillioides69.830.0 750
LLPS-Map-0892Magnaporthe poae69.660.0 756
LLPS-Fus-0896Fusarium solani69.640.0 749
LLPS-Hea-0661Helianthus annuus69.550.0 748
LLPS-Trv-0168Trichoderma virens69.350.0 748
LLPS-Trr-0674Trichoderma reesei69.290.0 748
LLPS-Gag-1540Gaeumannomyces graminis69.290.0 751
LLPS-Pytr-1537Pyrenophora triticirepentis69.270.0 750
LLPS-Pyt-0001Pyrenophora teres69.270.0 752
LLPS-Scp-0306Schizosaccharomyces pombe69.270.0 754
LLPS-Mel-1167Melampsora laricipopulina69.20.0 744
LLPS-Crn-0491Cryptococcus neoformans69.20.0 761
LLPS-Zem-1631Zea mays69.170.0 753
LLPS-Nef-0262Neosartorya fischeri69.080.0 752
LLPS-Nec-1617Neurospora crassa69.030.0 749
LLPS-Asf-1333Aspergillus flavus68.910.0 749
LLPS-Tum-1483Tuber melanosporum68.890.0 750
LLPS-Cae-0389Caenorhabditis elegans68.870.0 748
LLPS-Aso-1067Aspergillus oryzae68.770.0 743
LLPS-Mao-0868Magnaporthe oryzae68.730.0 751
LLPS-Asfu-0689Aspergillus fumigatus68.580.0 737
LLPS-Scs-0031Sclerotinia sclerotiorum68.550.0 746
LLPS-Cogr-0920Colletotrichum graminicola68.410.0 749
LLPS-Blg-1124Blumeria graminis68.360.0 744
LLPS-Beb-1537Beauveria bassiana68.230.0 748
LLPS-Lem-0812Leptosphaeria maculans68.230.0 741
LLPS-Ast-1060Aspergillus terreus68.190.0 741
LLPS-Cog-1397Colletotrichum gloeosporioides68.10.0 746
LLPS-Ved-0975Verticillium dahliae68.10.0 746
LLPS-Viv-2240Vitis vinifera67.920.0 709
LLPS-Osl-0343Ostreococcus lucimarinus67.730.0 741
LLPS-Asn-1274Aspergillus nidulans67.670.0 743
LLPS-Usm-0948Ustilago maydis67.540.0 745
LLPS-Coo-1453Colletotrichum orbiculare67.480.0 740
LLPS-Zyt-0247Zymoseptoria tritici67.430.0 719
LLPS-Asc-0281Aspergillus clavatus67.350.0 750
LLPS-Put-0424Puccinia triticina67.30.0 731
LLPS-Hov-1556Hordeum vulgare67.145e-131 390
LLPS-Miv-1554Microbotryum violaceum67.110.0 741
LLPS-Pug-0449Puccinia graminis67.110.0 728
LLPS-Orp-0171Oryza punctata67.020.0 747
LLPS-Chr-1722Chlamydomonas reinhardtii66.920.0 733
LLPS-Dos-1599Dothistroma septosporum66.670.0 719
LLPS-Asni-1495Aspergillus niger65.930.0 738
LLPS-Chc-0555Chondrus crispus64.550.0 705
LLPS-Tru-1501Triticum urartu64.170.0 661
LLPS-Asg-0703Ashbya gossypii63.030.0 690
LLPS-Kop-1288Komagataella pastoris60.70.0 676
LLPS-Sac-1413Saccharomyces cerevisiae60.150.0 655
LLPS-Gas-1016Galdieria sulphuraria38.672e-92 299
LLPS-Scc-0091Schizosaccharomyces cryophilus38.144e-90 293