• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Gaa-2831

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: T-complex protein 1 subunit epsilon
Ensembl Gene: ENSGACG00000002643.1
Ensembl Protein: ENSGACP00000003478.1
Organism: Gasterosteus aculeatus
Taxa ID: 69293
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ FUNCTION

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSGACT00000003490.1ENSGACP00000003478.1
UniProtG3NDS8, G3NDS8_GASAC

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSSMGTLAFD  DYGRPFLIIK  DQDKKTRLSG  IDALKSHIMA  GKAVASTLKT  SLGPNGLDKM  60
61    MVDKDGEVTV  TNDGATILGL  MDVEHQIAKL  MVELSKSQDD  EIGDGTTGVV  VLAGALLEQA  120
121   EQLLDRGIHP  IRISDGYDQA  ARVAIEQLDK  IAETLLCDPK  NTEPLIETAM  TTLGSKIINR  180
181   CHRQMAEIAV  NAILTVADME  RKDVDFELIK  MEGKVGGKLE  DTQLIKGVIV  DKEFSHPQMP  240
241   KVLKDVKIAI  LTCPFEPPKP  KTKHKLDVTS  VEDYRALQKY  EKEKFEEMIK  QVKSNGANLA  300
301   ICQWGFDDEA  NHLLLQNELP  AVRWVGGPEI  ELIAIATGGR  IVPRFSELTP  EKLGSAGLVK  360
361   EISFGTTKDH  MLVIQECKNT  RAVTIFIRGG  NKMIIEEAKR  ALHDALCVIR  NLVRDNRIVY  420
421   GGGASEIACA  LAVNQAADKC  PSLEQYAMRA  FADAMEVIPM  ALAENSGFNP  IQTMTEVRAR  480
481   QVKENNPFLG  IDCLHHNTND  MKQQHVVETL  IGKKQQISLA  TQVVRMILKI  DDIRGPGESE  540
541   D  541
Nucleotide CDS Sequence (FASTA)
1     ATGTCCTCCA  TGGGGACACT  CGCTTTTGAT  GACTATGGGA  GGCCTTTTCT  CATCATTAAA  60
61    GACCAGGACA  AGAAGACACG  GCTATCTGGC  ATTGACGCAC  TTAAGTCTCA  TATTATGGCA  120
121   GGCAAGGCAG  TTGCGTCAAC  GCTGAAGACA  TCATTGGGAC  CTAATGGACT  TGACAAGATG  180
181   ATGGTTGACA  AGGATGGCGA  GGTGACCGTC  ACAAATGATG  GAGCCACTAT  TCTCGGCCTG  240
241   ATGGATGTGG  AACATCAGAT  TGCCAAACTC  ATGGTGGAGC  TTTCCAAGTC  CCAGGATGAT  300
301   GAGATTGGTG  ATGGAACCAC  TGGAGTTGTT  GTGCTGGCTG  GGGCTCTACT  TGAGCAGGCC  360
361   GAGCAGCTGC  TGGACCGGGG  AATCCACCCC  ATCAGGATCT  CTGACGGTTA  CGACCAGGCC  420
421   GCACGCGTTG  CCATAGAGCA  GCTTGACAAA  ATTGCTGAAA  CCTTACTGTG  CGATCCCAAA  480
481   AACACAGAAC  CGCTCATTGA  GACCGCCATG  ACAACACTGG  GATCCAAAAT  TATCAACCGG  540
541   TGTCACAGAC  AGATGGCCGA  GATTGCAGTG  AATGCCATCC  TTACAGTGGC  TGACATGGAG  600
601   AGGAAGGATG  TCGACTTTGA  GCTCATCAAG  ATGGAGGGTA  AAGTCGGAGG  CAAGCTGGAG  660
661   GATACACAGC  TCATTAAGGG  AGTCATAGTT  GACAAGGAGT  TCAGCCACCC  TCAGATGCCC  720
721   AAGGTTCTGA  AAGATGTTAA  AATTGCTATC  CTTACCTGCC  CATTTGAGCC  ACCTAAGCCC  780
781   AAGACCAAGC  ATAAGTTGGA  TGTGACCTCT  GTGGAAGACT  ACAGAGCTCT  CCAGAAATAT  840
841   GAAAAGGAGA  AGTTTGAGGA  GATGATCAAA  CAGGTCAAAA  GCAATGGTGC  AAATTTAGCC  900
901   ATTTGCCAGT  GGGGCTTTGA  CGACGAAGCC  AACCACCTTC  TGCTGCAGAA  CGAGCTGCCA  960
961   GCCGTGCGCT  GGGTTGGGGG  GCCAGAGATC  GAGTTGATCG  CCATCGCGAC  AGGAGGCCGC  1020
1021  ATCGTGCCCC  GCTTCTCCGA  GTTGACACCG  GAGAAGCTCG  GCTCAGCTGG  TTTGGTGAAG  1080
1081  GAGATCTCCT  TCGGCACCAC  AAAGGATCAC  ATGTTGGTGA  TCCAGGAGTG  CAAGAACACC  1140
1141  AGGGCGGTAA  CCATTTTCAT  CCGTGGAGGC  AACAAAATGA  TCATTGAGGA  GGCAAAGCGT  1200
1201  GCCCTCCATG  ATGCTCTGTG  TGTAATCCGC  AATTTGGTCA  GAGACAACCG  TATTGTGTAT  1260
1261  GGAGGAGGAG  CTTCAGAGAT  CGCGTGTGCT  CTGGCTGTCA  ACCAGGCTGC  AGATAAGTGC  1320
1321  CCATCACTGG  AGCAGTACGC  CATGAGGGCG  TTCGCTGATG  CTATGGAGGT  TATCCCAATG  1380
1381  GCACTGGCTG  AGAACAGTGG  GTTTAACCCC  ATCCAGACCA  TGACCGAGGT  CCGAGCTAGA  1440
1441  CAGGTCAAGG  AGAACAACCC  CTTCCTCGGC  ATCGACTGTC  TGCACCACAA  CACCAATGAT  1500
1501  ATGAAGCAGC  AGCATGTGGT  GGAGACCCTG  ATTGGAAAGA  AGCAGCAGAT  CTCCCTGGCT  1560
1561  ACTCAGGTCG  TCAGGATGAT  CCTAAAGATC  GACGACATCA  GAGGCCCCGG  GGAGAGCGAG  1620
1621  GACTAA  1626

▼ KEYWORD

ID
Family
ATP-binding
Chaperone
Coiled coil
Complete proteome
Cytoplasm
Nucleotide-binding
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Molecular Function
ATP binding
Molecular Function
Unfolded protein binding
Biological Process
Protein folding
Biological Process
Skeletal muscle thin filament assembly

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Ten-1883Tetraodon nigroviridis94.270.01010
LLPS-Tar-1345Takifugu rubripes93.720.01005
LLPS-Orn-2557Oreochromis niloticus93.160.01006
LLPS-Xim-3131Xiphophorus maculatus92.420.01002
LLPS-Orl-2258Oryzias latipes92.050.01002
LLPS-Scm-2695Scophthalmus maximus91.870.0 991
LLPS-Pof-3360Poecilia formosa91.870.0 995
LLPS-Scf-1026Scleropages formosus91.310.0 986
LLPS-Leo-2140Lepisosteus oculatus90.760.0 983
LLPS-Asm-2567Astyanax mexicanus90.390.0 976
LLPS-Dar-1195Danio rerio90.20.0 976
LLPS-Anp-2626Anas platyrhynchos89.290.0 691
LLPS-Icp-2007Ictalurus punctatus89.090.0 966
LLPS-Lac-3143Latimeria chalumnae88.170.0 947
LLPS-Fia-2303Ficedula albicollis87.480.0 881
LLPS-Xet-3933Xenopus tropicalis87.430.0 954
LLPS-Gaga-2446Gallus gallus87.250.0 954
LLPS-Tag-3237Taeniopygia guttata86.880.0 950
LLPS-Sus-3550Sus scrofa86.880.0 950
LLPS-Mal-3371Mandrillus leucophaeus86.880.0 877
LLPS-Rhb-2364Rhinopithecus bieti86.510.0 946
LLPS-Hos-0061Homo sapiens86.510.0 946
LLPS-Pat-3559Pan troglodytes86.510.0 946
LLPS-Pap-1287Pan paniscus86.510.0 946
LLPS-Man-3987Macaca nemestrina86.510.0 946
LLPS-Mam-0573Macaca mulatta86.510.0 946
LLPS-Gog-0894Gorilla gorilla86.510.0 946
LLPS-Caj-4510Callithrix jacchus86.510.0 946
LLPS-Chs-4721Chlorocebus sabaeus86.510.0 946
LLPS-Maf-4546Macaca fascicularis86.510.0 946
LLPS-Cea-1806Cercocebus atys86.510.0 946
LLPS-Paa-1749Papio anubis86.510.0 946
LLPS-Ora-0647Ornithorhynchus anatinus86.370.0 937
LLPS-Orc-3909Oryctolagus cuniculus86.320.0 945
LLPS-Urm-0895Ursus maritimus86.320.0 944
LLPS-Aon-4415Aotus nancymaae86.320.0 944
LLPS-Aim-3118Ailuropoda melanoleuca86.320.0 944
LLPS-Ova-0380Ovis aries86.320.0 944
LLPS-Fec-0996Felis catus86.140.0 946
LLPS-Eqc-4555Equus caballus86.140.0 942
LLPS-Bot-4645Bos taurus86.140.0 944
LLPS-Nol-0132Nomascus leucogenys86.10.0 758
LLPS-Mod-2713Monodelphis domestica85.950.0 939
LLPS-Cap-1488Cavia porcellus85.950.0 941
LLPS-Mup-1856Mustela putorius furo85.950.0 942
LLPS-Dio-3844Dipodomys ordii85.950.0 942
LLPS-Loa-4581Loxodonta africana85.770.0 940
LLPS-Cas-1033Carlito syrichta85.770.0 939
LLPS-Pes-3661Pelodiscus sinensis85.580.0 934
LLPS-Caf-3585Canis familiaris85.580.0 932
LLPS-Poa-1042Pongo abelii85.420.0 925
LLPS-Sah-3716Sarcophilus harrisii85.420.0 923
LLPS-Ict-3752Ictidomys tridecemlineatus85.210.0 932
LLPS-Myl-2982Myotis lucifugus85.210.0 935
LLPS-Mum-3137Mus musculus85.030.0 930
LLPS-Fud-2439Fukomys damarensis84.840.0 936
LLPS-Ran-2298Rattus norvegicus84.840.0 929
LLPS-Mea-4326Mesocricetus auratus84.660.0 929
LLPS-Anc-1727Anolis carolinensis84.290.0 927
LLPS-Meg-0985Meleagris gallopavo83.940.0 820
LLPS-Cii-0482Ciona intestinalis77.320.0 854
LLPS-Cis-1930Ciona savignyi75.840.0 841
LLPS-Drm-1733Drosophila melanogaster71.720.0 786
LLPS-Vir-2085Vigna radiata71.015e-44 167
LLPS-Abg-1754Absidia glauca70.060.0 773
LLPS-Php-2364Physcomitrella patens70.00.0 752
LLPS-Sot-2002Solanum tuberosum69.353e-132 392
LLPS-Org-1639Oryza glaberrima68.60.0 542
LLPS-Bro-0816Brassica oleracea68.50.0 738
LLPS-Brn-1625Brassica napus68.50.0 738
LLPS-Brr-2005Brassica rapa68.310.0 736
LLPS-Thc-1548Theobroma cacao68.230.0 738
LLPS-Art-2810Arabidopsis thaliana68.120.0 736
LLPS-Nia-0238Nicotiana attenuata68.050.0 737
LLPS-Mae-2429Manihot esculenta68.050.0 736
LLPS-Gor-0106Gossypium raimondii68.050.0 738
LLPS-Sei-0789Setaria italica68.050.0 734
LLPS-Arl-2892Arabidopsis lyrata67.930.0 734
LLPS-Phv-1211Phaseolus vulgaris67.860.0 736
LLPS-Amt-0657Amborella trichopoda67.860.0 729
LLPS-Met-2137Medicago truncatula67.860.0 729
LLPS-Via-1472Vigna angularis67.860.0 736
LLPS-Sob-1795Sorghum bicolor67.670.0 731
LLPS-Glm-1035Glycine max67.670.0 738
LLPS-Sol-0415Solanum lycopersicum67.670.0 734
LLPS-Cus-1989Cucumis sativus67.670.0 721
LLPS-Cae-0389Caenorhabditis elegans67.60.0 735
LLPS-Fuo-1272Fusarium oxysporum67.550.0 726
LLPS-Fuv-0115Fusarium verticillioides67.550.0 726
LLPS-Orbr-2336Oryza brachyantha67.540.0 727
LLPS-Put-0424Puccinia triticina67.490.0 726
LLPS-Crn-0491Cryptococcus neoformans67.490.0 741
LLPS-Orni-1166Oryza nivara67.480.0 733
LLPS-Sem-2251Selaginella moellendorffii67.480.0 733
LLPS-Fus-0896Fusarium solani67.360.0 724
LLPS-Trr-0674Trichoderma reesei67.290.0 732
LLPS-Ors-0679Oryza sativa67.290.0 727
LLPS-Orr-0526Oryza rufipogon67.290.0 727
LLPS-Prp-1545Prunus persica67.290.0 727
LLPS-Ori-1881Oryza indica67.290.0 727
LLPS-Scj-1172Schizosaccharomyces japonicus67.290.0 740
LLPS-Orgl-1116Oryza glumaepatula67.290.0 731
LLPS-Scp-0306Schizosaccharomyces pombe67.290.0 744
LLPS-Map-0892Magnaporthe poae67.230.0 733
LLPS-Pytr-1537Pyrenophora triticirepentis67.180.0 731
LLPS-Mua-1559Musa acuminata67.170.0 716
LLPS-Pug-0449Puccinia graminis67.110.0 723
LLPS-Pot-2250Populus trichocarpa67.110.0 733
LLPS-Mel-1167Melampsora laricipopulina67.110.0 725
LLPS-Tra-2332Triticum aestivum67.110.0 721
LLPS-Asfu-0689Aspergillus fumigatus66.920.0 718
LLPS-Gag-1540Gaeumannomyces graminis66.850.0 728
LLPS-Nef-0262Neosartorya fischeri66.790.0 731
LLPS-Pyt-0001Pyrenophora teres66.790.0 729
LLPS-Usm-0948Ustilago maydis66.730.0 732
LLPS-Asc-0281Aspergillus clavatus66.670.0 737
LLPS-Zem-1631Zea mays66.610.0 729
LLPS-Ast-1060Aspergillus terreus66.480.0 727
LLPS-Nec-1617Neurospora crassa66.480.0 725
LLPS-Trv-0168Trichoderma virens66.420.0 728
LLPS-Scs-0031Sclerotinia sclerotiorum66.420.0 738
LLPS-Hea-0661Helianthus annuus66.350.0 719
LLPS-Brd-2040Brachypodium distachyon66.170.0 714
LLPS-Mao-0868Magnaporthe oryzae66.10.0 726
LLPS-Lem-0812Leptosphaeria maculans66.10.0 723
LLPS-Coo-1453Colletotrichum orbiculare65.980.0 725
LLPS-Dac-2301Daucus carota65.980.0 720
LLPS-Cog-1397Colletotrichum gloeosporioides65.860.0 724
LLPS-Ved-0975Verticillium dahliae65.790.0 724
LLPS-Cogr-0920Colletotrichum graminicola65.790.0 726
LLPS-Osl-0343Ostreococcus lucimarinus65.610.0 724
LLPS-Asn-1274Aspergillus nidulans65.610.0 736
LLPS-Asf-1333Aspergillus flavus65.530.0 727
LLPS-Blg-1124Blumeria graminis65.310.0 727
LLPS-Zyt-0247Zymoseptoria tritici65.290.0 708
LLPS-Aso-1067Aspergillus oryzae65.280.0 721
LLPS-Tum-1483Tuber melanosporum65.190.0 728
LLPS-Dos-1599Dothistroma septosporum65.140.0 707
LLPS-Beb-1537Beauveria bassiana65.130.0 719
LLPS-Miv-1554Microbotryum violaceum64.70.0 728
LLPS-Chr-1722Chlamydomonas reinhardtii64.490.0 707
LLPS-Viv-2240Vitis vinifera64.170.0 677
LLPS-Asni-1495Aspergillus niger63.820.0 724
LLPS-Hov-1556Hordeum vulgare63.572e-126 379
LLPS-Orp-0171Oryza punctata62.810.0 712
LLPS-Chc-0555Chondrus crispus62.50.0 692
LLPS-Asg-0703Ashbya gossypii61.280.0 673
LLPS-Tru-1501Triticum urartu61.090.0 637
LLPS-Kop-1288Komagataella pastoris60.440.0 671
LLPS-Sac-1413Saccharomyces cerevisiae58.610.0 642
LLPS-Gas-1016Galdieria sulphuraria38.13e-89 291