LLPS-Urm-3289
SDHB
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial |
| Gene Name: | SDHB |
| Ensembl Gene: | ENSUMAG00000021415.1 |
| Ensembl Protein: | ENSUMAP00000029595.1 |
| Organism: | Ursus maritimus |
| Taxa ID: | 29073 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus, Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSUMAT00000034966.1 | ENSUMAP00000029595.1 |
| UniProt | A0A384CER2, A0A384CER2_URSMA | |
| RefSeq | , XM_008694678.1 | , XP_008692900.1, XP_008692900.1 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAAVVGVSLK RRFPAAALGG ACLQACRGVQ TAAATAPRIK KFAIYRWDPD KTGDKPRMQT 60 61 YEIDLNKCGP MVLDALIKIK NEIDSTLTFR RSCREGICGS CAMNINGGNT LACTRRIDTN 120 121 LNKVSKIYPL PHMYVIKDLV PDLSNFYAQY KSIEPYLKKK DESQEGKQQY LQSIEDREKL 180 181 DGLYECILCA CCSTSCPSYW WNGDKYLGPA VLMQAYRWMI DSRDDFTEER LAKLQDPFSL 240 241 YRCHTIMNCT RTCPKGLNPG KAIAEIKKMM ATYTGKKASV 280 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCGGCGG TGGTCGGAGT CTCCTTGAAG CGCCGGTTCC CGGCTGCAGC CCTTGGCGGA 60 61 GCCTGCTTGC AGGCCTGCCG GGGAGTGCAG ACAGCTGCCG CCACAGCTCC TCGAATCAAG 120 121 AAATTTGCCA TCTACCGATG GGACCCAGAC AAGACTGGAG ATAAACCTCG TATGCAGACT 180 181 TATGAAATTG ATTTGAATAA ATGTGGTCCT ATGGTGTTGG ATGCTTTAAT CAAGATTAAG 240 241 AATGAAATTG ATTCTACCTT GACCTTCCGA AGATCATGCA GAGAAGGTAT CTGCGGCTCT 300 301 TGTGCCATGA ACATCAACGG AGGTAACACT CTGGCTTGCA CCCGAAGGAT CGACACCAAC 360 361 CTCAACAAAG TCTCCAAAAT CTACCCTCTT CCGCATATGT ATGTGATAAA GGATCTCGTT 420 421 CCCGACTTGA GCAACTTCTA CGCTCAGTAC AAATCCATTG AACCTTATTT GAAGAAGAAG 480 481 GATGAATCCC AGGAGGGCAA GCAGCAGTAT CTGCAGTCCA TAGAAGACCG TGAGAAACTG 540 541 GACGGGCTGT ACGAGTGTAT CCTCTGTGCC TGCTGCAGCA CCAGCTGCCC GAGCTACTGG 600 601 TGGAACGGAG ACAAATACCT GGGGCCTGCC GTTCTTATGC AGGCGTACCG CTGGATGATC 660 661 GACTCGAGAG ATGACTTCAC GGAGGAGCGC CTGGCCAAGC TGCAGGACCC GTTCTCCCTG 720 721 TACCGCTGCC ACACCATCAT GAACTGCACC AGGACCTGCC CCAAGGGGCT GAATCCAGGC 780 781 AAAGCTATTG CTGAAATCAA GAAAATGATG GCCACCTACA CGGGGAAGAA AGCGTCCGTG 840 841 TAA 843 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Mitochondrial inner membrane | |
Molecular Function | 2 iron, 2 sulfur cluster binding | |
Molecular Function | 3 iron, 4 sulfur cluster binding | |
Molecular Function | 4 iron, 4 sulfur cluster binding | |
Molecular Function | Electron transfer activity | |
Molecular Function | Metal ion binding | |
Molecular Function | Succinate dehydrogenase (ubiquinone) activity | |
Biological Process | Tricarboxylic acid cycle |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Caf-1900 | Canis familiaris | 98.57 | 0.0 | 548 |
| LLPS-Mup-3790 | Mustela putorius furo | 98.21 | 0.0 | 538 |
| LLPS-Fec-1174 | Felis catus | 97.49 | 0.0 | 544 |
| LLPS-Myl-4198 | Myotis lucifugus | 95.74 | 8e-133 | 381 |
| LLPS-Eqc-4232 | Equus caballus | 95.71 | 0.0 | 536 |
| LLPS-Sus-4602 | Sus scrofa | 95.71 | 0.0 | 534 |
| LLPS-Cas-0522 | Carlito syrichta | 95.36 | 0.0 | 537 |
| LLPS-Ict-1903 | Ictidomys tridecemlineatus | 95.36 | 0.0 | 536 |
| LLPS-Otg-1032 | Otolemur garnettii | 95.0 | 0.0 | 536 |
| LLPS-Mam-1433 | Macaca mulatta | 95.0 | 0.0 | 525 |
| LLPS-Maf-3260 | Macaca fascicularis | 95.0 | 0.0 | 525 |
| LLPS-Aon-4672 | Aotus nancymaae | 95.0 | 0.0 | 526 |
| LLPS-Pap-0528 | Pan paniscus | 94.64 | 0.0 | 538 |
| LLPS-Pat-3270 | Pan troglodytes | 94.64 | 0.0 | 538 |
| LLPS-Hos-0318 | Homo sapiens | 94.64 | 0.0 | 538 |
| LLPS-Gog-0719 | Gorilla gorilla | 94.64 | 0.0 | 538 |
| LLPS-Caj-4489 | Callithrix jacchus | 94.64 | 0.0 | 526 |
| LLPS-Chs-3312 | Chlorocebus sabaeus | 94.64 | 0.0 | 525 |
| LLPS-Mal-1444 | Mandrillus leucophaeus | 94.64 | 0.0 | 525 |
| LLPS-Mea-2085 | Mesocricetus auratus | 94.6 | 0.0 | 526 |
| LLPS-Poa-1078 | Pongo abelii | 94.29 | 0.0 | 536 |
| LLPS-Aim-0276 | Ailuropoda melanoleuca | 94.29 | 0.0 | 542 |
| LLPS-Bot-1823 | Bos taurus | 94.29 | 0.0 | 522 |
| LLPS-Paa-1141 | Papio anubis | 93.93 | 0.0 | 525 |
| LLPS-Loa-4073 | Loxodonta africana | 93.62 | 0.0 | 530 |
| LLPS-Nol-2522 | Nomascus leucogenys | 93.21 | 0.0 | 521 |
| LLPS-Fud-3211 | Fukomys damarensis | 93.21 | 0.0 | 526 |
| LLPS-Sah-3090 | Sarcophilus harrisii | 92.91 | 1e-176 | 496 |
| LLPS-Cap-1024 | Cavia porcellus | 92.5 | 0.0 | 523 |
| LLPS-Mum-4111 | Mus musculus | 92.5 | 0.0 | 518 |
| LLPS-Ora-1572 | Ornithorhynchus anatinus | 91.71 | 2e-127 | 372 |
| LLPS-Ran-3814 | Rattus norvegicus | 91.43 | 0.0 | 509 |
| LLPS-Dar-1970 | Danio rerio | 90.46 | 3e-167 | 472 |
| LLPS-Dio-1852 | Dipodomys ordii | 90.36 | 2e-180 | 505 |
| LLPS-Anp-2808 | Anas platyrhynchos | 90.16 | 2e-172 | 485 |
| LLPS-Pof-1808 | Poecilia formosa | 89.75 | 1e-168 | 476 |
| LLPS-Asm-0858 | Astyanax mexicanus | 89.34 | 5e-168 | 474 |
| LLPS-Ten-1531 | Tetraodon nigroviridis | 88.89 | 3e-165 | 467 |
| LLPS-Tar-3141 | Takifugu rubripes | 88.89 | 6e-166 | 469 |
| LLPS-Man-4032 | Macaca nemestrina | 88.57 | 2e-169 | 477 |
| LLPS-Xim-0518 | Xiphophorus maculatus | 88.52 | 2e-166 | 470 |
| LLPS-Scm-0542 | Scophthalmus maximus | 88.43 | 1e-163 | 463 |
| LLPS-Mod-0969 | Monodelphis domestica | 88.3 | 0.0 | 513 |
| LLPS-Orn-2350 | Oreochromis niloticus | 87.89 | 1e-170 | 481 |
| LLPS-Orl-1451 | Oryzias latipes | 87.65 | 3e-163 | 462 |
| LLPS-Scf-0122 | Scleropages formosus | 87.65 | 4e-165 | 467 |
| LLPS-Rhb-4064 | Rhinopithecus bieti | 87.5 | 2e-169 | 477 |
| LLPS-Anc-3959 | Anolis carolinensis | 86.78 | 4e-114 | 335 |
| LLPS-Gaa-0709 | Gasterosteus aculeatus | 86.72 | 2e-168 | 475 |
| LLPS-Xet-0091 | Xenopus tropicalis | 83.51 | 1e-170 | 481 |
| LLPS-Gaga-1046 | Gallus gallus | 83.33 | 8e-176 | 494 |
| LLPS-Meg-0423 | Meleagris gallopavo | 82.99 | 5e-176 | 494 |
| LLPS-Ova-1380 | Ovis aries | 82.48 | 6e-158 | 448 |
| LLPS-Fia-2597 | Ficedula albicollis | 81.89 | 3e-150 | 429 |
| LLPS-Icp-2911 | Ictalurus punctatus | 81.88 | 8e-171 | 481 |
| LLPS-Lac-2928 | Latimeria chalumnae | 81.69 | 1e-168 | 476 |
| LLPS-Tag-3068 | Taeniopygia guttata | 81.25 | 7e-143 | 409 |
| LLPS-Cea-3004 | Cercocebus atys | 80.0 | 7e-146 | 417 |
| LLPS-Pes-1955 | Pelodiscus sinensis | 75.34 | 1e-161 | 459 |
| LLPS-Leo-0826 | Lepisosteus oculatus | 74.9 | 7e-131 | 379 |
| LLPS-Abg-1934 | Absidia glauca | 74.89 | 2e-128 | 372 |
| LLPS-Drm-2063 | Drosophila melanogaster | 73.41 | 2e-142 | 410 |
| LLPS-Asg-0373 | Ashbya gossypii | 73.28 | 9e-132 | 381 |
| LLPS-Crn-0670 | Cryptococcus neoformans | 73.26 | 7e-100 | 301 |
| LLPS-Cii-1324 | Ciona intestinalis | 72.95 | 6e-137 | 395 |
| LLPS-Sac-1110 | Saccharomyces cerevisiae | 72.77 | 1e-127 | 371 |
| LLPS-Usm-0325 | Ustilago maydis | 72.61 | 4e-129 | 376 |
| LLPS-Asni-0946 | Aspergillus niger | 72.55 | 1e-51 | 171 |
| LLPS-Cis-1319 | Ciona savignyi | 72.24 | 6e-135 | 390 |
| LLPS-Spr-1375 | Sporisorium reilianum | 71.78 | 7e-127 | 370 |
| LLPS-Fuo-1290 | Fusarium oxysporum | 71.24 | 6e-125 | 364 |
| LLPS-Fuv-0690 | Fusarium verticillioides | 71.24 | 1e-124 | 364 |
| LLPS-Scs-0505 | Sclerotinia sclerotiorum | 71.24 | 1e-123 | 362 |
| LLPS-Put-0877 | Puccinia triticina | 71.02 | 4e-129 | 376 |
| LLPS-Mel-0173 | Melampsora laricipopulina | 70.71 | 1e-127 | 372 |
| LLPS-Kop-1486 | Komagataella pastoris | 70.61 | 2e-128 | 373 |
| LLPS-Dos-0506 | Dothistroma septosporum | 70.51 | 2e-121 | 356 |
| LLPS-Trr-1473 | Trichoderma reesei | 70.45 | 4e-128 | 372 |
| LLPS-Yal-0430 | Yarrowia lipolytica | 70.28 | 3e-127 | 370 |
| LLPS-Gag-0758 | Gaeumannomyces graminis | 70.25 | 5e-126 | 368 |
| LLPS-Nec-1162 | Neurospora crassa | 70.21 | 8e-122 | 357 |
| LLPS-Trv-0433 | Trichoderma virens | 70.08 | 3e-128 | 373 |
| LLPS-Ast-1189 | Aspergillus terreus | 70.04 | 8e-125 | 364 |
| LLPS-Blg-1266 | Blumeria graminis | 69.96 | 1e-124 | 363 |
| LLPS-Amt-1117 | Amborella trichopoda | 69.8 | 2e-101 | 302 |
| LLPS-Asfu-0708 | Aspergillus fumigatus | 69.42 | 2e-127 | 372 |
| LLPS-Scp-0546 | Schizosaccharomyces pombe | 69.23 | 6e-118 | 347 |
| LLPS-Asc-0234 | Aspergillus clavatus | 69.2 | 2e-125 | 367 |
| LLPS-Php-0752 | Physcomitrella patens | 69.07 | 5e-118 | 347 |
| LLPS-Coo-0213 | Colletotrichum orbiculare | 69.04 | 7e-124 | 362 |
| LLPS-Zyt-0254 | Zymoseptoria tritici | 68.91 | 2e-121 | 356 |
| LLPS-Asf-0585 | Aspergillus flavus | 68.78 | 1e-124 | 364 |
| LLPS-Aso-1105 | Aspergillus oryzae | 68.78 | 1e-124 | 364 |
| LLPS-Nef-0315 | Neosartorya fischeri | 68.75 | 8e-126 | 367 |
| LLPS-Ved-0366 | Verticillium dahliae | 68.72 | 5e-123 | 359 |
| LLPS-Scc-1641 | Schizosaccharomyces cryophilus | 68.62 | 9e-116 | 341 |
| LLPS-Beb-1227 | Beauveria bassiana | 68.44 | 2e-124 | 363 |
| LLPS-Phn-1012 | Phaeosphaeria nodorum | 68.38 | 4e-121 | 356 |
| LLPS-Pytr-0573 | Pyrenophora triticirepentis | 68.38 | 2e-120 | 354 |
| LLPS-Lem-1386 | Leptosphaeria maculans | 68.38 | 3e-120 | 353 |
| LLPS-Pyt-0215 | Pyrenophora teres | 68.38 | 4e-120 | 353 |
| LLPS-Cog-1046 | Colletotrichum gloeosporioides | 68.27 | 1e-124 | 363 |
| LLPS-Mao-1450 | Magnaporthe oryzae | 68.16 | 3e-125 | 365 |
| LLPS-Scj-1177 | Schizosaccharomyces japonicus | 68.05 | 4e-120 | 352 |
| LLPS-Miv-1570 | Microbotryum violaceum | 68.0 | 4e-124 | 362 |
| LLPS-Map-0289 | Magnaporthe poae | 67.74 | 5e-125 | 365 |
| LLPS-Cogr-0881 | Colletotrichum graminicola | 67.6 | 1e-124 | 364 |
| LLPS-Asn-0847 | Aspergillus nidulans | 67.35 | 3e-125 | 365 |
| LLPS-Sol-1052 | Solanum lycopersicum | 67.02 | 7e-91 | 276 |
| LLPS-Osl-1325 | Ostreococcus lucimarinus | 66.95 | 1e-119 | 350 |
| LLPS-Mua-2596 | Musa acuminata | 66.83 | 1e-95 | 287 |
| LLPS-Met-0429 | Medicago truncatula | 66.81 | 2e-112 | 333 |
| LLPS-Viv-1033 | Vitis vinifera | 66.67 | 2e-15 | 79.7 |
| LLPS-Bro-0081 | Brassica oleracea | 66.67 | 2e-111 | 330 |
| LLPS-Brn-2333 | Brassica napus | 66.67 | 2e-111 | 330 |
| LLPS-Sot-1698 | Solanum tuberosum | 66.38 | 2e-113 | 335 |
| LLPS-Cae-1541 | Caenorhabditis elegans | 66.12 | 9e-126 | 367 |
| LLPS-Orp-1983 | Oryza punctata | 66.04 | 1e-15 | 79.7 |
| LLPS-Pot-0673 | Populus trichocarpa | 65.98 | 2e-113 | 335 |
| LLPS-Hea-1858 | Helianthus annuus | 65.83 | 2e-105 | 315 |
| LLPS-Cus-0121 | Cucumis sativus | 65.56 | 1e-113 | 336 |
| LLPS-Dac-1628 | Daucus carota | 65.29 | 6e-115 | 339 |
| LLPS-Cym-1036 | Cyanidioschyzon merolae | 65.22 | 4e-108 | 321 |
| LLPS-Hov-1762 | Hordeum vulgare | 65.17 | 1e-83 | 261 |
| LLPS-Mae-1736 | Manihot esculenta | 65.15 | 4e-113 | 335 |
| LLPS-Chr-0935 | Chlamydomonas reinhardtii | 65.13 | 2e-114 | 338 |
| LLPS-Brr-2496 | Brassica rapa | 64.85 | 1e-112 | 333 |
| LLPS-Thc-1512 | Theobroma cacao | 64.83 | 3e-112 | 332 |
| LLPS-Gor-0644 | Gossypium raimondii | 64.75 | 2e-115 | 340 |
| LLPS-Nia-2110 | Nicotiana attenuata | 64.61 | 1e-114 | 338 |
| LLPS-Lep-2144 | Leersia perrieri | 64.61 | 8e-80 | 253 |
| LLPS-Via-0154 | Vigna angularis | 64.17 | 1e-81 | 252 |
| LLPS-Orbr-1288 | Oryza brachyantha | 64.04 | 1e-76 | 245 |
| LLPS-Orr-1243 | Oryza rufipogon | 64.04 | 6e-76 | 244 |
| LLPS-Orni-1681 | Oryza nivara | 64.04 | 6e-76 | 244 |
| LLPS-Ori-2072 | Oryza indica | 64.04 | 6e-76 | 243 |
| LLPS-Brd-1831 | Brachypodium distachyon | 64.04 | 2e-81 | 256 |
| LLPS-Glm-1190 | Glycine max | 63.9 | 2e-111 | 330 |
| LLPS-Vir-0991 | Vigna radiata | 63.9 | 4e-111 | 329 |
| LLPS-Zem-1144 | Zea mays | 63.48 | 2e-80 | 255 |
| LLPS-Art-0705 | Arabidopsis thaliana | 63.16 | 2e-112 | 333 |
| LLPS-Arl-0409 | Arabidopsis lyrata | 63.16 | 3e-112 | 332 |
| LLPS-Sei-1063 | Setaria italica | 63.13 | 2e-79 | 253 |
| LLPS-Prp-0716 | Prunus persica | 62.81 | 9e-109 | 323 |
| LLPS-Fus-0726 | Fusarium solani | 62.13 | 6e-106 | 315 |
| LLPS-Sem-1252 | Selaginella moellendorffii | 61.54 | 2e-107 | 318 |
| LLPS-Tum-0002 | Tuber melanosporum | 61.45 | 4e-105 | 313 |
| LLPS-Coc-0173 | Corchorus capsularis | 60.82 | 1e-102 | 309 |
| LLPS-Tra-2543 | Triticum aestivum | 60.67 | 7e-104 | 312 |
| LLPS-Gas-0647 | Galdieria sulphuraria | 60.64 | 9e-104 | 310 |
| LLPS-Orm-0821 | Oryza meridionalis | 56.22 | 9e-95 | 302 |
| LLPS-Ors-1982 | Oryza sativa | 56.03 | 1e-97 | 296 |
| LLPS-Org-1735 | Oryza glaberrima | 56.03 | 1e-97 | 296 |
| LLPS-Orb-0936 | Oryza barthii | 56.03 | 1e-96 | 301 |
| LLPS-Orgl-1442 | Oryza glumaepatula | 55.6 | 6e-96 | 300 |
| LLPS-Sob-0754 | Sorghum bicolor | 55.42 | 4e-97 | 295 |
| LLPS-Chc-0950 | Chondrus crispus | 50.0 | 3e-28 | 113 |
| LLPS-Tru-1435 | Triticum urartu | 49.79 | 4e-76 | 239 |