LLPS-Rhb-4064
SDHB
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial |
| Gene Name: | SDHB |
| Ensembl Gene: | ENSRBIG00000043434.1 |
| Ensembl Protein: | ENSRBIP00000039986.1 |
| Organism: | Rhinopithecus bieti |
| Taxa ID: | 61621 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus, Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSRBIT00000064015.1 | ENSRBIP00000039986.1 |
| Ensembl | ENSRBIT00000064016.1 | ENSRBIP00000039987.1 |
| UniProt | A0A2K6MW37, A0A2K6MW37_RHIBE |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAAVVALSLR GRLPATTLGA ACLQASRGAQ TAAAAAPRIK KFAIYRWDPD KAGDKPHMQT 60 61 YEVDLNKCGP MVLDALIKIK NEIDSTLTFR RSCREGICGS CAMNINGGNT LACTRRIDTN 120 121 LNKDLSNFYA QYKSIEPYLK KKDESQEGKQ QYLQSIEERE KLDGLYECIL CACCSTSCPS 180 181 YWWNGDKYLG PAVLMQAYRW MIDSRDDFTE ERLAKLQDPF SLYRCHTIMN CTRTCPKGLN 240 241 PGKAIAEIKK MMATYKEKKA SV 262 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCGGCGG TGGTCGCACT CTCCTTGAGG GGCCGGTTAC CGGCCACAAC CCTTGGCGCG 60 61 GCCTGCCTCC AGGCCTCCCG AGGAGCCCAG ACAGCTGCAG CCGCAGCTCC CCGTATCAAG 120 121 AAATTTGCCA TCTATCGATG GGACCCAGAC AAGGCTGGAG ACAAACCTCA TATGCAGACT 180 181 TACGAAGTTG ACCTTAATAA ATGTGGCCCC ATGGTATTGG ATGCTTTAAT CAAGATTAAG 240 241 AATGAAATTG ACTCGACTTT GACCTTCAGA AGATCATGCA GAGAAGGCAT CTGTGGCTCT 300 301 TGTGCAATGA ACATCAATGG AGGCAACACT CTAGCTTGCA CCCGAAGGAT TGACACCAAC 360 361 CTCAATAAGG ATTTGAGCAA CTTCTATGCT CAGTACAAAT CCATTGAGCC TTATTTGAAG 420 421 AAGAAGGATG AATCTCAGGA AGGCAAGCAG CAGTATCTGC AGTCCATAGA AGAGCGTGAG 480 481 AAACTGGACG GGCTCTACGA GTGCATTCTC TGTGCCTGCT GTAGCACCAG CTGCCCCAGC 540 541 TACTGGTGGA ACGGAGACAA ATATCTGGGG CCTGCAGTTC TTATGCAGGC CTATCGCTGG 600 601 ATGATTGACT CCAGAGACGA CTTCACAGAG GAGCGCCTGG CCAAGCTGCA GGACCCGTTC 660 661 TCTCTATACC GCTGCCACAC CATCATGAAC TGCACAAGGA CCTGTCCTAA GGGTCTGAAT 720 721 CCAGGGAAAG CTATTGCGGA AATCAAGAAA ATGATGGCAA CCTATAAGGA GAAGAAAGCT 780 781 TCAGTTTAA 789 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) | |
Cellular Component | Nucleoplasm | |
Cellular Component | Plasma membrane | |
Molecular Function | 2 iron, 2 sulfur cluster binding | |
Molecular Function | 3 iron, 4 sulfur cluster binding | |
Molecular Function | 4 iron, 4 sulfur cluster binding | |
Molecular Function | Electron transfer activity | |
Molecular Function | Metal ion binding | |
Molecular Function | Succinate dehydrogenase (ubiquinone) activity | |
Biological Process | Tricarboxylic acid cycle |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Man-4032 | Macaca nemestrina | 98.85 | 0.0 | 515 |
| LLPS-Paa-1141 | Papio anubis | 92.86 | 2e-180 | 504 |
| LLPS-Mal-1444 | Mandrillus leucophaeus | 92.86 | 1e-180 | 505 |
| LLPS-Chs-3312 | Chlorocebus sabaeus | 92.86 | 1e-180 | 505 |
| LLPS-Mam-1433 | Macaca mulatta | 92.5 | 4e-180 | 504 |
| LLPS-Maf-3260 | Macaca fascicularis | 92.5 | 4e-180 | 504 |
| LLPS-Poa-1078 | Pongo abelii | 92.14 | 3e-180 | 504 |
| LLPS-Pat-3270 | Pan troglodytes | 92.14 | 3e-180 | 504 |
| LLPS-Pap-0528 | Pan paniscus | 92.14 | 3e-180 | 504 |
| LLPS-Hos-0318 | Homo sapiens | 92.14 | 3e-180 | 504 |
| LLPS-Gog-0719 | Gorilla gorilla | 92.14 | 3e-180 | 504 |
| LLPS-Nol-2522 | Nomascus leucogenys | 91.43 | 7e-176 | 493 |
| LLPS-Caj-4489 | Callithrix jacchus | 90.71 | 8e-176 | 493 |
| LLPS-Aon-4672 | Aotus nancymaae | 90.36 | 4e-175 | 491 |
| LLPS-Cas-0522 | Carlito syrichta | 88.93 | 8e-175 | 490 |
| LLPS-Sus-4602 | Sus scrofa | 88.93 | 2e-173 | 487 |
| LLPS-Ict-1903 | Ictidomys tridecemlineatus | 88.57 | 1e-174 | 490 |
| LLPS-Otg-1032 | Otolemur garnettii | 88.57 | 7e-175 | 491 |
| LLPS-Mup-3790 | Mustela putorius furo | 88.57 | 2e-172 | 484 |
| LLPS-Caf-1900 | Canis familiaris | 88.21 | 3e-173 | 486 |
| LLPS-Eqc-4232 | Equus caballus | 88.21 | 4e-173 | 486 |
| LLPS-Loa-4073 | Loxodonta africana | 87.94 | 1e-172 | 485 |
| LLPS-Fec-1174 | Felis catus | 87.81 | 1e-171 | 482 |
| LLPS-Urm-3289 | Ursus maritimus | 87.5 | 1e-171 | 482 |
| LLPS-Bot-1823 | Bos taurus | 87.5 | 2e-169 | 477 |
| LLPS-Mea-2085 | Mesocricetus auratus | 87.41 | 7e-167 | 470 |
| LLPS-Myl-4198 | Myotis lucifugus | 86.7 | 1e-114 | 334 |
| LLPS-Cap-1024 | Cavia porcellus | 86.43 | 3e-170 | 479 |
| LLPS-Xet-0091 | Xenopus tropicalis | 86.42 | 2e-152 | 434 |
| LLPS-Aim-0276 | Ailuropoda melanoleuca | 86.07 | 4e-167 | 471 |
| LLPS-Fud-3211 | Fukomys damarensis | 85.36 | 3e-168 | 474 |
| LLPS-Anp-2808 | Anas platyrhynchos | 84.84 | 5e-152 | 432 |
| LLPS-Sah-3090 | Sarcophilus harrisii | 84.47 | 2e-155 | 442 |
| LLPS-Ran-3814 | Rattus norvegicus | 84.29 | 3e-162 | 458 |
| LLPS-Mum-4111 | Mus musculus | 84.29 | 6e-163 | 460 |
| LLPS-Ora-1572 | Ornithorhynchus anatinus | 83.42 | 5e-110 | 327 |
| LLPS-Asm-0858 | Astyanax mexicanus | 83.2 | 1e-150 | 429 |
| LLPS-Dar-1970 | Danio rerio | 82.99 | 2e-148 | 423 |
| LLPS-Orn-2350 | Oreochromis niloticus | 82.79 | 4e-151 | 430 |
| LLPS-Pof-1808 | Poecilia formosa | 82.79 | 3e-151 | 431 |
| LLPS-Ten-1531 | Tetraodon nigroviridis | 82.3 | 3e-148 | 423 |
| LLPS-Tar-3141 | Takifugu rubripes | 82.3 | 6e-149 | 425 |
| LLPS-Mod-0969 | Monodelphis domestica | 82.17 | 3e-159 | 451 |
| LLPS-Dio-1852 | Dipodomys ordii | 82.08 | 1e-157 | 447 |
| LLPS-Xim-0518 | Xiphophorus maculatus | 81.97 | 2e-149 | 426 |
| LLPS-Scf-0122 | Scleropages formosus | 81.89 | 4e-148 | 423 |
| LLPS-Scm-0542 | Scophthalmus maximus | 81.4 | 5e-146 | 418 |
| LLPS-Orl-1451 | Oryzias latipes | 81.4 | 2e-146 | 419 |
| LLPS-Pes-1955 | Pelodiscus sinensis | 80.66 | 1e-144 | 414 |
| LLPS-Gaga-1046 | Gallus gallus | 78.47 | 4e-153 | 436 |
| LLPS-Meg-0423 | Meleagris gallopavo | 78.47 | 2e-153 | 437 |
| LLPS-Anc-3959 | Anolis carolinensis | 78.16 | 1e-95 | 287 |
| LLPS-Lac-2928 | Latimeria chalumnae | 77.74 | 1e-152 | 434 |
| LLPS-Cea-3004 | Cercocebus atys | 77.14 | 4e-137 | 394 |
| LLPS-Icp-2911 | Ictalurus punctatus | 76.09 | 2e-150 | 429 |
| LLPS-Ova-1380 | Ovis aries | 75.0 | 9e-139 | 399 |
| LLPS-Gaa-0709 | Gasterosteus aculeatus | 74.29 | 1e-149 | 426 |
| LLPS-Tag-3068 | Taeniopygia guttata | 74.17 | 1e-120 | 351 |
| LLPS-Asni-0946 | Aspergillus niger | 73.53 | 4e-52 | 172 |
| LLPS-Tum-0002 | Tuber melanosporum | 69.3 | 1e-108 | 322 |
| LLPS-Fia-2597 | Ficedula albicollis | 69.18 | 1e-128 | 373 |
| LLPS-Leo-0826 | Lepisosteus oculatus | 69.14 | 1e-113 | 334 |
| LLPS-Abg-1934 | Absidia glauca | 68.09 | 1e-111 | 328 |
| LLPS-Asg-0373 | Ashbya gossypii | 67.95 | 3e-111 | 328 |
| LLPS-Usm-0325 | Ustilago maydis | 67.78 | 4e-114 | 337 |
| LLPS-Sac-1110 | Saccharomyces cerevisiae | 67.66 | 3e-112 | 331 |
| LLPS-Yal-0430 | Yarrowia lipolytica | 67.23 | 2e-109 | 324 |
| LLPS-Kop-1486 | Komagataella pastoris | 66.81 | 8e-111 | 327 |
| LLPS-Cii-1324 | Ciona intestinalis | 66.8 | 7e-119 | 349 |
| LLPS-Viv-1033 | Vitis vinifera | 66.67 | 2e-15 | 79.3 |
| LLPS-Gag-0758 | Gaeumannomyces graminis | 66.67 | 2e-111 | 330 |
| LLPS-Spr-1375 | Sporisorium reilianum | 66.53 | 7e-112 | 331 |
| LLPS-Cis-1319 | Ciona savignyi | 66.12 | 1e-116 | 343 |
| LLPS-Orp-1983 | Oryza punctata | 66.04 | 1e-15 | 79.7 |
| LLPS-Trr-1473 | Trichoderma reesei | 65.96 | 7e-111 | 328 |
| LLPS-Put-0877 | Puccinia triticina | 65.67 | 1e-110 | 328 |
| LLPS-Scs-0505 | Sclerotinia sclerotiorum | 65.67 | 3e-107 | 320 |
| LLPS-Trv-0433 | Trichoderma virens | 65.53 | 2e-111 | 329 |
| LLPS-Mel-0173 | Melampsora laricipopulina | 65.38 | 7e-111 | 328 |
| LLPS-Blg-1266 | Blumeria graminis | 65.11 | 3e-107 | 318 |
| LLPS-Fuo-1290 | Fusarium oxysporum | 64.81 | 3e-108 | 321 |
| LLPS-Fuv-0690 | Fusarium verticillioides | 64.81 | 5e-108 | 321 |
| LLPS-Cog-1046 | Colletotrichum gloeosporioides | 64.68 | 6e-108 | 320 |
| LLPS-Drm-2063 | Drosophila melanogaster | 64.64 | 1e-126 | 369 |
| LLPS-Asfu-0708 | Aspergillus fumigatus | 64.56 | 4e-109 | 324 |
| LLPS-Ved-0366 | Verticillium dahliae | 64.53 | 1e-106 | 317 |
| LLPS-Dos-0506 | Dothistroma septosporum | 64.53 | 8e-105 | 313 |
| LLPS-Mao-1450 | Magnaporthe oryzae | 64.53 | 3e-107 | 319 |
| LLPS-Asc-0234 | Aspergillus clavatus | 64.14 | 3e-109 | 325 |
| LLPS-Scp-0546 | Schizosaccharomyces pombe | 63.95 | 4e-102 | 306 |
| LLPS-Amt-1117 | Amborella trichopoda | 63.86 | 2e-87 | 265 |
| LLPS-Cogr-0881 | Colletotrichum graminicola | 63.83 | 6e-107 | 318 |
| LLPS-Beb-1227 | Beauveria bassiana | 63.83 | 1e-107 | 320 |
| LLPS-Nec-1162 | Neurospora crassa | 63.83 | 6e-105 | 313 |
| LLPS-Coo-0213 | Colletotrichum orbiculare | 63.83 | 2e-107 | 319 |
| LLPS-Php-0752 | Physcomitrella patens | 63.79 | 4e-104 | 311 |
| LLPS-Nef-0315 | Neosartorya fischeri | 63.71 | 4e-108 | 322 |
| LLPS-Ast-1189 | Aspergillus terreus | 63.71 | 9e-108 | 320 |
| LLPS-Crn-0670 | Cryptococcus neoformans | 63.64 | 3e-81 | 253 |
| LLPS-Scj-1177 | Schizosaccharomyces japonicus | 63.52 | 3e-102 | 306 |
| LLPS-Asf-0585 | Aspergillus flavus | 63.29 | 4e-108 | 321 |
| LLPS-Aso-1105 | Aspergillus oryzae | 63.29 | 4e-108 | 321 |
| LLPS-Scc-1641 | Schizosaccharomyces cryophilus | 63.25 | 1e-99 | 299 |
| LLPS-Osl-1325 | Ostreococcus lucimarinus | 63.09 | 2e-106 | 315 |
| LLPS-Miv-1570 | Microbotryum violaceum | 62.98 | 1e-106 | 317 |
| LLPS-Zyt-0254 | Zymoseptoria tritici | 62.82 | 2e-103 | 310 |
| LLPS-Zem-1144 | Zea mays | 62.5 | 5e-15 | 77.8 |
| LLPS-Orr-1243 | Oryza rufipogon | 62.5 | 5e-15 | 77.8 |
| LLPS-Lep-2144 | Leersia perrieri | 62.5 | 5e-15 | 78.2 |
| LLPS-Orni-1681 | Oryza nivara | 62.5 | 5e-15 | 77.8 |
| LLPS-Ori-2072 | Oryza indica | 62.5 | 5e-15 | 77.8 |
| LLPS-Pot-0673 | Populus trichocarpa | 62.34 | 4e-101 | 303 |
| LLPS-Asn-0847 | Aspergillus nidulans | 62.03 | 8e-106 | 315 |
| LLPS-Mae-1736 | Manihot esculenta | 62.01 | 1e-100 | 302 |
| LLPS-Phn-1012 | Phaeosphaeria nodorum | 61.97 | 5e-103 | 309 |
| LLPS-Pytr-0573 | Pyrenophora triticirepentis | 61.54 | 6e-102 | 306 |
| LLPS-Lem-1386 | Leptosphaeria maculans | 61.54 | 6e-102 | 306 |
| LLPS-Pyt-0215 | Pyrenophora teres | 61.54 | 1e-101 | 305 |
| LLPS-Nia-2110 | Nicotiana attenuata | 61.47 | 2e-101 | 304 |
| LLPS-Hea-1858 | Helianthus annuus | 61.37 | 4e-92 | 280 |
| LLPS-Cus-0121 | Cucumis sativus | 61.3 | 1e-99 | 299 |
| LLPS-Chr-0935 | Chlamydomonas reinhardtii | 61.28 | 1e-99 | 300 |
| LLPS-Cae-1541 | Caenorhabditis elegans | 61.16 | 3e-108 | 322 |
| LLPS-Dac-1628 | Daucus carota | 61.11 | 8e-101 | 302 |
| LLPS-Bro-0081 | Brassica oleracea | 60.87 | 8e-99 | 297 |
| LLPS-Brr-2496 | Brassica rapa | 60.87 | 4e-99 | 298 |
| LLPS-Arl-2903 | Arabidopsis lyrata | 60.87 | 1e-98 | 296 |
| LLPS-Brn-2333 | Brassica napus | 60.87 | 8e-99 | 297 |
| LLPS-Fus-0726 | Fusarium solani | 60.83 | 3e-92 | 280 |
| LLPS-Glm-1190 | Glycine max | 60.78 | 2e-99 | 298 |
| LLPS-Orbr-1288 | Oryza brachyantha | 60.71 | 1e-14 | 77.0 |
| LLPS-Mua-2596 | Musa acuminata | 60.61 | 1e-82 | 253 |
| LLPS-Gor-0644 | Gossypium raimondii | 60.43 | 9e-101 | 302 |
| LLPS-Art-1149 | Arabidopsis thaliana | 60.43 | 2e-98 | 296 |
| LLPS-Met-0429 | Medicago truncatula | 60.43 | 9e-99 | 297 |
| LLPS-Thc-1512 | Theobroma cacao | 60.43 | 4e-99 | 298 |
| LLPS-Sol-1052 | Solanum lycopersicum | 60.32 | 1e-77 | 241 |
| LLPS-Map-0289 | Magnaporthe poae | 60.08 | 5e-108 | 321 |
| LLPS-Vir-0991 | Vigna radiata | 60.0 | 6e-98 | 295 |
| LLPS-Hov-1762 | Hordeum vulgare | 59.55 | 2e-71 | 229 |
| LLPS-Via-0154 | Vigna angularis | 59.09 | 1e-68 | 218 |
| LLPS-Prp-0716 | Prunus persica | 59.05 | 4e-96 | 291 |
| LLPS-Cym-1036 | Cyanidioschyzon merolae | 58.75 | 7e-95 | 287 |
| LLPS-Brd-1831 | Brachypodium distachyon | 58.43 | 2e-69 | 224 |
| LLPS-Tra-2543 | Triticum aestivum | 58.19 | 2e-90 | 277 |
| LLPS-Sei-1063 | Setaria italica | 57.87 | 2e-69 | 226 |
| LLPS-Coc-0173 | Corchorus capsularis | 57.64 | 2e-88 | 271 |
| LLPS-Sem-1252 | Selaginella moellendorffii | 57.39 | 2e-94 | 285 |
| LLPS-Sot-1698 | Solanum tuberosum | 57.14 | 3e-101 | 303 |
| LLPS-Gas-0647 | Galdieria sulphuraria | 56.43 | 3e-91 | 278 |
| LLPS-Orm-0821 | Oryza meridionalis | 53.65 | 2e-83 | 272 |
| LLPS-Org-1735 | Oryza glaberrima | 53.45 | 7e-86 | 265 |
| LLPS-Ors-1982 | Oryza sativa | 53.45 | 6e-86 | 266 |
| LLPS-Orb-0936 | Oryza barthii | 53.45 | 3e-85 | 270 |
| LLPS-Orgl-1442 | Oryza glumaepatula | 53.02 | 1e-84 | 270 |
| LLPS-Sob-0754 | Sorghum bicolor | 50.83 | 8e-84 | 260 |
| LLPS-Tru-1435 | Triticum urartu | 45.69 | 3e-62 | 203 |
| LLPS-Chc-0950 | Chondrus crispus | 39.13 | 2e-15 | 76.6 |