• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Kop-1486
PAS_chr3_1111

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
Gene Name: PAS_chr3_1111
Ensembl Gene: PAS_chr3_1111
Ensembl Protein: CAY71178
Organism: Komagataella pastoris
Taxa ID: 644223
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, OthersPredicted from orthologs(View)

▼ FUNCTION

Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblCAY71178CAY71178
UniProtC4R6J2, C4R6J2_KOMPG
GeneBankFN392321CAY71178.1
RefSeqXM_002493312.1XP_002493357.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MLTHTVLRAG  TKRTCSTLSV  VRGLATVSQN  QPRLKSFKVY  RWSPDTPEIK  PHMQEYKIDL  60
61    NECGPMVLDA  LLKIKNEQDA  TLTFRRSCRE  GICGSCAMNI  GGRNTLACLC  KIDQNESTEL  120
121   KIYPLPHMFV  VRDLVPDLTH  FYKQYKSIQP  FLQRDSVPSD  GKENLQSIED  RKKLDGLYEC  180
181   ILCACCSTSC  PSYWWNQQEY  LGPAVLMQAY  RWLIDSRDQA  SVARKEMLQN  SMSLYRCHTI  240
241   MNCARTCPKG  LNPGKAIAEI  KKQLAFD  267
Nucleotide CDS Sequence (FASTA)
1     ATGCTTACTC  ACACAGTATT  GAGAGCTGGA  ACTAAGAGAA  CCTGCTCTAC  CCTTTCTGTC  60
61    GTCAGAGGGT  TGGCCACGGT  CTCGCAGAAT  CAACCCAGGC  TGAAGTCATT  CAAAGTGTAT  120
121   CGTTGGTCTC  CTGATACGCC  GGAAATTAAG  CCACATATGC  AAGAATACAA  GATTGATCTG  180
181   AACGAATGTG  GTCCCATGGT  TTTGGATGCT  TTGCTCAAGA  TCAAGAACGA  ACAGGATGCT  240
241   ACACTTACCT  TCCGTAGATC  GTGTCGTGAG  GGTATTTGTG  GATCATGTGC  TATGAACATT  300
301   GGTGGTAGAA  ACACTTTGGC  ATGTTTATGC  AAGATCGACC  AGAATGAGAG  CACGGAACTC  360
361   AAAATTTATC  CTCTTCCTCA  CATGTTTGTA  GTCCGAGACC  TAGTGCCTGA  TTTAACACAC  420
421   TTTTACAAGC  AATACAAATC  GATCCAACCA  TTTTTACAAA  GAGATTCGGT  GCCTAGCGAT  480
481   GGCAAAGAAA  ATTTACAATC  TATTGAGGAT  CGTAAGAAGT  TGGATGGATT  GTACGAGTGT  540
541   ATCTTGTGTG  CCTGCTGTTC  TACGTCTTGC  CCGTCTTATT  GGTGGAATCA  ACAGGAATAT  600
601   TTAGGCCCCG  CGGTTTTAAT  GCAAGCCTAT  AGATGGTTGA  TCGATTCCCG  TGATCAAGCT  660
661   TCTGTGGCAA  GAAAAGAAAT  GTTGCAGAAT  TCAATGTCAC  TATACCGCTG  TCACACAATC  720
721   ATGAACTGTG  CTCGTACTTG  TCCGAAAGGC  TTGAATCCAG  GTAAAGCCAT  TGCGGAAATC  780
781   AAAAAACAGC  TTGCCTTTGA  CTAA  804

▼ KEYWORD

ID
Family
2Fe-2S
3Fe-4S
4Fe-4S
Complete proteome
Iron
Iron-sulfur
Membrane
Metal-binding
Mitochondrion
Mitochondrion inner membrane
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Mitochondrial inner membrane
Molecular Function
2 iron, 2 sulfur cluster binding
Molecular Function
3 iron, 4 sulfur cluster binding
Molecular Function
4 iron, 4 sulfur cluster binding
Molecular Function
Electron transfer activity
Molecular Function
Metal ion binding
Molecular Function
Succinate dehydrogenase (ubiquinone) activity
Biological Process
Tricarboxylic acid cycle

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Sac-1110Saccharomyces cerevisiae85.112e-154 439
LLPS-Asg-0373Ashbya gossypii76.814e-154 437
LLPS-Abg-1934Absidia glauca75.958e-138 395
LLPS-Gag-0758Gaeumannomyces graminis75.211e-136 394
LLPS-Yal-0430Yarrowia lipolytica75.092e-151 431
LLPS-Pof-1808Poecilia formosa75.01e-131 381
LLPS-Xim-0518Xiphophorus maculatus75.02e-131 381
LLPS-Trr-1473Trichoderma reesei74.33e-143 410
LLPS-Scm-0542Scophthalmus maximus73.939e-128 371
LLPS-Ten-1531Tetraodon nigroviridis73.933e-128 373
LLPS-Tar-3141Takifugu rubripes73.936e-129 374
LLPS-Asni-0946Aspergillus niger73.873e-57 185
LLPS-Trv-0433Trichoderma virens73.798e-142 407
LLPS-Xet-0091Xenopus tropicalis73.52e-126 368
LLPS-Asfu-0708Aspergillus fumigatus73.55e-132 383
LLPS-Scf-0122Scleropages formosus73.397e-127 369
LLPS-Usm-0325Ustilago maydis73.281e-128 374
LLPS-Nef-0315Neosartorya fischeri73.086e-131 380
LLPS-Dar-1970Danio rerio73.081e-126 369
LLPS-Anc-3959Anolis carolinensis72.992e-89 271
LLPS-Put-0877Puccinia triticina72.734e-128 373
LLPS-Zyt-0254Zymoseptoria tritici72.652e-133 386
LLPS-Scs-0505Sclerotinia sclerotiorum72.535e-129 375
LLPS-Spr-1375Sporisorium reilianum72.418e-127 369
LLPS-Scc-1641Schizosaccharomyces cryophilus72.342e-127 370
LLPS-Lac-2928Latimeria chalumnae72.082e-127 371
LLPS-Mao-1450Magnaporthe oryzae71.959e-138 396
LLPS-Asc-0234Aspergillus clavatus71.916e-130 377
LLPS-Cogr-0881Colletotrichum graminicola71.63e-137 395
LLPS-Sah-3090Sarcophilus harrisii71.62e-130 378
LLPS-Cea-1029Cercocebus atys71.593e-89 271
LLPS-Asf-0585Aspergillus flavus71.377e-129 374
LLPS-Aso-1105Aspergillus oryzae71.377e-129 374
LLPS-Blg-1266Blumeria graminis71.312e-136 393
LLPS-Coo-0213Colletotrichum orbiculare71.28e-137 394
LLPS-Mod-0969Monodelphis domestica71.024e-128 372
LLPS-Drm-2063Drosophila melanogaster71.012e-128 374
LLPS-Myl-4198Myotis lucifugus70.952e-90 273
LLPS-Fuv-0690Fusarium verticillioides70.923e-137 395
LLPS-Ora-1572Ornithorhynchus anatinus70.812e-88 272
LLPS-Map-0289Magnaporthe poae70.755e-135 390
LLPS-Orl-1451Oryzias latipes70.72e-127 370
LLPS-Fec-1174Felis catus70.689e-130 376
LLPS-Caf-1900Canis familiaris70.683e-130 377
LLPS-Mup-3790Mustela putorius furo70.682e-129 375
LLPS-Bot-1823Bos taurus70.684e-129 375
LLPS-Meg-0423Meleagris gallopavo70.566e-129 375
LLPS-Gaga-1046Gallus gallus70.561e-129 376
LLPS-Fuo-1290Fusarium oxysporum70.521e-136 394
LLPS-Aim-0276Ailuropoda melanoleuca70.283e-130 377
LLPS-Ved-0366Verticillium dahliae70.122e-132 383
LLPS-Amt-1117Amborella trichopoda70.052e-99 296
LLPS-Anp-2808Anas platyrhynchos69.882e-128 373
LLPS-Urm-3289Ursus maritimus69.887e-129 374
LLPS-Mam-1433Macaca mulatta69.881e-128 373
LLPS-Eqc-4232Equus caballus69.885e-129 374
LLPS-Caj-4489Callithrix jacchus69.882e-128 373
LLPS-Aon-4672Aotus nancymaae69.882e-128 373
LLPS-Maf-3260Macaca fascicularis69.881e-128 373
LLPS-Chs-3312Chlorocebus sabaeus69.882e-128 373
LLPS-Mal-1444Mandrillus leucophaeus69.882e-128 373
LLPS-Fud-3211Fukomys damarensis69.722e-128 373
LLPS-Otg-1032Otolemur garnettii69.61e-128 374
LLPS-Orn-2350Oreochromis niloticus69.533e-130 377
LLPS-Pap-0528Pan paniscus69.482e-129 375
LLPS-Pat-3270Pan troglodytes69.482e-129 375
LLPS-Hos-0318Homo sapiens69.482e-129 375
LLPS-Ict-1903Ictidomys tridecemlineatus69.481e-128 374
LLPS-Cas-0522Carlito syrichta69.489e-128 371
LLPS-Poa-1078Pongo abelii69.484e-129 375
LLPS-Cap-1024Cavia porcellus69.482e-128 373
LLPS-Gog-0719Gorilla gorilla69.482e-129 375
LLPS-Sus-4602Sus scrofa69.481e-127 371
LLPS-Paa-1141Papio anubis69.483e-128 372
LLPS-Mel-0173Melampsora laricipopulina69.424e-128 373
LLPS-Mum-4111Mus musculus69.396e-126 367
LLPS-Ran-3814Rattus norvegicus69.397e-126 367
LLPS-Scj-1177Schizosaccharomyces japonicus69.265e-132 382
LLPS-Pes-1955Pelodiscus sinensis69.233e-119 350
LLPS-Mea-2085Mesocricetus auratus69.087e-127 369
LLPS-Loa-4073Loxodonta africana68.775e-129 375
LLPS-Pytr-0573Pyrenophora triticirepentis68.77e-130 377
LLPS-Asm-0858Astyanax mexicanus68.74e-130 377
LLPS-Pyt-0215Pyrenophora teres68.71e-129 377
LLPS-Dio-1852Dipodomys ordii68.577e-127 369
LLPS-Hov-1762Hordeum vulgare68.541e-87 271
LLPS-Brd-1831Brachypodium distachyon68.542e-87 271
LLPS-Phn-1012Phaeosphaeria nodorum68.421e-129 377
LLPS-Crn-0670Cryptococcus neoformans68.422e-104 312
LLPS-Gaa-0709Gasterosteus aculeatus68.369e-129 374
LLPS-Sei-1063Setaria italica68.161e-84 266
LLPS-Orbr-1288Oryza brachyantha67.982e-81 257
LLPS-Zem-1144Zea mays67.986e-85 266
LLPS-Orr-1243Oryza rufipogon67.983e-82 259
LLPS-Orni-1681Oryza nivara67.983e-82 259
LLPS-Ori-2072Oryza indica67.983e-82 259
LLPS-Lep-2144Leersia perrieri67.988e-85 266
LLPS-Nol-2522Nomascus leucogenys67.971e-129 376
LLPS-Lem-1386Leptosphaeria maculans67.897e-129 375
LLPS-Bro-2200Brassica oleracea67.833e-112 332
LLPS-Orp-1983Oryza punctata67.789e-83 261
LLPS-Mae-1736Manihot esculenta67.393e-111 329
LLPS-Scp-0546Schizosaccharomyces pombe67.295e-131 379
LLPS-Beb-1227Beauveria bassiana67.167e-139 399
LLPS-Cog-1046Colletotrichum gloeosporioides67.042e-135 390
LLPS-Art-1149Arabidopsis thaliana66.813e-110 327
LLPS-Nec-1162Neurospora crassa66.549e-136 392
LLPS-Brr-2496Brassica rapa66.527e-111 328
LLPS-Thc-1512Theobroma cacao66.523e-111 329
LLPS-Brn-2187Brassica napus66.527e-111 328
LLPS-Ast-1189Aspergillus terreus66.428e-132 381
LLPS-Hea-1858Helianthus annuus66.383e-105 314
LLPS-Tag-3068Taeniopygia guttata66.373e-105 313
LLPS-Dos-0506Dothistroma septosporum66.33e-136 393
LLPS-Viv-1033Vitis vinifera65.956e-81 256
LLPS-Mua-2596Musa acuminata65.668e-89 269
LLPS-Icp-2911Ictalurus punctatus65.541e-130 379
LLPS-Arl-2903Arabidopsis lyrata65.524e-108 321
LLPS-Pot-0673Populus trichocarpa65.381e-109 325
LLPS-Asn-0847Aspergillus nidulans65.32e-130 378
LLPS-Man-4032Macaca nemestrina65.064e-113 333
LLPS-Rhb-4064Rhinopithecus bieti64.664e-113 333
LLPS-Ova-1380Ovis aries64.542e-114 337
LLPS-Miv-1570Microbotryum violaceum64.447e-127 369
LLPS-Sol-1052Solanum lycopersicum64.46e-87 265
LLPS-Cis-1319Ciona savignyi64.375e-121 354
LLPS-Cii-1324Ciona intestinalis64.341e-125 366
LLPS-Cym-1036Cyanidioschyzon merolae64.322e-105 314
LLPS-Chr-0935Chlamydomonas reinhardtii64.14e-110 327
LLPS-Nia-2110Nicotiana attenuata64.081e-112 332
LLPS-Osl-1325Ostreococcus lucimarinus63.955e-111 328
LLPS-Php-0752Physcomitrella patens63.292e-111 330
LLPS-Cae-1541Caenorhabditis elegans63.071e-115 341
LLPS-Gor-0644Gossypium raimondii62.55e-113 334
LLPS-Dac-1492Daucus carota62.451e-108 322
LLPS-Fia-2597Ficedula albicollis62.162e-113 335
LLPS-Prp-0716Prunus persica61.813e-110 327
LLPS-Sot-1698Solanum tuberosum60.827e-114 336
LLPS-Tum-0002Tuber melanosporum60.376e-116 340
LLPS-Leo-0826Lepisosteus oculatus60.261e-93 283
LLPS-Cus-0121Cucumis sativus60.222e-111 330
LLPS-Met-0429Medicago truncatula60.152e-110 327
LLPS-Glm-1616Glycine max59.573e-97 292
LLPS-Fus-0726Fusarium solani59.486e-116 340
LLPS-Sem-1252Selaginella moellendorffii59.396e-99 296
LLPS-Coc-0173Corchorus capsularis59.234e-95 289
LLPS-Orm-0821Oryza meridionalis58.872e-93 298
LLPS-Via-0154Vigna angularis58.747e-84 257
LLPS-Ors-1982Oryza sativa58.71e-95 291
LLPS-Org-1735Oryza glaberrima58.71e-95 290
LLPS-Orb-0936Oryza barthii58.73e-94 294
LLPS-Vir-0991Vigna radiata58.555e-109 323
LLPS-Tra-2543Triticum aestivum58.526e-96 291
LLPS-Orgl-1442Oryza glumaepatula58.262e-93 293
LLPS-Chc-0950Chondrus crispus58.112e-2297.8
LLPS-Gas-0647Galdieria sulphuraria57.61e-99 300
LLPS-Sob-0754Sorghum bicolor56.33e-92 282
LLPS-Tru-1435Triticum urartu45.935e-69 221