• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Trv-1387
NBP35

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Cytosolic Fe-S cluster assembly factor NBP35; Nucleotide-binding protein 35
Gene Name: NBP35, TRIVIDRAFT_91515
Ensembl Gene: TRIVIDRAFT_91515
Ensembl Protein: EHK22202
Organism: Trichoderma virens
Taxa ID: 413071
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblEHK22202EHK22202
UniProtG9MSP1, G9MSP1_HYPVG
GeneBankABDF02000006EHK22202.1
RefSeqXM_014100954.1XP_013956429.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAPSLEEPEA  IADVLANPLK  QKPQLVAPEP  EHCPGPESER  AGTASSCDGC  PNQAICASAP  60
61    KGPDPDIPII  TARLENVKHK  ILVLSGKGGV  GKSTFTNLLA  HAFSTNPDST  VGVMDADITG  120
121   PSTAKMLGVE  DETIHVSATG  MSPVWVTENL  AVMSIQFMLP  DRDAAIIWRG  PKKNGLIKQF  180
181   LKDVEWGELD  FLLVDTPPGT  SDEHLSVNSF  LKESGIDGAV  VVTTPQEVAL  LDVRKEIDFC  240
241   RKAGIRILGL  AENMSAFVCP  NCKGESQIFK  ASTGGGRALA  EEMDIPFLGS  VPLDPRIRMA  300
301   CDYGESFFDS  FPDSPACIAF  KQVVRNVGRQ  LGLDEKSVLP  E  341
Nucleotide CDS Sequence (FASTA)
1     ATGGCGCCAT  CATTAGAGGA  GCCCGAGGCC  ATCGCCGACG  TCCTCGCCAA  TCCCCTCAAG  60
61    CAGAAACCGC  AGCTCGTTGC  TCCCGAGCCA  GAACACTGTC  CAGGCCCAGA  ATCCGAGCGT  120
121   GCCGGTACAG  CGTCATCATG  CGATGGCTGC  CCTAACCAGG  CCATCTGCGC  CTCTGCCCCC  180
181   AAGGGCCCTG  ATCCAGACAT  CCCGATCATC  ACAGCGCGGC  TGGAGAACGT  CAAGCACAAG  240
241   ATCCTGGTGC  TGAGCGGAAA  GGGCGGCGTC  GGAAAGAGCA  CCTTCACCAA  TCTTCTCGCC  300
301   CACGCCTTTT  CAACAAACCC  AGACAGCACG  GTGGGCGTCA  TGGATGCGGA  CATTACGGGG  360
361   CCCAGCACGG  CCAAGATGCT  GGGCGTGGAG  GACGAGACGA  TTCACGTCAG  CGCTACGGGG  420
421   ATGTCTCCCG  TGTGGGTGAC  GGAGAACCTG  GCAGTCATGT  CGATACAGTT  TATGTTGCCG  480
481   GATAGAGACG  CTGCGATCAT  CTGGAGGGGC  CCGAAGAAGA  ACGGGCTGAT  TAAGCAGTTT  540
541   CTGAAGGACG  TGGAGTGGGG  AGAGCTGGAT  TTCCTGCTGG  TCGACACACC  GCCGGGCACG  600
601   AGCGACGAGC  ATCTGAGCGT  GAACTCTTTC  CTCAAGGAGA  GCGGAATCGA  CGGCGCCGTG  660
661   GTGGTGACAA  CGCCGCAGGA  GGTTGCGCTG  CTGGACGTGC  GCAAGGAAAT  CGACTTTTGC  720
721   CGCAAGGCTG  GCATCCGGAT  CCTGGGGCTG  GCGGAGAACA  TGAGCGCGTT  CGTGTGCCCC  780
781   AACTGCAAGG  GCGAGAGCCA  GATCTTCAAG  GCCAGCACGG  GTGGCGGCCG  GGCACTGGCG  840
841   GAGGAGATGG  ACATTCCGTT  CTTGGGATCG  GTGCCTCTGG  ACCCGAGGAT  ACGCATGGCA  900
901   TGTGATTATG  GGGAGAGCTT  CTTTGACTCG  TTCCCCGATA  GCCCGGCCTG  CATTGCGTTT  960
961   AAGCAGGTAG  TGAGGAATGT  AGGGCGGCAG  CTGGGTTTGG  ATGAGAAGAG  CGTGCTGCCG  1020
1021  GAGTAG  1026

▼ KEYWORD

ID
Family
4Fe-4S
ATP-binding
Complete proteome
Cytoplasm
Iron
Iron-sulfur
Metal-binding
Nucleotide-binding
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Molecular Function
4 iron, 4 sulfur cluster binding
Molecular Function
ATP binding
Molecular Function
Metal ion binding
Biological Process
Iron-sulfur cluster assembly

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Trr-0975Trichoderma reesei97.950.0 686
LLPS-Fus-0425Fusarium solani84.750.0 605
LLPS-Fuv-0201Fusarium verticillioides84.160.0 602
LLPS-Beb-1394Beauveria bassiana83.280.0 590
LLPS-Ved-1261Verticillium dahliae83.190.0 587
LLPS-Cogr-1573Colletotrichum graminicola81.050.0 578
LLPS-Cog-1130Colletotrichum gloeosporioides81.033e-174 494
LLPS-Nec-0324Neurospora crassa80.70.0 569
LLPS-Gag-0354Gaeumannomyces graminis80.00.0 569
LLPS-Map-1387Magnaporthe poae79.710.0 568
LLPS-Scs-0914Sclerotinia sclerotiorum79.530.0 574
LLPS-Mao-0669Magnaporthe oryzae79.410.0 564
LLPS-Coo-1577Colletotrichum orbiculare77.970.0 552
LLPS-Aso-1163Aspergillus oryzae77.430.0 524
LLPS-Asf-1025Aspergillus flavus77.430.0 524
LLPS-Nef-0574Neosartorya fischeri76.470.0 538
LLPS-Asfu-1385Aspergillus fumigatus76.180.0 538
LLPS-Ast-1372Aspergillus terreus75.680.0 514
LLPS-Asni-0687Aspergillus niger75.660.0 540
LLPS-Blg-0859Blumeria graminis75.380.0 526
LLPS-Phn-0182Phaeosphaeria nodorum75.070.0 527
LLPS-Asn-1167Aspergillus nidulans74.780.0 537
LLPS-Pyt-0079Pyrenophora teres74.710.0 530
LLPS-Asc-0101Aspergillus clavatus74.490.0 525
LLPS-Zyt-0095Zymoseptoria tritici74.270.0 538
LLPS-Pytr-1459Pyrenophora triticirepentis74.120.0 528
LLPS-Dos-0275Dothistroma septosporum73.680.0 536
LLPS-Lem-1206Leptosphaeria maculans72.270.0 525
LLPS-Coc-2274Corchorus capsularis71.437e-1063.9
LLPS-Tum-1150Tuber melanosporum70.218e-169 481
LLPS-Kop-1341Komagataella pastoris68.952e-154 443
LLPS-Scp-1600Schizosaccharomyces pombe68.295e-145 420
LLPS-Abg-1874Absidia glauca67.689e-151 434
LLPS-Asg-1251Ashbya gossypii67.463e-143 423
LLPS-Sac-1402Saccharomyces cerevisiae67.313e-152 439
LLPS-Yal-1392Yarrowia lipolytica66.974e-161 461
LLPS-Crn-1140Cryptococcus neoformans63.731e-143 417
LLPS-Scc-1355Schizosaccharomyces cryophilus63.555e-145 420
LLPS-Scj-0784Schizosaccharomyces japonicus63.483e-139 405
LLPS-Miv-0400Microbotryum violaceum62.914e-132 407
LLPS-Chr-0603Chlamydomonas reinhardtii60.342e-95 296
LLPS-Lac-1771Latimeria chalumnae59.872e-131 385
LLPS-Cii-1928Ciona intestinalis59.534e-126 372
LLPS-Dar-2156Danio rerio59.534e-132 387
LLPS-Cis-0316Ciona savignyi58.864e-123 364
LLPS-Asm-3141Astyanax mexicanus58.537e-124 365
LLPS-Tar-3634Takifugu rubripes58.532e-129 380
LLPS-Xim-0511Xiphophorus maculatus58.193e-128 377
LLPS-Icp-3210Ictalurus punctatus58.052e-124 368
LLPS-Mel-1443Melampsora laricipopulina57.937e-127 374
LLPS-Pof-1801Poecilia formosa57.862e-126 372
LLPS-Leo-0351Lepisosteus oculatus57.532e-128 377
LLPS-Fud-1300Fukomys damarensis57.537e-126 371
LLPS-Orn-2766Oreochromis niloticus57.534e-128 377
LLPS-Scf-3341Scleropages formosus57.528e-126 371
LLPS-Chs-2145Chlorocebus sabaeus57.481e-108 325
LLPS-Gaa-3002Gasterosteus aculeatus57.484e-106 319
LLPS-Anc-3990Anolis carolinensis57.242e-129 380
LLPS-Otg-1566Otolemur garnettii57.25e-100 304
LLPS-Gas-0919Galdieria sulphuraria57.192e-110 331
LLPS-Scm-3681Scophthalmus maximus57.192e-126 372
LLPS-Sus-3206Sus scrofa57.099e-107 320
LLPS-Orc-3706Oryctolagus cuniculus57.09e-127 373
LLPS-Dio-1069Dipodomys ordii56.869e-125 368
LLPS-Ict-3254Ictidomys tridecemlineatus56.868e-126 371
LLPS-Cea-2945Cercocebus atys56.526e-125 369
LLPS-Maf-4644Macaca fascicularis56.527e-125 369
LLPS-Mum-3437Mus musculus56.524e-124 367
LLPS-Mea-2993Mesocricetus auratus56.521e-123 365
LLPS-Gog-3094Gorilla gorilla56.523e-125 369
LLPS-Paa-2643Papio anubis56.527e-125 369
LLPS-Ran-4438Rattus norvegicus56.525e-124 366
LLPS-Man-4282Macaca nemestrina56.527e-125 369
LLPS-Pat-3834Pan troglodytes56.529e-125 368
LLPS-Pap-3316Pan paniscus56.529e-125 368
LLPS-Rhb-3890Rhinopithecus bieti56.527e-125 369
LLPS-Mam-4477Macaca mulatta56.527e-125 369
LLPS-Eqc-0673Equus caballus56.521e-123 365
LLPS-Drm-1901Drosophila melanogaster56.256e-103 312
LLPS-Sah-0680Sarcophilus harrisii56.194e-125 369
LLPS-Bot-3831Bos taurus56.191e-123 365
LLPS-Aim-2710Ailuropoda melanoleuca56.191e-123 365
LLPS-Mup-0401Mustela putorius furo56.194e-118 351
LLPS-Hos-4073Homo sapiens56.198e-124 366
LLPS-Cap-2737Cavia porcellus56.195e-124 366
LLPS-Poa-1942Pongo abelii56.192e-123 365
LLPS-Cas-3471Carlito syrichta56.192e-124 367
LLPS-Chc-0549Chondrus crispus56.133e-120 358
LLPS-Fec-3443Felis catus56.032e-124 367
LLPS-Mua-2134Musa acuminata55.881e-117 350
LLPS-Fia-0241Ficedula albicollis55.882e-110 330
LLPS-Caj-3728Callithrix jacchus55.858e-123 363
LLPS-Ova-4271Ovis aries55.854e-123 364
LLPS-Loa-2659Loxodonta africana55.852e-123 365
LLPS-Urm-2678Ursus maritimus55.852e-123 364
LLPS-Gaga-2777Gallus gallus55.851e-119 355
LLPS-Mod-3068Monodelphis domestica55.743e-125 369
LLPS-Caf-2761Canis familiaris55.71e-123 365
LLPS-Nol-0040Nomascus leucogenys55.524e-123 364
LLPS-Tag-0766Taeniopygia guttata55.412e-122 362
LLPS-Myl-3699Myotis lucifugus55.211e-125 370
LLPS-Pes-3109Pelodiscus sinensis54.938e-125 368
LLPS-Ora-3459Ornithorhynchus anatinus54.53e-73 231
LLPS-Pot-0254Populus trichocarpa54.492e-107 325
LLPS-Hea-0913Helianthus annuus54.467e-111 334
LLPS-Orl-3953Oryzias latipes54.364e-110 332
LLPS-Glm-0263Glycine max53.534e-107 324
LLPS-Viv-1170Vitis vinifera53.536e-107 324
LLPS-Ten-3106Tetraodon nigroviridis53.254e-80 252
LLPS-Met-1995Medicago truncatula53.211e-104 318
LLPS-Org-1135Oryza glaberrima53.032e-114 343
LLPS-Spr-0951Sporisorium reilianum53.022e-128 379
LLPS-Orgl-1969Oryza glumaepatula52.731e-113 341
LLPS-Cae-1374Caenorhabditis elegans52.652e-110 331
LLPS-Aon-1710Aotus nancymaae52.573e-54 185
LLPS-Tra-2418Triticum aestivum52.153e-112 337
LLPS-Orb-1816Oryza barthii52.128e-115 344
LLPS-Orp-0991Oryza punctata52.123e-113 340
LLPS-Orbr-1323Oryza brachyantha52.122e-112 338
LLPS-Fuo-0446Fusarium oxysporum52.122e-74 238
LLPS-Zem-0799Zea mays52.121e-114 343
LLPS-Arl-1811Arabidopsis lyrata52.111e-113 341
LLPS-Hov-1601Hordeum vulgare51.992e-112 338
LLPS-Brd-0852Brachypodium distachyon51.988e-115 344
LLPS-Sei-1799Setaria italica51.986e-113 339
LLPS-Amt-2287Amborella trichopoda51.962e-111 335
LLPS-Nia-2633Nicotiana attenuata51.942e-109 330
LLPS-Tru-1954Triticum urartu51.841e-107 335
LLPS-Ori-1029Oryza indica51.821e-114 343
LLPS-Orni-2349Oryza nivara51.821e-114 343
LLPS-Lep-2012Leersia perrieri51.823e-110 338
LLPS-Sob-2472Sorghum bicolor51.821e-112 340
LLPS-Orr-1706Oryza rufipogon51.823e-113 343
LLPS-Orm-1334Oryza meridionalis51.822e-114 343
LLPS-Osl-0648Ostreococcus lucimarinus51.741e-105 320
LLPS-Brn-2398Brassica napus51.671e-112 338
LLPS-Brr-0525Brassica rapa51.679e-113 338
LLPS-Bro-2227Brassica oleracea51.671e-112 338
LLPS-Mae-1350Manihot esculenta51.664e-107 324
LLPS-Sot-0568Solanum tuberosum51.442e-99 304
LLPS-Php-0575Physcomitrella patens51.363e-116 348
LLPS-Phv-2606Phaseolus vulgaris51.367e-107 323
LLPS-Sol-2052Solanum lycopersicum51.341e-107 325
LLPS-Art-0579Arabidopsis thaliana51.24e-113 340
LLPS-Via-1314Vigna angularis51.064e-106 322
LLPS-Sem-1132Selaginella moellendorffii51.043e-114 342
LLPS-Gor-2127Gossypium raimondii50.884e-112 337
LLPS-Mal-1843Mandrillus leucophaeus50.849e-104 314
LLPS-Tut-0708Tursiops truncatus50.591e-81 256
LLPS-Prp-1641Prunus persica50.457e-111 337
LLPS-Anp-3135Anas platyrhynchos50.05e-82 257
LLPS-Thc-0665Theobroma cacao49.712e-112 340
LLPS-Meg-0807Meleagris gallopavo49.611e-81 256
LLPS-Pug-0226Puccinia graminis49.43e-107 326
LLPS-Ors-2248Oryza sativa49.332e-92 286
LLPS-Dac-2267Daucus carota48.683e-91 283
LLPS-Usm-1480Ustilago maydis48.662e-120 361
LLPS-Vir-2207Vigna radiata48.615e-80 254
LLPS-Cym-0671Cyanidioschyzon merolae48.421e-90 281
LLPS-Xet-1295Xenopus tropicalis48.397e-99 302
LLPS-Cus-1898Cucumis sativus48.052e-92 286
LLPS-Put-0149Puccinia triticina47.597e-87 272