• Disorder
  • Domain
  • PTM
  • Variation
  • Mutation
  • Interaction
  • Disease
  • Drug
  • Physicochemical
  • Function
  • Proteomics
  • Structure
  • Localization
  • Expression
  • Element
  • Methylation

LLPS-Tru-0879

Integrated Annotations

▼ OVERVIEW


Status: Unreviewed
Protein Name: Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase beta chain; SCS-beta
Ensembl Gene: TRIUR3_27945
Ensembl Protein: TRIUR3_27945-P1
Organism: Triticum urartu
Taxa ID: 4572
LLPS Type: Others


▼ PROPERTY



——— Disorder propensity (calculated by IUPred2A)

▼ Classification


Condensates:
CondensateEvidenceOrthologs
Mitochondrial RNA granulePredicted from orthologs(View)

▼ FUNCTION


Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

▼ CROSS REFERENCE


DatabaseNucleotide IDProtein ID
EnsemblTRIUR3_27945-T1TRIUR3_27945-P1
UniProtT1NBP4, T1NBP4_TRIUA

▼ SEQUENCE


Protein Sequence (FASTA)
1     IESMNIHEYQ  GKEILKSFGV  RIQEGIVAET  PEQALDAAKR  LKEEYNSDWV  VVKAQIHAGG  60
61    RGKGGGVKLA  KNHDEVVQRA  TDIIGMQLVT  PQTGPEGKKV  SKVLVAQDVY  YPGESETKEF  120
121   YMSVLLDRAS  GRNMIMYSTE  GGMDIEEVAE  KTPHLIFKEE  IDPKVGLQGF  QARKIAFNLG  180
181   LSGAAHKDMV  KFVAALYKAY  DAIDASMFEI  NPVLKTSDDK  ILAVDAKVNL  DENALYRHAD  240
241   IAALRDLSEE  DPTEVEAGKS  NLNYVKLDGN  VGCMVNGAGL  AMATMDIIKL  AGGEPANFLD  300
301   VGGTANAETV  KAGFNIILQD  PNVKAILINI  FGGIVRCDRV  AQGVIDAYQE  IGNIPVPIIV  360
361   RLQGTNAEEA  KKLIDGSGLK  VYSAIALKEA  AD  392
Nucleotide CDS Sequence (FASTA)
1     ATTGAATCAA  TGAATATTCA  CGAATATCAA  GGAAAAGAAA  TACTTAAAAG  TTTCGGAGTA  60
61    CGCATACAAG  AAGGTATTGT  AGCCGAAACC  CCTGAGCAAG  CCTTAGACGC  TGCAAAGAGA  120
121   TTGAAAGAAG  AGTATAATTC  GGACTGGGTG  GTTGTCAAAG  CCCAAATTCA  TGCTGGTGGC  180
181   CGCGGAAAAG  GTGGTGGTGT  GAAATTGGCT  AAAAACCATG  ATGAGGTCGT  GCAACGTGCT  240
241   ACGGATATCA  TCGGGATGCA  GTTGGTAACT  CCTCAAACAG  GGCCAGAAGG  TAAAAAAGTA  300
301   AGCAAAGTGC  TTGTAGCACA  AGATGTGTAC  TACCCTGGAG  AAAGTGAAAC  TAAAGAGTTC  360
361   TATATGTCCG  TACTTTTGGA  TCGTGCTTCT  GGTCGTAATA  TGATCATGTA  CTCTACCGAA  420
421   GGTGGAATGG  ATATTGAAGA  AGTGGCTGAA  AAAACACCAC  ACCTGATCTT  CAAAGAAGAA  480
481   ATTGATCCTA  AAGTAGGTTT  GCAAGGTTTT  CAAGCTCGCA  AAATTGCTTT  CAATTTAGGC  540
541   TTATCAGGTG  CTGCGCACAA  AGACATGGTT  AAATTCGTAG  CAGCATTGTA  CAAAGCATAT  600
601   GATGCTATCG  ATGCATCTAT  GTTCGAAATC  AATCCGGTTC  TAAAAACATC  TGATGACAAA  660
661   ATATTAGCGG  TAGATGCCAA  GGTAAATTTG  GATGAAAATG  CCCTATACCG  TCACGCTGAC  720
721   ATCGCTGCTT  TGCGCGATCT  TTCGGAAGAA  GATCCAACCG  AAGTAGAGGC  TGGTAAATCA  780
781   AACCTGAACT  ACGTGAAGTT  AGATGGTAAC  GTAGGTTGTA  TGGTAAATGG  TGCTGGTTTG  840
841   GCTATGGCGA  CAATGGACAT  CATTAAATTA  GCAGGTGGTG  AGCCAGCTAA  CTTCTTGGAT  900
901   GTTGGTGGTA  CTGCAAATGC  GGAAACAGTA  AAAGCTGGAT  TCAATATCAT  CCTTCAAGAC  960
961   CCGAATGTAA  AAGCAATCTT  AATCAACATT  TTTGGTGGTA  TCGTTCGTTG  TGACCGTGTT  1020
1021  GCTCAAGGTG  TGATTGATGC  TTACCAAGAA  ATTGGAAATA  TTCCAGTGCC  GATCATCGTT  1080
1081  CGTCTTCAAG  GTACGAATGC  AGAAGAAGCT  AAAAAACTAA  TCGATGGATC  TGGTTTGAAA  1140
1141  GTATACTCTG  CCATCGCATT  GAAAGAAGCA  GCAGAT  1176

▼ KEYWORD


ID
Family
ATP-binding
Complete proteome
Ligase
Magnesium
Metal-binding
Mitochondrion
Nucleotide-binding
Reference proteome
Tricarboxylic acid cycle

▼ GENE ONTOLOGY


ID
Classification
Description
Cellular Component
Mitochondrion
Molecular Function
ATP binding
Molecular Function
Magnesium ion binding
Molecular Function
Succinate-CoA ligase (ADP-forming) activity
Biological Process
Tricarboxylic acid cycle

▼ ORTHOLOGY


DrLLPS IDOrganismIdentityE-valueScore
LLPS-Cog-0826Colletotrichum gloeosporioides50.182e-86 275
LLPS-Asn-0084Aspergillus nidulans46.732e-105 325
LLPS-Zem-1047Zea mays46.013e-90 287
LLPS-Sac-1451Saccharomyces cerevisiae45.862e-105 324
LLPS-Asni-1111Aspergillus niger45.841e-105 325
LLPS-Asfu-0213Aspergillus fumigatus45.733e-106 327
LLPS-Asf-0373Aspergillus flavus45.551e-95 301
LLPS-Brr-3031Brassica rapa45.484e-105 323
LLPS-Blg-0257Blumeria graminis45.489e-101 313
LLPS-Tum-0021Tuber melanosporum45.457e-104 321
LLPS-Yal-0561Yarrowia lipolytica45.344e-106 327
LLPS-Abg-1138Absidia glauca45.322e-108 332
LLPS-Ast-0056Aspergillus terreus45.231e-103 320
LLPS-Nef-0014Neosartorya fischeri45.232e-105 325
LLPS-Cogr-0335Colletotrichum graminicola45.238e-97 303
LLPS-Cae-1164Caenorhabditis elegans45.235e-99 308
LLPS-Ran-1334Rattus norvegicus45.135e-98 305
LLPS-Xet-1415Xenopus tropicalis45.114e-92 288
LLPS-Zyt-1202Zymoseptoria tritici45.111e-105 325
LLPS-Cym-0027Cyanidioschyzon merolae45.072e-99 310
LLPS-Cii-1756Ciona intestinalis45.052e-99 310
LLPS-Bro-1681Brassica oleracea44.976e-104 320
LLPS-Brn-0002Brassica napus44.971e-103 320
LLPS-Asc-0544Aspergillus clavatus44.973e-104 322
LLPS-Usm-0563Ustilago maydis44.952e-101 314
LLPS-Lem-1324Leptosphaeria maculans44.951e-101 315
LLPS-Sol-1002Solanum lycopersicum44.893e-101 313
LLPS-Sot-0874Solanum tuberosum44.891e-100 312
LLPS-Arl-0713Arabidopsis lyrata44.863e-103 318
LLPS-Scp-1401Schizosaccharomyces pombe44.844e-104 321
LLPS-Drm-0386Drosophila melanogaster44.759e-95 299
LLPS-Pes-1317Pelodiscus sinensis44.743e-93 292
LLPS-Trr-0933Trichoderma reesei44.721e-101 315
LLPS-Aon-3163Aotus nancymaae44.722e-92 291
LLPS-Cis-0541Ciona savignyi44.727e-103 318
LLPS-Kop-0056Komagataella pastoris44.728e-102 315
LLPS-Mal-3938Mandrillus leucophaeus44.722e-92 291
LLPS-Paa-4441Papio anubis44.721e-92 291
LLPS-Nec-0832Neurospora crassa44.721e-102 318
LLPS-Urm-1457Ursus maritimus44.562e-100 311
LLPS-Chs-2072Chlorocebus sabaeus44.532e-100 312
LLPS-Pat-0223Pan troglodytes44.51e-92 292
LLPS-Hos-1303Homo sapiens44.51e-92 292
LLPS-Nol-4033Nomascus leucogenys44.51e-92 292
LLPS-Gog-2081Gorilla gorilla44.59e-93 292
LLPS-Mod-3573Monodelphis domestica44.475e-98 309
LLPS-Map-0662Magnaporthe poae44.474e-96 301
LLPS-Pytr-1104Pyrenophora triticirepentis44.449e-104 321
LLPS-Pyt-0414Pyrenophora teres44.449e-104 321
LLPS-Nia-1866Nicotiana attenuata44.394e-98 306
LLPS-Mup-0492Mustela putorius furo44.399e-96 302
LLPS-Art-0725Arabidopsis thaliana44.365e-102 315
LLPS-Caf-2525Canis familiaris44.363e-93 292
LLPS-Dos-0292Dothistroma septosporum44.361e-102 318
LLPS-Osl-0712Ostreococcus lucimarinus44.365e-98 305
LLPS-Chc-0582Chondrus crispus44.368e-98 305
LLPS-Scc-1115Schizosaccharomyces cryophilus44.334e-102 316
LLPS-Fec-2272Felis catus44.38e-100 310
LLPS-Eqc-0466Equus caballus44.39e-100 310
LLPS-Sus-2016Sus scrofa44.37e-100 311
LLPS-Asg-1061Ashbya gossypii44.251e-100 312
LLPS-Dac-0483Daucus carota44.254e-99 308
LLPS-Phv-0767Phaseolus vulgaris44.222e-99 308
LLPS-Trv-0404Trichoderma virens44.225e-100 311
LLPS-Phn-1291Phaeosphaeria nodorum44.221e-101 315
LLPS-Coo-0852Colletotrichum orbiculare44.224e-94 296
LLPS-Amt-1300Amborella trichopoda44.175e-87 275
LLPS-Ora-1945Ornithorhynchus anatinus44.172e-62 209
LLPS-Caj-4169Callithrix jacchus44.172e-91 288
LLPS-Coc-0369Corchorus capsularis44.112e-99 309
LLPS-Scj-0526Schizosaccharomyces japonicus44.086e-104 321
LLPS-Asm-2536Astyanax mexicanus44.074e-98 306
LLPS-Mea-0877Mesocricetus auratus44.069e-79 253
LLPS-Orc-3988Oryctolagus cuniculus44.021e-99 310
LLPS-Mum-3368Mus musculus44.022e-99 309
LLPS-Glm-2497Glycine max43.972e-99 309
LLPS-Fud-0525Fukomys damarensis43.925e-93 291
LLPS-Orn-1384Oreochromis niloticus43.96e-98 304
LLPS-Scf-3637Scleropages formosus43.871e-91 290
LLPS-Fia-2214Ficedula albicollis43.82e-96 300
LLPS-Otg-4308Otolemur garnettii43.82e-99 309
LLPS-Meg-2722Meleagris gallopavo43.772e-97 304
LLPS-Anc-1400Anolis carolinensis43.772e-96 301
LLPS-Gaga-1412Gallus gallus43.772e-97 304
LLPS-Bot-4226Bos taurus43.776e-98 305
LLPS-Myl-2055Myotis lucifugus43.779e-64 212
LLPS-Beb-0661Beauveria bassiana43.729e-101 313
LLPS-Fuo-0481Fusarium oxysporum43.727e-101 313
LLPS-Ved-0064Verticillium dahliae43.726e-93 293
LLPS-Fuv-1001Fusarium verticillioides43.726e-101 313
LLPS-Gag-0432Gaeumannomyces graminis43.721e-97 305
LLPS-Mao-1359Magnaporthe oryzae43.726e-99 308
LLPS-Aim-0250Ailuropoda melanoleuca43.642e-95 300
LLPS-Mam-4070Macaca mulatta43.624e-87 278
LLPS-Gaa-1267Gasterosteus aculeatus43.569e-97 302
LLPS-Loa-3665Loxodonta africana43.544e-96 301
LLPS-Cap-2900Cavia porcellus43.516e-98 305
LLPS-Ova-0560Ovis aries43.513e-97 303
LLPS-Sob-0565Sorghum bicolor43.51e-100 312
LLPS-Fus-1060Fusarium solani43.473e-100 312
LLPS-Hea-2340Helianthus annuus43.471e-97 304
LLPS-Via-0769Vigna angularis43.478e-98 305
LLPS-Sei-1329Setaria italica43.472e-100 311
LLPS-Leo-1344Lepisosteus oculatus43.466e-98 305
LLPS-Spr-0468Sporisorium reilianum43.434e-101 313
LLPS-Mel-1187Melampsora laricipopulina43.433e-91 288
LLPS-Cea-3119Cercocebus atys43.423e-88 280
LLPS-Pap-2675Pan paniscus43.391e-92 291
LLPS-Dio-0117Dipodomys ordii43.392e-94 297
LLPS-Aso-0415Aspergillus oryzae43.371e-97 305
LLPS-Xim-0252Xiphophorus maculatus43.31e-96 302
LLPS-Tar-1659Takifugu rubripes43.31e-94 296
LLPS-Thc-1032Theobroma cacao43.252e-97 303
LLPS-Lac-2314Latimeria chalumnae43.161e-90 285
LLPS-Rhb-4171Rhinopithecus bieti43.145e-96 301
LLPS-Poa-2372Pongo abelii43.142e-95 300
LLPS-Php-0392Physcomitrella patens43.113e-89 283
LLPS-Cas-2235Carlito syrichta43.082e-91 288
LLPS-Pug-0329Puccinia graminis43.049e-92 289
LLPS-Ten-0508Tetraodon nigroviridis43.049e-96 300
LLPS-Mae-2353Manihot esculenta43.09e-97 302
LLPS-Dar-1599Danio rerio42.979e-96 300
LLPS-Pof-3972Poecilia formosa42.934e-94 296
LLPS-Man-1042Macaca nemestrina42.891e-96 303
LLPS-Maf-3242Macaca fascicularis42.899e-97 303
LLPS-Viv-0627Vitis vinifera42.861e-97 304
LLPS-Cus-0361Cucumis sativus42.866e-98 305
LLPS-Tag-3335Taeniopygia guttata42.811e-73 239
LLPS-Sem-0805Selaginella moellendorffii42.784e-91 288
LLPS-Anp-0344Anas platyrhynchos42.771e-72 238
LLPS-Scm-3874Scophthalmus maximus42.753e-95 298
LLPS-Mua-1569Musa acuminata42.712e-98 306
LLPS-Chr-1285Chlamydomonas reinhardtii42.641e-93 294
LLPS-Met-0285Medicago truncatula42.612e-95 298
LLPS-Pot-0936Populus trichocarpa42.52e-95 298
LLPS-Prp-0831Prunus persica42.52e-94 296
LLPS-Ict-0372Ictidomys tridecemlineatus42.395e-94 296
LLPS-Sah-1082Sarcophilus harrisii42.362e-94 297
LLPS-Hov-0503Hordeum vulgare42.366e-95 297
LLPS-Tra-0273Triticum aestivum42.366e-95 297
LLPS-Miv-0055Microbotryum violaceum42.287e-92 289
LLPS-Ors-0677Oryza sativa42.253e-96 300
LLPS-Orm-1033Oryza meridionalis42.253e-96 300
LLPS-Orr-0425Oryza rufipogon42.253e-96 300
LLPS-Org-0003Oryza glaberrima42.253e-96 300
LLPS-Orb-0232Oryza barthii42.253e-96 300
LLPS-Ori-0269Oryza indica42.253e-96 300
LLPS-Orni-0252Oryza nivara42.253e-96 300
LLPS-Lep-1662Leersia perrieri42.258e-96 300
LLPS-Orgl-0621Oryza glumaepatula42.253e-96 300
LLPS-Gor-1977Gossypium raimondii42.112e-93 293
LLPS-Orl-0171Oryzias latipes42.071e-92 293
LLPS-Icp-3874Ictalurus punctatus42.073e-90 288
LLPS-Orbr-0971Oryza brachyantha41.758e-95 297
LLPS-Brd-0292Brachypodium distachyon41.753e-93 293
LLPS-Put-0845Puccinia triticina41.492e-70 231
LLPS-Vir-0194Vigna radiata41.12e-88 280
LLPS-Gas-0957Galdieria sulphuraria40.851e-99 310
LLPS-Crn-1328Cryptococcus neoformans40.611e-94 296