• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Ten-3137
GSTENG00038514001

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Actin-related protein 2/3 complex subunit
Gene Name: GSTENG00038514001
Ensembl Gene: ENSTNIG00000019780.1
Ensembl Protein: ENSTNIP00000023043.1
Organism: Tetraodon nigroviridis
Taxa ID: 99883
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ FUNCTION

Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSTNIT00000023285.1ENSTNIP00000023043.1
UniProtQ4RBH0, Q4RBH0_TETNG
GeneBankCAAE01021483CAG14263.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSLHQFLLEP  ITCHAWNRDR  TQIAISPNNH  EVHIYKKSGN  QWLKTHELKE  HNGHITGIDW  60
61    APKSDRIVTC  GADRNAYVWS  QKDGLWKPTL  VILRINRAAT  FVKWSPLENK  FAVGSGARLI  120
121   SVCYFESEND  WWVSKHIKKP  IRSTILSLDW  HPNNILLAAG  SCDFKCRVFS  AYIKEVEEKP  180
181   GPTPWGSKMP  FGAVLAEFGG  AGGGGWVHSV  SFSASGNRLA  WVSHDSTVTV  VDSSKTTSPS  240
241   QLKTEFLPLL  SVIFVSENSV  VAAGHDCCPM  LFRCDDSGTL  TFVSKLDLPK  QSIQRNISAM  300
301   ERFRNMDKRA  TTEDRNTALD  TLHQNSITQV  SIYEGDKRDC  RKFCTTGIDG  AMTIWDFKSL  360
361   EASIQGLRIM  370
Nucleotide CDS Sequence (FASTA)
1     ATGTCCCTTC  ATCAGTTTCT  GCTGGAACCC  ATCACCTGCC  ACGCGTGGAA  TCGCGATCGG  60
61    ACGCAAATTG  CCATCAGTCC  CAACAACCAT  GAAGTTCATA  TCTACAAGAA  GAGTGGCAAC  120
121   CAGTGGCTAA  AGACCCATGA  GCTGAAAGAG  CACAATGGAC  ACATAACAGG  CATCGACTGG  180
181   GCCCCTAAGA  GTGACCGCAT  AGTGACGTGC  GGAGCAGACC  GTAACGCCTA  CGTATGGTCC  240
241   CAGAAGGACG  GGCTATGGAA  GCCCACTCTG  GTCATCCTCA  GGATCAACCG  AGCTGCCACC  300
301   TTTGTCAAGT  GGTCTCCGCT  GGAGAACAAG  TTTGCGGTCG  GCAGCGGCGC  TCGCCTCATC  360
361   TCTGTCTGCT  ACTTTGAGTC  GGAGAATGAC  TGGTGGGTGA  GCAAGCACAT  CAAGAAGCCG  420
421   ATCCGCTCCA  CCATCCTCAG  CCTGGACTGG  CATCCCAACA  ACATTCTGCT  GGCGGCTGGA  480
481   TCCTGTGACT  TCAAATGCAG  GGTGTTCTCA  GCCTACATTA  AGGAGGTGGA  AGAGAAACCA  540
541   GGTCCCACAC  CCTGGGGCAG  CAAGATGCCA  TTTGGGGCCG  TTCTTGCAGA  GTTTGGAGGA  600
601   GCGGGAGGAG  GGGGTTGGGT  CCACTCCGTC  TCCTTCTCCG  CCTCTGGTAA  CCGCCTGGCC  660
661   TGGGTCAGTC  ACGACAGCAC  TGTTACTGTG  GTGGACAGCT  CGAAGACCAC  CAGTCCTTCA  720
721   CAGCTGAAGA  CGGAGTTTCT  CCCACTCCTC  AGTGTCATTT  TCGTTTCAGA  GAACAGCGTC  780
781   GTAGCTGCAG  GCCATGACTG  TTGCCCCATG  CTGTTCCGTT  GTGACGATAG  CGGAACGCTG  840
841   ACGTTTGTGT  CAAAGCTTGA  CCTCCCCAAG  CAGAGCATCC  AGAGGAACAT  CTCTGCCATG  900
901   GAGCGCTTCA  GGAACATGGA  CAAGCGAGCC  ACCACCGAGG  ACCGCAACAC  TGCACTGGAC  960
961   ACACTGCACC  AGAATAGCAT  CACCCAAGTG  TCTATCTACG  AGGGAGACAA  AAGGGATTGT  1020
1021  CGTAAATTCT  GCACCACAGG  CATCGATGGG  GCAATGACCA  TCTGGGACTT  CAAGAGTCTA  1080
1081  GAAGCCTCCA  TCCAGGGTCT  CCGCATCATG  TGA  1113

▼ KEYWORD

ID
Family
Actin-binding
Complete proteome
Cytoplasm
Cytoskeleton
Reference proteome
WD repeat

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Arp2/3 protein complex
Cellular Component
Cytoplasm
Molecular Function
Actin binding
Biological Process
Arp2/3 complex-mediated actin nucleation

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Tar-2841Takifugu rubripes98.650.0 691
LLPS-Pof-0323Poecilia formosa97.30.0 681
LLPS-Gaa-2111Gasterosteus aculeatus97.30.0 686
LLPS-Xim-0466Xiphophorus maculatus97.30.0 681
LLPS-Orn-2169Oreochromis niloticus97.030.0 685
LLPS-Scm-3051Scophthalmus maximus96.760.0 684
LLPS-Orl-1516Oryzias latipes96.490.0 678
LLPS-Tag-2823Taeniopygia guttata91.620.0 665
LLPS-Fia-3549Ficedula albicollis91.620.0 665
LLPS-Anp-2781Anas platyrhynchos91.620.0 667
LLPS-Asm-0700Astyanax mexicanus91.620.0 664
LLPS-Icp-0802Ictalurus punctatus91.620.0 662
LLPS-Poa-4598Pongo abelii91.43e-144 416
LLPS-Leo-0449Lepisosteus oculatus91.40.0 663
LLPS-Anc-0679Anolis carolinensis91.350.0 664
LLPS-Gaga-0493Gallus gallus91.350.0 663
LLPS-Pes-1033Pelodiscus sinensis91.350.0 666
LLPS-Dar-0164Danio rerio91.350.0 661
LLPS-Meg-1505Meleagris gallopavo91.350.0 663
LLPS-Scf-0768Scleropages formosus91.350.0 664
LLPS-Mod-2375Monodelphis domestica90.540.0 660
LLPS-Sah-2146Sarcophilus harrisii90.190.0 654
LLPS-Ora-0840Ornithorhynchus anatinus90.00.0 659
LLPS-Cas-3647Carlito syrichta89.730.0 654
LLPS-Sus-3844Sus scrofa89.730.0 653
LLPS-Nol-4310Nomascus leucogenys89.460.0 651
LLPS-Caf-3663Canis familiaris89.460.0 652
LLPS-Cap-0184Cavia porcellus89.460.0 651
LLPS-Orc-1451Oryctolagus cuniculus89.460.0 651
LLPS-Man-3292Macaca nemestrina89.460.0 651
LLPS-Urm-2070Ursus maritimus89.460.0 651
LLPS-Pap-2201Pan paniscus89.460.0 651
LLPS-Pat-1273Pan troglodytes89.460.0 651
LLPS-Hos-1778Homo sapiens89.460.0 651
LLPS-Fec-2367Felis catus89.460.0 652
LLPS-Myl-0369Myotis lucifugus89.460.0 654
LLPS-Aim-3882Ailuropoda melanoleuca89.460.0 651
LLPS-Bot-0639Bos taurus89.460.0 648
LLPS-Fud-0452Fukomys damarensis89.460.0 651
LLPS-Caj-2367Callithrix jacchus89.460.0 652
LLPS-Cea-1038Cercocebus atys89.460.0 651
LLPS-Aon-2078Aotus nancymaae89.460.0 652
LLPS-Mum-0552Mus musculus89.460.0 652
LLPS-Maf-0057Macaca fascicularis89.460.0 651
LLPS-Otg-3383Otolemur garnettii89.190.0 650
LLPS-Loa-3501Loxodonta africana89.190.0 651
LLPS-Ova-2711Ovis aries89.190.0 650
LLPS-Tut-1412Tursiops truncatus89.080.0 607
LLPS-Ran-0421Rattus norvegicus88.990.0 567
LLPS-Lac-1030Latimeria chalumnae88.680.0 646
LLPS-Mam-1468Macaca mulatta88.560.0 630
LLPS-Eqc-1644Equus caballus88.540.0 606
LLPS-Ict-2724Ictidomys tridecemlineatus88.520.0 635
LLPS-Dio-3115Dipodomys ordii87.370.0 632
LLPS-Mal-3748Mandrillus leucophaeus86.740.0 608
LLPS-Paa-0239Papio anubis83.560.0 587
LLPS-Xet-2557Xenopus tropicalis81.940.0 589
LLPS-Chs-0908Chlorocebus sabaeus73.190.0 557
LLPS-Gog-2266Gorilla gorilla68.02e-151 438
LLPS-Mea-1286Mesocricetus auratus66.229e-179 509
LLPS-Mup-1341Mustela putorius furo65.683e-178 508
LLPS-Rhb-0043Rhinopithecus bieti64.899e-176 501
LLPS-Drm-1624Drosophila melanogaster55.319e-136 399
LLPS-Cis-0769Ciona savignyi55.02e-129 384
LLPS-Cae-1715Caenorhabditis elegans54.95e-127 377
LLPS-Cii-2329Ciona intestinalis54.324e-132 390
LLPS-Asni-1565Aspergillus niger49.583e-105 321
LLPS-Ast-1398Aspergillus terreus48.891e-106 324
LLPS-Aso-1473Aspergillus oryzae48.061e-100 309
LLPS-Nef-0952Neosartorya fischeri47.784e-104 318
LLPS-Asf-1538Aspergillus flavus47.788e-95 304
LLPS-Sol-0504Solanum lycopersicum47.66e-66 229
LLPS-Brr-3002Brassica rapa47.543e-0857.4
LLPS-Asfu-0290Aspergillus fumigatus47.53e-104 318
LLPS-Asc-0587Aspergillus clavatus47.55e-104 318
LLPS-Amt-2206Amborella trichopoda47.476e-50 176
LLPS-Asn-1331Aspergillus nidulans47.354e-103 315
LLPS-Coo-1452Colletotrichum orbiculare47.223e-100 308
LLPS-Phv-2528Phaseolus vulgaris47.061e-62 207
LLPS-Abg-0834Absidia glauca47.035e-106 323
LLPS-Cog-0983Colletotrichum gloeosporioides46.671e-97 301
LLPS-Fuv-1401Fusarium verticillioides46.521e-96 299
LLPS-Scj-1410Schizosaccharomyces japonicus46.517e-96 297
LLPS-Cogr-1658Colletotrichum graminicola46.392e-97 301
LLPS-Pytr-0976Pyrenophora triticirepentis46.247e-98 302
LLPS-Fuo-0081Fusarium oxysporum46.243e-96 298
LLPS-Ved-0132Verticillium dahliae46.131e-98 304
LLPS-Scs-1040Sclerotinia sclerotiorum45.989e-98 302
LLPS-Fus-0415Fusarium solani45.964e-96 298
LLPS-Trr-0084Trichoderma reesei45.967e-96 297
LLPS-Pyt-1261Pyrenophora teres45.966e-98 302
LLPS-Php-1030Physcomitrella patens45.957e-90 284
LLPS-Trv-0229Trichoderma virens45.832e-95 296
LLPS-Beb-1636Beauveria bassiana45.682e-97 301
LLPS-Dos-1175Dothistroma septosporum45.482e-92 288
LLPS-Miv-0360Microbotryum violaceum45.231e-99 308
LLPS-Tum-1563Tuber melanosporum45.214e-93 289
LLPS-Zyt-0493Zymoseptoria tritici45.211e-93 291
LLPS-Gag-1297Gaeumannomyces graminis45.05e-95 295
LLPS-Scc-0280Schizosaccharomyces cryophilus45.04e-99 306
LLPS-Yal-1389Yarrowia lipolytica44.961e-84 268
LLPS-Lem-0667Leptosphaeria maculans44.755e-96 297
LLPS-Put-1335Puccinia triticina44.427e-102 314
LLPS-Nec-1072Neurospora crassa44.351e-94 294
LLPS-Pug-0005Puccinia graminis44.331e-98 305
LLPS-Phn-1331Phaeosphaeria nodorum44.234e-92 289
LLPS-Mel-0026Melampsora laricipopulina44.238e-97 301
LLPS-Sem-2445Selaginella moellendorffii44.152e-85 270
LLPS-Scp-0433Schizosaccharomyces pombe44.094e-95 296
LLPS-Mao-0724Magnaporthe oryzae44.045e-93 290
LLPS-Crn-1480Cryptococcus neoformans43.926e-105 322
LLPS-Blg-1376Blumeria graminis43.775e-92 287
LLPS-Hea-2431Helianthus annuus43.354e-88 278
LLPS-Met-2364Medicago truncatula43.094e-84 267
LLPS-Via-0017Vigna angularis42.971e-84 268
LLPS-Sob-2167Sorghum bicolor42.664e-88 277
LLPS-Viv-0992Vitis vinifera42.635e-87 275
LLPS-Gor-0445Gossypium raimondii42.514e-86 272
LLPS-Thc-1435Theobroma cacao42.472e-85 271
LLPS-Spr-1200Sporisorium reilianum42.443e-101 313
LLPS-Brn-2199Brassica napus42.43e-88 278
LLPS-Usm-1163Ustilago maydis42.361e-101 314
LLPS-Nia-0531Nicotiana attenuata42.363e-83 265
LLPS-Bro-0777Brassica oleracea42.137e-88 277
LLPS-Glm-1553Glycine max42.012e-83 265
LLPS-Mae-2583Manihot esculenta41.673e-81 260
LLPS-Pot-1876Populus trichocarpa41.677e-86 272
LLPS-Vir-1099Vigna radiata41.672e-83 265
LLPS-Sei-1261Setaria italica41.466e-85 269
LLPS-Brd-0826Brachypodium distachyon41.32e-83 265
LLPS-Coc-0388Corchorus capsularis41.291e-83 266
LLPS-Hov-1473Hordeum vulgare41.293e-77 249
LLPS-Orm-1729Oryza meridionalis41.214e-81 261
LLPS-Orr-1912Oryza rufipogon41.213e-81 261
LLPS-Art-2588Arabidopsis thaliana41.212e-79 255
LLPS-Orgl-1846Oryza glumaepatula41.214e-81 261
LLPS-Orni-0974Oryza nivara41.213e-81 261
LLPS-Orb-0875Oryza barthii41.213e-81 261
LLPS-Ors-0129Oryza sativa41.13e-82 262
LLPS-Ori-0691Oryza indica41.12e-82 262
LLPS-Arl-1539Arabidopsis lyrata41.059e-86 271
LLPS-Tra-1085Triticum aestivum41.031e-82 263
LLPS-Orbr-0347Oryza brachyantha40.823e-84 267
LLPS-Mua-0378Musa acuminata40.764e-83 265
LLPS-Prp-0222Prunus persica40.753e-82 262
LLPS-Lep-0877Leersia perrieri40.661e-81 261
LLPS-Dac-1064Daucus carota40.558e-77 248
LLPS-Cus-1470Cucumis sativus40.272e-80 258
LLPS-Kop-0341Komagataella pastoris40.112e-79 254
LLPS-Zem-1804Zea mays40.11e-85 271
LLPS-Tru-0675Triticum urartu38.675e-71 233
LLPS-Asg-0143Ashbya gossypii38.034e-64 215
LLPS-Sac-1174Saccharomyces cerevisiae35.536e-60 204
LLPS-Chr-1120Chlamydomonas reinhardtii34.459e-32 129
LLPS-Sot-2050Solanum tuberosum32.14e-0755.8
LLPS-Orp-2305Oryza punctata31.413e-41 155
LLPS-Osl-1299Ostreococcus lucimarinus28.576e-0652.4