• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Dos-1175
DOTSEDRAFT_47864

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Actin-related protein 2/3 complex subunit
Gene Name: DOTSEDRAFT_47864
Ensembl Gene: DOTSEDRAFT_47864
Ensembl Protein: EME39288
Organism: Dothistroma septosporum
Taxa ID: 675120
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, OthersPredicted from orthologs(View)

▼ FUNCTION

Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblEME39288EME39288
UniProtM2WK09, M2WK09_DOTSN
GeneBankKB446545EME39288.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAAPQIHHLF  HAPISDHSFS  ANRQTLAVTK  DNNVELYSAQ  GNQFRLQDEL  RGHDKLITGV  60
61    DIAPQSGRIV  TCSQDRNAYV  WEPSDTGGWK  PTLVLLRINR  AATCVRWAPN  EAKFAVGSGA  120
121   RIIAVCYFEE  ENDWWVSKHL  KKPLRSTVTS  VAWHPNSVLL  AAGSTDGHAR  VLSSFVKGTD  180
181   ERPEPSVWGE  RLPFNTVCGE  YLNSTAGWVH  SVAFSPSGDA  LAFTAHDSSI  TVVYPSAPEQ  240
241   PPQAVISIST  QLLPFADLLW  ISESEIVCAG  YDCEVYKFGG  SVSGWQLTGS  LEAGAKAGAG  300
301   VAKEESALNM  FRSMDLKGRS  GGTVDDTKLR  TVHQNSINTV  RPYNGGGTGQ  VSQISTSGVD  360
361   GRVVVWKL  368
Nucleotide CDS Sequence (FASTA)
1     ATGGCCGCTC  CACAGATTCA  CCACCTCTTC  CACGCGCCCA  TCTCCGACCA  CTCCTTCTCC  60
61    GCCAACCGCC  AGACCCTCGC  CGTCACTAAG  GACAACAACG  TCGAGCTCTA  TTCCGCGCAA  120
121   GGCAACCAAT  TTCGCCTGCA  AGATGAGCTC  CGCGGCCACG  ACAAGCTAAT  CACTGGAGTC  180
181   GATATCGCTC  CCCAGTCCGG  TCGCATTGTC  ACATGCTCGC  AAGATCGCAA  TGCTTACGTA  240
241   TGGGAGCCTT  CCGATACTGG  CGGCTGGAAG  CCAACACTCG  TGCTGCTGCG  CATCAACAGA  300
301   GCTGCAACAT  GTGTACGATG  GGCACCGAAT  GAGGCCAAGT  TCGCGGTTGG  TAGCGGTGCT  360
361   CGCATCATTG  CAGTATGCTA  CTTTGAGGAA  GAGAACGATT  GGTGGGTCTC  GAAACACTTG  420
421   AAGAAGCCAT  TGCGATCTAC  CGTCACCTCT  GTGGCATGGC  ATCCGAACAG  CGTTCTTCTT  480
481   GCTGCCGGCA  GCACGGATGG  TCATGCACGA  GTTCTGAGCT  CGTTCGTCAA  AGGTACAGAT  540
541   GAGAGGCCCG  AGCCCAGCGT  TTGGGGAGAG  AGGTTGCCCT  TTAACACCGT  CTGCGGAGAA  600
601   TACTTGAACT  CGACCGCCGG  TTGGGTCCAC  AGCGTTGCGT  TCTCGCCATC  TGGCGATGCT  660
661   TTGGCATTCA  CGGCACACGA  CAGCTCGATC  ACTGTCGTCT  ACCCGTCTGC  TCCGGAACAG  720
721   CCTCCGCAGG  CCGTCATCTC  TATTTCGACT  CAGCTTCTGC  CGTTCGCAGA  TTTGCTATGG  780
781   ATCAGCGAGA  GTGAGATCGT  CTGCGCTGGC  TATGATTGCG  AGGTATACAA  GTTCGGCGGC  840
841   TCCGTGTCAG  GCTGGCAATT  GACTGGCTCC  CTCGAAGCCG  GCGCAAAGGC  CGGAGCTGGT  900
901   GTGGCCAAGG  AGGAGAGCGC  CTTGAATATG  TTCCGCTCGA  TGGACTTGAA  GGGTCGCAGT  960
961   GGCGGCACTG  TTGATGACAC  AAAGCTACGT  ACCGTCCATC  AGAACAGCAT  CAACACTGTC  1020
1021  CGTCCATACA  ACGGCGGCGG  CACCGGCCAG  GTCAGCCAAA  TCAGCACGAG  CGGTGTCGAT  1080
1081  GGACGAGTCG  TGGTGTGGAA  GCTGTAA  1107

▼ KEYWORD

ID
Family
Actin-binding
Complete proteome
Cytoplasm
Cytoskeleton
Reference proteome
WD repeat

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Actin cortical patch
Cellular Component
Arp2/3 protein complex
Molecular Function
Actin binding
Biological Process
Arp2/3 complex-mediated actin nucleation

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Zyt-0493Zymoseptoria tritici85.60.0 651
LLPS-Phn-1331Phaeosphaeria nodorum74.180.0 567
LLPS-Ved-0132Verticillium dahliae73.910.0 563
LLPS-Lem-0667Leptosphaeria maculans73.640.0 566
LLPS-Pytr-0976Pyrenophora triticirepentis73.370.0 563
LLPS-Pyt-1261Pyrenophora teres73.10.0 561
LLPS-Cogr-1658Colletotrichum graminicola72.680.0 559
LLPS-Coo-1452Colletotrichum orbiculare72.680.0 557
LLPS-Trv-0229Trichoderma virens72.40.0 548
LLPS-Beb-1636Beauveria bassiana72.40.0 544
LLPS-Trr-0084Trichoderma reesei72.40.0 550
LLPS-Nec-1072Neurospora crassa72.160.0 552
LLPS-Ast-1398Aspergillus terreus71.980.0 541
LLPS-Fuo-0081Fusarium oxysporum71.580.0 543
LLPS-Fuv-1401Fusarium verticillioides71.580.0 544
LLPS-Mao-0724Magnaporthe oryzae71.470.0 544
LLPS-Fus-0415Fusarium solani71.310.0 543
LLPS-Cog-0983Colletotrichum gloeosporioides71.310.0 536
LLPS-Scs-1040Sclerotinia sclerotiorum71.310.0 545
LLPS-Gag-1297Gaeumannomyces graminis71.120.0 544
LLPS-Asni-1565Aspergillus niger70.920.0 536
LLPS-Nef-0952Neosartorya fischeri70.650.0 545
LLPS-Asfu-0290Aspergillus fumigatus70.380.0 543
LLPS-Asc-0587Aspergillus clavatus70.380.0 543
LLPS-Asn-1331Aspergillus nidulans70.110.0 532
LLPS-Aso-1473Aspergillus oryzae69.020.0 524
LLPS-Asf-1538Aspergillus flavus68.899e-177 515
LLPS-Blg-1376Blumeria graminis68.750.0 528
LLPS-Tum-1563Tuber melanosporum64.933e-164 471
LLPS-Yal-1389Yarrowia lipolytica56.645e-141 413
LLPS-Poa-4598Pongo abelii54.015e-84 262
LLPS-Kop-0341Komagataella pastoris53.134e-130 385
LLPS-Scp-0433Schizosaccharomyces pombe53.04e-133 393
LLPS-Miv-0360Microbotryum violaceum52.247e-126 375
LLPS-Scj-1410Schizosaccharomyces japonicus52.022e-129 384
LLPS-Crn-1480Cryptococcus neoformans51.263e-137 405
LLPS-Abg-0834Absidia glauca51.229e-127 376
LLPS-Scc-0280Schizosaccharomyces cryophilus51.044e-129 382
LLPS-Cas-3882Carlito syrichta49.242e-85 268
LLPS-Pug-0005Puccinia graminis49.237e-122 365
LLPS-Mel-0026Melampsora laricipopulina48.852e-124 372
LLPS-Put-1335Puccinia triticina48.742e-122 367
LLPS-Usm-1163Ustilago maydis48.424e-123 369
LLPS-Spr-1200Sporisorium reilianum48.192e-123 370
LLPS-Ran-0421Rattus norvegicus46.717e-94 290
LLPS-Icp-0802Ictalurus punctatus46.31e-102 314
LLPS-Dar-0164Danio rerio46.071e-102 314
LLPS-Ten-3137Tetraodon nigroviridis46.033e-102 313
LLPS-Scf-0768Scleropages formosus46.037e-101 310
LLPS-Eqc-1644Equus caballus45.81e-91 288
LLPS-Tut-1412Tursiops truncatus45.85e-93 289
LLPS-Scm-3051Scophthalmus maximus45.538e-102 312
LLPS-Leo-0449Lepisosteus oculatus45.366e-101 310
LLPS-Drm-1624Drosophila melanogaster45.32e-102 314
LLPS-Orn-2169Oreochromis niloticus45.266e-101 310
LLPS-Asm-0700Astyanax mexicanus45.262e-100 312
LLPS-Pof-0323Poecilia formosa45.217e-101 310
LLPS-Pes-1033Pelodiscus sinensis45.217e-99 305
LLPS-Xim-0466Xiphophorus maculatus45.217e-101 310
LLPS-Myl-0369Myotis lucifugus45.212e-97 301
LLPS-Aon-2078Aotus nancymaae45.218e-98 302
LLPS-Anp-2781Anas platyrhynchos44.934e-98 303
LLPS-Gaa-2111Gasterosteus aculeatus44.892e-100 310
LLPS-Tar-2841Takifugu rubripes44.728e-101 310
LLPS-Anc-0679Anolis carolinensis44.692e-97 301
LLPS-Otg-3383Otolemur garnettii44.691e-97 302
LLPS-Mam-1468Macaca mulatta44.661e-96 300
LLPS-Cap-0184Cavia porcellus44.662e-97 301
LLPS-Caf-3663Canis familiaris44.665e-97 301
LLPS-Tag-2823Taeniopygia guttata44.667e-99 305
LLPS-Nol-4310Nomascus leucogenys44.662e-97 301
LLPS-Ict-2724Ictidomys tridecemlineatus44.663e-97 300
LLPS-Loa-3501Loxodonta africana44.661e-97 301
LLPS-Man-3292Macaca nemestrina44.662e-97 301
LLPS-Mod-2375Monodelphis domestica44.661e-96 300
LLPS-Fec-2367Felis catus44.664e-97 301
LLPS-Hos-1778Homo sapiens44.662e-97 301
LLPS-Urm-2070Ursus maritimus44.662e-97 301
LLPS-Pap-2201Pan paniscus44.662e-97 301
LLPS-Pat-1273Pan troglodytes44.662e-97 301
LLPS-Orc-1451Oryctolagus cuniculus44.662e-97 301
LLPS-Fia-3549Ficedula albicollis44.667e-99 305
LLPS-Bot-0639Bos taurus44.664e-96 300
LLPS-Ova-2711Ovis aries44.665e-97 301
LLPS-Aim-3882Ailuropoda melanoleuca44.662e-97 301
LLPS-Sus-3844Sus scrofa44.662e-97 301
LLPS-Sah-2146Sarcophilus harrisii44.661e-96 300
LLPS-Cea-1038Cercocebus atys44.662e-97 301
LLPS-Orl-1516Oryzias latipes44.666e-99 305
LLPS-Mum-0552Mus musculus44.668e-98 302
LLPS-Maf-0057Macaca fascicularis44.662e-97 301
LLPS-Caj-2367Callithrix jacchus44.662e-97 301
LLPS-Fud-0452Fukomys damarensis44.662e-97 301
LLPS-Xet-2557Xenopus tropicalis44.541e-95 296
LLPS-Dio-3115Dipodomys ordii44.418e-97 300
LLPS-Gaga-0493Gallus gallus44.388e-98 302
LLPS-Meg-1505Meleagris gallopavo44.388e-98 302
LLPS-Ora-0840Ornithorhynchus anatinus44.387e-97 300
LLPS-Mal-3748Mandrillus leucophaeus44.291e-92 288
LLPS-Lac-1030Latimeria chalumnae44.264e-95 295
LLPS-Cii-2329Ciona intestinalis43.987e-90 281
LLPS-Paa-0239Papio anubis43.561e-91 286
LLPS-Amt-2206Amborella trichopoda43.25e-50 176
LLPS-Cae-1715Caenorhabditis elegans42.938e-93 289
LLPS-Chs-0908Chlorocebus sabaeus42.782e-97 301
LLPS-Asg-0143Ashbya gossypii42.714e-97 300
LLPS-Sac-1174Saccharomyces cerevisiae42.458e-96 297
LLPS-Rhb-0043Rhinopithecus bieti42.086e-97 300
LLPS-Gog-3278Gorilla gorilla42.086e-97 300
LLPS-Mup-1341Mustela putorius furo41.81e-95 296
LLPS-Mea-1286Mesocricetus auratus41.85e-96 298
LLPS-Cis-0769Ciona savignyi41.582e-84 268
LLPS-Sol-0504Solanum lycopersicum41.513e-58 207
LLPS-Phv-2528Phaseolus vulgaris40.462e-57 194
LLPS-Php-1030Physcomitrella patens39.313e-78 254
LLPS-Sob-2167Sorghum bicolor38.937e-76 246
LLPS-Gor-0445Gossypium raimondii38.773e-77 249
LLPS-Glm-1553Glycine max38.772e-76 247
LLPS-Thc-1435Theobroma cacao38.53e-76 247
LLPS-Hea-2431Helianthus annuus38.243e-74 241
LLPS-Bro-1482Brassica oleracea38.221e-76 248
LLPS-Coc-0388Corchorus capsularis37.972e-75 244
LLPS-Via-0017Vigna angularis37.974e-76 246
LLPS-Met-2364Medicago truncatula37.972e-74 242
LLPS-Sem-2445Selaginella moellendorffii37.976e-74 241
LLPS-Prp-0222Prunus persica37.892e-76 247
LLPS-Arl-0923Arabidopsis lyrata37.896e-76 246
LLPS-Sei-1261Setaria italica37.846e-75 243
LLPS-Dac-1064Daucus carota37.72e-74 242
LLPS-Art-2588Arabidopsis thaliana37.634e-68 225
LLPS-Brn-2199Brassica napus37.632e-76 247
LLPS-Brr-0629Brassica rapa37.62e-75 245
LLPS-Cus-1470Cucumis sativus37.64e-75 244
LLPS-Brd-0826Brachypodium distachyon37.534e-72 236
LLPS-Ors-0129Oryza sativa37.473e-73 239
LLPS-Orbr-0347Oryza brachyantha37.477e-73 238
LLPS-Vir-1099Vigna radiata37.473e-76 246
LLPS-Ori-0691Oryza indica37.472e-73 239
LLPS-Mae-2583Manihot esculenta37.433e-75 244
LLPS-Pot-1876Populus trichocarpa37.371e-77 250
LLPS-Mua-0378Musa acuminata37.171e-74 243
LLPS-Tru-0675Triticum urartu37.118e-66 220
LLPS-Orm-1729Oryza meridionalis37.096e-71 234
LLPS-Orr-1912Oryza rufipogon37.093e-71 235
LLPS-Orgl-1846Oryza glumaepatula37.093e-71 235
LLPS-Orb-0875Oryza barthii37.093e-71 235
LLPS-Orni-0974Oryza nivara37.093e-71 235
LLPS-Tra-1085Triticum aestivum37.04e-70 231
LLPS-Nia-0531Nicotiana attenuata36.972e-75 244
LLPS-Zem-1804Zea mays36.866e-72 236
LLPS-Viv-0992Vitis vinifera36.362e-76 247
LLPS-Lep-0877Leersia perrieri36.196e-70 231
LLPS-Hov-1473Hordeum vulgare36.091e-63 214
LLPS-Orp-2305Oryza punctata33.444e-45 166
LLPS-Chr-1120Chlamydomonas reinhardtii30.272e-36 142