LLPS-Cae-1715
arx-3
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Actin-related protein 2/3 complex subunit |
| Gene Name: | arx-3, CELE_Y79H2A.6, Y79H2A.6 |
| Ensembl Gene: | WBGene00000201 |
| Ensembl Protein: | Y79H2A.6 |
| Organism: | Caenorhabditis elegans |
| Taxa ID: | 6239 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus, Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | Y79H2A.6 | Y79H2A.6 |
| UniProt | Q9U1R7, Q9U1R7_CAEEL | |
| GeneBank | BX284603 | CAB54510.1 |
| RefSeq | NM_067169.4 | NP_499570.1 |
| Entrez | 3565442 |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MSSGVPVLHW NFGIGPITCH AWNKDRTQIA VSASSNDIHI FEWRNGDWQS IHTLSEHDLP 60 61 VTGLDWGTKT NRIVSCSQDK NAFVWTFDKN VWKPELVLVR FNRAATYVKW SPLENKFAVG 120 121 SGAKLVSVCY YEKENDWWVS KQIKKPIRST VTCLDWHSNN VLLAVGSCDF KCRVFSAYVK 180 181 EVDEKPSPNP WGQKMPFGQL MSEYSVGGWV HRVAFSPSGC RLAFVSHDSS VSFVDSTVDS 240 241 QKVQNLLTIH LPFTTVEWIT ENSVVTAGHD CSPVLFVVSQ DVLKEVCKLD VPSAAKSSTV 300 301 NSALQLFKNI DRNNAAEKIN VALKTLHQNR ITQILPHSGT VGNVVKFTTC GTDGIVALWD 360 361 LKNHPSLV 368 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGTCGTCCG GCGTTCCCGT TCTCCACTGG AACTTTGGAA TCGGTCCGAT CACTTGTCAC 60 61 GCTTGGAATA AGGATCGCAC TCAAATTGCC GTATCCGCGT CGTCAAATGA TATTCACATT 120 121 TTCGAGTGGC GCAACGGAGA TTGGCAATCA ATCCATACGC TTTCCGAGCA CGACCTTCCT 180 181 GTAACAGGCC TCGACTGGGG TACAAAAACC AACAGAATCG TCTCATGTTC CCAGGATAAG 240 241 AACGCTTTCG TGTGGACATT CGACAAAAAC GTGTGGAAGC CCGAGCTCGT GCTCGTCCGC 300 301 TTTAATCGCG CCGCCACTTA TGTCAAATGG TCTCCGCTGG AGAACAAGTT TGCCGTCGGA 360 361 AGTGGCGCTA AGCTGGTGTC TGTCTGCTAT TATGAGAAGG AAAATGACTG GTGGGTCTCG 420 421 AAACAAATCA AGAAGCCGAT TCGCTCCACC GTCACCTGCC TTGATTGGCA TTCGAACAAT 480 481 GTTCTTCTGG CCGTTGGATC GTGTGATTTC AAGTGTCGTG TATTTTCTGC CTACGTGAAA 540 541 GAGGTCGACG AGAAGCCGTC GCCAAATCCG TGGGGGCAAA AAATGCCGTT CGGACAGTTG 600 601 ATGAGTGAAT ATTCCGTCGG TGGATGGGTT CATCGAGTCG CTTTTTCGCC GTCCGGGTGT 660 661 CGGTTGGCTT TTGTTTCTCA TGATTCATCG GTTTCATTTG TCGATTCGAC AGTTGACAGC 720 721 CAAAAAGTTC AAAACTTGCT GACCATTCAT CTGCCGTTCA CAACAGTCGA ATGGATTACT 780 781 GAGAACAGTG TTGTCACGGC TGGTCACGAC TGCTCGCCGG TGCTCTTTGT AGTGTCTCAA 840 841 GATGTTTTGA AAGAAGTTTG CAAATTGGAT GTCCCATCAG CGGCCAAGTC ATCGACGGTT 900 901 AACAGTGCTC TTCAGCTGTT CAAAAATATC GATCGAAATA ATGCTGCGGA AAAGATTAAC 960 961 GTCGCCTTGA AGACACTCCA TCAAAATCGA ATTACTCAAA TCCTACCTCA CTCTGGAACC 1020 1021 GTCGGAAATG TTGTGAAATT CACAACATGT GGAACTGACG GAATTGTTGC ACTTTGGGAT 1080 1081 TTGAAGAATC ACCCATCACT CGTCTAA 1107 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Arp2/3 protein complex | |
Cellular Component | Cytoplasm | |
Molecular Function | Actin filament binding | |
Biological Process | Arp2/3 complex-mediated actin nucleation |
▼ ANNOTATION
| Disorder | ||||
| IUPred2A | ||||
| Drug | ||||
| CTD | ||||
| Physicochemical | ||||
| Compute pI/Mw | AAindex | |||
| Localization | ||||
| COMPARTMENTS | ||||
| Element | ||||
| circBase | RAID | microRNA.org | ||
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Poa-4598 | Pongo abelii | 66.36 | 1e-104 | 315 |
| LLPS-Ran-0421 | Rattus norvegicus | 59.57 | 5e-129 | 380 |
| LLPS-Mam-1468 | Macaca mulatta | 57.3 | 3e-135 | 399 |
| LLPS-Ova-2711 | Ovis aries | 57.26 | 1e-137 | 405 |
| LLPS-Ict-2724 | Ictidomys tridecemlineatus | 57.22 | 6e-136 | 400 |
| LLPS-Bot-0639 | Bos taurus | 56.91 | 9e-136 | 401 |
| LLPS-Dio-3115 | Dipodomys ordii | 56.82 | 5e-134 | 395 |
| LLPS-Anc-0679 | Anolis carolinensis | 56.79 | 1e-135 | 399 |
| LLPS-Caf-3663 | Canis familiaris | 56.71 | 5e-136 | 401 |
| LLPS-Cap-0184 | Cavia porcellus | 56.71 | 2e-136 | 400 |
| LLPS-Cas-3647 | Carlito syrichta | 56.71 | 2e-136 | 401 |
| LLPS-Nol-4310 | Nomascus leucogenys | 56.71 | 2e-136 | 400 |
| LLPS-Hos-1778 | Homo sapiens | 56.71 | 2e-136 | 400 |
| LLPS-Urm-2070 | Ursus maritimus | 56.71 | 2e-136 | 400 |
| LLPS-Pap-2201 | Pan paniscus | 56.71 | 2e-136 | 400 |
| LLPS-Pat-1273 | Pan troglodytes | 56.71 | 2e-136 | 400 |
| LLPS-Man-3292 | Macaca nemestrina | 56.71 | 2e-136 | 400 |
| LLPS-Loa-3501 | Loxodonta africana | 56.71 | 3e-136 | 400 |
| LLPS-Otg-3383 | Otolemur garnettii | 56.71 | 4e-136 | 400 |
| LLPS-Orc-1451 | Oryctolagus cuniculus | 56.71 | 2e-136 | 400 |
| LLPS-Myl-0369 | Myotis lucifugus | 56.71 | 3e-136 | 400 |
| LLPS-Aim-3882 | Ailuropoda melanoleuca | 56.71 | 2e-136 | 400 |
| LLPS-Mum-0552 | Mus musculus | 56.71 | 3e-136 | 400 |
| LLPS-Maf-0057 | Macaca fascicularis | 56.71 | 2e-136 | 400 |
| LLPS-Cea-1038 | Cercocebus atys | 56.71 | 2e-136 | 400 |
| LLPS-Fud-0452 | Fukomys damarensis | 56.71 | 2e-136 | 400 |
| LLPS-Fec-2367 | Felis catus | 56.63 | 6e-136 | 400 |
| LLPS-Sus-3844 | Sus scrofa | 56.63 | 5e-136 | 400 |
| LLPS-Scf-0768 | Scleropages formosus | 56.46 | 6e-133 | 392 |
| LLPS-Pes-1033 | Pelodiscus sinensis | 56.44 | 2e-135 | 399 |
| LLPS-Aon-2078 | Aotus nancymaae | 56.44 | 3e-136 | 400 |
| LLPS-Caj-2367 | Callithrix jacchus | 56.44 | 3e-136 | 400 |
| LLPS-Eqc-1644 | Equus caballus | 56.34 | 3e-124 | 372 |
| LLPS-Gaga-0493 | Gallus gallus | 56.23 | 4e-135 | 397 |
| LLPS-Tag-2823 | Taeniopygia guttata | 56.23 | 4e-135 | 397 |
| LLPS-Meg-1505 | Meleagris gallopavo | 56.23 | 4e-135 | 397 |
| LLPS-Mod-2375 | Monodelphis domestica | 56.23 | 9e-135 | 397 |
| LLPS-Fia-3549 | Ficedula albicollis | 56.23 | 4e-135 | 397 |
| LLPS-Sah-2146 | Sarcophilus harrisii | 56.23 | 1e-134 | 397 |
| LLPS-Ora-0840 | Ornithorhynchus anatinus | 56.16 | 1e-134 | 396 |
| LLPS-Leo-0449 | Lepisosteus oculatus | 56.13 | 9e-134 | 394 |
| LLPS-Asm-0700 | Astyanax mexicanus | 55.99 | 9e-132 | 392 |
| LLPS-Anp-2781 | Anas platyrhynchos | 55.96 | 2e-134 | 396 |
| LLPS-Tut-1412 | Tursiops truncatus | 55.81 | 7e-125 | 370 |
| LLPS-Orn-2169 | Oreochromis niloticus | 55.74 | 3e-131 | 387 |
| LLPS-Dar-0164 | Danio rerio | 55.62 | 2e-133 | 393 |
| LLPS-Icp-0802 | Ictalurus punctatus | 55.62 | 9e-133 | 392 |
| LLPS-Ten-3137 | Tetraodon nigroviridis | 55.46 | 7e-131 | 387 |
| LLPS-Scm-3051 | Scophthalmus maximus | 55.46 | 2e-130 | 385 |
| LLPS-Tar-2841 | Takifugu rubripes | 55.46 | 3e-131 | 387 |
| LLPS-Gaa-2111 | Gasterosteus aculeatus | 55.46 | 2e-130 | 387 |
| LLPS-Orl-1516 | Oryzias latipes | 55.46 | 2e-130 | 385 |
| LLPS-Mal-3748 | Mandrillus leucophaeus | 54.9 | 8e-126 | 374 |
| LLPS-Pof-0323 | Poecilia formosa | 54.62 | 8e-129 | 382 |
| LLPS-Xim-0466 | Xiphophorus maculatus | 54.62 | 8e-129 | 382 |
| LLPS-Paa-0239 | Papio anubis | 54.52 | 1e-125 | 373 |
| LLPS-Lac-1030 | Latimeria chalumnae | 53.93 | 3e-126 | 375 |
| LLPS-Spr-1200 | Sporisorium reilianum | 53.24 | 8e-97 | 301 |
| LLPS-Xet-2557 | Xenopus tropicalis | 52.39 | 2e-124 | 370 |
| LLPS-Chs-0908 | Chlorocebus sabaeus | 51.1 | 2e-125 | 373 |
| LLPS-Rhb-0043 | Rhinopithecus bieti | 50.27 | 8e-122 | 364 |
| LLPS-Drm-1624 | Drosophila melanogaster | 50.0 | 2e-116 | 350 |
| LLPS-Cis-0769 | Ciona savignyi | 49.73 | 1e-111 | 338 |
| LLPS-Mea-1286 | Mesocricetus auratus | 49.18 | 8e-123 | 366 |
| LLPS-Gog-3278 | Gorilla gorilla | 49.18 | 3e-122 | 365 |
| LLPS-Cii-2329 | Ciona intestinalis | 49.17 | 4e-113 | 341 |
| LLPS-Mup-1341 | Mustela putorius furo | 48.63 | 1e-120 | 361 |
| LLPS-Brr-3002 | Brassica rapa | 48.44 | 2e-10 | 63.9 |
| LLPS-Amt-2206 | Amborella trichopoda | 47.24 | 7e-46 | 165 |
| LLPS-Tum-1563 | Tuber melanosporum | 45.22 | 1e-95 | 296 |
| LLPS-Phv-2528 | Phaseolus vulgaris | 45.19 | 1e-60 | 202 |
| LLPS-Abg-0834 | Absidia glauca | 44.93 | 2e-99 | 306 |
| LLPS-Scj-1410 | Schizosaccharomyces japonicus | 44.29 | 1e-97 | 301 |
| LLPS-Lem-0667 | Leptosphaeria maculans | 43.91 | 1e-92 | 289 |
| LLPS-Pug-0005 | Puccinia graminis | 43.68 | 1e-92 | 290 |
| LLPS-Miv-0360 | Microbotryum violaceum | 43.5 | 2e-93 | 292 |
| LLPS-Scp-0433 | Schizosaccharomyces pombe | 43.44 | 5e-100 | 308 |
| LLPS-Asfu-0290 | Aspergillus fumigatus | 43.34 | 4e-94 | 292 |
| LLPS-Nef-0952 | Neosartorya fischeri | 43.34 | 2e-94 | 293 |
| LLPS-Trr-0084 | Trichoderma reesei | 43.3 | 8e-90 | 281 |
| LLPS-Asf-1538 | Aspergillus flavus | 43.11 | 2e-83 | 274 |
| LLPS-Mel-0026 | Melampsora laricipopulina | 43.08 | 5e-95 | 296 |
| LLPS-Asc-0587 | Aspergillus clavatus | 43.06 | 2e-93 | 290 |
| LLPS-Beb-1636 | Beauveria bassiana | 43.02 | 3e-89 | 280 |
| LLPS-Asn-1331 | Aspergillus nidulans | 42.94 | 3e-92 | 288 |
| LLPS-Dos-1175 | Dothistroma septosporum | 42.93 | 9e-89 | 279 |
| LLPS-Trv-0229 | Trichoderma virens | 42.9 | 5e-89 | 279 |
| LLPS-Zyt-0493 | Zymoseptoria tritici | 42.86 | 2e-88 | 278 |
| LLPS-Asni-1565 | Aspergillus niger | 42.78 | 1e-91 | 286 |
| LLPS-Crn-1480 | Cryptococcus neoformans | 42.71 | 2e-96 | 300 |
| LLPS-Usm-1163 | Ustilago maydis | 42.68 | 1e-98 | 306 |
| LLPS-Yal-1389 | Yarrowia lipolytica | 42.63 | 2e-86 | 273 |
| LLPS-Gag-1297 | Gaeumannomyces graminis | 42.61 | 8e-90 | 281 |
| LLPS-Pytr-0976 | Pyrenophora triticirepentis | 42.49 | 6e-91 | 284 |
| LLPS-Ast-1398 | Aspergillus terreus | 42.49 | 2e-93 | 290 |
| LLPS-Pyt-1261 | Pyrenophora teres | 42.49 | 5e-91 | 285 |
| LLPS-Blg-1376 | Blumeria graminis | 42.49 | 4e-85 | 269 |
| LLPS-Put-1335 | Puccinia triticina | 42.38 | 7e-93 | 291 |
| LLPS-Aso-1473 | Aspergillus oryzae | 42.21 | 2e-86 | 273 |
| LLPS-Scs-1040 | Sclerotinia sclerotiorum | 42.17 | 6e-87 | 274 |
| LLPS-Phn-1331 | Phaeosphaeria nodorum | 41.99 | 7e-88 | 278 |
| LLPS-Mao-0724 | Magnaporthe oryzae | 41.93 | 4e-87 | 274 |
| LLPS-Cogr-1658 | Colletotrichum graminicola | 41.87 | 1e-90 | 283 |
| LLPS-Coo-1452 | Colletotrichum orbiculare | 41.87 | 5e-90 | 282 |
| LLPS-Scc-0280 | Schizosaccharomyces cryophilus | 41.85 | 3e-96 | 298 |
| LLPS-Cog-0983 | Colletotrichum gloeosporioides | 41.83 | 2e-90 | 283 |
| LLPS-Fus-0415 | Fusarium solani | 41.76 | 5e-86 | 271 |
| LLPS-Nec-1072 | Neurospora crassa | 41.69 | 5e-91 | 285 |
| LLPS-Ved-0132 | Verticillium dahliae | 41.64 | 4e-90 | 282 |
| LLPS-Sem-2130 | Selaginella moellendorffii | 41.62 | 3e-74 | 242 |
| LLPS-Fuo-0081 | Fusarium oxysporum | 41.48 | 6e-86 | 271 |
| LLPS-Sol-0504 | Solanum lycopersicum | 41.0 | 2e-57 | 204 |
| LLPS-Fuv-1401 | Fusarium verticillioides | 40.91 | 1e-85 | 270 |
| LLPS-Sob-2167 | Sorghum bicolor | 40.78 | 1e-83 | 266 |
| LLPS-Kop-0341 | Komagataella pastoris | 40.66 | 1e-81 | 260 |
| LLPS-Sei-1261 | Setaria italica | 40.5 | 3e-83 | 265 |
| LLPS-Nia-0531 | Nicotiana attenuata | 40.0 | 6e-77 | 248 |
| LLPS-Bro-0777 | Brassica oleracea | 39.94 | 2e-76 | 247 |
| LLPS-Brn-2199 | Brassica napus | 39.94 | 1e-76 | 248 |
| LLPS-Php-1030 | Physcomitrella patens | 39.89 | 8e-78 | 253 |
| LLPS-Arl-0923 | Arabidopsis lyrata | 39.78 | 4e-75 | 244 |
| LLPS-Art-2859 | Arabidopsis thaliana | 39.66 | 1e-72 | 238 |
| LLPS-Gor-0445 | Gossypium raimondii | 39.61 | 1e-75 | 245 |
| LLPS-Met-2364 | Medicago truncatula | 39.56 | 9e-79 | 253 |
| LLPS-Hea-2431 | Helianthus annuus | 39.44 | 4e-74 | 241 |
| LLPS-Tra-1085 | Triticum aestivum | 39.34 | 1e-78 | 253 |
| LLPS-Pot-1876 | Populus trichocarpa | 39.12 | 2e-75 | 244 |
| LLPS-Lep-0877 | Leersia perrieri | 39.11 | 1e-77 | 251 |
| LLPS-Thc-1435 | Theobroma cacao | 39.11 | 7e-75 | 243 |
| LLPS-Asg-0143 | Ashbya gossypii | 39.07 | 4e-73 | 238 |
| LLPS-Brd-0826 | Brachypodium distachyon | 39.06 | 2e-78 | 252 |
| LLPS-Mae-1009 | Manihot esculenta | 38.96 | 2e-74 | 242 |
| LLPS-Viv-0992 | Vitis vinifera | 38.95 | 4e-77 | 249 |
| LLPS-Prp-0222 | Prunus persica | 38.84 | 3e-78 | 252 |
| LLPS-Orbr-0347 | Oryza brachyantha | 38.83 | 3e-77 | 249 |
| LLPS-Glm-1553 | Glycine max | 38.67 | 1e-78 | 253 |
| LLPS-Coc-0388 | Corchorus capsularis | 38.55 | 1e-74 | 243 |
| LLPS-Orm-1729 | Oryza meridionalis | 38.55 | 1e-76 | 249 |
| LLPS-Zem-1804 | Zea mays | 38.46 | 1e-79 | 256 |
| LLPS-Orr-1912 | Oryza rufipogon | 38.27 | 1e-75 | 247 |
| LLPS-Ors-0129 | Oryza sativa | 38.27 | 2e-76 | 247 |
| LLPS-Orgl-1846 | Oryza glumaepatula | 38.27 | 1e-75 | 247 |
| LLPS-Orb-0875 | Oryza barthii | 38.27 | 1e-75 | 247 |
| LLPS-Ori-0691 | Oryza indica | 38.27 | 3e-76 | 246 |
| LLPS-Orni-0974 | Oryza nivara | 38.27 | 1e-75 | 247 |
| LLPS-Hov-1473 | Hordeum vulgare | 38.26 | 2e-70 | 232 |
| LLPS-Cus-1470 | Cucumis sativus | 38.19 | 6e-73 | 238 |
| LLPS-Mua-0378 | Musa acuminata | 38.16 | 3e-73 | 239 |
| LLPS-Via-0017 | Vigna angularis | 38.12 | 1e-79 | 255 |
| LLPS-Dac-1064 | Daucus carota | 37.95 | 1e-75 | 245 |
| LLPS-Vir-1099 | Vigna radiata | 37.92 | 2e-77 | 249 |
| LLPS-Chr-1120 | Chlamydomonas reinhardtii | 37.57 | 7e-33 | 132 |
| LLPS-Sac-1174 | Saccharomyces cerevisiae | 37.2 | 5e-70 | 231 |
| LLPS-Tru-0675 | Triticum urartu | 36.99 | 3e-68 | 226 |
| LLPS-Orp-2305 | Oryza punctata | 32.72 | 6e-43 | 159 |