• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Tar-0733
idh2

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Isocitrate dehydrogenase [NADP]
Gene Name: idh2
Ensembl Gene: ENSTRUG00000006159.2
Ensembl Protein: ENSTRUP00000014969.1
Organism: Takifugu rubripes
Taxa ID: 31033
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAGYLKVLSS  LSRSAATFSR  NPAVLAPAAA  NCQTQRNYMN  RRIKVAQPVV  EMDGDEMTRI  60
61    IWEFIKEKLI  LSNVDVELKY  YDLGLPYRDQ  TDDQVTIDSA  LATKKYSVAV  KCATITPDEA  120
121   RVEEFNLKKM  WKSPNGTIRN  ILGGTVFREP  IICKNIPRLV  PGWTQPITIG  RHAFGDQYRA  180
181   TDFVVDQPGK  FKIIFTPADG  STGKEWEVYD  FPAGGCGMGM  YNTDESITGF  AHSCFQYAIG  240
241   KKWPLYMSTK  NTILKAYDGR  FKDIFQDIFE  KHYKPQFDKL  KIWYEHRLID  DMVAQVLKSS  300
301   GAFVWACKNY  DGDVQSDILA  QGFGSLGLMT  SVLVCPDGKT  IEAEAAHGTV  TRHYREHQKG  360
361   RPTSTNPIAS  IFAWTRGLEH  RGKLDGNDDL  IKFSQTLERV  CVETVESGTM  TKDLAGCIHG  420
421   LSNVKLNEHY  VNTTDFLDAI  KTNLDKALGK  450
Nucleotide CDS Sequence (FASTA)
1     ATGGCTGGAT  ATTTGAAAGT  CCTGAGCTCC  CTTTCGAGGT  CCGCCGCCAC  CTTCTCCAGA  60
61    AACCCCGCGG  TGCTGGCGCC  GGCAGCCGCC  AACTGCCAGA  CGCAAAGAAA  CTATATGAAC  120
121   AGACGCATCA  AGGTGGCCCA  GCCCGTGGTG  GAGATGGACG  GAGACGAGAT  GACCAGGATC  180
181   ATCTGGGAGT  TCATCAAAGA  GAAGCTCATC  CTGAGCAATG  TTGATGTTGA  GCTGAAATAT  240
241   TACGACCTGG  GCCTGCCATA  CCGCGATCAA  ACCGACGACC  AGGTCACCAT  CGATTCCGCC  300
301   CTGGCTACAA  AGAAATACAG  CGTAGCGGTC  AAATGTGCCA  CCATCACCCC  AGACGAGGCC  360
361   CGGGTGGAAG  AGTTTAATCT  GAAGAAGATG  TGGAAGAGCC  CCAACGGCAC  CATCAGGAAC  420
421   ATCCTGGGAG  GCACAGTCTT  CCGTGAGCCA  ATCATCTGCA  AGAACATTCC  CCGGCTCGTT  480
481   CCAGGCTGGA  CGCAGCCCAT  CACCATCGGG  AGACACGCCT  TCGGTGACCA  GTACAGAGCC  540
541   ACCGACTTTG  TTGTGGACCA  GCCTGGGAAA  TTCAAGATCA  TTTTCACTCC  CGCGGATGGA  600
601   AGTACCGGCA  AGGAATGGGA  GGTGTACGAT  TTCCCCGCCG  GTGGCTGTGG  AATGGGCATG  660
661   TACAACACCG  ATGAGTCTAT  CACAGGCTTT  GCACACAGCT  GCTTCCAGTA  TGCGATTGGC  720
721   AAGAAGTGGC  CCCTGTACAT  GAGCACGAAG  AACACCATTC  TCAAAGCCTA  TGACGGCAGA  780
781   TTTAAAGACA  TCTTCCAGGA  CATCTTTGAA  AAACACTACA  AGCCCCAGTT  CGATAAGCTG  840
841   AAGATCTGGT  ACGAGCACAG  GCTAATTGAT  GACATGGTCG  CCCAAGTGCT  GAAATCTTCT  900
901   GGAGCTTTCG  TGTGGGCGTG  CAAGAACTAC  GACGGAGATG  TTCAGTCGGA  CATTCTTGCG  960
961   CAGGGTTTCG  GATCGCTGGG  ATTGATGACG  TCCGTCCTCG  TCTGCCCTGA  TGGCAAAACC  1020
1021  ATCGAGGCTG  AGGCTGCCCA  CGGCACCGTG  ACCAGGCACT  ATCGTGAGCA  CCAGAAGGGA  1080
1081  AGGCCAACCA  GCACCAACCC  CATCGCCAGC  ATCTTTGCAT  GGACCAGAGG  CCTGGAACAC  1140
1141  CGTGGCAAAC  TCGACGGCAA  CGATGACCTT  ATAAAATTCT  CCCAAACCCT  GGAGAGGGTG  1200
1201  TGCGTTGAGA  CCGTAGAAAG  TGGTACAATG  ACCAAGGACC  TTGCAGGATG  CATTCATGGA  1260
1261  CTTTCCAATG  TCAAGCTGAA  CGAGCACTAC  GTCAATACTA  CGGACTTCCT  GGACGCCATC  1320
1321  AAGACAAATC  TGGACAAAGC  TCTGGGCAAG  TGA  1353

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Ten-3075Tetraodon nigroviridis95.560.0 912
LLPS-Orn-0156Oreochromis niloticus95.140.0 896
LLPS-Pof-0365Poecilia formosa94.480.0 892
LLPS-Orl-2856Oryzias latipes94.260.0 892
LLPS-Gaa-2351Gasterosteus aculeatus93.790.0 884
LLPS-Xim-1387Xiphophorus maculatus93.60.0 885
LLPS-Leo-1022Lepisosteus oculatus92.020.0 873
LLPS-Asm-3271Astyanax mexicanus91.740.0 871
LLPS-Scf-3927Scleropages formosus91.150.0 871
LLPS-Urm-3144Ursus maritimus90.370.0 680
LLPS-Meg-0508Meleagris gallopavo90.00.0 636
LLPS-Fia-0857Ficedula albicollis89.970.0 768
LLPS-Mam-3410Macaca mulatta89.470.0 763
LLPS-Lac-0308Latimeria chalumnae89.080.0 679
LLPS-Sah-0715Sarcophilus harrisii89.050.0 780
LLPS-Fud-2394Fukomys damarensis89.050.0 783
LLPS-Tut-1848Tursiops truncatus89.050.0 784
LLPS-Mal-3639Mandrillus leucophaeus89.050.0 781
LLPS-Aim-4259Ailuropoda melanoleuca89.050.0 784
LLPS-Caf-2123Canis familiaris88.890.0 785
LLPS-Loa-1811Loxodonta africana88.810.0 780
LLPS-Anc-0766Anolis carolinensis87.470.0 799
LLPS-Pap-1106Pan paniscus87.350.0 792
LLPS-Scm-2244Scophthalmus maximus86.980.0 832
LLPS-Xet-2971Xenopus tropicalis86.780.0 823
LLPS-Icp-0242Ictalurus punctatus85.450.0 849
LLPS-Gaga-0569Gallus gallus85.430.0 803
LLPS-Cas-2948Carlito syrichta85.370.0 812
LLPS-Ict-0540Ictidomys tridecemlineatus84.920.0 808
LLPS-Bot-4096Bos taurus84.920.0 810
LLPS-Mup-0441Mustela putorius furo84.770.0 806
LLPS-Man-1676Macaca nemestrina84.70.0 810
LLPS-Cap-4581Cavia porcellus84.70.0 804
LLPS-Maf-1727Macaca fascicularis84.70.0 810
LLPS-Chs-1107Chlorocebus sabaeus84.70.0 810
LLPS-Sus-4632Sus scrofa84.70.0 810
LLPS-Cea-1367Cercocebus atys84.70.0 810
LLPS-Paa-1273Papio anubis84.70.0 810
LLPS-Pat-2155Pan troglodytes84.480.0 808
LLPS-Orc-2336Oryctolagus cuniculus84.480.0 807
LLPS-Rhb-4312Rhinopithecus bieti84.480.0 808
LLPS-Poa-0590Pongo abelii84.480.0 808
LLPS-Gog-3800Gorilla gorilla84.480.0 808
LLPS-Fec-3358Felis catus84.360.0 802
LLPS-Hos-0643Homo sapiens84.260.0 806
LLPS-Mum-4480Mus musculus84.260.0 805
LLPS-Caj-1238Callithrix jacchus84.260.0 806
LLPS-Ran-4613Rattus norvegicus84.260.0 803
LLPS-Otg-2869Otolemur garnettii84.040.0 800
LLPS-Eqc-4335Equus caballus84.040.0 804
LLPS-Nol-3714Nomascus leucogenys84.040.0 802
LLPS-Mea-2525Mesocricetus auratus84.040.0 801
LLPS-Dio-3628Dipodomys ordii82.930.0 783
LLPS-Myl-3809Myotis lucifugus82.670.0 773
LLPS-Mod-2712Monodelphis domestica81.490.0 793
LLPS-Aon-3269Aotus nancymaae80.770.0 788
LLPS-Ora-3461Ornithorhynchus anatinus79.40.0 703
LLPS-Cis-0102Ciona savignyi79.270.0 690
LLPS-Cii-0411Ciona intestinalis78.570.0 694
LLPS-Abg-0312Absidia glauca71.080.0 618
LLPS-Mua-1677Musa acuminata70.340.0 594
LLPS-Php-0116Physcomitrella patens70.240.0 597
LLPS-Brn-1369Brassica napus70.20.0 601
LLPS-Cae-2008Caenorhabditis elegans70.020.0 618
LLPS-Bro-1492Brassica oleracea69.950.0 590
LLPS-Orgl-0801Oryza glumaepatula69.610.0 596
LLPS-Met-0759Medicago truncatula69.460.0 598
LLPS-Ors-1098Oryza sativa69.440.0 596
LLPS-Sob-0922Sorghum bicolor69.440.0 594
LLPS-Orbr-0429Oryza brachyantha69.440.0 598
LLPS-Orr-0068Oryza rufipogon69.440.0 596
LLPS-Zem-2436Zea mays69.440.0 591
LLPS-Sei-0654Setaria italica69.440.0 593
LLPS-Sol-2369Solanum lycopersicum69.40.0 593
LLPS-Pot-1248Populus trichocarpa69.360.0 594
LLPS-Orb-1355Oryza barthii69.360.0 595
LLPS-Brr-1548Brassica rapa69.340.0 589
LLPS-Art-0691Arabidopsis thaliana69.270.0 586
LLPS-Vir-0897Vigna radiata69.270.0 596
LLPS-Cus-0461Cucumis sativus69.230.0 592
LLPS-Orm-1255Oryza meridionalis69.190.0 588
LLPS-Org-1330Oryza glaberrima69.190.0 589
LLPS-Ori-0994Oryza indica69.190.0 589
LLPS-Hea-0996Helianthus annuus69.190.0 594
LLPS-Orni-1202Oryza nivara69.190.0 589
LLPS-Sem-2460Selaginella moellendorffii69.140.0 592
LLPS-Lep-2108Leersia perrieri69.120.0 588
LLPS-Prp-0869Prunus persica69.060.0 597
LLPS-Via-1920Vigna angularis69.020.0 595
LLPS-Phv-1039Phaseolus vulgaris68.970.0 591
LLPS-Orp-0216Oryza punctata68.950.0 589
LLPS-Coc-0574Corchorus capsularis68.870.0 594
LLPS-Dac-0559Daucus carota68.860.0 597
LLPS-Glm-1854Glycine max68.780.0 595
LLPS-Thc-2314Theobroma cacao68.630.0 596
LLPS-Nia-0951Nicotiana attenuata68.610.0 594
LLPS-Amt-0771Amborella trichopoda68.320.0 580
LLPS-Miv-0522Microbotryum violaceum68.30.0 574
LLPS-Arl-1135Arabidopsis lyrata68.30.0 596
LLPS-Mae-1858Manihot esculenta68.290.0 597
LLPS-Sot-0130Solanum tuberosum68.20.0 595
LLPS-Gor-0915Gossypium raimondii68.130.0 587
LLPS-Viv-2447Vitis vinifera67.80.0 588
LLPS-Trv-0903Trichoderma virens67.560.0 580
LLPS-Asf-1316Aspergillus flavus67.550.0 570
LLPS-Asfu-1413Aspergillus fumigatus67.480.0 570
LLPS-Fuo-0792Fusarium oxysporum67.40.0 573
LLPS-Fuv-1123Fusarium verticillioides67.40.0 574
LLPS-Tra-2939Triticum aestivum67.40.0 579
LLPS-Ast-1386Aspergillus terreus67.393e-175 507
LLPS-Nef-1424Neosartorya fischeri66.990.0 565
LLPS-Aso-1278Aspergillus oryzae66.990.0 563
LLPS-Fus-0022Fusarium solani66.830.0 568
LLPS-Asc-1674Aspergillus clavatus66.750.0 560
LLPS-Blg-1556Blumeria graminis66.750.0 562
LLPS-Mao-0355Magnaporthe oryzae66.590.0 563
LLPS-Brd-0694Brachypodium distachyon66.590.0 577
LLPS-Dar-3474Danio rerio66.340.0 580
LLPS-Cogr-0254Colletotrichum graminicola66.180.0 565
LLPS-Map-1037Magnaporthe poae65.880.0 574
LLPS-Yal-0857Yarrowia lipolytica65.860.0 558
LLPS-Pytr-0904Pyrenophora triticirepentis65.850.0 553
LLPS-Pyt-0249Pyrenophora teres65.850.0 553
LLPS-Spr-0350Sporisorium reilianum65.770.0 578
LLPS-Tru-0011Triticum urartu65.320.0 570
LLPS-Ved-0383Verticillium dahliae65.180.0 564
LLPS-Gag-0022Gaeumannomyces graminis65.110.0 571
LLPS-Sac-1510Saccharomyces cerevisiae64.860.0 553
LLPS-Scs-0130Sclerotinia sclerotiorum64.760.0 569
LLPS-Kop-0353Komagataella pastoris64.630.0 556
LLPS-Mel-0810Melampsora laricipopulina64.574e-180 516
LLPS-Chr-1711Chlamydomonas reinhardtii64.560.0 608
LLPS-Asg-1267Ashbya gossypii64.390.0 554
LLPS-Asn-0762Aspergillus nidulans64.350.0 576
LLPS-Hov-0561Hordeum vulgare64.130.0 586
LLPS-Tum-1230Tuber melanosporum63.660.0 549
LLPS-Drm-2041Drosophila melanogaster63.570.0 569
LLPS-Coo-1113Colletotrichum orbiculare63.230.0 581
LLPS-Zyt-0366Zymoseptoria tritici63.170.0 556
LLPS-Scj-1583Schizosaccharomyces japonicus62.790.0 568
LLPS-Gas-0858Galdieria sulphuraria62.770.0 536
LLPS-Put-1186Puccinia triticina62.470.0 519
LLPS-Scp-1427Schizosaccharomyces pombe62.410.0 566
LLPS-Lem-1010Leptosphaeria maculans62.00.0 556
LLPS-Dos-0038Dothistroma septosporum61.760.0 554
LLPS-Scc-0485Schizosaccharomyces cryophilus61.070.0 529
LLPS-Usm-0378Ustilago maydis60.590.0 582
LLPS-Chc-0474Chondrus crispus59.63e-176 508
LLPS-Phn-1175Phaeosphaeria nodorum59.377e-165 477
LLPS-Cym-0162Cyanidioschyzon merolae58.580.0 528