• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Mea-2525
Idh2

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Isocitrate dehydrogenase [NADP]
Gene Name: Idh2
Ensembl Gene: ENSMAUG00000019935.1
Ensembl Protein: ENSMAUP00000022535.1
Organism: Mesocricetus auratus
Taxa ID: 10036
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAGYLRAVHS  LCKAPGSARA  WAPAALTVPS  RPEQPRRHYA  DKRIKVEKPV  VEMDGDEMTR  60
61    IIWQFIKEKL  ILPHVDVQLK  YFDLGLPNRD  QTNDQVTIDS  ALATQKYSVA  VKCATITPDE  120
121   ARVEEFKLKK  MWKSPNGTIR  NILGGTVFRE  PIICKNIPRL  VPGWTKPITI  GRHAHGDQYK  180
181   ATDFVVDRSG  TFKMVFTPKD  GSGAKEWEVY  NFPAGGVGMG  MYNTDESISG  FAHSCFQYAI  240
241   QKKWPLYLST  KNTIMKAYDG  RFKDIFQEIF  DKHYKTDFDK  NKIWYEHRLI  DDMVAQVLKS  300
301   SGGFVWACKN  YDGDVQSDIL  AQGFGSLGLM  TSVLVCPDGK  TIEAEAAHGT  VTRHYREHQK  360
361   GRPTSTNPIA  SIFAWTRGLE  HRGKLDGNQD  LIKFAQTLEK  VCVETVESGA  MTKDLAGCIH  420
421   GLSNVKLNEH  FLNTTDFLDT  IKSNLDRALG  KQ  452
Nucleotide CDS Sequence (FASTA)
1     ATGGCCGGTT  ACCTGCGGGC  CGTGCACTCG  CTCTGCAAAG  CCCCTGGCTC  GGCGCGAGCC  60
61    TGGGCACCGG  CCGCCCTGAC  TGTCCCCAGC  AGGCCGGAGC  AGCCACGGCG  CCACTATGCT  120
121   GACAAGAGGA  TCAAGGTGGA  GAAGCCAGTG  GTGGAGATGG  ATGGCGATGA  GATGACCCGC  180
181   ATCATCTGGC  AGTTCATCAA  GGAGAAGCTC  ATCCTGCCTC  ATGTGGATGT  CCAACTCAAG  240
241   TATTTTGACC  TCGGGCTTCC  AAATCGTGAC  CAGACCAATG  ACCAGGTCAC  CATTGACTCT  300
301   GCTCTGGCCA  CCCAGAAGTA  CAGTGTGGCT  GTCAAGTGTG  CCACAATCAC  CCCTGATGAG  360
361   GCTCGTGTGG  AAGAGTTCAA  GCTTAAGAAA  ATGTGGAAGA  GCCCTAATGG  AACCATCAGG  420
421   AACATCCTTG  GGGGAACCGT  ATTCAGAGAG  CCCATCATCT  GCAAAAACAT  CCCCCGTCTT  480
481   GTCCCTGGCT  GGACCAAACC  CATCACCATT  GGCAGGCATG  CCCATGGCGA  CCAGTACAAG  540
541   GCCACAGACT  TTGTGGTAGA  TCGATCTGGC  ACGTTCAAGA  TGGTCTTCAC  CCCAAAGGAC  600
601   GGCAGCGGTG  CCAAGGAATG  GGAGGTGTAC  AACTTCCCTG  CCGGTGGCGT  GGGCATGGGG  660
661   ATGTACAACA  CCGACGAGTC  CATTTCGGGC  TTTGCGCACA  GCTGCTTCCA  GTACGCTATC  720
721   CAGAAGAAGT  GGCCGCTCTA  CTTGAGCACC  AAGAACACCA  TTATGAAGGC  CTATGACGGG  780
781   CGTTTCAAGG  ACATCTTCCA  GGAGATCTTT  GACAAGCACT  ATAAGACTGA  CTTCGACAAG  840
841   AATAAGATCT  GGTACGAGCA  TCGGCTCATT  GACGACATGG  TGGCCCAGGT  GCTCAAGTCT  900
901   TCAGGTGGCT  TTGTGTGGGC  CTGCAAGAAC  TATGACGGAG  ATGTACAGTC  CGACATCCTG  960
961   GCTCAAGGCT  TTGGCTCCCT  TGGCCTGATG  ACATCTGTGC  TGGTCTGCCC  TGATGGGAAG  1020
1021  ACAATTGAGG  CTGAGGCTGC  TCACGGGACA  GTCACCCGCC  ACTACCGAGA  GCACCAGAAG  1080
1081  GGCCGACCCA  CCAGTACCAA  CCCTATCGCC  AGCATCTTTG  CCTGGACGAG  GGGGCTAGAG  1140
1141  CATCGAGGGA  AGCTGGATGG  GAACCAGGAC  CTCATCAAGT  TCGCGCAGAC  TCTGGAGAAG  1200
1201  GTGTGTGTAG  AGACTGTGGA  GAGTGGAGCT  ATGACCAAGG  ACCTGGCTGG  ATGCATCCAT  1260
1261  GGCCTCAGCA  ATGTGAAGCT  GAATGAACAC  TTCCTGAACA  CCACAGACTT  CCTGGACACC  1320
1321  ATTAAGAGCA  ACCTGGACAG  AGCTCTGGGC  AAGCAGTAG  1359

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Fud-2394Fukomys damarensis97.820.0 849
LLPS-Mam-3410Macaca mulatta97.750.0 828
LLPS-Mal-3639Mandrillus leucophaeus97.580.0 849
LLPS-Urm-3144Ursus maritimus97.180.0 727
LLPS-Mum-4480Mus musculus97.120.0 901
LLPS-Ran-4613Rattus norvegicus96.90.0 900
LLPS-Dio-3628Dipodomys ordii96.840.0 841
LLPS-Pap-1106Pan paniscus96.710.0 872
LLPS-Loa-1811Loxodonta africana96.610.0 842
LLPS-Caf-2123Canis familiaris96.370.0 845
LLPS-Sah-0715Sarcophilus harrisii96.370.0 843
LLPS-Tut-1848Tursiops truncatus96.370.0 845
LLPS-Cas-2948Carlito syrichta96.240.0 892
LLPS-Aim-4259Ailuropoda melanoleuca95.870.0 837
LLPS-Rhb-4312Rhinopithecus bieti95.580.0 892
LLPS-Pat-2155Pan troglodytes95.580.0 892
LLPS-Gog-3800Gorilla gorilla95.580.0 892
LLPS-Man-1676Macaca nemestrina95.350.0 889
LLPS-Hos-0643Homo sapiens95.350.0 890
LLPS-Ict-0540Ictidomys tridecemlineatus95.350.0 889
LLPS-Cea-1367Cercocebus atys95.350.0 889
LLPS-Chs-1107Chlorocebus sabaeus95.350.0 889
LLPS-Paa-1273Papio anubis95.350.0 889
LLPS-Nol-3714Nomascus leucogenys95.130.0 888
LLPS-Poa-0590Pongo abelii95.130.0 891
LLPS-Maf-1727Macaca fascicularis95.130.0 889
LLPS-Orc-2336Oryctolagus cuniculus94.910.0 886
LLPS-Eqc-4335Equus caballus94.910.0 882
LLPS-Sus-4632Sus scrofa94.910.0 885
LLPS-Bot-4096Bos taurus94.910.0 885
LLPS-Cap-4581Cavia porcellus94.690.0 879
LLPS-Caj-1238Callithrix jacchus94.690.0 883
LLPS-Fec-3358Felis catus94.680.0 879
LLPS-Otg-2869Otolemur garnettii94.030.0 879
LLPS-Mup-0441Mustela putorius furo94.00.0 874
LLPS-Fia-0857Ficedula albicollis93.750.0 795
LLPS-Meg-0508Meleagris gallopavo93.640.0 659
LLPS-Anc-0766Anolis carolinensis93.410.0 840
LLPS-Myl-3809Myotis lucifugus92.430.0 825
LLPS-Lac-0308Latimeria chalumnae89.920.0 680
LLPS-Gaga-0569Gallus gallus89.730.0 828
LLPS-Aon-3269Aotus nancymaae89.550.0 854
LLPS-Mod-2712Monodelphis domestica88.110.0 843
LLPS-Ora-3461Ornithorhynchus anatinus85.710.0 750
LLPS-Xet-2971Xenopus tropicalis85.050.0 805
LLPS-Leo-1022Lepisosteus oculatus84.960.0 802
LLPS-Orn-0156Oreochromis niloticus84.510.0 794
LLPS-Pof-0365Poecilia formosa84.510.0 795
LLPS-Scf-3927Scleropages formosus84.510.0 798
LLPS-Xim-1387Xiphophorus maculatus84.070.0 790
LLPS-Ten-3075Tetraodon nigroviridis84.040.0 798
LLPS-Orl-2856Oryzias latipes83.630.0 790
LLPS-Tar-0733Takifugu rubripes83.590.0 795
LLPS-Gaa-2351Gasterosteus aculeatus82.670.0 787
LLPS-Asm-3271Astyanax mexicanus82.630.0 784
LLPS-Scm-2244Scophthalmus maximus81.460.0 779
LLPS-Cis-0102Ciona savignyi77.640.0 691
LLPS-Cii-0411Ciona intestinalis77.110.0 685
LLPS-Icp-0242Ictalurus punctatus76.970.0 765
LLPS-Scs-0130Sclerotinia sclerotiorum72.150.0 566
LLPS-Mua-1677Musa acuminata71.50.0 598
LLPS-Cae-2008Caenorhabditis elegans71.360.0 615
LLPS-Asf-1316Aspergillus flavus70.930.0 560
LLPS-Abg-1928Absidia glauca70.860.0 609
LLPS-Asn-0762Aspergillus nidulans70.740.0 563
LLPS-Sem-2460Selaginella moellendorffii70.270.0 601
LLPS-Sol-2369Solanum lycopersicum70.050.0 599
LLPS-Php-0116Physcomitrella patens70.00.0 592
LLPS-Zem-2436Zea mays69.90.0 593
LLPS-Prp-0869Prunus persica69.80.0 602
LLPS-Aso-1278Aspergillus oryzae69.760.0 548
LLPS-Hea-0996Helianthus annuus69.730.0 600
LLPS-Nia-0951Nicotiana attenuata69.590.0 601
LLPS-Pot-1248Populus trichocarpa69.590.0 597
LLPS-Sob-0922Sorghum bicolor69.420.0 592
LLPS-Sei-0654Setaria italica69.420.0 592
LLPS-Bro-1492Brassica oleracea69.360.0 586
LLPS-Orgl-0801Oryza glumaepatula69.340.0 593
LLPS-Brn-1369Brassica napus69.290.0 599
LLPS-Dac-0559Daucus carota69.250.0 598
LLPS-Met-0759Medicago truncatula69.210.0 595
LLPS-Ors-1098Oryza sativa69.170.0 593
LLPS-Orr-0068Oryza rufipogon69.170.0 593
LLPS-Orb-1355Oryza barthii69.10.0 592
LLPS-Orm-1255Oryza meridionalis69.020.0 586
LLPS-Orbr-0429Oryza brachyantha68.930.0 592
LLPS-Org-1330Oryza glaberrima68.930.0 588
LLPS-Orni-1202Oryza nivara68.930.0 588
LLPS-Ori-0994Oryza indica68.930.0 588
LLPS-Lep-2108Leersia perrieri68.860.0 586
LLPS-Viv-2447Vitis vinifera68.840.0 602
LLPS-Sot-0130Solanum tuberosum68.840.0 601
LLPS-Amt-0771Amborella trichopoda68.80.0 585
LLPS-Thc-2314Theobroma cacao68.80.0 592
LLPS-Orp-0216Oryza punctata68.780.0 587
LLPS-Brr-1548Brassica rapa68.770.0 585
LLPS-Art-0691Arabidopsis thaliana68.690.0 583
LLPS-Via-0664Vigna angularis68.690.0 602
LLPS-Arl-1135Arabidopsis lyrata68.630.0 598
LLPS-Chr-1711Chlamydomonas reinhardtii68.630.0 611
LLPS-Gor-0915Gossypium raimondii68.610.0 590
LLPS-Coc-0574Corchorus capsularis68.60.0 598
LLPS-Dar-3474Danio rerio68.560.0 595
LLPS-Mae-1858Manihot esculenta68.450.0 598
LLPS-Glm-2375Glycine max68.450.0 597
LLPS-Phv-1039Phaseolus vulgaris68.380.0 588
LLPS-Vir-0897Vigna radiata68.20.0 590
LLPS-Hov-0561Hordeum vulgare67.880.0 585
LLPS-Tra-2939Triticum aestivum67.880.0 582
LLPS-Blg-1556Blumeria graminis67.730.0 572
LLPS-Cogr-0254Colletotrichum graminicola67.070.0 572
LLPS-Brd-0694Brachypodium distachyon66.830.0 572
LLPS-Cus-0461Cucumis sativus66.820.0 596
LLPS-Coo-1113Colletotrichum orbiculare66.750.0 571
LLPS-Fus-0022Fusarium solani66.340.0 563
LLPS-Miv-0522Microbotryum violaceum66.340.0 561
LLPS-Trv-0903Trichoderma virens66.340.0 568
LLPS-Yal-0857Yarrowia lipolytica66.340.0 564
LLPS-Fuo-0792Fusarium oxysporum66.190.0 574
LLPS-Fuv-1123Fusarium verticillioides66.190.0 573
LLPS-Lem-1010Leptosphaeria maculans66.180.0 557
LLPS-Ved-0383Verticillium dahliae66.110.0 566
LLPS-Asfu-1413Aspergillus fumigatus66.010.0 561
LLPS-Pytr-0904Pyrenophora triticirepentis65.850.0 555
LLPS-Map-1037Magnaporthe poae65.850.0 561
LLPS-Gag-0022Gaeumannomyces graminis65.850.0 561
LLPS-Pyt-0249Pyrenophora teres65.850.0 556
LLPS-Tru-0011Triticum urartu65.80.0 573
LLPS-Asc-1674Aspergillus clavatus65.530.0 552
LLPS-Drm-2041Drosophila melanogaster65.350.0 566
LLPS-Ast-1386Aspergillus terreus65.221e-168 490
LLPS-Scj-1583Schizosaccharomyces japonicus65.120.0 570
LLPS-Mel-0810Melampsora laricipopulina65.090.0 523
LLPS-Nef-1424Neosartorya fischeri65.040.0 550
LLPS-Usm-0378Ustilago maydis64.720.0 575
LLPS-Scp-1427Schizosaccharomyces pombe64.550.0 564
LLPS-Dos-0038Dothistroma septosporum64.390.0 562
LLPS-Kop-0353Komagataella pastoris64.390.0 556
LLPS-Sac-1510Saccharomyces cerevisiae64.370.0 546
LLPS-Asg-1267Ashbya gossypii64.160.0 560
LLPS-Zyt-0366Zymoseptoria tritici63.920.0 555
LLPS-Tum-1230Tuber melanosporum63.90.0 550
LLPS-Mao-0355Magnaporthe oryzae63.790.0 553
LLPS-Spr-0350Sporisorium reilianum63.770.0 571
LLPS-Put-1186Puccinia triticina62.890.0 526
LLPS-Scc-0485Schizosaccharomyces cryophilus62.290.0 536
LLPS-Chc-0474Chondrus crispus60.859e-180 518
LLPS-Gas-0858Galdieria sulphuraria60.70.0 542
LLPS-Phn-1175Phaeosphaeria nodorum59.84e-166 480
LLPS-Cym-0162Cyanidioschyzon merolae58.640.0 529