• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Dio-3628
Idh2

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Isocitrate dehydrogenase [NADP]
Gene Name: Idh2
Ensembl Gene: ENSDORG00000014489.2
Ensembl Protein: ENSDORP00000013623.2
Organism: Dipodomys ordii
Taxa ID: 10020
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ SEQUENCE

Protein Sequence (FASTA)
1     WAGTLAALIG  LCRRGRGGTL  SPSHLPSCDL  PRLLLDADKR  IKVEKPVVEM  DGDEMTRIIW  60
61    QFIKEKLILP  HVDVQLKYFD  LGLPNRDQTN  DQVTIDSALA  TQKYSVAVKC  ATITPDEARV  120
121   EEFKLKKMWK  SPNGTIRNIL  GGTVFREPII  CKNIPRLVPG  WTKPITIGRH  AHGDQYKSTD  180
181   FVVDRAGTFK  VVFTPKDGSG  AKEWEVYNFP  AGGVGMGMYN  TDESISGFAH  SCFQYAIQKK  240
241   WPLYLSTKNT  ILKAYDGRFK  DLFQEIFDKH  YKTDFDKHKI  WYEHRLIDDM  VAQVLKSSGG  300
301   FVWACKNYDG  DVQSDILAQG  FGSLGLMTSV  LVCPDGKTIE  AEAAHGTVTR  HYREHQKGRP  360
361   TSTNPIASIF  AWTRGLEHRG  KLDGNQDLIR  FAQTLEKVCV  ETVEGGAMTK  DLAGCIHGLS  420
421   NVKLNEHYLN  TTDFLDAIQT  NLDRALGQP  449
Nucleotide CDS Sequence (FASTA)
1     TGGGCAGGGA  CACTGGCTGC  GCTGATCGGC  TTGTGCAGGA  GGGGGAGGGG  GGGAACGCTG  60
61    TCCCCCTCCC  ACCTGCCCAG  CTGTGACCTG  CCCCGCCTGC  TGCTAGATGC  TGACAAGAGG  120
121   ATCAAGGTGG  AGAAGCCGGT  GGTGGAGATG  GACGGTGACG  AGATGACCCG  AATCATTTGG  180
181   CAGTTCATTA  AGGAGAAGCT  CATCCTGCCC  CATGTGGATG  TCCAGCTCAA  GTACTTCGAC  240
241   CTCGGGCTCC  CGAACCGTGA  CCAGACCAAT  GACCAGGTCA  CCATCGACTC  CGCACTGGCC  300
301   ACCCAGAAGT  ACAGTGTCGC  CGTCAAGTGC  GCCACCATCA  CCCCGGACGA  GGCCCGCGTG  360
361   GAAGAATTCA  AGCTGAAGAA  GATGTGGAAG  AGCCCCAACG  GAACCATCCG  GAACATCCTC  420
421   GGGGGGACTG  TCTTCCGAGA  GCCCATCATT  TGCAAAAACA  TCCCCCGGCT  TGTCCCGGGC  480
481   TGGACCAAAC  CCATCACCAT  CGGCAGGCAC  GCCCACGGCG  ATCAGTACAA  GTCCACAGAC  540
541   TTCGTGGTGG  ACCGGGCTGG  CACGTTCAAG  GTGGTCTTCA  CCCCCAAGGA  TGGCAGCGGT  600
601   GCCAAGGAGT  GGGAGGTGTA  CAACTTCCCC  GCGGGCGGCG  TGGGCATGGG  CATGTACAAT  660
661   ACGGACGAGT  CCATCTCGGG  CTTCGCCCAC  AGCTGCTTCC  AGTACGCCAT  TCAGAAGAAG  720
721   TGGCCGCTGT  ACCTGAGCAC  CAAGAACACC  ATTCTGAAGG  CCTACGACGG  GCGGTTCAAG  780
781   GACCTCTTCC  AGGAGATCTT  TGACAAGCAC  TATAAGACCG  ACTTCGACAA  GCACAAGATC  840
841   TGGTACGAGC  ACCGACTCAT  CGACGACATG  GTGGCTCAGG  TGCTCAAGTC  CTCGGGCGGC  900
901   TTTGTGTGGG  CCTGTAAGAA  TTACGACGGA  GACGTGCAGT  CAGACATCTT  GGCGCAGGGC  960
961   TTTGGTTCTC  TGGGTCTGAT  GACGTCTGTG  CTTGTCTGCC  CCGATGGGAA  GACGATCGAG  1020
1021  GCGGAGGCTG  CCCATGGGAC  TGTCACCCGC  CATTACCGGG  AGCACCAGAA  GGGCCGGCCT  1080
1081  ACCAGCACCA  ACCCCATCGC  CAGCATCTTT  GCCTGGACGC  GGGGCCTGGA  GCACCGCGGC  1140
1141  AAGCTGGACG  GGAACCAGGA  CCTCATCAGG  TTCGCTCAGA  CCCTGGAGAA  GGTGTGCGTG  1200
1201  GAGACCGTGG  AGGGCGGAGC  CATGACCAAA  GACCTGGCTG  GCTGCATCCA  CGGCCTGAGC  1260
1261  AACGTGAAGC  TGAATGAACA  CTACCTGAAC  ACCACAGACT  TCCTGGACGC  CATCCAGACC  1320
1321  AACCTGGACA  GAGCCCTGGG  CCAGCCCTAG  1350

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Fud-2394Fukomys damarensis96.60.0 838
LLPS-Mam-3410Macaca mulatta96.240.0 812
LLPS-Sah-0715Sarcophilus harrisii95.880.0 835
LLPS-Caf-2123Canis familiaris95.630.0 835
LLPS-Urm-3144Ursus maritimus95.590.0 728
LLPS-Tut-1848Tursiops truncatus95.390.0 834
LLPS-Mod-2712Monodelphis domestica95.160.0 829
LLPS-Loa-1811Loxodonta africana95.150.0 828
LLPS-Aim-4259Ailuropoda melanoleuca94.710.0 833
LLPS-Pap-1106Pan paniscus93.460.0 837
LLPS-Mal-3639Mandrillus leucophaeus93.090.0 843
LLPS-Fia-0857Ficedula albicollis92.480.0 784
LLPS-Myl-3809Myotis lucifugus92.380.0 817
LLPS-Meg-0508Meleagris gallopavo91.790.0 648
LLPS-Mum-4480Mus musculus91.570.0 847
LLPS-Gaga-0569Gallus gallus91.50.0 801
LLPS-Ran-4613Rattus norvegicus91.350.0 845
LLPS-Mea-2525Mesocricetus auratus91.350.0 845
LLPS-Ict-0540Ictidomys tridecemlineatus91.350.0 846
LLPS-Bot-4096Bos taurus91.130.0 848
LLPS-Cas-2948Carlito syrichta91.130.0 845
LLPS-Anc-0766Anolis carolinensis91.120.0 813
LLPS-Eqc-4335Equus caballus90.690.0 842
LLPS-Orc-2336Oryctolagus cuniculus90.690.0 843
LLPS-Sus-4632Sus scrofa90.470.0 845
LLPS-Gog-3800Gorilla gorilla90.470.0 840
LLPS-Pat-2155Pan troglodytes90.470.0 840
LLPS-Fec-3358Felis catus90.470.0 841
LLPS-Otg-2869Otolemur garnettii90.470.0 839
LLPS-Rhb-4312Rhinopithecus bieti90.470.0 840
LLPS-Cap-4581Cavia porcellus90.440.0 838
LLPS-Caj-1238Callithrix jacchus90.240.0 837
LLPS-Hos-0643Homo sapiens90.240.0 838
LLPS-Paa-1273Papio anubis90.220.0 839
LLPS-Maf-1727Macaca fascicularis90.220.0 840
LLPS-Chs-1107Chlorocebus sabaeus90.220.0 839
LLPS-Cea-1367Cercocebus atys90.220.0 839
LLPS-Man-1676Macaca nemestrina90.220.0 839
LLPS-Poa-0590Pongo abelii90.020.0 838
LLPS-Nol-3714Nomascus leucogenys89.80.0 835
LLPS-Mup-0441Mustela putorius furo89.140.0 831
LLPS-Scm-2244Scophthalmus maximus86.170.0 764
LLPS-Aon-3269Aotus nancymaae85.710.0 823
LLPS-Ora-3461Ornithorhynchus anatinus85.580.0 728
LLPS-Leo-1022Lepisosteus oculatus84.670.0 791
LLPS-Xet-2971Xenopus tropicalis83.920.0 786
LLPS-Ten-3075Tetraodon nigroviridis83.590.0 787
LLPS-Orn-0156Oreochromis niloticus83.370.0 778
LLPS-Pof-0365Poecilia formosa83.190.0 777
LLPS-Scf-3927Scleropages formosus83.150.0 785
LLPS-Tar-0733Takifugu rubripes82.930.0 783
LLPS-Asm-3271Astyanax mexicanus82.770.0 773
LLPS-Xim-1387Xiphophorus maculatus82.480.0 772
LLPS-Gaa-2351Gasterosteus aculeatus82.220.0 775
LLPS-Orl-2856Oryzias latipes82.040.0 775
LLPS-Lac-0308Latimeria chalumnae81.590.0 674
LLPS-Cis-0102Ciona savignyi77.560.0 679
LLPS-Icp-0242Ictalurus punctatus77.080.0 754
LLPS-Cii-0411Ciona intestinalis77.070.0 676
LLPS-Mua-1677Musa acuminata71.250.0 595
LLPS-Cae-2008Caenorhabditis elegans71.050.0 615
LLPS-Sol-2369Solanum lycopersicum70.30.0 598
LLPS-Sem-2036Selaginella moellendorffii70.020.0 597
LLPS-Php-0116Physcomitrella patens70.00.0 589
LLPS-Hea-0996Helianthus annuus69.930.0 597
LLPS-Nia-0951Nicotiana attenuata69.930.0 600
LLPS-Zem-2436Zea mays69.90.0 590
LLPS-Pot-1248Populus trichocarpa69.830.0 596
LLPS-Abg-1928Absidia glauca69.660.0 607
LLPS-Via-0664Vigna angularis69.630.0 599
LLPS-Sei-0654Setaria italica69.420.0 590
LLPS-Sob-0922Sorghum bicolor69.420.0 589
LLPS-Bro-1492Brassica oleracea69.360.0 583
LLPS-Orgl-0801Oryza glumaepatula69.340.0 591
LLPS-Brn-1369Brassica napus69.290.0 598
LLPS-Met-0759Medicago truncatula69.210.0 591
LLPS-Sot-0130Solanum tuberosum69.170.0 600
LLPS-Orr-0068Oryza rufipogon69.170.0 591
LLPS-Ors-1098Oryza sativa69.170.0 591
LLPS-Orb-1355Oryza barthii69.10.0 590
LLPS-Viv-2447Vitis vinifera69.040.0 597
LLPS-Orm-1255Oryza meridionalis69.020.0 583
LLPS-Glm-2375Glycine max68.950.0 593
LLPS-Ori-0994Oryza indica68.930.0 585
LLPS-Orni-1202Oryza nivara68.930.0 585
LLPS-Org-1330Oryza glaberrima68.930.0 585
LLPS-Orbr-0429Oryza brachyantha68.930.0 589
LLPS-Phv-1039Phaseolus vulgaris68.870.0 588
LLPS-Lep-2108Leersia perrieri68.860.0 583
LLPS-Gor-0915Gossypium raimondii68.860.0 588
LLPS-Dac-0559Daucus carota68.840.0 595
LLPS-Thc-2314Theobroma cacao68.80.0 589
LLPS-Amt-0771Amborella trichopoda68.80.0 582
LLPS-Orp-0216Oryza punctata68.780.0 585
LLPS-Prp-0869Prunus persica68.70.0 599
LLPS-Vir-0897Vigna radiata68.690.0 589
LLPS-Mae-1858Manihot esculenta68.690.0 597
LLPS-Arl-1135Arabidopsis lyrata68.630.0 596
LLPS-Art-2459Arabidopsis thaliana68.630.0 597
LLPS-Brr-1548Brassica rapa68.520.0 581
LLPS-Dar-3474Danio rerio68.40.0 590
LLPS-Tra-2939Triticum aestivum67.880.0 579
LLPS-Cus-0461Cucumis sativus67.80.0 591
LLPS-Brd-0694Brachypodium distachyon66.830.0 569
LLPS-Yal-0857Yarrowia lipolytica66.590.0 563
LLPS-Ved-0383Verticillium dahliae66.590.0 563
LLPS-Fuv-1123Fusarium verticillioides66.350.0 572
LLPS-Fuo-0792Fusarium oxysporum66.350.0 572
LLPS-Coc-0574Corchorus capsularis66.280.0 597
LLPS-Cogr-0254Colletotrichum graminicola66.190.0 572
LLPS-Trv-0903Trichoderma virens66.180.0 567
LLPS-Miv-0522Microbotryum violaceum66.090.0 559
LLPS-Hov-0561Hordeum vulgare65.970.0 582
LLPS-Scj-1583Schizosaccharomyces japonicus65.930.0 570
LLPS-Chr-1711Chlamydomonas reinhardtii65.830.0 612
LLPS-Tru-0011Triticum urartu65.80.0 570
LLPS-Mel-0810Melampsora laricipopulina65.620.0 524
LLPS-Pyt-0249Pyrenophora teres65.530.0 554
LLPS-Asc-1674Aspergillus clavatus65.530.0 550
LLPS-Pytr-0904Pyrenophora triticirepentis65.530.0 554
LLPS-Asn-0762Aspergillus nidulans65.380.0 560
LLPS-Fus-0022Fusarium solani65.240.0 564
LLPS-Asf-1316Aspergillus flavus65.230.0 558
LLPS-Ast-1386Aspergillus terreus65.224e-168 489
LLPS-Gag-0022Gaeumannomyces graminis65.210.0 558
LLPS-Dos-0038Dothistroma septosporum65.210.0 558
LLPS-Nef-1424Neosartorya fischeri65.040.0 548
LLPS-Asfu-1413Aspergillus fumigatus64.990.0 559
LLPS-Asg-1267Ashbya gossypii64.890.0 561
LLPS-Scp-1427Schizosaccharomyces pombe64.790.0 565
LLPS-Drm-2041Drosophila melanogaster64.760.0 559
LLPS-Usm-0378Ustilago maydis64.650.0 573
LLPS-Zyt-0366Zymoseptoria tritici64.560.0 551
LLPS-Scs-0130Sclerotinia sclerotiorum64.50.0 565
LLPS-Map-1037Magnaporthe poae64.490.0 563
LLPS-Kop-0353Komagataella pastoris64.390.0 554
LLPS-Sac-1510Saccharomyces cerevisiae64.370.0 546
LLPS-Aso-1278Aspergillus oryzae64.20.0 546
LLPS-Blg-1556Blumeria graminis64.120.0 572
LLPS-Lem-1010Leptosphaeria maculans63.490.0 557
LLPS-Mao-0355Magnaporthe oryzae63.460.0 550
LLPS-Tum-1230Tuber melanosporum63.410.0 546
LLPS-Coo-1113Colletotrichum orbiculare63.370.0 573
LLPS-Put-1186Puccinia triticina63.370.0 526
LLPS-Spr-0350Sporisorium reilianum62.620.0 572
LLPS-Scc-0485Schizosaccharomyces cryophilus62.290.0 535
LLPS-Chc-0474Chondrus crispus60.855e-179 516
LLPS-Gas-0858Galdieria sulphuraria60.830.0 540
LLPS-Cym-0162Cyanidioschyzon merolae59.370.0 530
LLPS-Phn-1175Phaeosphaeria nodorum59.028e-165 477