• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Sus-3723
SEC23B

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Protein transport protein SEC23
Gene Name: SEC23B
Ensembl Gene: ENSSSCG00000007097.3
Ensembl Protein: ENSSSCP00000007560.2
Organism: Sus scrofa
Taxa ID: 9823
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MATYLEFIQQ  NEERDGVRFS  WNVWPSSRLE  ATRMVVPLAC  LLTPLKERPD  LPPVQYEPVL  60
61    CSRPTCKAIL  NPLCQVDYRA  KLWACNFCFQ  RNQFPPAYAG  ISEVNQPAEL  MPQFSTIEYV  120
121   IQRGAQSPLI  FLYVVDTCLE  EDDLQALKES  LQMSLSLLPP  DALVGLITFG  RMVQVHELSC  180
181   EGISKSYVFR  GTKDLTAKQI  QDMLGLTKPA  MPMQPARPAQ  PQDQPFISSR  FLQPVHKIDM  240
241   NLTDLLGELQ  RDPWPVTQGK  RPLRSTGVAL  SIAVGLLEGT  FPNTGARIML  FTGGPPTQGP  300
301   GMVVGDELKV  PIRSWHDIEK  DNARFMKKAT  KHYEMLANRT  AANGHCIDIY  ACALDQTGLL  360
361   EMKCCTNLTG  GHMVMGDSFN  TSLFKQTFQR  IFSKDFNGNF  RMAFGATLEV  KTSRELKIAG  420
421   AIGPCVSLNM  RGPCVSENEL  GVGGTSQWKI  CGLDPTSTLG  IYFEVVNQHN  APVPQGGRGA  480
481   IQFVTHYQHS  STQRRIRVTT  IARNWADAQS  QLKHIEAAFD  QEAAAVLMAR  LGVFRTESEE  540
541   GPDVLRWLDR  QLIRLCQKFG  QYNKEDPTSF  RLSDSFSLYP  QFMFHLRRSP  FLQVFNNSPD  600
601   ESSYYRHHFA  RQDLTQSLIM  IQPILYSYSF  HGPPEPVLLD  SSSILADRIL  LMDTFFQIVI  660
661   YLGETIAQWR  KAGYQDMPEY  ENFKHLLQAP  LDDAQEILQA  RFPMPRYINT  EHGGSQARFL  720
721   LSKVNPSQTH  NNLYAWGQET  GAPILTDDVS  LQVFMDHLKK  LAVSSAC  767
Nucleotide CDS Sequence (FASTA)
1     ATGGCAACAT  ACTTGGAGTT  CATTCAGCAG  AATGAAGAAC  GTGATGGTGT  ACGTTTCAGT  60
61    TGGAATGTGT  GGCCTTCCAG  CCGCCTCGAG  GCTACACGAA  TGGTTGTTCC  CCTGGCTTGT  120
121   CTCCTGACTC  CTTTAAAAGA  ACGTCCAGAC  CTGCCTCCTG  TGCAGTATGA  ACCTGTGCTT  180
181   TGCAGCAGGC  CAACTTGCAA  AGCCATTCTC  AACCCACTTT  GTCAGGTTGA  TTATCGAGCA  240
241   AAACTTTGGG  CGTGTAATTT  CTGTTTCCAG  AGAAATCAGT  TTCCTCCAGC  TTACGCAGGC  300
301   ATATCTGAGG  TTAATCAGCC  TGCTGAACTG  ATGCCCCAGT  TTTCTACAAT  TGAGTACGTG  360
361   ATACAGCGAG  GTGCCCAGTC  CCCTCTGATC  TTCCTCTATG  TGGTGGACAC  GTGCCTGGAA  420
421   GAAGATGACC  TGCAGGCCCT  CAAGGAGTCC  CTGCAGATGT  CCCTGAGTCT  CCTTCCCCCG  480
481   GATGCTCTGG  TGGGTTTGAT  CACGTTTGGG  AGGATGGTGC  AGGTTCATGA  ACTCAGCTGC  540
541   GAGGGAATCT  CCAAGAGTTA  CGTCTTCCGG  GGGACCAAGG  ATTTAACGGC  AAAGCAAATA  600
601   CAGGACATGC  TGGGCCTGAC  CAAGCCTGCT  ATGCCCATGC  AGCCAGCACG  ACCCGCTCAG  660
661   CCGCAGGACC  AACCTTTCAT  TTCAAGCAGA  TTCCTGCAGC  CCGTTCACAA  GATCGACATG  720
721   AACCTCACTG  ATCTTCTCGG  GGAGCTGCAG  AGGGACCCAT  GGCCCGTAAC  CCAGGGGAAG  780
781   AGACCTTTGC  GATCCACTGG  CGTTGCTTTG  TCCATCGCTG  TTGGCTTGTT  GGAGGGCACT  840
841   TTTCCAAACA  CGGGAGCCAG  GATTATGCTG  TTTACCGGGG  GTCCTCCAAC  CCAAGGACCT  900
901   GGCATGGTGG  TTGGAGATGA  ATTAAAGGTT  CCTATTCGTT  CTTGGCATGA  TATTGAGAAA  960
961   GATAACGCGC  GTTTCATGAA  AAAGGCAACC  AAGCACTACG  AGATGCTTGC  TAACCGAACA  1020
1021  GCTGCAAATG  GTCACTGCAT  TGATATTTAT  GCTTGTGCCC  TTGATCAGAC  TGGACTTTTG  1080
1081  GAGATGAAGT  GTTGCACAAA  TCTTACTGGA  GGCCACATGG  TAATGGGAGA  TTCTTTCAAC  1140
1141  ACTTCTCTCT  TCAAGCAGAC  ATTCCAAAGA  ATTTTCAGTA  AAGATTTTAA  TGGCAATTTC  1200
1201  CGAATGGCAT  TTGGCGCCAC  TTTGGAAGTA  AAGACCTCTC  GGGAACTGAA  GATCGCAGGA  1260
1261  GCCATCGGAC  CTTGTGTGTC  TCTGAACATG  AGAGGACCAT  GTGTATCAGA  AAATGAGCTT  1320
1321  GGCGTTGGTG  GCACGAGTCA  GTGGAAGATC  TGTGGCCTGG  ATCCCACATC  TACACTTGGC  1380
1381  ATCTACTTTG  AAGTGGTCAA  TCAGCACAAC  GCCCCAGTCC  CGCAGGGAGG  GAGAGGCGCC  1440
1441  ATCCAGTTTG  TCACACACTA  TCAACACTCC  AGCACCCAGA  GGCGCATCCG  CGTGACCACC  1500
1501  ATCGCCCGAA  ATTGGGCAGA  TGCGCAGAGC  CAGCTCAAGC  ACATAGAGGC  TGCATTTGAC  1560
1561  CAGGAGGCCG  CGGCAGTCCT  GATGGCACGG  CTGGGAGTGT  TCCGCACAGA  GTCGGAGGAG  1620
1621  GGCCCAGATG  TGCTCCGGTG  GCTGGACCGA  CAGCTCATCC  GACTGTGTCA  GAAGTTTGGA  1680
1681  CAGTATAACA  AAGAAGACCC  CACTTCTTTT  AGGTTATCAG  ATTCCTTCTC  CCTGTACCCT  1740
1741  CAGTTCATGT  TCCATCTTAG  AAGATCTCCG  TTTCTTCAAG  TGTTTAACAA  CAGTCCTGAT  1800
1801  GAATCATCGT  ATTATCGACA  CCACTTTGCC  CGACAGGATC  TAACCCAGTC  CCTCATCATG  1860
1861  ATCCAGCCCA  TTCTCTACTC  CTATTCATTC  CATGGGCCTC  CGGAGCCCGT  GCTCCTGGAC  1920
1921  AGCAGCAGCA  TTCTGGCTGA  TAGGATCCTC  CTGATGGATA  CGTTCTTCCA  AATTGTCATT  1980
1981  TATCTCGGTG  AGACAATAGC  CCAGTGGCGG  AAAGCTGGGT  ACCAGGACAT  GCCCGAATAT  2040
2041  GAAAACTTCA  AGCATCTTCT  TCAGGCCCCG  CTGGACGATG  CTCAGGAAAT  CTTGCAGGCG  2100
2101  CGCTTCCCAA  TGCCGCGTTA  CATCAACACG  GAGCATGGAG  GCAGTCAGGC  TCGATTCCTT  2160
2161  TTGTCTAAAG  TGAATCCATC  TCAGACACAC  AATAACCTGT  ATGCTTGGGG  ACAGGAGACG  2220
2221  GGAGCACCCA  TCCTTACAGA  TGACGTTAGC  CTGCAGGTGT  TCATGGACCA  TCTGAAGAAA  2280
2281  CTGGCTGTCT  CCAGTGCCTG  TTAA  2304

▼ KEYWORD

ID
Family
Complete proteome
Cytoplasm
Cytoplasmic vesicle
Endoplasmic reticulum
ER-Golgi transport
Membrane
Metal-binding
Protein transport
Proteomics identification
Reference proteome
Transport
Zinc

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
COPII vesicle coat
Cellular Component
Cytosol
Cellular Component
Endoplasmic reticulum exit site
Cellular Component
Endoplasmic reticulum membrane
Cellular Component
Golgi membrane
Cellular Component
Perinuclear region of cytoplasm
Molecular Function
GTPase activator activity
Molecular Function
Zinc ion binding
Biological Process
COPII-coated vesicle cargo loading
Biological Process
Intracellular protein transport

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Urm-1170Ursus maritimus97.910.01540
LLPS-Mup-3414Mustela putorius furo97.780.01540
LLPS-Ict-4276Ictidomys tridecemlineatus97.780.01544
LLPS-Gog-3796Gorilla gorilla97.520.01538
LLPS-Poa-3291Pongo abelii97.520.01538
LLPS-Caf-2412Canis familiaris97.520.01541
LLPS-Hos-1741Homo sapiens97.520.01538
LLPS-Pat-2689Pan troglodytes97.390.01540
LLPS-Pap-4178Pan paniscus97.390.01540
LLPS-Paa-4444Papio anubis97.260.01538
LLPS-Mal-1565Mandrillus leucophaeus97.260.01538
LLPS-Ova-0210Ovis aries97.260.01532
LLPS-Maf-3127Macaca fascicularis97.260.01538
LLPS-Mum-4028Mus musculus97.260.01534
LLPS-Man-3909Macaca nemestrina97.260.01538
LLPS-Fec-3847Felis catus97.260.01537
LLPS-Cea-4230Cercocebus atys97.130.01535
LLPS-Cas-3354Carlito syrichta97.130.01528
LLPS-Mea-4227Mesocricetus auratus97.120.0 529
LLPS-Chs-0765Chlorocebus sabaeus97.00.01533
LLPS-Bot-1716Bos taurus96.990.01523
LLPS-Caj-0210Callithrix jacchus96.870.01530
LLPS-Aon-4791Aotus nancymaae96.870.01530
LLPS-Rhb-1899Rhinopithecus bieti96.870.01529
LLPS-Myl-2710Myotis lucifugus96.740.01521
LLPS-Ran-3895Rattus norvegicus96.740.01529
LLPS-Loa-3898Loxodonta africana96.740.01521
LLPS-Orc-2362Oryctolagus cuniculus96.350.01532
LLPS-Aim-2287Ailuropoda melanoleuca95.880.01326
LLPS-Eqc-2679Equus caballus95.830.01525
LLPS-Mod-3253Monodelphis domestica95.430.01516
LLPS-Fud-0659Fukomys damarensis95.040.01504
LLPS-Mam-0205Macaca mulatta94.780.01478
LLPS-Sah-0240Sarcophilus harrisii94.020.01500
LLPS-Cap-3523Cavia porcellus93.610.01489
LLPS-Anp-2628Anas platyrhynchos93.60.01494
LLPS-Dio-3607Dipodomys ordii93.080.01452
LLPS-Gaga-1759Gallus gallus93.080.01489
LLPS-Meg-2890Meleagris gallopavo92.950.01487
LLPS-Tag-2004Taeniopygia guttata92.820.01483
LLPS-Fia-3322Ficedula albicollis92.690.01483
LLPS-Pes-3806Pelodiscus sinensis92.560.01483
LLPS-Anc-0093Anolis carolinensis92.440.01481
LLPS-Xet-2867Xenopus tropicalis91.640.01474
LLPS-Lac-2910Latimeria chalumnae89.70.01397
LLPS-Leo-2494Lepisosteus oculatus89.690.01447
LLPS-Ora-1189Ornithorhynchus anatinus89.270.0 883
LLPS-Orn-1727Oreochromis niloticus87.60.01415
LLPS-Scf-0941Scleropages formosus87.340.01411
LLPS-Gaa-0692Gasterosteus aculeatus87.080.01414
LLPS-Scm-2416Scophthalmus maximus86.950.01405
LLPS-Pof-2530Poecilia formosa86.70.01408
LLPS-Asm-0543Astyanax mexicanus86.420.01396
LLPS-Xim-2272Xiphophorus maculatus86.310.01402
LLPS-Orl-3517Oryzias latipes85.920.01392
LLPS-Dar-3965Danio rerio85.90.01394
LLPS-Icp-2240Ictalurus punctatus85.120.01382
LLPS-Tar-2862Takifugu rubripes84.460.01372
LLPS-Nol-2466Nomascus leucogenys84.330.01379
LLPS-Ten-1353Tetraodon nigroviridis84.270.01359
LLPS-Otg-3036Otolemur garnettii74.610.01117
LLPS-Drm-0633Drosophila melanogaster72.910.01189
LLPS-Cii-1917Ciona intestinalis71.040.01177
LLPS-Cis-1020Ciona savignyi69.520.01144
LLPS-Cae-0674Caenorhabditis elegans62.150.0 688
LLPS-Crn-0713Cryptococcus neoformans61.870.0 937
LLPS-Abg-0596Absidia glauca61.690.0 942
LLPS-Spr-0518Sporisorium reilianum61.330.0 955
LLPS-Usm-0891Ustilago maydis60.810.0 962
LLPS-Miv-0260Microbotryum violaceum60.50.0 942
LLPS-Pug-1180Puccinia graminis60.450.0 943
LLPS-Mel-0226Melampsora laricipopulina60.240.0 949
LLPS-Put-1187Puccinia triticina59.790.0 692
LLPS-Tum-1169Tuber melanosporum59.10.0 896
LLPS-Trr-0571Trichoderma reesei58.650.0 902
LLPS-Blg-1585Blumeria graminis58.610.0 892
LLPS-Asn-1567Aspergillus nidulans58.520.0 867
LLPS-Scs-1051Sclerotinia sclerotiorum58.50.0 893
LLPS-Gag-0180Gaeumannomyces graminis57.990.0 888
LLPS-Trv-1144Trichoderma virens57.990.0 892
LLPS-Nec-0214Neurospora crassa57.930.0 873
LLPS-Map-1129Magnaporthe poae57.860.0 889
LLPS-Fuv-0744Fusarium verticillioides57.860.0 884
LLPS-Fuo-0170Fusarium oxysporum57.860.0 885
LLPS-Asni-0312Aspergillus niger57.80.0 870
LLPS-Cog-0708Colletotrichum gloeosporioides57.780.0 874
LLPS-Ast-0880Aspergillus terreus57.710.0 862
LLPS-Cogr-0347Colletotrichum graminicola57.690.0 882
LLPS-Mao-0777Magnaporthe oryzae57.670.0 887
LLPS-Coo-1346Colletotrichum orbiculare57.60.0 880
LLPS-Beb-0530Beauveria bassiana57.60.0 890
LLPS-Asc-0204Aspergillus clavatus57.450.0 855
LLPS-Asf-0137Aspergillus flavus57.280.0 877
LLPS-Aso-0160Aspergillus oryzae57.280.0 877
LLPS-Dos-0349Dothistroma septosporum57.250.0 885
LLPS-Lem-1377Leptosphaeria maculans57.160.0 875
LLPS-Scj-0960Schizosaccharomyces japonicus57.110.0 891
LLPS-Ved-0454Verticillium dahliae57.110.0 874
LLPS-Fus-1441Fusarium solani57.070.0 874
LLPS-Scp-1052Schizosaccharomyces pombe56.860.0 871
LLPS-Pyt-0904Pyrenophora teres56.770.0 877
LLPS-Asfu-0467Aspergillus fumigatus56.560.0 850
LLPS-Nef-0258Neosartorya fischeri56.540.0 852
LLPS-Zyt-0552Zymoseptoria tritici56.410.0 873
LLPS-Pytr-0389Pyrenophora triticirepentis56.370.0 873
LLPS-Scc-0371Schizosaccharomyces cryophilus55.660.0 864
LLPS-Yal-1564Yarrowia lipolytica55.130.0 860
LLPS-Phn-0901Phaeosphaeria nodorum54.70.0 843
LLPS-Gas-0982Galdieria sulphuraria51.940.0 810
LLPS-Asg-1355Ashbya gossypii51.910.0 781
LLPS-Chc-0427Chondrus crispus51.770.0 780
LLPS-Php-0403Physcomitrella patens50.450.0 793
LLPS-Sac-0903Saccharomyces cerevisiae49.930.0 751
LLPS-Glm-2893Glycine max48.690.0 751
LLPS-Dac-0902Daucus carota48.550.0 735
LLPS-Phv-0369Phaseolus vulgaris48.510.0 750
LLPS-Amt-1074Amborella trichopoda48.450.0 756
LLPS-Sem-1791Selaginella moellendorffii48.310.0 727
LLPS-Orm-1191Oryza meridionalis48.20.0 728
LLPS-Brd-1837Brachypodium distachyon48.130.0 735
LLPS-Viv-1690Vitis vinifera48.120.0 752
LLPS-Orgl-1305Oryza glumaepatula48.070.0 727
LLPS-Orni-1531Oryza nivara48.070.0 726
LLPS-Ori-0503Oryza indica48.070.0 727
LLPS-Org-0656Oryza glaberrima48.070.0 727
LLPS-Arl-2445Arabidopsis lyrata48.040.0 745
LLPS-Cus-0442Cucumis sativus47.930.0 740
LLPS-Gor-2318Gossypium raimondii47.850.0 744
LLPS-Lep-0330Leersia perrieri47.80.0 733
LLPS-Met-0325Medicago truncatula47.780.0 746
LLPS-Tra-1231Triticum aestivum47.780.0 720
LLPS-Orb-0760Oryza barthii47.780.0 616
LLPS-Mae-1907Manihot esculenta47.670.0 756
LLPS-Sei-1688Setaria italica47.610.0 716
LLPS-Vir-0064Vigna radiata47.550.0 744
LLPS-Sob-1918Sorghum bicolor47.550.0 723
LLPS-Orbr-2166Oryza brachyantha47.540.0 712
LLPS-Brr-1465Brassica rapa47.540.0 744
LLPS-Via-1965Vigna angularis47.420.0 742
LLPS-Zem-0952Zea mays47.420.0 712
LLPS-Sot-1021Solanum tuberosum47.380.0 735
LLPS-Thc-1840Theobroma cacao47.330.0 735
LLPS-Hea-2309Helianthus annuus47.330.0 726
LLPS-Osl-0469Ostreococcus lucimarinus47.280.0 670
LLPS-Hov-0443Hordeum vulgare47.260.0 719
LLPS-Sol-0682Solanum lycopersicum47.250.0 733
LLPS-Nia-1424Nicotiana attenuata47.220.0 736
LLPS-Prp-2157Prunus persica47.20.0 746
LLPS-Coc-0447Corchorus capsularis47.20.0 726
LLPS-Bro-2408Brassica oleracea46.880.0 738
LLPS-Cym-0143Cyanidioschyzon merolae46.690.0 679
LLPS-Pot-2536Populus trichocarpa46.640.0 717
LLPS-Orp-1250Oryza punctata46.490.0 720
LLPS-Art-1901Arabidopsis thaliana46.40.0 711
LLPS-Ors-0867Oryza sativa46.240.0 697
LLPS-Brn-2119Brassica napus46.080.0 716
LLPS-Chr-1157Chlamydomonas reinhardtii45.540.0 690
LLPS-Kop-1321Komagataella pastoris45.250.0 659
LLPS-Mua-1920Musa acuminata44.940.0 658
LLPS-Orr-0018Oryza rufipogon43.670.0 662
LLPS-Tru-2010Triticum urartu43.233e-169 510