• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Nol-2466
SEC23A

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Protein transport protein SEC23
Gene Name: SEC23A
Ensembl Gene: ENSNLEG00000003954.2
Ensembl Protein: ENSNLEP00000049023.1
Organism: Nomascus leucogenys
Taxa ID: 61853
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Stress granule, Postsynaptic densityPredicted from orthologs(View)

▼ FUNCTION

Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MTTYLEFIQQ  NEERDGVRFS  WNVWPSSRLE  ATRMVVPVAA  LFTPLKERPD  LPPIQYEPVL  60
61    CSRTTCRAVL  NPLCQVDYRA  KLWACNFCYQ  RNQFPPSYAG  ISELNQPAEL  LPQFSSIEYV  120
121   VLRGPQMPLI  FLYVVDTCME  DEDLQALKES  MQMSLSLLPP  TALVGLITFG  RMVQVHELGC  180
181   EGISKSYVFR  GTKDLSAKQL  QEMLGLSKVP  VTQATRGPQV  QQPPPSNRFL  QPVQKIDMNL  240
241   TDLLGELQRD  PWPVPQGKRP  LRSSGVALSI  AVGLLECTFP  NTGARIMMFI  GGPATQGPGM  300
301   VVGDELKTPI  RSWHDIDKDN  AKYVKKGTKH  FEALANRAAT  TGHVIDIYAC  ALDQTGLLEM  360
361   KCCPNLTGGY  MVMGDSFNTS  LFKQTFQRVF  TKDMHGQFKM  GFGGTLEIKT  SREIKISGAI  420
421   GPCVSLNSKG  PCVSENEIGT  GGTCQWKICG  LSPTTTLAIY  FEVVNQHNAP  IPQGGRGAIQ  480
481   FVTQYQHSSG  QRRIRVTTIA  RNWADAQTQI  QNIAASFDQE  AAAILMARLA  IYRAETEEGP  540
541   DVLRWLDRQL  IRLCQKFGEY  HKDDPSSFRF  SETFSLYPQF  MFHLRRSSFL  QVFNNSPDES  600
601   SYYRHHFMRQ  DLTQSLIMIQ  PILYAYSFSG  PPEPVLLDSS  SILADRILLM  DTFFQILIYH  660
661   GETIAQWRKS  GYQDMPEYEN  FRHLLQAPVD  DAQEILHSRF  PMPRYIDTEH  GGSQARFLLS  720
721   KVNPSQTHNN  MYAWGQESGA  PILTDDVSLQ  VFMDHLKKLA  VSSAA  765
Nucleotide CDS Sequence (FASTA)
1     ATGACAACCT  ATTTGGAATT  CATTCAACAA  AATGAAGAAC  GAGATGGAGT  CCGATTTAGT  60
61    TGGAATGTTT  GGCCATCAAG  TCGACTGGAA  GCTACAAGAA  TGGTTGTGCC  TGTGGCAGCC  120
121   CTGTTTACAC  CACTGAAAGA  GAGACCTGAC  TTACCACCTA  TTCAATATGA  GCCTGTTCTG  180
181   TGTAGTAGGA  CCACTTGCCG  TGCAGTTTTG  AATCCTTTAT  GTCAGGTGGA  TTATCGAGCA  240
241   AAACTTTGGG  CTTGCAACTT  TTGTTACCAA  AGGAATCAGT  TTCCACCTAG  TTATGCTGGT  300
301   ATATCTGAAC  TGAATCAGCC  TGCTGAACTT  TTACCTCAGT  TTTCTAGCAT  TGAATATGTA  360
361   GTTCTGCGTG  GTCCTCAGAT  GCCTTTGATA  TTCCTCTATG  TGGTTGATAC  TTGCATGGAA  420
421   GATGAAGATT  TACAAGCCCT  GAAAGAATCC  ATGCAGATGT  CATTAAGTCT  TTTACCACCT  480
481   ACAGCTTTGG  TTGGACTTAT  TACTTTTGGG  AGAATGGTTC  AGGTTCATGA  ACTTGGATGT  540
541   GAAGGCATTT  CAAAAAGCTA  TGTCTTCAGA  GGAACAAAAG  ATTTGTCTGC  CAAACAACTG  600
601   CAGGAAATGC  TGGGGCTCTC  TAAAGTACCA  GTTACTCAAG  CAACACGTGG  TCCTCAGGTA  660
661   CAGCAGCCAC  CTCCTTCCAA  CAGATTCTTA  CAGCCAGTAC  AGAAAATAGA  CATGAATCTC  720
721   ACAGATCTTC  TGGGAGAACT  CCAGCGAGAC  CCTTGGCCTG  TACCACAGGG  AAAGAGACCT  780
781   TTGCGTTCCT  CCGGAGTGGC  ACTTTCCATA  GCTGTAGGAC  TGCTGGAGTG  TACTTTTCCC  840
841   AACACTGGTG  CTCGTATCAT  GATGTTCATT  GGCGGTCCTG  CTACTCAGGG  GCCTGGAATG  900
901   GTGGTCGGAG  ATGAGTTGAA  GACACCTATA  AGATCGTGGC  ATGACATTGA  CAAAGACAAT  960
961   GCCAAATATG  TTAAAAAGGG  AACTAAGCAT  TTTGAAGCAT  TGGCTAATCG  AGCTGCTACA  1020
1021  ACTGGCCATG  TTATTGATAT  CTATGCATGT  GCATTAGATC  AGACAGGTCT  CCTGGAGATG  1080
1081  AAGTGCTGTC  CCAACCTTAC  TGGAGGATAC  ATGGTAATGG  GTGATTCTTT  CAATACGTCC  1140
1141  TTATTCAAAC  AAACTTTTCA  AAGAGTCTTT  ACCAAAGACA  TGCATGGACA  GTTTAAAATG  1200
1201  GGCTTTGGTG  GTACACTAGA  AATAAAGACC  TCAAGGGAAA  TAAAGATTTC  AGGAGCTATT  1260
1261  GGACCCTGTG  TGTCACTCAA  TTCTAAAGGA  CCCTGTGTGT  CTGAAAATGA  GATAGGAACA  1320
1321  GGTGGCACAT  GTCAGTGGAA  GATATGTGGA  CTTAGTCCCA  CTACAACCTT  AGCCATATAT  1380
1381  TTTGAGGTTG  TCAATCAGCA  TAATGCTCCA  ATTCCTCAAG  GAGGGCGTGG  TGCAATCCAG  1440
1441  TTTGTGACTC  AGTATCAGCA  TTCAAGTGGG  CAGAGACGCA  TCCGAGTGAC  CACCATTGCT  1500
1501  AGGAACTGGG  CAGATGCTCA  AACTCAAATC  CAAAACATTG  CTGCATCTTT  TGACCAGGAG  1560
1561  GCAGCTGCCA  TTCTTATGGC  CCGGCTAGCA  ATATATAGAG  CAGAAACAGA  AGAAGGTCCA  1620
1621  GATGTCCTTA  GGTGGCTGGA  CAGACAGCTC  ATTCGACTGT  GTCAGAAATT  TGGAGAATAT  1680
1681  CATAAAGATG  ACCCAAGTTC  CTTCAGATTT  TCAGAAACTT  TCTCCCTTTA  TCCACAGTTT  1740
1741  ATGTTTCATT  TAAGAAGATC  TTCTTTCCTG  CAAGTTTTTA  ATAATAGTCC  TGATGAGAGT  1800
1801  TCATATTATC  GTCACCATTT  TATGCGTCAA  GATCTGACTC  AGTCTCTAAT  TATGATTCAG  1860
1861  CCTATCCTGT  ATGCATATTC  TTTTAGTGGA  CCACCAGAGC  CGGTTCTTCT  TGATAGCAGT  1920
1921  AGCATTCTTG  CAGATCGTAT  TCTTCTCATG  GACACATTCT  TCCAGATTTT  GATTTATCAT  1980
1981  GGTGAGACCA  TAGCACAGTG  GCGGAAGTCA  GGATACCAGG  ACATGCCTGA  ATATGAAAAT  2040
2041  TTCCGCCACC  TTCTGCAAGC  CCCAGTGGAT  GATGCACAGG  AAATTCTTCA  CTCCAGATTT  2100
2101  CCAATGCCAA  GATACATTGA  CACTGAACAT  GGAGGCAGCC  AGGCCCGTTT  CCTCCTTTCA  2160
2161  AAAGTCAACC  CTTCACAGAC  TCATAATAAT  ATGTATGCCT  GGGGGCAGGA  GTCTGGAGCA  2220
2221  CCTATTCTTA  CAGATGATGT  TAGTTTACAA  GTATTTATGG  ATCACTTGAA  GAAACTTGCT  2280
2281  GTGTCCAGTG  CTGCTTGA  2298

▼ KEYWORD

ID
Family
Complete proteome
Cytoplasm
Cytoplasmic vesicle
Endoplasmic reticulum
ER-Golgi transport
Membrane
Metal-binding
Protein transport
Reference proteome
Transport
Zinc

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
COPII vesicle coat
Cellular Component
Cytosol
Cellular Component
Endoplasmic reticulum exit site
Cellular Component
Endoplasmic reticulum membrane
Cellular Component
Extrinsic component of membrane
Cellular Component
Golgi membrane
Cellular Component
Perinuclear region of cytoplasm
Molecular Function
Zinc ion binding
Biological Process
COPII-coated vesicle cargo loading
Biological Process
Intracellular protein transport
Biological Process
Protein localization to plasma membrane

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Mam-1823Macaca mulatta100.00.01600
LLPS-Man-0104Macaca nemestrina100.00.01600
LLPS-Pat-1655Pan troglodytes100.00.01600
LLPS-Paa-1471Papio anubis100.00.01600
LLPS-Gog-0336Gorilla gorilla100.00.01600
LLPS-Cea-2834Cercocebus atys100.00.01600
LLPS-Maf-0238Macaca fascicularis100.00.01600
LLPS-Chs-2719Chlorocebus sabaeus100.00.01600
LLPS-Rhb-2973Rhinopithecus bieti99.870.01597
LLPS-Hos-2178Homo sapiens99.870.01599
LLPS-Pap-3948Pan paniscus99.870.01597
LLPS-Ict-3860Ictidomys tridecemlineatus99.610.01595
LLPS-Cas-2068Carlito syrichta99.610.01595
LLPS-Urm-0831Ursus maritimus99.610.01595
LLPS-Fec-1110Felis catus99.610.01595
LLPS-Aim-1319Ailuropoda melanoleuca99.610.01595
LLPS-Mup-3601Mustela putorius furo99.610.01595
LLPS-Bot-2032Bos taurus99.610.01595
LLPS-Sus-2055Sus scrofa99.610.01595
LLPS-Caj-2266Callithrix jacchus99.590.01538
LLPS-Cap-4047Cavia porcellus99.480.01592
LLPS-Orc-1320Oryctolagus cuniculus99.480.01595
LLPS-Aon-2054Aotus nancymaae99.480.01590
LLPS-Eqc-4558Equus caballus99.460.01532
LLPS-Loa-1975Loxodonta africana99.350.01592
LLPS-Dio-2314Dipodomys ordii99.220.01591
LLPS-Caf-2075Canis familiaris99.210.01578
LLPS-Ova-0123Ovis aries99.080.01578
LLPS-Ran-2702Rattus norvegicus99.080.01589
LLPS-Mum-3101Mus musculus99.080.01589
LLPS-Myl-2986Myotis lucifugus98.70.01579
LLPS-Fud-2892Fukomys damarensis98.690.01583
LLPS-Mod-2165Monodelphis domestica98.040.01577
LLPS-Mal-4026Mandrillus leucophaeus97.520.01545
LLPS-Ora-0947Ornithorhynchus anatinus97.520.01571
LLPS-Tag-0181Taeniopygia guttata96.730.01559
LLPS-Fia-2770Ficedula albicollis96.60.01558
LLPS-Anp-1138Anas platyrhynchos96.470.01558
LLPS-Gaga-2033Gallus gallus96.340.01556
LLPS-Meg-1594Meleagris gallopavo96.180.01544
LLPS-Pes-1686Pelodiscus sinensis96.170.01536
LLPS-Anc-2060Anolis carolinensis96.080.01545
LLPS-Sah-2139Sarcophilus harrisii94.770.01513
LLPS-Lac-1974Latimeria chalumnae94.120.01525
LLPS-Poa-4131Pongo abelii93.20.01469
LLPS-Xet-2485Xenopus tropicalis92.970.01502
LLPS-Asm-0579Astyanax mexicanus92.550.01499
LLPS-Leo-3582Lepisosteus oculatus92.30.01495
LLPS-Icp-2240Ictalurus punctatus91.90.01477
LLPS-Scf-0903Scleropages formosus91.630.01491
LLPS-Dar-2463Danio rerio90.980.01476
LLPS-Orn-1829Oreochromis niloticus90.20.01467
LLPS-Pof-2803Poecilia formosa89.950.01464
LLPS-Gaa-0762Gasterosteus aculeatus89.950.01460
LLPS-Xim-2105Xiphophorus maculatus89.930.01468
LLPS-Tar-1498Takifugu rubripes89.930.01465
LLPS-Mea-1361Mesocricetus auratus87.470.01333
LLPS-Ten-1788Tetraodon nigroviridis87.390.01390
LLPS-Scm-1679Scophthalmus maximus86.930.01405
LLPS-Otg-4066Otolemur garnettii83.640.01302
LLPS-Orl-3517Oryzias latipes81.620.01342
LLPS-Drm-0633Drosophila melanogaster73.180.01221
LLPS-Cii-1917Ciona intestinalis73.040.01202
LLPS-Cis-1020Ciona savignyi71.90.01178
LLPS-Abg-0878Absidia glauca61.240.0 971
LLPS-Spr-0518Sporisorium reilianum60.730.0 967
LLPS-Usm-0891Ustilago maydis60.60.0 978
LLPS-Pug-1180Puccinia graminis60.210.0 953
LLPS-Crn-0713Cryptococcus neoformans60.160.0 949
LLPS-Miv-0260Microbotryum violaceum59.90.0 952
LLPS-Mel-0226Melampsora laricipopulina59.840.0 957
LLPS-Put-1187Puccinia triticina59.750.0 709
LLPS-Tum-1169Tuber melanosporum59.230.0 917
LLPS-Mao-0777Magnaporthe oryzae58.120.0 900
LLPS-Blg-1585Blumeria graminis57.950.0 901
LLPS-Trr-0571Trichoderma reesei57.920.0 897
LLPS-Fuo-0170Fusarium oxysporum57.780.0 891
LLPS-Fuv-0744Fusarium verticillioides57.780.0 891
LLPS-Scs-1051Sclerotinia sclerotiorum57.710.0 895
LLPS-Asc-0204Aspergillus clavatus57.710.0 871
LLPS-Beb-0530Beauveria bassiana57.610.0 894
LLPS-Map-1129Magnaporthe poae57.60.0 897
LLPS-Cogr-0347Colletotrichum graminicola57.560.0 891
LLPS-Nec-0214Neurospora crassa57.50.0 880
LLPS-Asn-1567Aspergillus nidulans57.50.0 878
LLPS-Coo-1346Colletotrichum orbiculare57.480.0 889
LLPS-Cog-0708Colletotrichum gloeosporioides57.350.0 880
LLPS-Gag-0180Gaeumannomyces graminis57.330.0 894
LLPS-Ved-0454Verticillium dahliae57.070.0 882
LLPS-Trv-1144Trichoderma virens56.940.0 888
LLPS-Fus-1441Fusarium solani56.730.0 877
LLPS-Nef-0258Neosartorya fischeri56.710.0 868
LLPS-Pytr-0389Pyrenophora triticirepentis56.680.0 891
LLPS-Pyt-0904Pyrenophora teres56.680.0 894
LLPS-Asfu-0467Aspergillus fumigatus56.60.0 865
LLPS-Ast-0880Aspergillus terreus56.60.0 871
LLPS-Asf-0137Aspergillus flavus56.430.0 886
LLPS-Scj-0960Schizosaccharomyces japonicus56.430.0 897
LLPS-Aso-0160Aspergillus oryzae56.430.0 886
LLPS-Asni-0312Aspergillus niger56.430.0 881
LLPS-Dos-0349Dothistroma septosporum56.380.0 886
LLPS-Scp-1052Schizosaccharomyces pombe56.320.0 876
LLPS-Zyt-0552Zymoseptoria tritici56.060.0 880
LLPS-Cae-0674Caenorhabditis elegans55.840.0 943
LLPS-Lem-1377Leptosphaeria maculans55.790.0 872
LLPS-Scc-0371Schizosaccharomyces cryophilus55.190.0 873
LLPS-Yal-1564Yarrowia lipolytica55.060.0 870
LLPS-Phn-0901Phaeosphaeria nodorum54.360.0 857
LLPS-Gas-0982Galdieria sulphuraria52.20.0 840
LLPS-Asg-1355Ashbya gossypii51.580.0 789
LLPS-Chc-0427Chondrus crispus51.50.0 793
LLPS-Php-0403Physcomitrella patens50.970.0 804
LLPS-Phv-0369Phaseolus vulgaris49.930.0 779
LLPS-Orb-0760Oryza barthii49.770.0 649
LLPS-Sac-0903Saccharomyces cerevisiae49.680.0 767
LLPS-Glm-2893Glycine max49.480.0 769
LLPS-Cus-0442Cucumis sativus49.420.0 766
LLPS-Viv-1690Vitis vinifera49.280.0 783
LLPS-Vir-0064Vigna radiata49.160.0 774
LLPS-Gor-2318Gossypium raimondii49.090.0 775
LLPS-Lep-0330Leersia perrieri49.090.0 761
LLPS-Prp-2157Prunus persica49.020.0 776
LLPS-Met-0325Medicago truncatula48.960.0 775
LLPS-Brd-1837Brachypodium distachyon48.90.0 760
LLPS-Sem-1791Selaginella moellendorffii48.880.0 746
LLPS-Via-1965Vigna angularis48.840.0 773
LLPS-Amt-1074Amborella trichopoda48.830.0 769
LLPS-Bro-2354Brassica oleracea48.770.0 764
LLPS-Sei-1688Setaria italica48.770.0 744
LLPS-Orm-1191Oryza meridionalis48.710.0 753
LLPS-Brr-1465Brassica rapa48.70.0 769
LLPS-Hov-0443Hordeum vulgare48.690.0 749
LLPS-Dac-0902Daucus carota48.680.0 748
LLPS-Thc-1840Theobroma cacao48.630.0 770
LLPS-Hea-2309Helianthus annuus48.510.0 744
LLPS-Org-0656Oryza glaberrima48.460.0 753
LLPS-Orgl-1305Oryza glumaepatula48.460.0 753
LLPS-Orni-1531Oryza nivara48.460.0 751
LLPS-Ori-0503Oryza indica48.460.0 753
LLPS-Mae-1907Manihot esculenta48.450.0 778
LLPS-Tra-1231Triticum aestivum48.430.0 748
LLPS-Sot-1021Solanum tuberosum48.40.0 757
LLPS-Nia-1424Nicotiana attenuata48.370.0 763
LLPS-Sob-1918Sorghum bicolor48.320.0 748
LLPS-Sol-0682Solanum lycopersicum48.270.0 760
LLPS-Zem-0952Zea mays48.190.0 741
LLPS-Arl-2445Arabidopsis lyrata48.030.0 756
LLPS-Coc-0447Corchorus capsularis47.930.0 751
LLPS-Brn-2119Brassica napus47.720.0 745
LLPS-Pot-2536Populus trichocarpa47.610.0 741
LLPS-Orbr-2166Oryza brachyantha47.60.0 722
LLPS-Osl-0234Ostreococcus lucimarinus47.530.0 735
LLPS-Orp-1250Oryza punctata47.140.0 746
LLPS-Art-0405Arabidopsis thaliana46.920.0 746
LLPS-Mua-1920Musa acuminata46.880.0 697
LLPS-Ors-0867Oryza sativa46.560.0 710
LLPS-Cym-0143Cyanidioschyzon merolae45.980.0 692
LLPS-Chr-1157Chlamydomonas reinhardtii45.080.0 701
LLPS-Kop-1321Komagataella pastoris44.910.0 667
LLPS-Tru-2010Triticum urartu44.442e-176 528
LLPS-Orr-0018Oryza rufipogon44.30.0 684