• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Poa-3291
SEC23B

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Protein transport protein SEC23
Gene Name: SEC23B, CR201_G0019762
Ensembl Gene: ENSPPYG00000010739.2
Ensembl Protein: ENSPPYP00000012004.2
Organism: Pongo abelii
Taxa ID: 9601
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MATYLEFIQQ  NEERDGVRFS  WNVWPSSRLE  ATRMVVPLAC  LLTPLKERPD  LPPVQYEPVL  60
61    CSRPTCKAVL  NPLCQVDYRA  KLWACNFCFQ  RNQFPPAYGG  ISEVNQPAEL  MPQFSTIEYV  120
121   IQRGAQSPLI  FLYVVDTCLE  EDDLQALKES  LQMSLSLLPP  DALVGLITFG  RMVQVHELSC  180
181   EGISKSYVFR  GTKDLTAKQI  QDMLGLTKPA  MPMQQARPAQ  PQEHPFASSR  FLQPVHKIDM  240
241   NLTDLLGELQ  RDPWPVTQGK  RPLRSTGVAL  SIAVGLLEGT  FPNTGARIML  FTGGPPTQGP  300
301   GMVVGDELKI  PIRSWHDIEK  DNARFMKKAT  KHYEMLANRT  AANGHCIDIY  ACALDQTGLL  360
361   EMKCCANLTG  GYMVMGDSFN  TSLFKQTFQR  IFTKDFNGDF  RMAFGATLDV  KTSRELKIAG  420
421   AIGPCVSLNV  KGPCVSENEL  GVGGTSQWKI  CGLDPTSTLG  IYFEVVNQHN  TPIPQGGRGA  480
481   IQFVTHYQHS  STQRRIRVTT  IARNWADVQS  QLRHIEAAFD  QEAAAVLMAR  LGVFRAESEE  540
541   GPDVLRWLDR  QLIRLCQKFG  QYNKEDPTSF  RLSDSFSLYP  QFMFHLRRSP  FLQVFNNSPD  600
601   ESSYYRHHFA  RQDLTQSLIM  IQPILYSYSF  HGPPEPVLLD  SSSILADRIL  LMDTFFQIVI  660
661   YLGETIAQWR  KAGYQDMPEY  ENFKHLLQAP  LDDAQEILQA  RFPMPRYINT  EHGGSQARFL  720
721   LSKVNPSQTH  NNLYAWGQET  GAPILTDDVS  LQVFMDHLKK  LAVSSAC  767
Nucleotide CDS Sequence (FASTA)
1     ATGGCGACAT  ACCTGGAGTT  CATCCAGCAG  AATGAAGAAC  GGGATGGTGT  GCGTTTTAGT  60
61    TGGAACGTGT  GGCCTTCCAG  CCGGCTGGAG  GCTACAAGAA  TGGTTGTACC  CCTGGCTTGT  120
121   CTCCTTACTC  CTTTGAAAGA  ACGTCCAGAC  CTACCTCCTG  TACAATATGA  ACCTGTGCTT  180
181   TGCAGCAGGC  CAACTTGTAA  AGCTGTTCTC  AACCCACTTT  GTCAGGTTGA  TTATCGAGCA  240
241   AAACTTTGGG  CCTGTAATTT  CTGTTTTCAA  AGAAATCAGT  TTCCTCCAGC  TTATGGAGGC  300
301   ATATCTGAGG  TGAATCAGCC  TGCCGAATTG  ATGCCCCAAT  TTTCTACAAT  TGAGTACGTG  360
361   ATACAGCGAG  GTGCTCAGTC  CCCTCTGATC  TTTCTCTATG  TGGTTGACAC  ATGCCTGGAG  420
421   GAAGATGACC  TTCAAGCGCT  CAAAGAGTCC  CTGCAGATGT  CCCTGAGTCT  TCTTCCTCCA  480
481   GATGCTCTGG  TGGGTCTGAT  CACATTTGGA  AGGATGGTGC  AGGTTCATGA  GCTAAGCTGT  540
541   GAAGGAATCT  CCAAAAGTTA  TGTCTTCCGA  GGGACCAAGG  ATTTAACTGC  AAAGCAAATA  600
601   CAGGATATGT  TGGGCCTGAC  CAAGCCAGCC  ATGCCCATGC  AGCAAGCACG  ACCTGCGCAA  660
661   CCACAGGAGC  ACCCTTTTGC  TTCAAGCAGA  TTTCTGCAGC  CTGTTCACAA  GATTGATATG  720
721   AACCTCACTG  ATCTTCTTGG  GGAGCTACAG  AGGGACCCAT  GGCCAGTAAC  TCAGGGGAAG  780
781   AGACCTTTGC  GATCCACTGG  TGTGGCTTTG  TCCATTGCTG  TTGGCTTGCT  GGAGGGCACT  840
841   TTTCCAAACA  CGGGAGCCAG  GATCATGCTG  TTTACTGGAG  GGCCCCCTAC  CCAAGGGCCT  900
901   GGCATGGTGG  TTGGAGATGA  ATTAAAGATT  CCTATTCGTT  CTTGGCATGA  TATTGAGAAA  960
961   GATAATGCAC  GATTCATGAA  AAAGGCAACC  AAGCACTATG  AGATGCTTGC  TAATCGAACA  1020
1021  GCTGCAAATG  GTCACTGCAT  TGATATTTAT  GCTTGTGCCC  TTGATCAAAC  TGGACTTCTG  1080
1081  GAGATGAAGT  GTTGTGCAAA  TCTCACTGGA  GGCTACATGG  TAATGGGAGA  TTCTTTCAAC  1140
1141  ACTTCTCTCT  TCAAGCAGAC  ATTCCAAAGA  ATCTTTACTA  AAGATTTTAA  TGGAGATTTC  1200
1201  CGAATGGCAT  TTGGTGCTAC  TTTGGACGTA  AAGACCTCTC  GGGAACTGAA  GATTGCAGGA  1260
1261  GCCATTGGTC  CATGCGTATC  TCTGAATGTG  AAAGGACCGT  GTGTGTCAGA  AAATGAGCTT  1320
1321  GGTGTTGGTG  GCACGAGTCA  GTGGAAAATC  TGTGGCCTAG  ATCCTACATC  TACACTTGGC  1380
1381  ATCTATTTTG  AAGTTGTCAA  TCAGCATAAC  ACCCCGATCC  CCCAAGGAGG  CAGAGGAGCC  1440
1441  ATCCAGTTTG  TCACGCATTA  TCAGCACTCC  AGCACCCAGA  GACGCATCCG  CGTGACCACC  1500
1501  ATCGCCCGAA  ATTGGGCAGA  TGTACAGAGT  CAGCTCAGGC  ACATAGAAGC  AGCATTTGAC  1560
1561  CAGGAGGCTG  CGGCAGTCTT  GATGGCACGG  CTTGGGGTGT  TCCGAGCGGA  GTCGGAGGAG  1620
1621  GGGCCTGATG  TGCTCCGGTG  GCTGGACCGA  CAACTCATCC  GACTGTGTCA  AAAGTTTGGA  1680
1681  CAGTATAACA  AAGAAGACCC  CACTTCTTTT  AGGTTATCAG  ATTCCTTTTC  TCTATATCCT  1740
1741  CAGTTCATGT  TCCATCTGAG  AAGATCTCCA  TTTCTTCAAG  TGTTTAACAA  CAGTCCTGAC  1800
1801  GAGTCGTCAT  ATTACAGACA  TCATTTTGCC  CGGCAGGACC  TGACCCAGTC  CCTCATCATG  1860
1861  ATCCAGCCCA  TTCTCTACTC  TTACTCCTTT  CATGGGCCAC  CAGAGCCAGT  ACTCTTGGAT  1920
1921  AGCAGCAGCA  TTCTAGCTGA  CAGAATTTTG  CTGATGGATA  CTTTCTTTCA  AATTGTCATT  1980
1981  TATCTTGGTG  AGACCATAGC  CCAGTGGCGT  AAAGCTGGCT  ACCAGGACAT  GCCCGAGTAT  2040
2041  GAAAACTTCA  AGCACCTTCT  GCAAGCACCA  CTGGATGATG  CTCAAGAAAT  TCTGCAAGCG  2100
2101  CGCTTCCCGA  TGCCACGTTA  CATTAACACG  GAACATGGAG  GCAGTCAGGC  TCGATTCCTT  2160
2161  TTGTCCAAAG  TGAACCCATC  TCAGACACAC  AATAACCTCT  ATGCTTGGGG  ACAGGAAACG  2220
2221  GGAGCACCCA  TCCTAACTGA  TGATGTTAGC  CTGCAGGTGT  TCATGGACCA  TTTGAAGAAG  2280
2281  CTGGCTGTCT  CCAGTGCCTG  TTAA  2304

▼ KEYWORD

ID
Family
Complete proteome
Cytoplasm
Cytoplasmic vesicle
Endoplasmic reticulum
ER-Golgi transport
Membrane
Metal-binding
Protein transport
Reference proteome
Transport
Zinc

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
COPII vesicle coat
Cellular Component
Cytosol
Cellular Component
Endoplasmic reticulum membrane
Cellular Component
Golgi membrane
Cellular Component
Perinuclear region of cytoplasm
Molecular Function
Zinc ion binding
Biological Process
COPII-coated vesicle budding
Biological Process
Intracellular protein transport

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Hos-1741Homo sapiens100.00.01569
LLPS-Gog-3796Gorilla gorilla100.00.01569
LLPS-Pat-2689Pan troglodytes99.740.01568
LLPS-Pap-4178Pan paniscus99.740.01568
LLPS-Man-3909Macaca nemestrina99.480.01565
LLPS-Maf-3127Macaca fascicularis99.480.01565
LLPS-Mal-1565Mandrillus leucophaeus99.480.01565
LLPS-Paa-4444Papio anubis99.480.01565
LLPS-Cea-4230Cercocebus atys99.350.01564
LLPS-Chs-0765Chlorocebus sabaeus99.220.01560
LLPS-Rhb-1899Rhinopithecus bieti99.090.01557
LLPS-Aon-4791Aotus nancymaae98.70.01552
LLPS-Caj-0210Callithrix jacchus98.70.01550
LLPS-Ict-4276Ictidomys tridecemlineatus98.040.01544
LLPS-Fec-3847Felis catus97.910.01547
LLPS-Cas-3354Carlito syrichta97.910.01537
LLPS-Mea-4227Mesocricetus auratus97.840.0 535
LLPS-Urm-1170Ursus maritimus97.780.01542
LLPS-Caf-2412Canis familiaris97.650.01547
LLPS-Mup-3414Mustela putorius furo97.650.01542
LLPS-Sus-3723Sus scrofa97.520.01542
LLPS-Mum-4028Mus musculus97.260.01536
LLPS-Myl-2710Myotis lucifugus97.130.01529
LLPS-Ova-0210Ovis aries97.00.01534
LLPS-Mam-0205Macaca mulatta96.870.01505
LLPS-Ran-3895Rattus norvegicus96.870.01531
LLPS-Loa-3898Loxodonta africana96.740.01516
LLPS-Bot-1716Bos taurus96.730.01525
LLPS-Orc-2362Oryctolagus cuniculus96.610.01531
LLPS-Aim-2287Ailuropoda melanoleuca95.880.01330
LLPS-Eqc-2679Equus caballus95.70.01528
LLPS-Mod-3253Monodelphis domestica95.560.01519
LLPS-Fud-0659Fukomys damarensis95.170.01506
LLPS-Sah-0240Sarcophilus harrisii94.150.01502
LLPS-Dio-3607Dipodomys ordii93.860.01460
LLPS-Anp-2628Anas platyrhynchos93.730.01495
LLPS-Cap-3523Cavia porcellus93.610.01487
LLPS-Gaga-1759Gallus gallus93.210.01491
LLPS-Meg-2890Meleagris gallopavo93.080.01488
LLPS-Fia-3322Ficedula albicollis92.820.01485
LLPS-Tag-2004Taeniopygia guttata92.820.01484
LLPS-Pes-3806Pelodiscus sinensis92.30.01482
LLPS-Xet-2867Xenopus tropicalis92.30.01479
LLPS-Anc-0093Anolis carolinensis92.050.01476
LLPS-Leo-2494Lepisosteus oculatus89.820.01444
LLPS-Lac-2910Latimeria chalumnae89.70.01395
LLPS-Ora-1189Ornithorhynchus anatinus89.480.0 882
LLPS-Orn-1727Oreochromis niloticus87.340.01411
LLPS-Scf-0941Scleropages formosus87.080.01409
LLPS-Gaa-0692Gasterosteus aculeatus86.810.01410
LLPS-Pof-2530Poecilia formosa86.70.01405
LLPS-Scm-2416Scophthalmus maximus86.680.01403
LLPS-Asm-0543Astyanax mexicanus86.680.01395
LLPS-Xim-2272Xiphophorus maculatus86.310.01400
LLPS-Orl-3517Oryzias latipes86.050.01389
LLPS-Dar-2463Danio rerio85.770.01383
LLPS-Icp-2240Ictalurus punctatus84.990.01378
LLPS-Nol-2466Nomascus leucogenys84.460.01383
LLPS-Tar-2862Takifugu rubripes84.460.01365
LLPS-Ten-1353Tetraodon nigroviridis84.270.01352
LLPS-Otg-3036Otolemur garnettii74.610.01114
LLPS-Drm-0633Drosophila melanogaster72.910.01186
LLPS-Cii-1917Ciona intestinalis71.560.01179
LLPS-Cis-1020Ciona savignyi70.330.01146
LLPS-Crn-0713Cryptococcus neoformans62.010.0 941
LLPS-Cae-0674Caenorhabditis elegans61.960.0 684
LLPS-Spr-0518Sporisorium reilianum61.850.0 956
LLPS-Abg-0596Absidia glauca61.560.0 942
LLPS-Usm-0891Ustilago maydis61.330.0 964
LLPS-Miv-0260Microbotryum violaceum60.770.0 947
LLPS-Pug-1180Puccinia graminis60.580.0 950
LLPS-Mel-0226Melampsora laricipopulina60.370.0 952
LLPS-Put-1187Puccinia triticina59.960.0 699
LLPS-Tum-1169Tuber melanosporum59.630.0 896
LLPS-Blg-1585Blumeria graminis59.030.0 890
LLPS-Asn-1567Aspergillus nidulans58.650.0 869
LLPS-Scs-1051Sclerotinia sclerotiorum58.630.0 888
LLPS-Trr-0571Trichoderma reesei58.520.0 895
LLPS-Nec-0214Neurospora crassa58.060.0 872
LLPS-Coo-1346Colletotrichum orbiculare57.990.0 877
LLPS-Cog-0708Colletotrichum gloeosporioides57.920.0 870
LLPS-Asc-0204Aspergillus clavatus57.90.0 849
LLPS-Trv-1144Trichoderma virens57.860.0 883
LLPS-Cogr-0347Colletotrichum graminicola57.820.0 880
LLPS-Asni-0312Aspergillus niger57.80.0 867
LLPS-Fuo-0170Fusarium oxysporum57.730.0 879
LLPS-Fuv-0744Fusarium verticillioides57.730.0 878
LLPS-Gag-0180Gaeumannomyces graminis57.730.0 880
LLPS-Mao-0777Magnaporthe oryzae57.670.0 880
LLPS-Beb-0530Beauveria bassiana57.60.0 884
LLPS-Map-1129Magnaporthe poae57.60.0 880
LLPS-Ast-0880Aspergillus terreus57.580.0 858
LLPS-Lem-1377Leptosphaeria maculans57.560.0 872
LLPS-Aso-0160Aspergillus oryzae57.330.0 872
LLPS-Asf-0137Aspergillus flavus57.330.0 872
LLPS-Asfu-0467Aspergillus fumigatus57.280.0 846
LLPS-Nef-0258Neosartorya fischeri57.260.0 848
LLPS-Scp-1052Schizosaccharomyces pombe57.260.0 872
LLPS-Dos-0349Dothistroma septosporum57.250.0 878
LLPS-Fus-1441Fusarium solani57.20.0 871
LLPS-Pyt-0904Pyrenophora teres57.160.0 874
LLPS-Ved-0454Verticillium dahliae56.970.0 867
LLPS-Scj-0960Schizosaccharomyces japonicus56.970.0 888
LLPS-Pytr-0389Pyrenophora triticirepentis56.690.0 870
LLPS-Zyt-0552Zymoseptoria tritici56.540.0 869
LLPS-Yal-1564Yarrowia lipolytica55.570.0 867
LLPS-Scc-0371Schizosaccharomyces cryophilus55.530.0 861
LLPS-Phn-0901Phaeosphaeria nodorum54.950.0 845
LLPS-Gas-0982Galdieria sulphuraria52.20.0 812
LLPS-Asg-1355Ashbya gossypii51.910.0 786
LLPS-Chc-0427Chondrus crispus51.510.0 775
LLPS-Php-0403Physcomitrella patens50.450.0 790
LLPS-Sac-0903Saccharomyces cerevisiae49.930.0 755
LLPS-Glm-2893Glycine max48.820.0 750
LLPS-Amt-1074Amborella trichopoda48.70.0 754
LLPS-Brd-1837Brachypodium distachyon48.650.0 735
LLPS-Lep-0330Leersia perrieri48.580.0 734
LLPS-Phv-0369Phaseolus vulgaris48.510.0 751
LLPS-Viv-1690Vitis vinifera48.440.0 751
LLPS-Dac-0902Daucus carota48.420.0 731
LLPS-Orm-1191Oryza meridionalis48.320.0 726
LLPS-Org-0656Oryza glaberrima48.20.0 726
LLPS-Ori-0503Oryza indica48.20.0 726
LLPS-Orni-1531Oryza nivara48.20.0 724
LLPS-Orgl-1305Oryza glumaepatula48.20.0 726
LLPS-Sem-1791Selaginella moellendorffii48.180.0 723
LLPS-Orb-0760Oryza barthii48.080.0 618
LLPS-Arl-2445Arabidopsis lyrata48.040.0 745
LLPS-Sei-1688Setaria italica47.990.0 714
LLPS-Met-0325Medicago truncatula47.910.0 746
LLPS-Tra-1231Triticum aestivum47.850.0 721
LLPS-Sob-1918Sorghum bicolor47.810.0 720
LLPS-Osl-0469Ostreococcus lucimarinus47.80.0 671
LLPS-Vir-0064Vigna radiata47.80.0 744
LLPS-Orbr-2166Oryza brachyantha47.670.0 711
LLPS-Via-1965Vigna angularis47.670.0 743
LLPS-Gor-2318Gossypium raimondii47.660.0 739
LLPS-Hov-0443Hordeum vulgare47.650.0 721
LLPS-Cus-0442Cucumis sativus47.480.0 739
LLPS-Zem-0952Zea mays47.420.0 711
LLPS-Brr-1465Brassica rapa47.410.0 743
LLPS-Hea-2309Helianthus annuus47.330.0 724
LLPS-Mae-1907Manihot esculenta47.280.0 751
LLPS-Sol-0682Solanum lycopersicum47.250.0 730
LLPS-Sot-1021Solanum tuberosum47.250.0 731
LLPS-Nia-1424Nicotiana attenuata47.220.0 731
LLPS-Coc-0447Corchorus capsularis47.20.0 725
LLPS-Prp-2157Prunus persica47.20.0 744
LLPS-Cym-0143Cyanidioschyzon merolae46.820.0 677
LLPS-Orp-1250Oryza punctata46.750.0 721
LLPS-Bro-2408Brassica oleracea46.750.0 736
LLPS-Thc-1840Theobroma cacao46.750.0 732
LLPS-Ors-0867Oryza sativa46.50.0 696
LLPS-Mua-1920Musa acuminata46.430.0 679
LLPS-Pot-2536Populus trichocarpa46.380.0 714
LLPS-Art-1901Arabidopsis thaliana46.20.0 711
LLPS-Brn-2119Brassica napus46.080.0 714
LLPS-Chr-1157Chlamydomonas reinhardtii45.540.0 685
LLPS-Kop-1321Komagataella pastoris45.120.0 654
LLPS-Orr-0018Oryza rufipogon43.80.0 661
LLPS-Tru-2010Triticum urartu43.531e-170 513