• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Man-3909
SEC23B

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Protein transport protein SEC23
Gene Name: SEC23B
Ensembl Gene: ENSMNEG00000030931.1
Ensembl Protein: ENSMNEP00000013354.1
Organism: Macaca nemestrina
Taxa ID: 9545
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MATYLEFIQQ  NEERDGVRFS  WNVWPSSRLE  ATRMVVPLAC  LLTPLKERPD  LPPVQYEPVL  60
61    CSRPTCKAVL  NPLCQVDYRA  KLWACNFCFQ  RNQFPPAYGG  ISEVNQPAEL  MPQFSTIEYM  120
121   IQRGAQSPLI  FLYVVDTCLE  EDDLQALKES  LQMSLSLLPP  DALVGLITFG  RMVQVHELSC  180
181   EGISKSYVFR  GTKDLTAKQI  QDMLGLTKPA  MPMQQARPVQ  PQEHPFASTR  FLQPVHKIDM  240
241   NLTDLLGELQ  RDPWPVTQGK  RPLRSTGVAL  SIAVGLLEGT  FPNTGARIML  FTGGPPTQGP  300
301   GMVVGDELKI  PIRSWHDIEK  DNARFMKKAT  KHYEMLANRT  AANGHCIDIY  ACALDQTGLL  360
361   EMKCCANLTG  GYMVMGDSFN  TSLFKQTFQR  IFTKDFNGDF  RMAFGATLDV  KTSRELKIAG  420
421   AIGPCVSLNV  KGPCVSENEL  GVGGTSQWKI  CGLDPTSTLG  IYFEVVNQHN  APIPQGGRGA  480
481   IQFVTHYQHS  STQRRIRVTT  IARNWADVQS  QLRHIEAAFD  QEAAAVLMAR  LGVFRAESEE  540
541   GPDVLRWLDR  QLIRLCQKFG  QYNKEDPTSF  RLSDSFSLYP  QFMFHLRRSP  FLQVFNNSPD  600
601   ESSYYRHHFA  RQDLTQSLIM  IQPILYSYSF  HGPPEPVLLD  SSSILADRIL  LMDTFFQIVI  660
661   YLGETIAQWR  KAGYQDMPEY  ENFKHLLQAP  LDDAQEILQA  RFPMPRYINT  EHGGSQARFL  720
721   LSKVNPSQTH  NNLYAWGQET  GAPILTDDVS  LQVFMDHLKK  LAVSSAC  767
Nucleotide CDS Sequence (FASTA)
1     ATGGCGACAT  ACCTGGAGTT  CATCCAGCAG  AATGAAGAAC  GGGATGGTGT  GCGTTTTAGC  60
61    TGGAATGTGT  GGCCTTCCAG  CCGGCTGGAG  GCTACAAGAA  TGGTTGTACC  CCTGGCTTGT  120
121   CTCCTTACTC  CTTTGAAAGA  ACGTCCAGAC  CTACCTCCTG  TACAATATGA  ACCTGTGCTT  180
181   TGCAGCAGGC  CAACTTGTAA  AGCTGTTCTC  AACCCACTTT  GTCAGGTTGA  TTATCGAGCA  240
241   AAACTTTGGG  CCTGTAATTT  CTGTTTTCAA  AGAAATCAGT  TTCCTCCGGC  TTATGGAGGC  300
301   ATATCTGAGG  TGAATCAGCC  TGCTGAATTG  ATGCCTCAAT  TTTCTACAAT  TGAGTACATG  360
361   ATACAGCGAG  GTGCTCAGTC  CCCTCTGATC  TTTCTCTATG  TGGTTGACAC  ATGCCTGGAG  420
421   GAAGATGACC  TTCAAGCACT  CAAAGAGTCC  CTGCAGATGT  CCCTGAGTCT  TCTTCCTCCA  480
481   GATGCTCTGG  TGGGTCTGAT  CACATTTGGA  AGGATGGTGC  AGGTTCATGA  ACTAAGCTGT  540
541   GAAGGAATCT  CCAAAAGTTA  TGTCTTCCGA  GGGACCAAGG  ATTTAACTGC  AAAGCAAATA  600
601   CAGGATATGT  TGGGCCTGAC  CAAGCCAGCC  ATGCCCATGC  AGCAAGCACG  ACCTGTGCAA  660
661   CCACAGGAGC  ACCCTTTTGC  TTCAACCAGA  TTTCTGCAGC  CTGTTCACAA  GATTGATATG  720
721   AACCTCACTG  ATCTTCTTGG  GGAGCTACAG  AGGGACCCAT  GGCCAGTAAC  TCAGGGGAAG  780
781   AGACCTTTGC  GATCCACTGG  CGTTGCTTTG  TCCATTGCTG  TTGGCTTGCT  GGAGGGCACT  840
841   TTTCCAAACA  CGGGAGCCAG  GATCATGCTG  TTTACTGGAG  GTCCCCCTAC  CCAAGGGCCT  900
901   GGCATGGTGG  TTGGAGATGA  ATTAAAGATT  CCTATTCGTT  CTTGGCATGA  TATTGAGAAA  960
961   GATAATGCAC  GATTCATGAA  AAAGGCAACG  AAGCACTATG  AGATGCTTGC  TAATCGAACA  1020
1021  GCTGCAAATG  GTCACTGCAT  TGATATTTAT  GCTTGTGCCC  TTGATCAAAC  TGGACTTTTG  1080
1081  GAGATGAAAT  GTTGTGCAAA  TCTTACTGGA  GGCTACATGG  TAATGGGAGA  TTCTTTCAAC  1140
1141  ACTTCTCTCT  TCAAGCAGAC  ATTCCAAAGA  ATCTTTACTA  AAGATTTTAA  TGGAGATTTC  1200
1201  CGAATGGCAT  TTGGTGCTAC  TTTGGACGTA  AAGACCTCTC  GGGAACTGAA  GATTGCAGGA  1260
1261  GCCATTGGTC  CATGCGTATC  TCTGAATGTG  AAAGGACCGT  GTGTGTCAGA  AAATGAACTT  1320
1321  GGTGTTGGTG  GCACGAGTCA  GTGGAAAATC  TGTGGCCTAG  ATCCTACATC  TACACTTGGC  1380
1381  ATCTATTTTG  AAGTTGTCAA  TCAGCACAAC  GCCCCGATCC  CCCAAGGAGG  CAGAGGAGCG  1440
1441  ATCCAATTTG  TCACGCATTA  TCAGCACTCC  AGCACCCAGA  GACGCATCCG  CGTGACCACC  1500
1501  ATCGCCCGAA  ATTGGGCAGA  TGTACAGAGT  CAGCTCAGGC  ACATAGAAGC  AGCATTTGAC  1560
1561  CAGGAGGCTG  CAGCAGTCTT  GATGGCACGG  CTTGGGGTGT  TCCGAGCGGA  GTCAGAGGAG  1620
1621  GGACCTGATG  TGCTCCGGTG  GCTGGACCGA  CAACTCATCC  GACTGTGTCA  AAAGTTTGGA  1680
1681  CAGTATAACA  AAGAAGACCC  CACTTCTTTT  AGGTTATCAG  ATTCCTTTTC  TCTGTATCCT  1740
1741  CAGTTCATGT  TCCATCTGAG  AAGATCTCCA  TTTCTTCAAG  TGTTTAACAA  TAGTCCTGAT  1800
1801  GAGTCGTCAT  ATTACAGACA  TCATTTTGCC  CGGCAGGACC  TGACCCAGTC  CCTCATCATG  1860
1861  ATCCAGCCCA  TTCTCTACTC  TTATTCCTTT  CATGGGCCAC  CAGAGCCAGT  ACTCTTGGAT  1920
1921  AGCAGCAGCA  TTCTAGCTGA  CAGAATTTTG  CTGATGGATA  CTTTCTTTCA  AATTGTCATT  1980
1981  TATCTTGGTG  AGACCATAGC  CCAATGGCGT  AAAGCTGGCT  ACCAGGACAT  GCCCGAGTAC  2040
2041  GAAAACTTCA  AGCACCTTCT  GCAGGCACCA  CTGGATGATG  CTCAAGAAAT  TCTGCAAGCA  2100
2101  CGCTTCCCGA  TGCCACGTTA  CATTAACACA  GAGCATGGAG  GCAGTCAGGC  TCGATTCCTT  2160
2161  TTGTCCAAAG  TGAACCCATC  TCAGACACAC  AATAACCTCT  ATGCTTGGGG  CCAGGAAACT  2220
2221  GGAGCACCCA  TCCTAACTGA  TGATGTTAGC  CTGCAGGTGT  TCATGGACCA  TTTGAAGAAG  2280
2281  CTGGCTGTCT  CCAGTGCCTG  CTAA  2304

▼ KEYWORD

ID
Family
Complete proteome
Cytoplasm
Cytoplasmic vesicle
Endoplasmic reticulum
ER-Golgi transport
Membrane
Metal-binding
Protein transport
Reference proteome
Transport
Zinc

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
COPII vesicle coat
Cellular Component
Cytosol
Cellular Component
Endoplasmic reticulum membrane
Cellular Component
Golgi membrane
Molecular Function
Zinc ion binding
Biological Process
COPII-coated vesicle budding
Biological Process
Intracellular protein transport

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Maf-3127Macaca fascicularis100.00.01603
LLPS-Mal-1565Mandrillus leucophaeus100.00.01603
LLPS-Paa-4444Papio anubis100.00.01603
LLPS-Cea-4230Cercocebus atys99.870.01601
LLPS-Chs-0765Chlorocebus sabaeus99.740.01599
LLPS-Rhb-1899Rhinopithecus bieti99.610.01596
LLPS-Hos-1741Homo sapiens99.480.01597
LLPS-Poa-3291Pongo abelii99.480.01597
LLPS-Gog-3796Gorilla gorilla99.480.01597
LLPS-Pat-2689Pan troglodytes99.220.01595
LLPS-Pap-4178Pan paniscus99.220.01595
LLPS-Aon-4791Aotus nancymaae98.70.01586
LLPS-Caj-0210Callithrix jacchus98.70.01583
LLPS-Fec-3847Felis catus97.780.01576
LLPS-Ict-4276Ictidomys tridecemlineatus97.780.01577
LLPS-Urm-1170Ursus maritimus97.650.01574
LLPS-Caf-2412Canis familiaris97.520.01573
LLPS-Cas-3354Carlito syrichta97.520.01564
LLPS-Mup-3414Mustela putorius furo97.520.01571
LLPS-Mea-4227Mesocricetus auratus97.480.0 563
LLPS-Mam-0205Macaca mulatta97.390.01541
LLPS-Sus-3723Sus scrofa97.260.01571
LLPS-Mum-4028Mus musculus97.260.01566
LLPS-Myl-2710Myotis lucifugus97.130.01565
LLPS-Ova-0210Ovis aries97.00.01561
LLPS-Ran-3895Rattus norvegicus97.00.01556
LLPS-Loa-3898Loxodonta africana96.480.01546
LLPS-Eqc-2679Equus caballus96.480.01555
LLPS-Bot-1716Bos taurus96.470.01551
LLPS-Orc-2362Oryctolagus cuniculus96.350.01554
LLPS-Aim-2287Ailuropoda melanoleuca95.730.01360
LLPS-Mod-3253Monodelphis domestica95.690.01548
LLPS-Fud-0659Fukomys damarensis94.910.01535
LLPS-Sah-0240Sarcophilus harrisii94.280.01529
LLPS-Anp-2628Anas platyrhynchos93.730.01519
LLPS-Dio-3607Dipodomys ordii93.730.01491
LLPS-Cap-3523Cavia porcellus93.610.01516
LLPS-Gaga-1759Gallus gallus93.210.01513
LLPS-Meg-2890Meleagris gallopavo93.080.01510
LLPS-Fia-3322Ficedula albicollis92.820.01505
LLPS-Tag-2004Taeniopygia guttata92.820.01507
LLPS-Pes-3806Pelodiscus sinensis92.30.01493
LLPS-Xet-2867Xenopus tropicalis92.30.01504
LLPS-Anc-0093Anolis carolinensis92.050.01498
LLPS-Leo-2494Lepisosteus oculatus89.950.01471
LLPS-Ora-1189Ornithorhynchus anatinus89.70.0 884
LLPS-Lac-2910Latimeria chalumnae89.570.01412
LLPS-Orn-1727Oreochromis niloticus87.470.01433
LLPS-Scf-0941Scleropages formosus87.210.01423
LLPS-Gaa-0692Gasterosteus aculeatus87.080.01434
LLPS-Pof-2530Poecilia formosa86.960.01432
LLPS-Scm-2416Scophthalmus maximus86.680.01421
LLPS-Asm-0543Astyanax mexicanus86.680.01414
LLPS-Xim-2272Xiphophorus maculatus86.570.01426
LLPS-Orl-3517Oryzias latipes86.310.01410
LLPS-Dar-3965Danio rerio85.770.01408
LLPS-Nol-2466Nomascus leucogenys84.730.01388
LLPS-Icp-2240Ictalurus punctatus84.640.01378
LLPS-Tar-1498Takifugu rubripes84.620.01387
LLPS-Ten-1353Tetraodon nigroviridis84.40.01367
LLPS-Otg-3036Otolemur garnettii75.130.01115
LLPS-Drm-0633Drosophila melanogaster73.210.01196
LLPS-Cii-1917Ciona intestinalis71.350.01182
LLPS-Cis-1020Ciona savignyi69.460.01144
LLPS-Cae-0674Caenorhabditis elegans61.960.0 685
LLPS-Crn-0713Cryptococcus neoformans61.870.0 956
LLPS-Abg-0042Absidia glauca61.870.0 954
LLPS-Spr-0518Sporisorium reilianum61.770.0 958
LLPS-Usm-0891Ustilago maydis61.380.0 972
LLPS-Miv-0260Microbotryum violaceum60.770.0 947
LLPS-Mel-0226Melampsora laricipopulina60.50.0 956
LLPS-Pug-1180Puccinia graminis60.450.0 950
LLPS-Put-1187Puccinia triticina60.140.0 705
LLPS-Tum-1169Tuber melanosporum59.370.0 907
LLPS-Trr-0571Trichoderma reesei58.870.0 905
LLPS-Blg-1585Blumeria graminis58.720.0 900
LLPS-Asn-1567Aspergillus nidulans58.680.0 878
LLPS-Scs-1051Sclerotinia sclerotiorum58.630.0 895
LLPS-Coo-1346Colletotrichum orbiculare58.440.0 889
LLPS-Mao-0777Magnaporthe oryzae58.390.0 889
LLPS-Nec-0214Neurospora crassa58.170.0 884
LLPS-Trv-1144Trichoderma virens58.140.0 889
LLPS-Fuo-0170Fusarium oxysporum58.080.0 887
LLPS-Fuv-0744Fusarium verticillioides58.080.0 886
LLPS-Cog-0708Colletotrichum gloeosporioides58.010.0 880
LLPS-Asc-0204Aspergillus clavatus57.990.0 863
LLPS-Cogr-0347Colletotrichum graminicola57.980.0 890
LLPS-Gag-0180Gaeumannomyces graminis57.970.0 885
LLPS-Map-1129Magnaporthe poae57.970.0 887
LLPS-Aso-0160Aspergillus oryzae57.950.0 887
LLPS-Asf-0137Aspergillus flavus57.950.0 887
LLPS-Asni-0312Aspergillus niger57.890.0 879
LLPS-Beb-0530Beauveria bassiana57.870.0 891
LLPS-Lem-1377Leptosphaeria maculans57.820.0 878
LLPS-Scp-1052Schizosaccharomyces pombe57.820.0 876
LLPS-Ast-0880Aspergillus terreus57.760.0 870
LLPS-Pyt-0904Pyrenophora teres57.540.0 889
LLPS-Nef-0258Neosartorya fischeri57.480.0 864
LLPS-Pytr-0389Pyrenophora triticirepentis57.40.0 885
LLPS-Dos-0349Dothistroma septosporum57.390.0 886
LLPS-Asfu-0467Aspergillus fumigatus57.370.0 860
LLPS-Fus-1441Fusarium solani57.290.0 875
LLPS-Scj-0960Schizosaccharomyces japonicus57.220.0 891
LLPS-Ved-0454Verticillium dahliae57.20.0 878
LLPS-Zyt-0552Zymoseptoria tritici57.030.0 884
LLPS-Yal-1564Yarrowia lipolytica55.70.0 870
LLPS-Phn-0901Phaeosphaeria nodorum55.470.0 857
LLPS-Scc-0371Schizosaccharomyces cryophilus55.390.0 861
LLPS-Asg-1355Ashbya gossypii52.170.0 787
LLPS-Gas-0982Galdieria sulphuraria51.940.0 810
LLPS-Chc-0427Chondrus crispus51.510.0 787
LLPS-Php-0403Physcomitrella patens50.650.0 795
LLPS-Sac-0903Saccharomyces cerevisiae49.930.0 761
LLPS-Phv-0369Phaseolus vulgaris48.840.0 754
LLPS-Brd-1837Brachypodium distachyon48.770.0 745
LLPS-Glm-2030Glycine max48.750.0 748
LLPS-Amt-1074Amborella trichopoda48.70.0 755
LLPS-Lep-0330Leersia perrieri48.70.0 744
LLPS-Orm-1191Oryza meridionalis48.580.0 740
LLPS-Viv-1690Vitis vinifera48.50.0 756
LLPS-Org-0656Oryza glaberrima48.450.0 740
LLPS-Ori-0503Oryza indica48.450.0 740
LLPS-Orni-1531Oryza nivara48.450.0 738
LLPS-Orgl-1305Oryza glumaepatula48.450.0 740
LLPS-Sem-1791Selaginella moellendorffii48.440.0 724
LLPS-Dac-0902Daucus carota48.420.0 733
LLPS-Orb-0760Oryza barthii48.370.0 632
LLPS-Sei-1688Setaria italica48.120.0 726
LLPS-Cus-0442Cucumis sativus48.060.0 744
LLPS-Arl-2445Arabidopsis lyrata48.040.0 744
LLPS-Tra-1231Triticum aestivum48.040.0 730
LLPS-Hov-0443Hordeum vulgare48.040.0 731
LLPS-Sob-1918Sorghum bicolor47.940.0 733
LLPS-Met-0325Medicago truncatula47.910.0 749
LLPS-Brr-1465Brassica rapa47.870.0 746
LLPS-Mae-1907Manihot esculenta47.80.0 753
LLPS-Orbr-2166Oryza brachyantha47.80.0 714
LLPS-Osl-0469Ostreococcus lucimarinus47.80.0 676
LLPS-Gor-2318Gossypium raimondii47.790.0 744
LLPS-Vir-0064Vigna radiata47.670.0 748
LLPS-Nia-1424Nicotiana attenuata47.610.0 738
LLPS-Zem-0952Zea mays47.550.0 723
LLPS-Via-1965Vigna angularis47.550.0 748
LLPS-Sol-0682Solanum lycopersicum47.50.0 735
LLPS-Prp-2157Prunus persica47.460.0 748
LLPS-Sot-1021Solanum tuberosum47.370.0 732
LLPS-Hea-2309Helianthus annuus47.330.0 723
LLPS-Bro-2408Brassica oleracea47.210.0 740
LLPS-Orp-1250Oryza punctata46.960.0 721
LLPS-Coc-0447Corchorus capsularis46.940.0 726
LLPS-Thc-1840Theobroma cacao46.890.0 737
LLPS-Ors-0867Oryza sativa46.70.0 699
LLPS-Cym-0143Cyanidioschyzon merolae46.690.0 677
LLPS-Brn-2119Brassica napus46.340.0 717
LLPS-Mua-1920Musa acuminata46.30.0 680
LLPS-Pot-2536Populus trichocarpa46.170.0 719
LLPS-Art-0405Arabidopsis thaliana46.080.0 723
LLPS-Chr-1157Chlamydomonas reinhardtii45.820.0 687
LLPS-Kop-1321Komagataella pastoris45.060.0 655
LLPS-Orr-0018Oryza rufipogon44.040.0 672
LLPS-Tru-2010Triticum urartu43.474e-170 512