• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Spr-0706
sr13189

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: RNA polymerase II transcription factor B subunit 2
Gene Name: sr13189
Ensembl Gene: sr13189
Ensembl Protein: CBQ72481
Organism: Sporisorium reilianum
Taxa ID: 999809
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblCBQ72481CBQ72481
UniProtE6ZZ24, E6ZZ24_SPORE
GeneBankFQ311463CBQ72481.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSTQRNTPGP  GQGVTSTARG  GNNNALSISE  HSKAARIGAE  TIDDFLDRQP  RSVLIRLYEK  60
61    PASCLAIFRL  LPMMARQLIM  HMLFLDVPLA  ADDFMAWIKK  EARKDFDAAV  DKLSRLSIVQ  120
121   LKTTAAKQIL  LLNAVFTDGM  RRALTGGGKH  RSFGVPCDTE  DKNAVDVAFL  DEYARTKWET  180
181   ILHYMVGSDN  SSTPREPVLY  LLRRSNLMQP  RSTSTSSSSG  GLNITSRGFQ  FLLEDVNTQL  240
241   WDLLLQYLDM  AEERNMDLVE  VLAFLFMLGS  LELGRDYSTE  ELPETQLHML  EDFRDYGLVY  300
301   QRKASSRRFY  PTRLATTLTS  SAAVPLLSSN  GTEQEERGYI  ILETNYRLYA  YTSNRLRVAV  360
361   LSLFVTIKAR  FPNLVVGSIT  RDSVKSALAN  GITAEQIITY  LTHHAHVQMH  RNDPLLPVTV  420
421   SDQIRLWERE  KNRVQQNLGS  LFTDFTSQFD  FEEVRNYAKQ  LGVLVWEDEG  KRRFFVDEAG  480
481   NVPVRDYIRR  RRA  493

▼ KEYWORD

ID
Family
Complete proteome
DNA damage
DNA repair
Nucleus
Reference proteome
Transcription
Transcription regulation

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Nucleotide-excision repair factor 3 complex
Cellular Component
Transcription factor TFIIH core complex
Cellular Component
Transcription factor TFIIH holo complex
Molecular Function
ATPase activator activity
Molecular Function
Double-stranded DNA binding
Biological Process
Nucleotide-excision repair
Biological Process
Phosphorylation of RNA polymerase II C-terminal domain
Biological Process
Transcription by RNA polymerase II

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Usm-0767Ustilago maydis93.10.0 906
LLPS-Scj-1262Schizosaccharomyces japonicus53.13e-153 451
LLPS-Scc-1606Schizosaccharomyces cryophilus52.882e-153 452
LLPS-Scp-0817Schizosaccharomyces pombe52.763e-151 446
LLPS-Yal-0890Yarrowia lipolytica52.167e-152 449
LLPS-Put-0578Puccinia triticina49.386e-82 267
LLPS-Abg-1684Absidia glauca48.096e-150 444
LLPS-Pug-0881Puccinia graminis47.631e-127 399
LLPS-Mel-0933Melampsora laricipopulina47.62e-133 401
LLPS-Miv-0894Microbotryum violaceum47.592e-122 375
LLPS-Tum-0728Tuber melanosporum45.937e-119 364
LLPS-Xet-2190Xenopus tropicalis45.215e-85 275
LLPS-Pes-1235Pelodiscus sinensis44.126e-1993.2
LLPS-Dos-1570Dothistroma septosporum44.083e-113 350
LLPS-Mod-0004Monodelphis domestica43.793e-115 355
LLPS-Paa-3317Papio anubis43.586e-113 349
LLPS-Mal-0595Mandrillus leucophaeus43.586e-113 349
LLPS-Caj-1107Callithrix jacchus43.587e-113 348
LLPS-Gog-0566Gorilla gorilla43.586e-113 349
LLPS-Cea-0797Cercocebus atys43.586e-113 349
LLPS-Chs-4374Chlorocebus sabaeus43.586e-113 349
LLPS-Maf-1697Macaca fascicularis43.586e-113 349
LLPS-Nol-0069Nomascus leucogenys43.586e-113 349
LLPS-Mam-2149Macaca mulatta43.582e-112 349
LLPS-Poa-0660Pongo abelii43.586e-113 349
LLPS-Rhb-4809Rhinopithecus bieti43.589e-113 348
LLPS-Man-3858Macaca nemestrina43.582e-112 349
LLPS-Pat-3712Pan troglodytes43.586e-113 349
LLPS-Pap-4641Pan paniscus43.586e-113 349
LLPS-Hos-0151Homo sapiens43.586e-113 349
LLPS-Scs-0937Sclerotinia sclerotiorum43.431e-101 318
LLPS-Aon-3414Aotus nancymaae43.361e-111 345
LLPS-Zyt-1111Zymoseptoria tritici43.044e-95 303
LLPS-Cii-2048Ciona intestinalis43.044e-55 190
LLPS-Phn-0858Phaeosphaeria nodorum42.961e-97 308
LLPS-Anc-1426Anolis carolinensis42.732e-113 350
LLPS-Ran-1158Rattus norvegicus42.682e-114 352
LLPS-Mum-4682Mus musculus42.689e-115 353
LLPS-Gaa-0044Gasterosteus aculeatus42.581e-110 343
LLPS-Dar-1066Danio rerio42.499e-114 352
LLPS-Scf-3717Scleropages formosus42.463e-112 347
LLPS-Caf-4104Canis familiaris42.382e-114 353
LLPS-Chr-1438Chlamydomonas reinhardtii42.367e-30 126
LLPS-Mea-0677Mesocricetus auratus42.264e-114 352
LLPS-Pytr-1549Pyrenophora triticirepentis42.261e-113 351
LLPS-Otg-2830Otolemur garnettii42.233e-113 349
LLPS-Fud-2092Fukomys damarensis42.182e-98 309
LLPS-Eqc-0258Equus caballus42.176e-114 351
LLPS-Loa-0759Loxodonta africana42.179e-114 351
LLPS-Lem-1134Leptosphaeria maculans41.982e-105 330
LLPS-Pyt-1428Pyrenophora teres41.987e-113 349
LLPS-Aim-3896Ailuropoda melanoleuca41.961e-113 350
LLPS-Sus-0538Sus scrofa41.962e-112 347
LLPS-Ict-0023Ictidomys tridecemlineatus41.962e-113 350
LLPS-Cap-0698Cavia porcellus41.965e-113 350
LLPS-Orn-1939Oreochromis niloticus41.92e-109 339
LLPS-Icp-1458Ictalurus punctatus41.764e-110 342
LLPS-Ova-3736Ovis aries41.752e-113 350
LLPS-Cas-1341Carlito syrichta41.752e-112 347
LLPS-Fec-3835Felis catus41.752e-113 350
LLPS-Urm-3201Ursus maritimus41.759e-113 348
LLPS-Asg-0652Ashbya gossypii41.684e-115 356
LLPS-Scm-3768Scophthalmus maximus41.631e-111 345
LLPS-Asm-3251Astyanax mexicanus41.584e-110 342
LLPS-Bot-3665Bos taurus41.541e-112 348
LLPS-Xim-3239Xiphophorus maculatus41.544e-107 334
LLPS-Orl-0277Oryzias latipes41.435e-111 344
LLPS-Asc-1659Aspergillus clavatus41.423e-110 342
LLPS-Ten-0568Tetraodon nigroviridis41.392e-110 342
LLPS-Mao-1079Magnaporthe oryzae41.352e-110 343
LLPS-Asf-0420Aspergillus flavus41.347e-108 336
LLPS-Aso-1209Aspergillus oryzae41.347e-108 336
LLPS-Tar-3140Takifugu rubripes41.294e-111 344
LLPS-Asfu-1004Aspergillus fumigatus41.211e-107 335
LLPS-Asni-0674Aspergillus niger40.886e-106 331
LLPS-Asn-1168Aspergillus nidulans40.794e-106 332
LLPS-Trr-0271Trichoderma reesei40.591e-100 317
LLPS-Ast-1351Aspergillus terreus40.592e-102 322
LLPS-Blg-0440Blumeria graminis40.512e-112 348
LLPS-Map-1365Magnaporthe poae40.494e-102 322
LLPS-Nef-1040Neosartorya fischeri40.384e-103 323
LLPS-Sac-1004Saccharomyces cerevisiae40.351e-112 350
LLPS-Lac-2693Latimeria chalumnae40.264e-100 315
LLPS-Drm-1711Drosophila melanogaster40.088e-102 321
LLPS-Pof-2563Poecilia formosa39.587e-93 297
LLPS-Gag-0439Gaeumannomyces graminis39.442e-100 317
LLPS-Cym-0779Cyanidioschyzon merolae39.14e-24 110
LLPS-Fus-0786Fusarium solani39.18e-101 318
LLPS-Kop-0508Komagataella pastoris38.762e-105 332
LLPS-Cogr-0549Colletotrichum graminicola38.543e-89 288
LLPS-Fuo-0771Fusarium oxysporum38.492e-101 320
LLPS-Trv-1538Trichoderma virens38.453e-100 317
LLPS-Beb-0889Beauveria bassiana38.41e-93 300
LLPS-Cis-1527Ciona savignyi38.347e-82 268
LLPS-Fuv-1483Fusarium verticillioides38.292e-100 317
LLPS-Nec-1228Neurospora crassa38.176e-96 306
LLPS-Dio-4049Dipodomys ordii37.797e-26 108
LLPS-Crn-1327Cryptococcus neoformans36.971e-75 253
LLPS-Coo-1604Colletotrichum orbiculare36.961e-88 287
LLPS-Ved-1552Verticillium dahliae35.522e-86 280
LLPS-Tru-1567Triticum urartu34.692e-41 157
LLPS-Chc-1180Chondrus crispus32.843e-60 211
LLPS-Sei-0821Setaria italica32.836e-67 228
LLPS-Orgl-2032Oryza glumaepatula32.837e-69 233
LLPS-Org-0485Oryza glaberrima32.832e-68 232
LLPS-Orr-1160Oryza rufipogon32.837e-69 233
LLPS-Orbr-1804Oryza brachyantha32.832e-69 235
LLPS-Ors-1114Oryza sativa32.837e-69 233
LLPS-Sem-0134Selaginella moellendorffii32.825e-61 213
LLPS-Orp-2344Oryza punctata32.762e-67 230
LLPS-Lep-1552Leersia perrieri32.624e-65 223
LLPS-Orm-1215Oryza meridionalis32.624e-68 231
LLPS-Php-1166Physcomitrella patens32.377e-73 244
LLPS-Tra-0085Triticum aestivum32.172e-65 224
LLPS-Coc-1386Corchorus capsularis32.15e-68 235
LLPS-Mua-2038Musa acuminata32.032e-66 227
LLPS-Ori-2367Oryza indica31.985e-68 231
LLPS-Osl-1139Ostreococcus lucimarinus31.925e-55 197
LLPS-Prp-1501Prunus persica31.922e-63 219
LLPS-Brd-1575Brachypodium distachyon31.846e-63 219
LLPS-Mae-2686Manihot esculenta31.841e-68 233
LLPS-Thc-2150Theobroma cacao31.812e-68 233
LLPS-Glm-2782Glycine max31.63e-65 224
LLPS-Sob-1248Sorghum bicolor31.592e-67 230
LLPS-Amt-2221Amborella trichopoda31.586e-66 226
LLPS-Pot-2738Populus trichocarpa31.492e-65 224
LLPS-Hea-0906Helianthus annuus31.414e-67 229
LLPS-Phv-0795Phaseolus vulgaris31.392e-65 224
LLPS-Via-1240Vigna angularis31.31e-63 219
LLPS-Cus-2378Cucumis sativus31.268e-66 225
LLPS-Orb-0481Oryza barthii31.264e-67 230
LLPS-Nia-1774Nicotiana attenuata31.182e-61 219
LLPS-Gas-1269Galdieria sulphuraria31.099e-45 171
LLPS-Zem-1275Zea mays31.098e-66 225
LLPS-Brn-1147Brassica napus31.014e-59 207
LLPS-Bro-2621Brassica oleracea31.014e-60 212
LLPS-Brr-2657Brassica rapa31.019e-60 209
LLPS-Dac-2009Daucus carota30.926e-57 201
LLPS-Sol-2177Solanum lycopersicum30.75e-66 226
LLPS-Met-1198Medicago truncatula30.63e-62 216
LLPS-Cae-0512Caenorhabditis elegans30.598e-53 191
LLPS-Art-2895Arabidopsis thaliana30.527e-61 213
LLPS-Arl-1443Arabidopsis lyrata30.322e-62 216
LLPS-Gor-1426Gossypium raimondii30.027e-69 233
LLPS-Vir-2010Vigna radiata28.838e-51 186
LLPS-Orni-2025Oryza nivara28.541e-62 218
LLPS-Viv-2062Vitis vinifera26.784e-1063.5
LLPS-Sot-1427Solanum tuberosum24.681e-0755.5