• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Sah-0442
PABPC1L

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Polyadenylate-binding protein
Gene Name: PABPC1L
Ensembl Gene: ENSSHAG00000011446.1
Ensembl Protein: ENSSHAP00000013386.1
Organism: Sarcophilus harrisii
Taxa ID: 9305
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
NucleolusPredicted from orthologs(View)

▼ FUNCTION

Binds the poly(A) tail of mRNA.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSSHAT00000013497.1ENSSHAP00000013386.1
UniProtG3WD81, G3WD81_SARHA
GeneBankAEFK01024766

▼ SEQUENCE

Protein Sequence (FASTA)
1     QVVCDENGSR  GFGFVHFETQ  EAANQAISTM  NGMLLNDRKV  FVGHFKSRQE  REAELGARAL  60
61    EFTNIYVKNF  EEDVDDQCLE  ELFSEFGKTL  SVKVMVDENG  HSRGFGFVNF  EKHEEAQKAV  120
121   NSMNGKALGG  RVLYVGRAQK  RTERQGELKR  RFEQMKQERV  NRYQGVNLYV  KNLDDVIDDE  180
181   KLRKEFSPYG  VITSAKVMTE  GGHSKGFGFV  CFSSPEEATK  AVTEMNGRIV  STKPLYVALA  240
241   QRKEERKAIL  TNQYMQRISV  LRNINGPVFP  QPTNYFLPAI  PQSPTRASFY  SPSTMAPIRP  300
301   APRWTSYSPR  SLSFVVFLPA  TPRRSTSNIS  TVRQASTQVP  RAGPHMQRVV  NIGTQTMGTG  360
361   CPGSPGQAIP  QYKYSSAMPN  AHQVLNSLKK  ISVMERAVHI  QGQEPLTASM  LASAPPQEQK  420
421   QMLGDRLYPL  IYGVHAQLAG  KITGMLLEID  NSELLLMLES  PESLHSKIEE  AVAALQAQEV  480
481   ME  482
Nucleotide CDS Sequence (FASTA)
1     CAGGTGGTAT  GTGATGAAAA  CGGCTCCAGG  GGATTTGGCT  TTGTCCACTT  TGAGACACAA  60
61    GAGGCTGCAA  ACCAAGCAAT  CAGCACTATG  AATGGGATGC  TACTTAATGA  CCGCAAAGTT  120
121   TTTGTGGGCC  ACTTCAAGTC  TCGGCAGGAA  CGGGAGGCAG  AGCTGGGGGC  ACGAGCGCTA  180
181   GAATTCACCA  ACATCTATGT  CAAGAACTTT  GAGGAAGACG  TGGATGATCA  GTGCCTGGAG  240
241   GAACTATTCT  CCGAGTTTGG  AAAGACTCTG  AGTGTGAAGG  TGATGGTAGA  TGAAAATGGC  300
301   CATTCCCGAG  GTTTCGGTTT  TGTTAACTTT  GAGAAGCATG  AGGAAGCTCA  GAAGGCTGTG  360
361   AACAGCATGA  ATGGGAAGGC  GCTCGGGGGT  CGAGTCCTGT  ACGTTGGACG  GGCCCAGAAA  420
421   AGGACAGAGA  GGCAGGGGGA  GCTGAAGCGT  AGATTCGAGC  AGATGAAGCA  GGAGAGAGTG  480
481   AACCGCTACC  AGGGTGTGAA  CCTTTATGTG  AAGAATTTGG  ATGATGTCAT  TGATGATGAG  540
541   AAGCTACGGA  AGGAGTTTTC  TCCATATGGA  GTGATCACCA  GTGCTAAAGT  GATGACAGAG  600
601   GGTGGCCACA  GCAAGGGGTT  TGGCTTTGTG  TGTTTTTCCT  CCCCAGAAGA  GGCTACAAAG  660
661   GCCGTGACAG  AGATGAACGG  CCGGATTGTT  AGTACCAAGC  CCCTCTATGT  GGCCCTGGCC  720
721   CAACGCAAGG  AGGAGCGGAA  GGCCATTCTC  ACTAACCAGT  ACATGCAACG  CATCTCTGTC  780
781   CTAAGGAACA  TAAATGGCCC  CGTCTTTCCC  CAACCCACCA  ATTATTTCCT  GCCTGCTATC  840
841   CCCCAGTCAC  CTACCCGAGC  ATCCTTCTAC  AGTCCCAGCA  CCATGGCCCC  CATTCGGCCT  900
901   GCCCCAAGGT  GGACCAGCTA  TTCTCCTAGG  TCTTTGTCGT  TTGTTGTCTT  CTTGCCAGCC  960
961   ACCCCCCGGC  GCTCCACCTC  CAACATCAGT  ACTGTCCGGC  AGGCCTCTAC  TCAGGTGCCC  1020
1021  CGGGCAGGGC  CACACATGCA  GAGAGTGGTC  AATATTGGGA  CTCAGACCAT  GGGAACTGGG  1080
1081  TGTCCAGGCT  CCCCAGGTCA  AGCCATCCCA  CAATACAAGT  ACTCCTCAGC  TATGCCTAAT  1140
1141  GCACATCAGG  TTCTTAACTC  TTTAAAAAAA  ATTTCAGTAA  TGGAGAGAGC  TGTGCATATC  1200
1201  CAAGGGCAGG  AGCCTTTAAC  TGCTTCTATG  TTGGCCTCAG  CCCCACCCCA  GGAACAGAAG  1260
1261  CAAATGCTTG  GTGACAGACT  CTATCCACTC  ATTTATGGGG  TACACGCTCA  GCTGGCTGGC  1320
1321  AAGATCACTG  GCATGCTGCT  GGAGATTGAC  AACTCAGAGC  TGCTGCTGAT  GCTGGAATCT  1380
1381  CCAGAATCGC  TCCATTCCAA  GATTGAAGAA  GCAGTAGCTG  CACTCCAAGC  ACAAGAAGTC  1440
1441  ATGGAG  1446

▼ KEYWORD

ID
Family
Complete proteome
Cytoplasm
Reference proteome
Repeat
RNA-binding

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Molecular Function
RNA binding
Biological Process
Chromatin remodeling
Biological Process
Chromatin-mediated maintenance of transcription
Biological Process
MRNA polyadenylation
Biological Process
Nucleus localization
Biological Process
Oocyte maturation

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Mod-1154Monodelphis domestica86.710.0 791
LLPS-Pes-2020Pelodiscus sinensis80.282e-159 466
LLPS-Urm-0107Ursus maritimus79.488e-163 473
LLPS-Maf-4216Macaca fascicularis74.680.0 635
LLPS-Gog-4698Gorilla gorilla74.530.0 628
LLPS-Poa-1096Pongo abelii74.320.0 631
LLPS-Cea-1044Cercocebus atys74.260.0 634
LLPS-Mal-3525Mandrillus leucophaeus74.260.0 634
LLPS-Rhb-1116Rhinopithecus bieti74.110.0 631
LLPS-Hos-2049Homo sapiens74.110.0 630
LLPS-Chs-3821Chlorocebus sabaeus74.050.0 630
LLPS-Meg-0711Meleagris gallopavo73.470.0 638
LLPS-Paa-2310Papio anubis73.030.0 626
LLPS-Otg-2429Otolemur garnettii72.770.0 642
LLPS-Mup-4223Mustela putorius furo72.650.0 636
LLPS-Fec-4418Felis catus72.650.0 635
LLPS-Caj-2482Callithrix jacchus72.420.0 632
LLPS-Aon-3891Aotus nancymaae72.210.0 629
LLPS-Man-2602Macaca nemestrina72.210.0 607
LLPS-Fia-1569Ficedula albicollis72.180.0 546
LLPS-Anc-0689Anolis carolinensis71.580.0 635
LLPS-Dio-3521Dipodomys ordii71.40.0 619
LLPS-Ict-4169Ictidomys tridecemlineatus71.370.0 618
LLPS-Ova-2725Ovis aries71.150.0 616
LLPS-Loa-2808Loxodonta africana71.090.0 637
LLPS-Cas-0443Carlito syrichta70.950.0 626
LLPS-Tag-0263Taeniopygia guttata70.40.0 635
LLPS-Sus-1489Sus scrofa69.080.0 601
LLPS-Ere-0730Erinaceus europaeus69.050.0 595
LLPS-Leo-2262Lepisosteus oculatus68.820.0 620
LLPS-Fud-2226Fukomys damarensis68.130.0 564
LLPS-Cap-3822Cavia porcellus67.680.0 581
LLPS-Myl-2889Myotis lucifugus66.950.0 592
LLPS-Mum-2049Mus musculus66.310.0 596
LLPS-Ora-0485Ornithorhynchus anatinus66.090.0 592
LLPS-Mea-0928Mesocricetus auratus66.090.0 594
LLPS-Aim-2318Ailuropoda melanoleuca66.090.0 595
LLPS-Ran-0034Rattus norvegicus66.090.0 594
LLPS-Bot-0676Bos taurus66.090.0 594
LLPS-Orc-0006Oryctolagus cuniculus66.090.0 594
LLPS-Pat-0096Pan troglodytes66.090.0 594
LLPS-Caf-0758Canis familiaris66.090.0 594
LLPS-Tut-0106Tursiops truncatus65.730.0 572
LLPS-Anp-0205Anas platyrhynchos65.520.0 585
LLPS-Gaga-1755Gallus gallus65.520.0 585
LLPS-Mam-1121Macaca mulatta64.440.0 586
LLPS-Pof-2411Poecilia formosa64.320.0 578
LLPS-Orn-0345Oreochromis niloticus64.240.0 577
LLPS-Scf-2272Scleropages formosus64.160.0 577
LLPS-Asm-0389Astyanax mexicanus63.820.0 581
LLPS-Xet-2658Xenopus tropicalis63.420.0 547
LLPS-Dar-0605Danio rerio63.380.0 576
LLPS-Xim-0002Xiphophorus maculatus63.360.0 555
LLPS-Abg-0396Absidia glauca62.961e-0758.5
LLPS-Tar-1585Takifugu rubripes62.960.0 564
LLPS-Icp-1353Ictalurus punctatus62.940.0 564
LLPS-Orl-1335Oryzias latipes62.880.0 561
LLPS-Scm-0124Scophthalmus maximus62.880.0 569
LLPS-Eqc-0520Equus caballus62.730.0 580
LLPS-Nol-2854Nomascus leucogenys62.550.0 548
LLPS-Gaa-0140Gasterosteus aculeatus62.110.0 570
LLPS-Lac-0500Latimeria chalumnae61.290.0 541
LLPS-Ten-0752Tetraodon nigroviridis61.030.0 543
LLPS-Pap-2020Pan paniscus58.470.0 536
LLPS-Cae-0679Caenorhabditis elegans55.944e-87 288
LLPS-Scj-1180Schizosaccharomyces japonicus55.61e-88 290
LLPS-Sac-0254Saccharomyces cerevisiae55.214e-88 287
LLPS-Cis-0525Ciona savignyi49.796e-131 400
LLPS-Drm-0098Drosophila melanogaster47.746e-124 382
LLPS-Cii-0093Ciona intestinalis47.363e-120 368
LLPS-Sem-1324Selaginella moellendorffii44.471e-95 308
LLPS-Pug-0751Puccinia graminis43.31e-97 318
LLPS-Crn-0202Cryptococcus neoformans43.254e-103 329
LLPS-Put-0391Puccinia triticina42.652e-94 305
LLPS-Php-2380Physcomitrella patens42.611e-95 309
LLPS-Scc-0164Schizosaccharomyces cryophilus42.355e-96 310
LLPS-Thc-1228Theobroma cacao41.961e-87 288
LLPS-Coc-1556Corchorus capsularis41.832e-88 290
LLPS-Scp-0021Schizosaccharomyces pombe41.651e-100 322
LLPS-Orp-0276Oryza punctata41.314e-87 287
LLPS-Amt-0481Amborella trichopoda41.096e-92 299
LLPS-Sei-0885Setaria italica41.018e-92 299
LLPS-Chc-0157Chondrus crispus40.977e-95 307
LLPS-Brd-0047Brachypodium distachyon40.891e-88 291
LLPS-Usm-0436Ustilago maydis40.822e-91 298
LLPS-Prp-0523Prunus persica40.769e-89 291
LLPS-Zem-0296Zea mays40.726e-90 294
LLPS-Gor-0295Gossypium raimondii40.686e-87 286
LLPS-Dac-0735Daucus carota40.621e-91 299
LLPS-Met-2644Medicago truncatula40.555e-87 286
LLPS-Nia-1755Nicotiana attenuata40.552e-94 306
LLPS-Sol-0565Solanum lycopersicum40.382e-93 303
LLPS-Sob-0152Sorghum bicolor40.381e-90 296
LLPS-Glm-1402Glycine max40.341e-89 293
LLPS-Arl-2426Arabidopsis lyrata40.122e-93 304
LLPS-Spr-0278Sporisorium reilianum39.969e-90 293
LLPS-Phv-0912Phaseolus vulgaris39.916e-87 286
LLPS-Asfu-0098Aspergillus fumigatus39.478e-95 310
LLPS-Sot-0545Solanum tuberosum39.282e-91 298
LLPS-Pot-2720Populus trichocarpa39.167e-90 294
LLPS-Yal-0100Yarrowia lipolytica38.944e-87 286
LLPS-Cus-0447Cucumis sativus38.948e-87 286
LLPS-Kop-1053Komagataella pastoris38.916e-88 288
LLPS-Asn-0437Aspergillus nidulans38.722e-94 308
LLPS-Viv-1105Vitis vinifera38.45e-87 286
LLPS-Cog-0096Colletotrichum gloeosporioides37.877e-89 292
LLPS-Nec-1339Neurospora crassa37.319e-90 296