• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Ten-0752

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Polyadenylate-binding protein
Ensembl Gene: ENSTNIG00000009153.1
Ensembl Protein: ENSTNIP00000012014.1
Organism: Tetraodon nigroviridis
Taxa ID: 99883
LLPS Type: Scaffold


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Droplet, Nuclear speckle, Nucleolus, P-body, Stress granule, Chromatoid body, Postsynaptic density, OthersPredicted from orthologs(View)

▼ FUNCTION

Binds the poly(A) tail of mRNA.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblENSTNIT00000012204.1ENSTNIP00000012014.1
UniProtH3CUT0, H3CUT0_TETNG

▼ SEQUENCE

Protein Sequence (FASTA)
1     MNPSAASYPM  ASLYVGDLHP  DVTEAMLYEK  FSPAGAILSI  RVCRDMITRR  SLGYAYVNFQ  60
61    QPADAERALD  TMNFDVIKGR  PVRIMWSQRD  PSLRKSGVGN  IFIKNLDKSI  DNKALYDTFS  120
121   AFGNILSCKV  VCDENGSKGY  GFVHFETQEA  AERAIEKMNG  MLLNDRKVFV  GRFKSRKERE  180
181   AELGARAREF  TNVYIKNFGD  DMDEEKLRDV  FNKYGNAMSI  RVMTDDSGKS  RGFGFVSFER  240
241   HEDAQKAVDE  MNGKEMNGKP  IYVGRAQKKV  ERQAELKRKF  EQMKQDRMTR  YQGVNLYVKN  300
301   LDDGIDDERL  RKEFSPFGTI  TSAKVMLEGG  RSKGFGFVCF  SSPEEATKAV  TEMNGRIVAT  360
361   KPLYVALAQR  KEERQAHLTN  QYMQRMASVR  AVPNPVINPY  QPAPPSGYFM  TAIPQTQNRG  420
421   AYYPAAGQMA  QLRPSPRWPT  QGVRPQHFQN  MQSAMRSSAP  RPQMFGSMRP  SSQLPRMTSS  480
481   QRVDFSATQA  MGPRAATTAP  SVTANPVRGV  SQYKYATGVR  NTQQHVNAQP  QVTVQQPAVV  540
541   VQGQEPLTTS  MLAAAPLHEQ  KQMLGERLFP  LIQAMHLSLA  GKITGMLLEI  DNSELLHMLE  600
601   SPESLRSKVD  EAVAVLQAHQ  AKEAAQKSVT  NSAVVPSV  638
Nucleotide CDS Sequence (FASTA)
1     ATGAACCCCA  GTGCTGCCAG  TTACCCCATG  GCCTCCCTTT  ACGTCGGCGA  TCTCCATCCA  60
61    GATGTGACAG  AGGCCATGCT  GTACGAGAAA  TTCAGCCCGG  CCGGGGCGAT  CCTGTCTATC  120
121   CGGGTCTGTC  GGGACATGAT  CACCCGCCGA  TCCCTCGGAT  ACGCCTATGT  CAACTTCCAG  180
181   CAACCAGCCG  ACGCTGAGCG  TGCACTGGAC  ACCATGAACT  TTGATGTGAT  CAAGGGAAGA  240
241   CCCGTGCGAA  TCATGTGGTC  GCAGCGTGAT  CCATCATTGA  GGAAGAGCGG  CGTAGGAAAC  300
301   ATCTTCATCA  AAAACCTTGA  CAAGTCCATT  GACAACAAGG  CTCTGTATGA  CACGTTCTCT  360
361   GCTTTTGGAA  ACATCCTCTC  CTGCAAGGTG  GTTTGTGATG  AGAATGGCTC  TAAAGGCTAC  420
421   GGCTTTGTGC  ATTTTGAGAC  TCAGGAAGCA  GCCGAACGAG  CCATTGAAAA  AATGAATGGC  480
481   ATGTTGCTCA  ATGACCGAAA  AGTATTTGTT  GGACGCTTCA  AATCCCGCAA  GGAGCGCGAG  540
541   GCCGAACTCG  GGGCCCGCGC  CAGGGAGTTT  ACCAACGTTT  ACATTAAAAA  CTTTGGTGAC  600
601   GACATGGACG  AAGAGAAACT  GAGGGATGTT  TTTAACAAAT  ATGGAAATGC  CATGAGTATC  660
661   CGGGTCATGA  CCGATGACAG  CGGGAAGTCC  CGGGGCTTTG  GGTTTGTCAG  CTTTGAGAGA  720
721   CACGAGGACG  CCCAGAAGGC  TGTGGATGAG  ATGAATGGGA  AAGAGATGAA  TGGGAAACCC  780
781   ATTTACGTCG  GCCGCGCCCA  GAAGAAAGTG  GAGCGACAGG  CGGAGCTCAA  GCGCAAGTTT  840
841   GAGCAAATGA  AACAGGACCG  CATGACTCGC  TACCAGGGTG  TCAACCTGTA  TGTGAAGAAT  900
901   CTTGACGATG  GAATCGACGA  CGAACGTTTA  CGAAAGGAGT  TCTCGCCTTT  TGGCACCATC  960
961   ACCAGTGCCA  AGGTCATGCT  GGAAGGCGGT  CGCAGCAAAG  GCTTCGGCTT  CGTCTGCTTC  1020
1021  TCCTCCCCGG  AGGAGGCCAC  CAAAGCCGTG  ACCGAGATGA  ACGGACGCAT  CGTGGCCACC  1080
1081  AAGCCGCTGT  ACGTCGCTCT  GGCCCAGCGC  AAAGAGGAGC  GCCAAGCACA  CCTGACCAAC  1140
1141  CAGTACATGC  AGCGGATGGC  CAGCGTGCGC  GCAGTGCCCA  ACCCCGTCAT  CAACCCCTAC  1200
1201  CAGCCGGCCC  CGCCCTCTGG  CTACTTCATG  ACCGCCATCC  CCCAGACCCA  GAACCGGGGC  1260
1261  GCTTACTACC  CGGCAGCTGG  GCAGATGGCT  CAGCTGCGCC  CGAGCCCCCG  CTGGCCCACC  1320
1321  CAGGGTGTCC  GGCCGCAACA  CTTCCAAAAC  ATGCAAAGTG  CCATGCGCTC  CTCGGCTCCA  1380
1381  CGCCCTCAGA  TGTTCGGCTC  CATGCGGCCT  TCCTCGCAGC  TGCCTCGCAT  GACATCCAGC  1440
1441  CAGCGTGTTG  ATTTCTCAGC  CACCCAAGCC  ATGGGTCCCC  GAGCAGCCAC  CACGGCTCCT  1500
1501  TCGGTAACAG  CCAATCCTGT  TCGGGGGGTC  TCCCAGTACA  AGTACGCCAC  AGGAGTACGG  1560
1561  AACACGCAGC  AGCACGTCAA  CGCGCAGCCG  CAGGTCACCG  TGCAGCAGCC  CGCTGTTGTC  1620
1621  GTTCAGGGAC  AGGAGCCGCT  GACCACCTCC  ATGTTGGCCG  CTGCGCCGCT  GCACGAACAG  1680
1681  AAGCAGATGC  TGGGCGAGCG  CCTCTTCCCC  CTCATCCAGG  CCATGCACCT  GAGCCTTGCG  1740
1741  GGAAAGATTA  CCGGCATGCT  GCTGGAGATC  GACAACTCGG  AGCTTCTCCA  CATGCTGGAG  1800
1801  TCGCCTGAGT  CGCTGCGCTC  AAAGGTGGAC  GAGGCGGTGG  CCGTGCTTCA  GGCCCACCAG  1860
1861  GCCAAGGAGG  CCGCCCAGAA  GTCTGTGACT  AACTCAGCCG  TCGTGCCAAG  CGTGTGA  1917

▼ KEYWORD

ID
Family
Coiled coil
Complete proteome
Cytoplasm
Reference proteome
Repeat
RNA-binding

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Molecular Function
RNA binding

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Tar-2199Takifugu rubripes97.960.01206
LLPS-Leo-1629Lepisosteus oculatus90.640.01115
LLPS-Xim-0002Xiphophorus maculatus90.60.01122
LLPS-Pof-3524Poecilia formosa90.440.01118
LLPS-Orn-0345Oreochromis niloticus90.280.01115
LLPS-Dar-0605Danio rerio90.130.01108
LLPS-Asm-0750Astyanax mexicanus90.130.01118
LLPS-Scf-2272Scleropages formosus89.810.01113
LLPS-Gaa-0760Gasterosteus aculeatus88.650.01099
LLPS-Ora-0485Ornithorhynchus anatinus87.640.01085
LLPS-Caj-1510Callithrix jacchus87.480.01080
LLPS-Aon-0587Aotus nancymaae87.480.01080
LLPS-Ict-0733Ictidomys tridecemlineatus87.440.01021
LLPS-Orc-0006Oryctolagus cuniculus87.320.01079
LLPS-Pat-0096Pan troglodytes87.320.01079
LLPS-Hos-0089Homo sapiens87.320.01079
LLPS-Fec-1517Felis catus87.320.01079
LLPS-Cas-1467Carlito syrichta87.320.01079
LLPS-Poa-0944Pongo abelii87.320.01079
LLPS-Caf-0758Canis familiaris87.320.01079
LLPS-Cea-2929Cercocebus atys87.320.01079
LLPS-Sus-1508Sus scrofa87.320.01079
LLPS-Maf-2154Macaca fascicularis87.320.01079
LLPS-Mum-2049Mus musculus87.320.01078
LLPS-Chs-0101Chlorocebus sabaeus87.320.01079
LLPS-Bot-0676Bos taurus87.320.01079
LLPS-Ran-0034Rattus norvegicus87.170.01077
LLPS-Dio-2109Dipodomys ordii87.170.01077
LLPS-Scm-0124Scophthalmus maximus86.760.01078
LLPS-Mod-1104Monodelphis domestica86.720.01059
LLPS-Gaga-1755Gallus gallus86.720.01073
LLPS-Tag-0703Taeniopygia guttata86.560.01070
LLPS-Cap-0845Cavia porcellus86.260.0 947
LLPS-Ova-2449Ovis aries86.260.0 948
LLPS-Fud-0539Fukomys damarensis86.240.0 946
LLPS-Pes-0507Pelodiscus sinensis86.230.01061
LLPS-Aim-2318Ailuropoda melanoleuca86.230.01068
LLPS-Mup-1309Mustela putorius furo85.910.0 940
LLPS-Anp-0205Anas platyrhynchos85.760.0 943
LLPS-Mam-1121Macaca mulatta85.710.01072
LLPS-Paa-0853Papio anubis85.710.01072
LLPS-Loa-0207Loxodonta africana85.670.01061
LLPS-Orl-1335Oryzias latipes85.670.01065
LLPS-Fia-1800Ficedula albicollis85.590.0 941
LLPS-Meg-2928Meleagris gallopavo85.590.0 940
LLPS-Icp-1763Ictalurus punctatus85.130.01063
LLPS-Ere-0058Erinaceus europaeus84.990.0 914
LLPS-Sah-0552Sarcophilus harrisii84.350.01034
LLPS-Eqc-0520Equus caballus84.040.01065
LLPS-Urm-2358Ursus maritimus83.880.0 925
LLPS-Lac-0490Latimeria chalumnae83.730.01075
LLPS-Mea-0928Mesocricetus auratus83.280.01009
LLPS-Nol-1581Nomascus leucogenys83.10.01003
LLPS-Rhb-2848Rhinopithecus bieti82.940.0 988
LLPS-Tut-0106Tursiops truncatus82.870.01044
LLPS-Xet-1894Xenopus tropicalis82.650.01040
LLPS-Myl-1626Myotis lucifugus82.630.0 991
LLPS-Anc-0362Anolis carolinensis82.40.01058
LLPS-Man-3910Macaca nemestrina81.070.0 975
LLPS-Gog-2981Gorilla gorilla79.970.0 972
LLPS-Mal-0898Mandrillus leucophaeus79.840.0 953
LLPS-Otg-0780Otolemur garnettii79.560.0 954
LLPS-Pap-2020Pan paniscus72.840.0 897
LLPS-Scj-1180Schizosaccharomyces japonicus63.131e-162 487
LLPS-Cis-0525Ciona savignyi62.890.0 712
LLPS-Abg-1593Absidia glauca56.731e-165 492
LLPS-Drm-0098Drosophila melanogaster55.50.0 657
LLPS-Cae-0017Caenorhabditis elegans54.470.0 606
LLPS-Crn-0202Cryptococcus neoformans49.443e-177 527
LLPS-Scp-0021Schizosaccharomyces pombe48.280.0 542
LLPS-Pug-0751Puccinia graminis48.022e-180 539
LLPS-Chc-0157Chondrus crispus47.963e-180 534
LLPS-Sob-0152Sorghum bicolor46.512e-171 511
LLPS-Sei-0885Setaria italica46.52e-171 511
LLPS-Coc-0089Corchorus capsularis46.249e-169 504
LLPS-Orm-0242Oryza meridionalis46.148e-163 489
LLPS-Spr-0278Sporisorium reilianum46.092e-167 501
LLPS-Zem-1330Zea mays46.032e-168 503
LLPS-Org-0518Oryza glaberrima45.982e-162 488
LLPS-Orb-0262Oryza barthii45.982e-162 488
LLPS-Orgl-1206Oryza glumaepatula45.984e-162 487
LLPS-Hea-2274Helianthus annuus45.951e-162 488
LLPS-Gor-0295Gossypium raimondii45.921e-164 494
LLPS-Brd-0047Brachypodium distachyon45.858e-169 504
LLPS-Ors-1964Oryza sativa45.836e-162 487
LLPS-Orr-0393Oryza rufipogon45.836e-162 487
LLPS-Orni-0813Oryza nivara45.836e-162 487
LLPS-Thc-2063Theobroma cacao45.767e-163 489
LLPS-Orp-0276Oryza punctata45.677e-162 486
LLPS-Fuv-0450Fusarium verticillioides45.459e-168 505
LLPS-Kop-1053Komagataella pastoris45.414e-169 504
LLPS-Bro-0744Brassica oleracea45.385e-166 496
LLPS-Brn-1424Brassica napus45.385e-166 496
LLPS-Fuo-0124Fusarium oxysporum45.311e-167 504
LLPS-Tra-1166Triticum aestivum45.315e-164 492
LLPS-Brr-0456Brassica rapa45.116e-165 494
LLPS-Ori-0250Oryza indica44.941e-161 486
LLPS-Nec-1339Neurospora crassa44.741e-170 513
LLPS-Hov-0058Hordeum vulgare44.641e-161 488
LLPS-Blg-0163Blumeria graminis44.621e-169 511
LLPS-Prp-0523Prunus persica44.391e-166 499
LLPS-Dac-1191Daucus carota44.292e-161 485