• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Prp-1274
PRUPE_5G066800

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Phosphatidylserine decarboxylase proenzyme 1, mitochondrial
Gene Name: PRUPE_5G066800, PRUPE_ppa005808mg
Ensembl Gene: PRUPE_5G066800
Ensembl Protein: ONI06533
Organism: Prunus persica
Taxa ID: 3760
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Stress granulePredicted from orthologs(View)

▼ FUNCTION

Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MKFRASHRVC  IFSHSTHLNS  LHNQRRCFAS  FLKKLHKTPQ  ARSFSNGGGG  GSKGDSFLLP  60
61    GATVATLLML  GALHVRRMYD  DRKVEEALEK  GTEFEFQPDV  KSTFLRLLPL  RSISRCWGLL  120
121   TSVEIPVSLR  PYVYGAWARA  FHSNLEEAAL  PLDEYTSLRE  FFVRTLKEGS  RPIDPDPRCL  180
181   VSPVDGTVLR  FGELRGAGAM  IEQVKGFSYS  VFSLLGASSF  LPLIAKGDVH  EESSEPENAS  240
241   REKSKKSWLR  VSLASPKVWD  PVSTCPIKGL  FYCVIYLKPG  DYHRIHAPAD  WNVLVRRHFS  300
301   GRLLPVNERA  TRTIRNLYVE  NERVVLEGLW  KEGFMALAAV  GATNIGSIEL  SIEPELRTNQ  360
361   ARKKLLHSEP  PEERIYEPDG  IGRTLKKGDE  VAAFNMGSTV  VLVFQAPISL  SQENGDSASE  420
421   FRFSVQRGDR  VRVGEALGRW  RDQ  443
Nucleotide CDS Sequence (FASTA)
1     ATGAAGTTTA  GGGCTTCACA  TAGAGTCTGT  ATATTCTCTC  ACTCTACACA  CCTCAATTCC  60
61    CTCCATAACC  AGCGACGATG  CTTCGCTTCA  TTTCTTAAAA  AACTCCATAA  AACCCCTCAA  120
121   GCTCGCTCCT  TTTCCAATGG  CGGAGGTGGT  GGTTCTAAAG  GTGATTCTTT  TCTCTTGCCT  180
181   GGTGCAACGG  TGGCTACTTT  GCTTATGCTT  GGTGCTCTGC  ATGTTCGTCG  GATGTATGAT  240
241   GACAGGAAGG  TTGAGGAGGC  ACTGGAGAAG  GGAACGGAAT  TTGAATTTCA  ACCTGATGTA  300
301   AAATCTACAT  TTTTAAGATT  GCTGCCTTTG  CGCTCCATTT  CCAGATGTTG  GGGTTTATTG  360
361   ACCAGTGTGG  AAATCCCAGT  CTCTCTACGT  CCGTATGTTT  ATGGAGCGTG  GGCTCGAGCA  420
421   TTCCATTCAA  ACTTGGAAGA  AGCAGCTCTC  CCTCTGGATG  AATACACATC  TTTACGAGAG  480
481   TTCTTTGTTC  GCACCTTGAA  AGAAGGTTCC  AGGCCTATTG  ACCCTGACCC  ACGATGTCTG  540
541   GTTAGTCCTG  TGGATGGTAC  TGTATTACGA  TTTGGGGAGC  TTAGAGGAGC  AGGGGCTATG  600
601   ATTGAGCAAG  TCAAAGGTTT  TTCTTATTCA  GTTTTTTCCC  TGCTCGGTGC  AAGCTCATTT  660
661   CTTCCTTTGA  TAGCTAAAGG  AGATGTGCAT  GAGGAGAGTA  GTGAACCAGA  AAATGCTTCC  720
721   AGGGAGAAGA  GTAAGAAGTC  ATGGCTGAGA  GTTTCATTGG  CTTCTCCTAA  AGTTTGGGAC  780
781   CCTGTATCAA  CATGTCCTAT  AAAAGGCCTC  TTTTATTGTG  TAATTTACTT  GAAGCCTGGA  840
841   GACTATCATC  GCATACATGC  ACCAGCTGAT  TGGAATGTTC  TTGTCCGCCG  TCATTTTTCT  900
901   GGTCGTCTGC  TTCCTGTAAA  TGAACGTGCT  ACAAGAACTA  TCAGAAACCT  ATATGTTGAG  960
961   AACGAACGGG  TTGTGCTTGA  AGGTTTATGG  AAAGAAGGAT  TTATGGCACT  TGCTGCTGTT  1020
1021  GGAGCAACGA  ATATTGGTTC  AATTGAGCTT  TCCATTGAAC  CGGAACTTCG  GACAAACCAG  1080
1081  GCAAGAAAGA  AGTTACTGCA  CTCAGAGCCT  CCAGAAGAAC  GGATATATGA  ACCTGATGGT  1140
1141  ATTGGTAGGA  CGCTCAAGAA  AGGAGATGAG  GTAGCTGCAT  TCAACATGGG  ATCAACTGTT  1200
1201  GTGCTTGTCT  TCCAGGCTCC  CATATCACTA  TCACAAGAAA  ATGGGGATTC  CGCATCAGAG  1260
1261  TTCAGGTTTT  CGGTCCAACG  TGGGGATAGA  GTCCGTGTCG  GGGAAGCCTT  AGGGAGGTGG  1320
1321  CGGGATCAGT  AG  1332

▼ KEYWORD

ID
Family
Complete proteome
Decarboxylase
Lipid biosynthesis
Lipid metabolism
Lyase
Membrane
Mitochondrion
Mitochondrion inner membrane
Phospholipid biosynthesis
Phospholipid metabolism
Pyruvate
Reference proteome
Transmembrane
Transmembrane helix
Zymogen

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Integral component of mitochondrial inner membrane
Molecular Function
Phosphatidylserine decarboxylase activity
Biological Process
Phosphatidylethanolamine biosynthetic process
Biological Process
Protein autoprocessing

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Glm-0650Glycine max73.70.0 637
LLPS-Mae-1476Manihot esculenta73.650.0 661
LLPS-Via-2403Vigna angularis73.640.0 639
LLPS-Pot-1272Populus trichocarpa73.140.0 637
LLPS-Viv-0586Vitis vinifera72.170.0 629
LLPS-Phv-2286Phaseolus vulgaris72.143e-161 465
LLPS-Met-1918Medicago truncatula72.050.0 641
LLPS-Nia-2631Nicotiana attenuata71.762e-145 432
LLPS-Gor-0984Gossypium raimondii71.690.0 633
LLPS-Cus-2086Cucumis sativus70.790.0 634
LLPS-Thc-1686Theobroma cacao70.780.0 627
LLPS-Dac-1342Daucus carota70.470.0 617
LLPS-Sol-0530Solanum lycopersicum67.950.0 576
LLPS-Sot-0833Solanum tuberosum67.710.0 579
LLPS-Hea-0195Helianthus annuus66.220.0 580
LLPS-Brd-2298Brachypodium distachyon66.062e-176 508
LLPS-Orbr-0589Oryza brachyantha65.970.0 523
LLPS-Hov-1684Hordeum vulgare65.890.0 530
LLPS-Art-1947Arabidopsis thaliana65.210.0 585
LLPS-Brn-2306Brassica napus65.030.0 573
LLPS-Mua-2368Musa acuminata65.031e-179 515
LLPS-Orp-1654Oryza punctata64.950.0 523
LLPS-Sei-1830Setaria italica64.877e-174 502
LLPS-Bro-0182Brassica oleracea64.810.0 572
LLPS-Brr-2274Brassica rapa64.730.0 573
LLPS-Ors-1813Oryza sativa64.710.0 522
LLPS-Org-0710Oryza glaberrima64.710.0 522
LLPS-Ori-1898Oryza indica64.710.0 522
LLPS-Arl-2694Arabidopsis lyrata64.620.0 577
LLPS-Tra-0881Triticum aestivum64.580.0 520
LLPS-Orb-0696Oryza barthii63.719e-163 479
LLPS-Tru-2041Triticum urartu62.53e-153 485
LLPS-Amt-1973Amborella trichopoda59.870.0 540
LLPS-Orr-0104Oryza rufipogon57.662e-160 469
LLPS-Orgl-1646Oryza glumaepatula57.666e-160 468
LLPS-Lep-0410Leersia perrieri57.284e-150 441
LLPS-Php-0507Physcomitrella patens54.815e-138 410
LLPS-Vir-1900Vigna radiata53.184e-132 392
LLPS-Sem-2243Selaginella moellendorffii49.742e-123 370
LLPS-Spr-1574Sporisorium reilianum46.216e-23 105
LLPS-Usm-1434Ustilago maydis45.452e-22 104
LLPS-Tar-3684Takifugu rubripes41.532e-1784.7
LLPS-Anc-0251Anolis carolinensis41.451e-1784.7
LLPS-Dos-1144Dothistroma septosporum41.382e-1891.7
LLPS-Drm-1921Drosophila melanogaster41.092e-70 236
LLPS-Orn-0221Oreochromis niloticus39.944e-64 217
LLPS-Cii-1309Ciona intestinalis39.294e-59 205
LLPS-Scm-1463Scophthalmus maximus38.947e-1473.9
LLPS-Hos-4056Homo sapiens38.819e-60 207
LLPS-Tut-2297Tursiops truncatus38.744e-60 208
LLPS-Aim-3256Ailuropoda melanoleuca38.552e-60 209
LLPS-Man-4433Macaca nemestrina38.516e-61 210
LLPS-Pap-3116Pan paniscus38.516e-60 207
LLPS-Pat-1873Pan troglodytes38.516e-60 207
LLPS-Rhb-2623Rhinopithecus bieti38.518e-61 209
LLPS-Mam-1894Macaca mulatta38.516e-61 210
LLPS-Aon-1582Aotus nancymaae38.514e-60 208
LLPS-Cea-2577Cercocebus atys38.516e-61 210
LLPS-Chs-1613Chlorocebus sabaeus38.516e-61 210
LLPS-Maf-1246Macaca fascicularis38.516e-61 210
LLPS-Gog-2690Gorilla gorilla38.516e-60 207
LLPS-Mal-3234Mandrillus leucophaeus38.514e-61 210
LLPS-Orl-4096Oryzias latipes38.487e-62 212
LLPS-Pof-2277Poecilia formosa38.441e-65 221
LLPS-Cis-2041Ciona savignyi38.363e-54 189
LLPS-Xim-1482Xiphophorus maculatus38.352e-62 215
LLPS-Scc-0198Schizosaccharomyces cryophilus38.214e-63 216
LLPS-Gaa-3464Gasterosteus aculeatus38.181e-60 208
LLPS-Dar-1854Danio rerio38.145e-67 226
LLPS-Scp-1541Schizosaccharomyces pombe38.043e-64 219
LLPS-Lac-2857Latimeria chalumnae38.022e-59 210
LLPS-Abg-0870Absidia glauca37.994e-62 215
LLPS-Mod-4155Monodelphis domestica37.983e-62 214
LLPS-Paa-3921Papio anubis37.877e-61 210
LLPS-Scf-3146Scleropages formosus37.851e-65 221
LLPS-Leo-1839Lepisosteus oculatus37.681e-64 219
LLPS-Anp-2220Anas platyrhynchos37.64e-63 216
LLPS-Ten-2217Tetraodon nigroviridis37.59e-60 205
LLPS-Asm-3205Astyanax mexicanus37.464e-64 219
LLPS-Xet-1684Xenopus tropicalis37.396e-66 223
LLPS-Fuo-0455Fusarium oxysporum37.348e-66 226
LLPS-Fuv-0270Fusarium verticillioides37.341e-65 226
LLPS-Put-0489Puccinia triticina37.214e-56 195
LLPS-Pug-1090Puccinia graminis37.21e-62 215
LLPS-Fud-3645Fukomys damarensis37.044e-60 207
LLPS-Tag-2618Taeniopygia guttata36.991e-66 224
LLPS-Gaga-3089Gallus gallus36.992e-64 219
LLPS-Scj-1475Schizosaccharomyces japonicus36.993e-62 214
LLPS-Orc-0596Oryctolagus cuniculus36.832e-59 206
LLPS-Fia-0834Ficedula albicollis36.834e-62 213
LLPS-Mel-0754Melampsora laricipopulina36.832e-56 198
LLPS-Mup-3379Mustela putorius furo36.833e-61 209
LLPS-Ora-2313Ornithorhynchus anatinus36.817e-62 211
LLPS-Tum-1328Tuber melanosporum36.691e-56 197
LLPS-Icp-0151Ictalurus punctatus36.638e-66 223
LLPS-Cap-1816Cavia porcellus36.541e-60 209
LLPS-Sus-4646Sus scrofa36.496e-60 207
LLPS-Caj-3700Callithrix jacchus36.496e-60 207
LLPS-Myl-2408Myotis lucifugus36.443e-61 211
LLPS-Fus-1426Fusarium solani36.365e-61 213
LLPS-Ved-0993Verticillium dahliae36.33e-64 222
LLPS-Dio-1745Dipodomys ordii36.271e-58 207
LLPS-Trv-1426Trichoderma virens36.141e-63 219
LLPS-Miv-1493Microbotryum violaceum36.114e-55 199
LLPS-Poa-1890Pongo abelii36.031e-59 207
LLPS-Sac-0203Saccharomyces cerevisiae36.09e-63 217
LLPS-Ict-3372Ictidomys tridecemlineatus35.97e-61 210
LLPS-Cas-3654Carlito syrichta35.892e-59 206
LLPS-Trr-1603Trichoderma reesei35.823e-64 221
LLPS-Ova-0369Ovis aries35.822e-48 177
LLPS-Mum-4884Mus musculus35.799e-59 204
LLPS-Cogr-1501Colletotrichum graminicola35.667e-63 218
LLPS-Pes-3056Pelodiscus sinensis35.549e-59 203
LLPS-Loa-4192Loxodonta africana35.534e-49 177
LLPS-Nec-1365Neurospora crassa35.416e-63 218
LLPS-Crn-1104Cryptococcus neoformans35.352e-56 201
LLPS-Ran-2115Rattus norvegicus35.254e-56 197
LLPS-Gag-0929Gaeumannomyces graminis35.242e-59 209
LLPS-Pyt-0084Pyrenophora teres35.11e-62 218
LLPS-Coo-1437Colletotrichum orbiculare35.072e-59 208
LLPS-Pytr-0012Pyrenophora triticirepentis34.862e-62 214
LLPS-Yal-1486Yarrowia lipolytica34.683e-58 206
LLPS-Cog-1075Colletotrichum gloeosporioides34.654e-54 193
LLPS-Phn-1492Phaeosphaeria nodorum34.641e-61 212
LLPS-Fec-1834Felis catus34.524e-62 213
LLPS-Asg-1337Ashbya gossypii34.371e-58 206
LLPS-Caf-2049Canis familiaris34.283e-61 211
LLPS-Kop-1476Komagataella pastoris34.162e-55 199
LLPS-Scs-0721Sclerotinia sclerotiorum34.03e-56 198
LLPS-Ast-1212Aspergillus terreus33.834e-58 206
LLPS-Asfu-1428Aspergillus fumigatus33.668e-57 202
LLPS-Eqc-3732Equus caballus33.655e-59 205
LLPS-Nef-1004Neosartorya fischeri33.423e-56 201
LLPS-Cae-1950Caenorhabditis elegans33.334e-49 177
LLPS-Asni-0498Aspergillus niger33.333e-58 206
LLPS-Aso-1519Aspergillus oryzae33.098e-56 199
LLPS-Asf-1540Aspergillus flavus33.098e-56 199
LLPS-Otg-4405Otolemur garnettii33.047e-60 207
LLPS-Blg-1023Blumeria graminis32.853e-52 189
LLPS-Sah-2136Sarcophilus harrisii32.842e-1684.7
LLPS-Map-0987Magnaporthe poae32.821e-47 175
LLPS-Zyt-1185Zymoseptoria tritici32.772e-53 193
LLPS-Asn-1316Aspergillus nidulans32.674e-54 195
LLPS-Cym-1084Cyanidioschyzon merolae32.662e-42 159
LLPS-Mao-1381Magnaporthe oryzae32.241e-57 204
LLPS-Chc-1203Chondrus crispus31.871e-36 143
LLPS-Asc-0338Aspergillus clavatus31.614e-55 197
LLPS-Beb-0396Beauveria bassiana28.772e-35 141