• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Pes-1643

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: GTP-binding nuclear protein Ran
Ensembl Gene: ENSPSIG00000002376.1
Ensembl Protein: ENSPSIP00000002413.1
Organism: Pelodiscus sinensis
Taxa ID: 13735
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Centrosome/Spindle pole body, P-body, Stress granule, OthersPredicted from orthologs(View)

▼ FUNCTION

GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAAQGEPQVQ  FKLVLVGDGG  TGKTTFVKRH  LTGEFEKKYV  ATLGVEVHPL  VFHTNRGPIK  60
61    FNVWDTAGQE  KFGGLRDGYY  IQAQCAIIMF  DVTSRVTYKN  VPNWHRDLVR  VCENIPIVLC  120
121   GNKVDIKDRK  VKAKSIVFHR  KKNLQYYDIS  AKSNYNFEKP  FLWLARKLIG  DPNLEFVAMP  180
181   ALAPPEVVMD  PALAAQYEQD  LQIAQTTALP  DEDDDL  216
Nucleotide CDS Sequence (FASTA)
1     ATGGCCGCCC  AAGGAGAGCC  CCAAGTACAG  TTTAAGCTTG  TCTTGGTTGG  TGATGGTGGT  60
61    ACTGGTAAAA  CGACGTTTGT  AAAACGTCAT  TTGACTGGTG  AATTTGAAAA  GAAGTATGTA  120
121   GCTACATTGG  GTGTTGAAGT  CCATCCTCTG  GTGTTCCACA  CTAATAGAGG  TCCTATTAAA  180
181   TTTAATGTAT  GGGACACGGC  TGGTCAGGAG  AAATTTGGTG  GTTTGCGGGA  TGGATACTAT  240
241   ATCCAAGCTC  AGTGTGCCAT  CATCATGTTT  GATGTAACAT  CAAGAGTTAC  ATACAAGAAT  300
301   GTACCTAACT  GGCATAGAGA  TCTAGTACGA  GTATGTGAAA  ACATCCCTAT  AGTGTTGTGT  360
361   GGCAACAAAG  TGGATATTAA  GGATAGAAAA  GTCAAGGCAA  AGTCAATTGT  CTTCCACAGG  420
421   AAGAAGAATC  TTCAGTACTA  TGATATCTCA  GCTAAGAGTA  ACTACAATTT  TGAGAAGCCT  480
481   TTCCTTTGGC  TTGCCAGGAA  GCTAATTGGC  GATCCCAACT  TGGAGTTCGT  TGCCATGCCT  540
541   GCTCTTGCTC  CCCCAGAGGT  TGTCATGGAC  CCTGCTTTGG  CAGCACAGTA  TGAGCAAGAC  600
601   TTACAGATTG  CTCAGACCAC  TGCCCTGCCA  GATGAAGATG  ATGACCTGTA  A  651

▼ KEYWORD

ID
Family
Complete proteome
GTP-binding
Nucleotide-binding
Nucleus
Protein transport
Reference proteome
Transport

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Nucleus
Molecular Function
GTP binding
Molecular Function
GTPase activity
Biological Process
Nucleocytoplasmic transport
Biological Process
Protein transport

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Anp-1731Anas platyrhynchos100.07e-161 451
LLPS-Mod-0590Monodelphis domestica100.07e-161 451
LLPS-Fia-1549Ficedula albicollis100.07e-161 451
LLPS-Tag-1283Taeniopygia guttata100.05e-161 451
LLPS-Gaga-0464Gallus gallus100.07e-161 451
LLPS-Ora-0624Ornithorhynchus anatinus100.01e-161 453
LLPS-Anc-0579Anolis carolinensis99.534e-159 446
LLPS-Sah-0098Sarcophilus harrisii99.073e-159 446
LLPS-Loa-0259Loxodonta africana98.612e-159 447
LLPS-Otg-1159Otolemur garnettii98.612e-159 447
LLPS-Eqc-0121Equus caballus98.611e-158 449
LLPS-Poa-0338Pongo abelii98.611e-159 448
LLPS-Nol-1720Nomascus leucogenys98.612e-159 447
LLPS-Sus-3093Sus scrofa98.612e-159 447
LLPS-Mum-0705Mus musculus98.612e-159 447
LLPS-Bot-3475Bos taurus98.612e-159 447
LLPS-Tut-0355Tursiops truncatus98.612e-159 447
LLPS-Ova-1077Ovis aries98.612e-159 447
LLPS-Paa-1461Papio anubis98.612e-159 447
LLPS-Ran-0351Rattus norvegicus98.612e-159 447
LLPS-Caf-1791Canis familiaris98.531e-149 422
LLPS-Ict-1214Ictidomys tridecemlineatus98.535e-150 423
LLPS-Xet-0648Xenopus tropicalis98.174e-157 441
LLPS-Meg-0288Meleagris gallopavo98.13e-153 431
LLPS-Fec-0798Felis catus98.063e-150 424
LLPS-Fud-0562Fukomys damarensis98.051e-149 422
LLPS-Urm-1096Ursus maritimus97.662e-88 264
LLPS-Leo-0063Lepisosteus oculatus97.221e-157 442
LLPS-Chs-0659Chlorocebus sabaeus96.692e-104 305
LLPS-Mup-0142Mustela putorius furo96.652e-149 422
LLPS-Lac-1951Latimeria chalumnae96.482e-97 287
LLPS-Dio-0913Dipodomys ordii96.32e-92 275
LLPS-Pap-4706Pan paniscus95.855e-153 431
LLPS-Mea-2578Mesocricetus auratus95.832e-155 437
LLPS-Scf-1096Scleropages formosus95.791e-153 432
LLPS-Man-1215Macaca nemestrina94.911e-150 426
LLPS-Hos-1106Homo sapiens94.911e-150 426
LLPS-Pat-2094Pan troglodytes94.911e-150 426
LLPS-Cea-2779Cercocebus atys94.911e-150 426
LLPS-Caj-0615Callithrix jacchus94.913e-150 426
LLPS-Aim-1266Ailuropoda melanoleuca94.886e-151 426
LLPS-Orc-1874Oryctolagus cuniculus93.941e-113 329
LLPS-Dar-1633Danio rerio93.934e-151 426
LLPS-Scm-0088Scophthalmus maximus93.692e-145 412
LLPS-Asm-0598Astyanax mexicanus93.468e-151 425
LLPS-Tar-0495Takifugu rubripes92.525e-147 416
LLPS-Cii-0020Ciona intestinalis92.05e-99 291
LLPS-Cae-0207Caenorhabditis elegans91.755e-133 380
LLPS-Pof-1043Poecilia formosa91.593e-147 417
LLPS-Orn-1179Oreochromis niloticus91.591e-146 414
LLPS-Orl-1353Oryzias latipes91.593e-147 416
LLPS-Gaa-1991Gasterosteus aculeatus91.591e-146 414
LLPS-Xim-2383Xiphophorus maculatus91.599e-147 415
LLPS-Mam-0488Macaca mulatta91.422e-155 437
LLPS-Maf-0453Macaca fascicularis91.422e-155 437
LLPS-Ten-0261Tetraodon nigroviridis91.124e-145 411
LLPS-Rhb-0198Rhinopithecus bieti90.991e-154 436
LLPS-Aon-0884Aotus nancymaae90.238e-142 402
LLPS-Drm-1290Drosophila melanogaster87.54e-140 398
LLPS-Cas-3332Carlito syrichta87.321e-126 363
LLPS-Icp-1602Ictalurus punctatus85.154e-140 399
LLPS-Gog-0048Gorilla gorilla84.163e-120 347
LLPS-Gas-0209Galdieria sulphuraria83.52e-127 366
LLPS-Asg-0324Ashbya gossypii83.334e-127 365
LLPS-Asni-0642Aspergillus niger82.846e-127 364
LLPS-Zyt-0072Zymoseptoria tritici82.352e-125 361
LLPS-Scj-0424Schizosaccharomyces japonicus82.244e-127 365
LLPS-Lem-0679Leptosphaeria maculans82.162e-126 363
LLPS-Sac-0082Saccharomyces cerevisiae82.169e-128 367
LLPS-Scp-0426Schizosaccharomyces pombe82.082e-126 363
LLPS-Kop-1019Komagataella pastoris81.861e-122 353
LLPS-Scc-0453Schizosaccharomyces cryophilus81.789e-127 364
LLPS-Trr-0331Trichoderma reesei81.732e-116 338
LLPS-Beb-0853Beauveria bassiana81.198e-121 349
LLPS-Mal-1042Mandrillus leucophaeus80.953e-106 310
LLPS-Put-0150Puccinia triticina80.883e-118 342
LLPS-Tum-0025Tuber melanosporum80.887e-123 354
LLPS-Aso-0315Aspergillus oryzae80.844e-126 362
LLPS-Asf-0348Aspergillus flavus80.778e-117 339
LLPS-Pug-0651Puccinia graminis80.393e-117 340
LLPS-Spr-0530Sporisorium reilianum80.379e-121 349
LLPS-Usm-0386Ustilago maydis80.372e-116 338
LLPS-Abg-0716Absidia glauca80.375e-122 352
LLPS-Ors-0649Oryza sativa80.212e-108 318
LLPS-Orbr-0020Oryza brachyantha80.212e-108 318
LLPS-Ori-0631Oryza indica80.212e-108 318
LLPS-Sei-2266Setaria italica80.213e-109 320
LLPS-Phn-0266Phaeosphaeria nodorum80.163e-70 217
LLPS-Map-0086Magnaporthe poae80.091e-116 338
LLPS-Nec-0290Neurospora crassa80.02e-114 333
LLPS-Asfu-0631Aspergillus fumigatus79.913e-127 365
LLPS-Asn-0461Aspergillus nidulans79.912e-125 360
LLPS-Pyt-1144Pyrenophora teres79.912e-125 361
LLPS-Miv-1044Microbotryum violaceum79.92e-120 348
LLPS-Crn-1068Cryptococcus neoformans79.92e-125 360
LLPS-Mel-0718Melampsora laricipopulina79.93e-120 348
LLPS-Orni-1566Oryza nivara79.791e-102 320
LLPS-Dos-0253Dothistroma septosporum79.729e-125 359
LLPS-Blg-0743Blumeria graminis79.725e-117 339
LLPS-Orp-0335Oryza punctata79.683e-108 317
LLPS-Sob-2059Sorghum bicolor79.684e-108 317
LLPS-Zem-0744Zea mays79.684e-108 317
LLPS-Org-0569Oryza glaberrima79.681e-108 318
LLPS-Orb-0368Oryza barthii79.681e-108 318
LLPS-Orgl-0598Oryza glumaepatula79.681e-108 318
LLPS-Tra-0810Triticum aestivum79.681e-108 318
LLPS-Orm-1802Oryza meridionalis79.472e-108 319
LLPS-Orr-1637Oryza rufipogon79.478e-108 319
LLPS-Trv-0082Trichoderma virens79.368e-117 339
LLPS-Brd-0086Brachypodium distachyon79.142e-108 317
LLPS-Yal-0211Yarrowia lipolytica78.922e-118 343
LLPS-Cogr-1051Colletotrichum graminicola78.93e-115 335
LLPS-Mao-0368Magnaporthe oryzae78.874e-116 337
LLPS-Cog-0062Colletotrichum gloeosporioides78.84e-115 335
LLPS-Tru-1110Triticum urartu78.761e-110 322
LLPS-Mae-0647Manihot esculenta78.541e-118 343
LLPS-Coc-0074Corchorus capsularis78.544e-118 342
LLPS-Mua-0299Musa acuminata78.58e-111 325
LLPS-Cym-0368Cyanidioschyzon merolae78.51e-121 352
LLPS-Fus-0442Fusarium solani78.442e-115 335
LLPS-Fuo-0579Fusarium oxysporum78.442e-115 335
LLPS-Fuv-0320Fusarium verticillioides78.442e-115 335
LLPS-Art-1567Arabidopsis thaliana78.057e-110 322
LLPS-Viv-1397Vitis vinifera78.053e-117 340
LLPS-Phv-0377Phaseolus vulgaris78.053e-117 340
LLPS-Prp-0588Prunus persica78.053e-117 340
LLPS-Php-0036Physcomitrella patens78.056e-116 337
LLPS-Hea-0801Helianthus annuus78.052e-117 341
LLPS-Sot-0336Solanum tuberosum78.057e-116 337
LLPS-Via-0822Vigna angularis78.053e-117 340
LLPS-Arl-2721Arabidopsis lyrata78.057e-110 322
LLPS-Met-0210Medicago truncatula78.056e-117 339
LLPS-Scs-0133Sclerotinia sclerotiorum78.045e-116 337
LLPS-Asc-0985Aspergillus clavatus78.045e-120 347
LLPS-Ved-0381Verticillium dahliae77.984e-116 337
LLPS-Gor-0787Gossypium raimondii77.676e-117 340
LLPS-Brr-1559Brassica rapa77.563e-117 340
LLPS-Bro-1701Brassica oleracea77.563e-117 340
LLPS-Brn-1596Brassica napus77.561e-117 342
LLPS-Sol-1594Solanum lycopersicum77.562e-115 335
LLPS-Glm-1374Glycine max77.566e-117 339
LLPS-Thc-0090Theobroma cacao77.564e-116 337
LLPS-Cus-0588Cucumis sativus77.563e-116 338
LLPS-Pot-0850Populus trichocarpa77.182e-116 338
LLPS-Nef-0924Neosartorya fischeri76.642e-118 342
LLPS-Pytr-0928Pyrenophora triticirepentis76.642e-117 340
LLPS-Gag-0249Gaeumannomyces graminis75.786e-111 325
LLPS-Chc-0490Chondrus crispus75.71e-110 323
LLPS-Dac-1610Daucus carota75.681e-79 243
LLPS-Chr-0021Chlamydomonas reinhardtii75.121e-110 323
LLPS-Hov-0100Hordeum vulgare75.01e-111 326
LLPS-Nia-0306Nicotiana attenuata74.776e-117 340
LLPS-Amt-1779Amborella trichopoda74.311e-112 328
LLPS-Sem-0902Selaginella moellendorffii74.076e-115 334
LLPS-Coo-0003Colletotrichum orbiculare74.032e-111 325
LLPS-Ast-0600Aspergillus terreus73.822e-121 351
LLPS-Osl-0319Ostreococcus lucimarinus73.731e-116 338
LLPS-Vir-0811Vigna radiata73.63e-106 311
LLPS-Lep-1218Leersia perrieri70.562e-107 315
LLPS-Cap-3073Cavia porcellus32.541e-27 110
LLPS-Myl-0690Myotis lucifugus32.541e-27 110