• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Dos-0253
DOTSEDRAFT_70514

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: GTP-binding nuclear protein
Gene Name: DOTSEDRAFT_70514
Ensembl Gene: DOTSEDRAFT_70514
Ensembl Protein: EME46530
Organism: Dothistroma septosporum
Taxa ID: 675120
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Centrosome/Spindle pole body, P-body, Stress granule, OthersPredicted from orthologs(View)

▼ FUNCTION

GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblEME46530EME46530
UniProtN1PVZ4, N1PVZ4_DOTSN
GeneBankKB446537EME46530.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAEGQQTPTF  KLVLVGDGGT  GKTTFVKRHL  TGEFEKKYIA  TLGVEVHPLG  FTTNLGQIQF  60
61    DVWDTAGQEK  FGGLRDGYYI  NGQCGIIMFD  VTSRITYKNV  PNWHRDLVRV  CENIPIVLTG  120
121   NKVDVKERKV  KAKTITFHRK  KNLQYYDISA  KSNYNFEKPF  LWLARKLVGN  QSLEFVAAPA  180
181   LAPPEVQVDQ  AAMEQYQKEM  QDAANMPLPD  EEDPDL  216
Nucleotide CDS Sequence (FASTA)
1     ATGGCGGAAG  GCCAGCAGAC  CCCAACCTTC  AAGCTCGTTC  TTGTTGGTGA  CGGTGGTACC  60
61    GGAAAGACCA  CCTTCGTGAA  GCGCCATTTG  ACGGGAGAGT  TCGAGAAGAA  GTACATCGCA  120
121   ACTCTCGGTG  TCGAAGTTCA  CCCGCTTGGT  TTCACTACCA  ACCTCGGCCA  GATCCAGTTC  180
181   GACGTGTGGG  ACACAGCAGG  TCAAGAGAAG  TTTGGTGGTC  TTCGTGATGG  ATACTACATC  240
241   AACGGCCAGT  GCGGTATCAT  CATGTTCGAT  GTCACTTCTC  GCATCACCTA  CAAGAACGTC  300
301   CCCAACTGGC  ACCGCGATCT  TGTCCGTGTG  TGTGAGAACA  TCCCGATTGT  TCTCACTGGC  360
361   AACAAAGTCG  ACGTGAAGGA  GCGCAAGGTC  AAGGCCAAGA  CCATCACCTT  CCACCGCAAG  420
421   AAGAACCTCC  AGTACTACGA  CATCTCGGCC  AAGTCCAACT  ACAACTTCGA  GAAGCCGTTC  480
481   CTGTGGCTCG  CACGAAAGCT  TGTCGGCAAC  CAGTCTCTGG  AATTCGTCGC  TGCCCCAGCT  540
541   CTCGCCCCAC  CGGAGGTCCA  GGTCGACCAG  GCCGCCATGG  AGCAGTACCA  GAAGGAGATG  600
601   CAAGACGCAG  CCAACATGCC  GCTGCCGGAC  GAGGAGGACC  CCGACTTGTA  A  651

▼ KEYWORD

ID
Family
Coiled coil
Complete proteome
GTP-binding
Nucleotide-binding
Nucleus
Protein transport
Reference proteome
Transport

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Nucleus
Molecular Function
GTP binding
Molecular Function
GTPase activity
Biological Process
Nucleocytoplasmic transport
Biological Process
Protein transport

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Zyt-0072Zymoseptoria tritici96.686e-152 428
LLPS-Phn-0266Phaeosphaeria nodorum94.575e-87 260
LLPS-Tru-1110Triticum urartu94.391e-135 386
LLPS-Lem-0679Leptosphaeria maculans93.125e-149 421
LLPS-Asfu-0631Aspergillus fumigatus91.95e-143 405
LLPS-Asn-0461Aspergillus nidulans91.675e-145 410
LLPS-Cogr-1051Colletotrichum graminicola91.512e-134 384
LLPS-Asni-0642Aspergillus niger91.473e-142 403
LLPS-Trv-0082Trichoderma virens91.242e-135 386
LLPS-Trr-0331Trichoderma reesei90.784e-136 388
LLPS-Cog-0062Colletotrichum gloeosporioides90.786e-137 390
LLPS-Pyt-1144Pyrenophora teres90.781e-146 414
LLPS-Scs-0133Sclerotinia sclerotiorum90.75e-137 390
LLPS-Asf-0348Aspergillus flavus90.434e-131 375
LLPS-Nec-0290Neurospora crassa90.433e-133 380
LLPS-Fus-0442Fusarium solani90.327e-134 382
LLPS-Fuo-0579Fusarium oxysporum90.327e-134 382
LLPS-Fuv-0320Fusarium verticillioides90.327e-134 382
LLPS-Aso-0315Aspergillus oryzae89.477e-139 395
LLPS-Beb-0853Beauveria bassiana88.485e-131 375
LLPS-Blg-0743Blumeria graminis88.433e-134 383
LLPS-Nef-0924Neosartorya fischeri88.13e-134 382
LLPS-Asc-0985Aspergillus clavatus87.968e-136 387
LLPS-Ved-0381Verticillium dahliae87.854e-132 378
LLPS-Pytr-0928Pyrenophora triticirepentis87.565e-139 395
LLPS-Asg-0324Ashbya gossypii87.22e-138 394
LLPS-Sac-0082Saccharomyces cerevisiae87.27e-138 392
LLPS-Scc-0453Schizosaccharomyces cryophilus86.793e-135 385
LLPS-Scj-0424Schizosaccharomyces japonicus86.793e-135 385
LLPS-Cii-0020Ciona intestinalis86.679e-95 281
LLPS-Tum-0025Tuber melanosporum86.572e-139 396
LLPS-Scp-0426Schizosaccharomyces pombe86.575e-137 390
LLPS-Lac-1951Latimeria chalumnae86.234e-85 256
LLPS-Map-0086Magnaporthe poae85.652e-126 363
LLPS-Mao-0368Magnaporthe oryzae85.652e-129 371
LLPS-Coo-0003Colletotrichum orbiculare85.283e-133 381
LLPS-Crn-1068Cryptococcus neoformans84.916e-134 382
LLPS-Kop-1019Komagataella pastoris84.691e-129 371
LLPS-Spr-0530Sporisorium reilianum84.654e-125 360
LLPS-Usm-0386Ustilago maydis84.195e-120 347
LLPS-Ast-0600Aspergillus terreus83.836e-140 398
LLPS-Cae-0207Caenorhabditis elegans83.336e-126 362
LLPS-Miv-1044Microbotryum violaceum83.259e-127 363
LLPS-Chs-0659Chlorocebus sabaeus82.996e-86 258
LLPS-Abg-0716Absidia glauca82.388e-127 364
LLPS-Put-0150Puccinia triticina81.942e-123 355
LLPS-Meg-0288Meleagris gallopavo81.771e-122 353
LLPS-Pug-0651Puccinia graminis81.483e-122 353
LLPS-Yal-0211Yarrowia lipolytica81.227e-128 367
LLPS-Caf-1791Canis familiaris81.193e-121 350
LLPS-Man-1215Macaca nemestrina80.888e-122 352
LLPS-Fec-0798Felis catus80.887e-122 352
LLPS-Hos-1106Homo sapiens80.888e-122 352
LLPS-Pat-2094Pan troglodytes80.888e-122 352
LLPS-Caj-0615Callithrix jacchus80.881e-121 353
LLPS-Cea-2779Cercocebus atys80.888e-122 352
LLPS-Paa-1177Papio anubis80.888e-122 352
LLPS-Mel-0718Melampsora laricipopulina80.563e-125 360
LLPS-Gag-0249Gaeumannomyces graminis80.532e-119 346
LLPS-Ict-1214Ictidomys tridecemlineatus80.494e-122 352
LLPS-Mup-0142Mustela putorius furo80.491e-120 348
LLPS-Sob-2059Sorghum bicolor80.422e-112 328
LLPS-Zem-0744Zea mays80.422e-112 328
LLPS-Fud-0562Fukomys damarensis80.11e-121 351
LLPS-Art-1567Arabidopsis thaliana79.94e-112 327
LLPS-Arl-2721Arabidopsis lyrata79.94e-112 327
LLPS-Orbr-0020Oryza brachyantha79.894e-110 322
LLPS-Ors-0649Oryza sativa79.894e-110 322
LLPS-Orni-1566Oryza nivara79.892e-104 324
LLPS-Ori-0631Oryza indica79.894e-110 322
LLPS-Sei-2266Setaria italica79.891e-110 323
LLPS-Gaa-1991Gasterosteus aculeatus79.811e-126 364
LLPS-Fia-1549Ficedula albicollis79.729e-125 359
LLPS-Pes-1643Pelodiscus sinensis79.729e-125 359
LLPS-Anp-1731Anas platyrhynchos79.729e-125 359
LLPS-Mod-0590Monodelphis domestica79.729e-125 359
LLPS-Pof-1043Poecilia formosa79.722e-125 361
LLPS-Tag-1283Taeniopygia guttata79.728e-125 359
LLPS-Gaga-0464Gallus gallus79.729e-125 359
LLPS-Ora-0624Ornithorhynchus anatinus79.727e-125 360
LLPS-Xim-2383Xiphophorus maculatus79.724e-125 360
LLPS-Anc-0579Anolis carolinensis79.624e-124 357
LLPS-Leo-0063Lepisosteus oculatus79.621e-124 358
LLPS-Xet-0648Xenopus tropicalis79.444e-123 355
LLPS-Tra-0810Triticum aestivum79.373e-109 320
LLPS-Scf-1096Scleropages formosus79.347e-126 362
LLPS-Otg-1159Otolemur garnettii79.256e-124 357
LLPS-Loa-0259Loxodonta africana79.256e-124 357
LLPS-Nol-1720Nomascus leucogenys79.256e-124 357
LLPS-Eqc-0121Equus caballus79.251e-122 358
LLPS-Poa-0338Pongo abelii79.255e-124 358
LLPS-Sus-3093Sus scrofa79.256e-124 357
LLPS-Orl-1353Oryzias latipes79.256e-124 357
LLPS-Mum-0705Mus musculus79.256e-124 357
LLPS-Ova-1077Ovis aries79.256e-124 357
LLPS-Ran-0351Rattus norvegicus79.256e-124 357
LLPS-Bot-3475Bos taurus79.256e-124 357
LLPS-Tut-0355Tursiops truncatus79.255e-124 358
LLPS-Gas-0209Galdieria sulphuraria79.152e-121 350
LLPS-Drm-1290Drosophila melanogaster79.155e-125 360
LLPS-Scm-0088Scophthalmus maximus79.071e-125 361
LLPS-Orp-0335Oryza punctata78.979e-112 326
LLPS-Orn-1179Oreochromis niloticus78.879e-126 362
LLPS-Pap-4706Pan paniscus78.871e-121 351
LLPS-Ten-0261Tetraodon nigroviridis78.878e-125 359
LLPS-Tar-0495Takifugu rubripes78.875e-125 360
LLPS-Brd-0086Brachypodium distachyon78.842e-109 320
LLPS-Sah-0098Sarcophilus harrisii78.774e-123 355
LLPS-Cus-0588Cucumis sativus78.642e-120 348
LLPS-Org-0569Oryza glaberrima78.461e-110 323
LLPS-Orm-1802Oryza meridionalis78.469e-111 325
LLPS-Orr-1637Oryza rufipogon78.463e-110 325
LLPS-Orb-0368Oryza barthii78.469e-111 323
LLPS-Orgl-0598Oryza glumaepatula78.469e-111 323
LLPS-Aim-1266Ailuropoda melanoleuca78.34e-121 350
LLPS-Mua-0299Musa acuminata77.881e-114 335
LLPS-Mae-0647Manihot esculenta77.832e-121 350
LLPS-Mea-0323Mesocricetus auratus77.833e-121 350
LLPS-Urm-1096Ursus maritimus77.782e-68 212
LLPS-Dar-1633Danio rerio77.464e-123 355
LLPS-Asm-0598Astyanax mexicanus77.465e-123 355
LLPS-Osl-0319Ostreococcus lucimarinus77.45e-122 352
LLPS-Met-0210Medicago truncatula77.366e-121 349
LLPS-Phv-0377Phaseolus vulgaris76.895e-120 347
LLPS-Coc-0074Corchorus capsularis76.893e-120 348
LLPS-Hea-0801Helianthus annuus76.892e-120 348
LLPS-Glm-0094Glycine max76.898e-119 347
LLPS-Sol-1594Solanum lycopersicum76.891e-119 346
LLPS-Sot-1646Solanum tuberosum76.891e-119 346
LLPS-Via-0822Vigna angularis76.895e-120 347
LLPS-Amt-1779Amborella trichopoda76.71e-114 333
LLPS-Nia-0306Nicotiana attenuata76.532e-120 349
LLPS-Cym-0368Cyanidioschyzon merolae76.534e-119 345
LLPS-Brr-1559Brassica rapa76.424e-120 347
LLPS-Gor-0787Gossypium raimondii76.423e-119 346
LLPS-Viv-1397Vitis vinifera76.422e-119 346
LLPS-Bro-1701Brassica oleracea76.424e-120 347
LLPS-Prp-0588Prunus persica76.422e-119 345
LLPS-Thc-0090Theobroma cacao76.421e-119 346
LLPS-Brn-1596Brassica napus76.421e-120 350
LLPS-Sem-0902Selaginella moellendorffii76.061e-118 343
LLPS-Aon-0884Aotus nancymaae75.834e-113 329
LLPS-Pot-0850Populus trichocarpa75.477e-117 339
LLPS-Hov-0100Hordeum vulgare75.473e-117 340
LLPS-Php-0036Physcomitrella patens75.232e-118 343
LLPS-Orc-1874Oryctolagus cuniculus74.851e-88 265
LLPS-Chr-0021Chlamydomonas reinhardtii74.165e-113 329
LLPS-Chc-0490Chondrus crispus74.063e-111 325
LLPS-Mam-0488Macaca mulatta73.81e-120 349
LLPS-Maf-0453Macaca fascicularis73.81e-120 349
LLPS-Rhb-0198Rhinopithecus bieti73.367e-120 347
LLPS-Dio-0913Dipodomys ordii72.733e-72 224
LLPS-Vir-0811Vigna radiata72.453e-105 309
LLPS-Cas-3332Carlito syrichta70.947e-100 295
LLPS-Lep-1218Leersia perrieri70.816e-108 317
LLPS-Icp-1602Ictalurus punctatus70.181e-112 329
LLPS-Gog-0048Gorilla gorilla66.031e-94 282
LLPS-Mal-1042Mandrillus leucophaeus63.645e-79 241
LLPS-Dac-1610Daucus carota58.961e-82 250
LLPS-Cap-3073Cavia porcellus31.182e-26 106
LLPS-Myl-0690Myotis lucifugus31.182e-26 106