• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Paa-1461

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: GTP-binding nuclear protein Ran
Ensembl Gene: ENSPANG00000008799.2
Ensembl Protein: ENSPANP00000006461.1
Organism: Papio anubis
Taxa ID: 9555
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, P-body, OthersPredicted from orthologs(View)

▼ FUNCTION

GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAAQGEPQVQ  FKLVLVGDGG  TGKTTFVKRH  LTGEFEKKYV  ATLGVEVHPL  VFHTNRGPIK  60
61    FNVWDTAGQE  KFGGLRDGYY  IQAQCAIIMF  DVTSRVTYKN  VPNWHRDLVR  VCENIPIVLC  120
121   GNKVDIKDRK  VKAKSIVFHR  KKNLQYYDIS  AKSNYNFEKP  FLWLARKLIG  DPNLEFVAMP  180
181   ALAPPEVVMD  PALAAQYEHD  LEVAQTTALP  DEDDDL  216
Nucleotide CDS Sequence (FASTA)
1     ATGGCTGCGC  AGGGAGAGCC  CCAGGTCCAG  TTCAAACTTG  TATTGGTTGG  TGATGGTGGT  60
61    ACTGGAAAAA  CGACCTTCGT  GAAGCGTCAT  TTGACTGGTG  AATTTGAGAA  GAAGTATGTA  120
121   GCCACCTTGG  GTGTTGAGGT  TCATCCCCTA  GTGTTCCACA  CCAACAGAGG  ACCTATTAAA  180
181   TTCAATGTAT  GGGACACAGC  CGGCCAGGAG  AAATTCGGCG  GACTGAGAGA  TGGCTATTAT  240
241   ATCCAAGCCC  AGTGTGCCAT  CATCATGTTT  GATGTAACAT  CGAGAGTTAC  TTACAAGAAC  300
301   GTGCCTAACT  GGCACAGAGA  TCTGGTGCGA  GTGTGTGAAA  ACATCCCCAT  TGTGTTGTGT  360
361   GGTAACAAAG  TGGACATTAA  GGACAGGAAA  GTGAAGGCGA  AATCCATTGT  CTTCCACCGA  420
421   AAGAAGAATC  TTCAGTACTA  CGACATTTCT  GCCAAAAGTA  ACTACAACTT  TGAAAAGCCC  480
481   TTCCTCTGGC  TCGCTAGGAA  GCTCATTGGA  GACCCTAACT  TGGAATTTGT  TGCCATGCCT  540
541   GCTCTTGCCC  CACCGGAAGT  TGTCATGGAC  CCAGCTTTGG  CAGCGCAGTA  TGAGCACGAC  600
601   TTAGAGGTTG  CTCAGACAAC  TGCTCTCCCG  GATGAGGATG  ATGACCTGTG  A  651

▼ KEYWORD

ID
Family
Complete proteome
GTP-binding
Nucleotide-binding
Nucleus
Protein transport
Reference proteome
Transport

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Nucleus
Molecular Function
GTP binding
Molecular Function
GTPase activity
Biological Process
Nucleocytoplasmic transport
Biological Process
Protein transport

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Otg-1159Otolemur garnettii100.06e-161 451
LLPS-Loa-0259Loxodonta africana100.06e-161 451
LLPS-Urm-1096Ursus maritimus100.04e-90 268
LLPS-Nol-1720Nomascus leucogenys100.06e-161 451
LLPS-Ict-1214Ictidomys tridecemlineatus100.02e-151 426
LLPS-Eqc-0121Equus caballus100.03e-160 453
LLPS-Poa-0338Pongo abelii100.05e-161 452
LLPS-Caf-1791Canis familiaris100.05e-151 426
LLPS-Sus-3093Sus scrofa100.06e-161 451
LLPS-Mum-0705Mus musculus100.06e-161 451
LLPS-Ova-1077Ovis aries100.06e-161 451
LLPS-Ran-0351Rattus norvegicus100.06e-161 451
LLPS-Bot-3475Bos taurus100.06e-161 451
LLPS-Tut-0355Tursiops truncatus100.09e-161 451
LLPS-Fec-0798Felis catus99.516e-152 428
LLPS-Fud-0562Fukomys damarensis99.515e-151 425
LLPS-Fia-1549Ficedula albicollis98.612e-159 447
LLPS-Pes-1643Pelodiscus sinensis98.612e-159 447
LLPS-Anp-1731Anas platyrhynchos98.612e-159 447
LLPS-Mod-0590Monodelphis domestica98.612e-159 447
LLPS-Tag-1283Taeniopygia guttata98.612e-159 447
LLPS-Gaga-0464Gallus gallus98.612e-159 447
LLPS-Ora-0624Ornithorhynchus anatinus98.615e-160 449
LLPS-Dio-0913Dipodomys ordii98.524e-94 280
LLPS-Anc-0579Anolis carolinensis98.142e-157 442
LLPS-Mup-0142Mustela putorius furo98.097e-151 425
LLPS-Sah-0098Sarcophilus harrisii97.691e-157 442
LLPS-Xet-0648Xenopus tropicalis97.251e-155 437
LLPS-Mea-2578Mesocricetus auratus97.223e-157 441
LLPS-Pap-4706Pan paniscus96.772e-153 432
LLPS-Leo-0063Lepisosteus oculatus96.763e-156 439
LLPS-Scf-1096Scleropages formosus96.731e-154 435
LLPS-Chs-0659Chlorocebus sabaeus96.692e-104 305
LLPS-Meg-0288Meleagris gallopavo96.689e-152 427
LLPS-Lac-1951Latimeria chalumnae96.482e-97 287
LLPS-Man-1215Macaca nemestrina96.33e-152 429
LLPS-Hos-1106Homo sapiens96.33e-152 429
LLPS-Pat-2094Pan troglodytes96.33e-152 429
LLPS-Caj-0615Callithrix jacchus96.39e-152 429
LLPS-Cea-2779Cercocebus atys96.33e-152 429
LLPS-Aim-1266Ailuropoda melanoleuca96.282e-152 429
LLPS-Orc-1874Oryctolagus cuniculus95.763e-115 333
LLPS-Dar-1633Danio rerio94.865e-152 428
LLPS-Asm-0598Astyanax mexicanus94.391e-151 427
LLPS-Scm-0088Scophthalmus maximus93.691e-144 409
LLPS-Tar-0495Takifugu rubripes92.991e-146 414
LLPS-Mam-0488Macaca mulatta92.79e-157 441
LLPS-Maf-0453Macaca fascicularis92.79e-157 441
LLPS-Rhb-0198Rhinopithecus bieti92.274e-156 439
LLPS-Cii-0020Ciona intestinalis92.07e-99 291
LLPS-Cae-0207Caenorhabditis elegans91.756e-133 380
LLPS-Aon-0884Aotus nancymaae91.633e-143 406
LLPS-Orn-1179Oreochromis niloticus91.596e-146 413
LLPS-Pof-1043Poecilia formosa91.592e-146 414
LLPS-Ten-0261Tetraodon nigroviridis91.597e-145 410
LLPS-Orl-1353Oryzias latipes91.592e-146 414
LLPS-Gaa-1991Gasterosteus aculeatus91.599e-146 412
LLPS-Xim-2383Xiphophorus maculatus91.593e-146 414
LLPS-Cas-3332Carlito syrichta88.784e-128 366
LLPS-Drm-1290Drosophila melanogaster87.042e-139 396
LLPS-Icp-1602Ictalurus punctatus86.035e-141 401
LLPS-Gog-0048Gorilla gorilla85.641e-121 351
LLPS-Asg-0324Ashbya gossypii83.335e-127 365
LLPS-Gas-0209Galdieria sulphuraria83.011e-126 364
LLPS-Asni-0642Aspergillus niger82.847e-127 364
LLPS-Zyt-0072Zymoseptoria tritici82.842e-125 361
LLPS-Mal-1042Mandrillus leucophaeus82.541e-107 314
LLPS-Mua-0299Musa acuminata82.011e-111 327
LLPS-Scj-0424Schizosaccharomyces japonicus81.782e-126 363
LLPS-Sac-0082Saccharomyces cerevisiae81.693e-127 365
LLPS-Lem-0679Leptosphaeria maculans81.691e-125 362
LLPS-Scp-0426Schizosaccharomyces pombe81.69e-126 362
LLPS-Put-0150Puccinia triticina81.371e-117 341
LLPS-Tum-0025Tuber melanosporum81.377e-123 354
LLPS-Kop-1019Komagataella pastoris81.376e-122 352
LLPS-Scc-0453Schizosaccharomyces cryophilus81.314e-126 362
LLPS-Beb-0853Beauveria bassiana81.191e-120 348
LLPS-Pug-0651Puccinia graminis80.889e-117 338
LLPS-Aso-0315Aspergillus oryzae80.846e-126 362
LLPS-Asf-0348Aspergillus flavus80.776e-117 339
LLPS-Orp-0335Oryza punctata80.423e-109 320
LLPS-Ors-0144Oryza sativa80.421e-109 321
LLPS-Org-0569Oryza glaberrima80.421e-109 321
LLPS-Orb-0368Oryza barthii80.421e-109 321
LLPS-Orgl-0598Oryza glumaepatula80.421e-109 321
LLPS-Miv-1044Microbotryum violaceum80.399e-121 348
LLPS-Asfu-0631Aspergillus fumigatus80.372e-127 365
LLPS-Orbr-0020Oryza brachyantha80.213e-108 317
LLPS-Ori-0631Oryza indica80.213e-108 317
LLPS-Sei-2266Setaria italica80.213e-109 320
LLPS-Map-0086Magnaporthe poae80.096e-116 337
LLPS-Orr-1637Oryza rufipogon80.09e-109 322
LLPS-Orm-1802Oryza meridionalis80.02e-109 322
LLPS-Nec-0290Neurospora crassa80.02e-114 333
LLPS-Spr-0530Sporisorium reilianum79.914e-120 347
LLPS-Usm-0386Ustilago maydis79.918e-116 336
LLPS-Asn-0461Aspergillus nidulans79.912e-125 361
LLPS-Abg-0716Absidia glauca79.913e-121 350
LLPS-Pyt-1144Pyrenophora teres79.914e-125 360
LLPS-Mel-0718Melampsora laricipopulina79.98e-120 347
LLPS-Crn-1068Cryptococcus neoformans79.95e-125 360
LLPS-Orni-1566Oryza nivara79.791e-102 320
LLPS-Blg-0743Blumeria graminis79.721e-116 338
LLPS-Sob-2059Sorghum bicolor79.685e-108 317
LLPS-Zem-0744Zea mays79.685e-108 317
LLPS-Tra-0810Triticum aestivum79.682e-108 318
LLPS-Yal-0211Yarrowia lipolytica79.411e-118 343
LLPS-Phn-0266Phaeosphaeria nodorum79.372e-69 215
LLPS-Trv-0082Trichoderma virens79.367e-117 339
LLPS-Tru-1110Triticum urartu79.276e-111 323
LLPS-Dos-0253Dothistroma septosporum79.256e-124 357
LLPS-Trr-0331Trichoderma reesei79.172e-116 338
LLPS-Brd-0086Brachypodium distachyon79.143e-108 317
LLPS-Cogr-1051Colletotrichum graminicola78.92e-115 335
LLPS-Mao-0368Magnaporthe oryzae78.871e-115 336
LLPS-Cog-0062Colletotrichum gloeosporioides78.84e-115 335
LLPS-Mae-0647Manihot esculenta78.542e-118 343
LLPS-Scs-0133Sclerotinia sclerotiorum78.56e-116 337
LLPS-Asc-0985Aspergillus clavatus78.52e-120 347
LLPS-Fus-0442Fusarium solani78.441e-115 335
LLPS-Fuo-0579Fusarium oxysporum78.441e-115 335
LLPS-Fuv-0320Fusarium verticillioides78.441e-115 335
LLPS-Phv-0377Phaseolus vulgaris78.054e-117 340
LLPS-Gor-0787Gossypium raimondii78.058e-117 340
LLPS-Art-1567Arabidopsis thaliana78.051e-109 321
LLPS-Viv-1397Vitis vinifera78.056e-117 339
LLPS-Prp-0588Prunus persica78.056e-117 339
LLPS-Coc-0074Corchorus capsularis78.052e-117 340
LLPS-Php-0036Physcomitrella patens78.059e-116 337
LLPS-Hea-0801Helianthus annuus78.053e-117 340
LLPS-Arl-2721Arabidopsis lyrata78.051e-109 321
LLPS-Via-0822Vigna angularis78.054e-117 340
LLPS-Cym-0368Cyanidioschyzon merolae78.046e-121 350
LLPS-Ved-0381Verticillium dahliae77.982e-116 338
LLPS-Brr-1559Brassica rapa77.566e-117 339
LLPS-Bro-1701Brassica oleracea77.566e-117 339
LLPS-Thc-0090Theobroma cacao77.567e-116 337
LLPS-Brn-1596Brassica napus77.562e-117 342
LLPS-Glm-0094Glycine max77.562e-115 338
LLPS-Met-0210Medicago truncatula77.562e-116 338
LLPS-Cus-0588Cucumis sativus77.565e-116 337
LLPS-Pot-0850Populus trichocarpa77.184e-116 337
LLPS-Nef-0924Neosartorya fischeri77.12e-118 343
LLPS-Sol-1594Solanum lycopersicum77.072e-114 333
LLPS-Sot-1646Solanum tuberosum77.072e-114 333
LLPS-Pytr-0928Pyrenophora triticirepentis76.644e-117 340
LLPS-Chc-0490Chondrus crispus75.71e-110 323
LLPS-Dac-1610Daucus carota75.682e-79 242
LLPS-Chr-0021Chlamydomonas reinhardtii75.616e-111 324
LLPS-Gag-0249Gaeumannomyces graminis75.342e-110 323
LLPS-Hov-0100Hordeum vulgare75.02e-111 325
LLPS-Nia-0306Nicotiana attenuata74.777e-117 340
LLPS-Amt-1779Amborella trichopoda74.311e-112 328
LLPS-Coo-0003Colletotrichum orbiculare74.032e-111 326
LLPS-Ast-0600Aspergillus terreus73.827e-121 350
LLPS-Osl-0319Ostreococcus lucimarinus73.733e-116 337
LLPS-Sem-0902Selaginella moellendorffii73.614e-114 332
LLPS-Vir-0811Vigna radiata73.69e-106 310
LLPS-Lep-1218Leersia perrieri70.564e-107 315
LLPS-Cap-3073Cavia porcellus32.541e-27 110
LLPS-Myl-0690Myotis lucifugus32.541e-27 110