• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Dio-0913
Ran

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: GTP-binding nuclear protein Ran
Gene Name: Ran
Ensembl Gene: ENSDORG00000028664.1
Ensembl Protein: ENSDORP00000025311.1
Organism: Dipodomys ordii
Taxa ID: 10020
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Centrosome/Spindle pole body, P-body, Stress granule, OthersPredicted from orthologs(View)

▼ FUNCTION

GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MWCLGIECRA  SCMQGKHSTT  FPGLVQAFIQ  SAFESVYCVN  RTQCAIIMFD  VTSRVTYKNV  60
61    PNWHRDLVRV  CENIPIVLCG  NKVDIKDRKV  KAKSIVFHRK  KNLQYYDISA  KSNYNFEKPF  120
121   LWLARKLIGD  PNLEFVAMPA  LAPPEVVMDP  ALAAQYEHDL  EVAQTTALPD  EDDDL  175
Nucleotide CDS Sequence (FASTA)
1     ATGTGGTGCT  TAGGAATTGA  ATGCAGGGCT  TCATGCATGC  AAGGCAAGCA  CTCTACCACC  60
61    TTCCCAGGCC  TTGTTCAAGC  TTTTATACAA  AGTGCATTCG  AATCCGTATA  TTGTGTTAAC  120
121   AGAACCCAAT  GCGCCATCAT  AATGTTTGAT  GTAACATCAA  GAGTTACTTA  CAAGAACGTG  180
181   CCTAACTGGC  ATAGAGATCT  GGTGCGAGTG  TGTGAGAACA  TCCCCATTGT  GTTGTGTGGC  240
241   AACAAAGTGG  ACATCAAGGA  CAGGAAAGTG  AAGGCAAAGT  CTATTGTCTT  CCACCGGAAG  300
301   AAGAACCTCC  AGTACTACGA  CATTTCTGCC  AAAAGTAACT  ACAACTTTGA  GAAGCCCTTC  360
361   CTCTGGCTCG  CTAGAAAGCT  CATTGGAGAC  CCTAACTTGG  AGTTTGTCGC  CATGCCTGCT  420
421   CTTGCCCCAC  CGGAGGTGGT  CATGGATCCA  GCCTTGGCCG  CGCAGTACGA  GCATGACCTG  480
481   GAGGTTGCTC  AGACCACCGC  TCTCCCGGAT  GAGGATGACG  ACCTGTGA  528

▼ KEYWORD

ID
Family
Complete proteome
GTP-binding
Nucleotide-binding
Nucleus
Protein transport
Reference proteome
Transport

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Nucleus
Molecular Function
GTP binding
Molecular Function
GTPase activity
Biological Process
Nucleocytoplasmic transport
Biological Process
Protein transport

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Urm-1096Ursus maritimus100.02e-90 266
LLPS-Eqc-0121Equus caballus99.255e-93 280
LLPS-Man-1215Macaca nemestrina98.521e-93 279
LLPS-Loa-0259Loxodonta africana98.523e-94 280
LLPS-Hos-1106Homo sapiens98.521e-93 279
LLPS-Pat-2094Pan troglodytes98.521e-93 279
LLPS-Fec-0798Felis catus98.521e-93 279
LLPS-Orc-1874Oryctolagus cuniculus98.524e-94 278
LLPS-Otg-1159Otolemur garnettii98.523e-94 280
LLPS-Poa-0338Pongo abelii98.524e-94 280
LLPS-Caf-1791Canis familiaris98.529e-94 278
LLPS-Nol-1720Nomascus leucogenys98.523e-94 280
LLPS-Ict-1214Ictidomys tridecemlineatus98.523e-94 280
LLPS-Sus-3093Sus scrofa98.523e-94 280
LLPS-Cea-2779Cercocebus atys98.521e-93 279
LLPS-Mum-0705Mus musculus98.523e-94 280
LLPS-Fud-0562Fukomys damarensis98.526e-94 278
LLPS-Caj-0615Callithrix jacchus98.527e-93 278
LLPS-Bot-3475Bos taurus98.523e-94 280
LLPS-Tut-0355Tursiops truncatus98.526e-94 280
LLPS-Paa-1461Papio anubis98.523e-94 280
LLPS-Aim-1266Ailuropoda melanoleuca98.521e-93 278
LLPS-Ova-1077Ovis aries98.523e-94 280
LLPS-Ran-0351Rattus norvegicus98.523e-94 280
LLPS-Mup-0142Mustela putorius furo97.792e-92 275
LLPS-Chs-0659Chlorocebus sabaeus96.882e-37 132
LLPS-Anp-1731Anas platyrhynchos96.32e-92 275
LLPS-Meg-0288Meleagris gallopavo96.33e-92 275
LLPS-Mod-0590Monodelphis domestica96.32e-92 275
LLPS-Fia-1549Ficedula albicollis96.32e-92 275
LLPS-Pes-1643Pelodiscus sinensis96.32e-92 275
LLPS-Anc-0579Anolis carolinensis96.32e-92 275
LLPS-Tag-1283Taeniopygia guttata96.31e-92 276
LLPS-Gaga-0464Gallus gallus96.32e-92 275
LLPS-Sah-0098Sarcophilus harrisii96.32e-92 275
LLPS-Ora-0624Ornithorhynchus anatinus96.39e-93 276
LLPS-Xet-0648Xenopus tropicalis95.566e-91 271
LLPS-Mea-2578Mesocricetus auratus95.561e-91 273
LLPS-Leo-0063Lepisosteus oculatus94.813e-91 272
LLPS-Scf-1096Scleropages formosus94.816e-91 271
LLPS-Lac-1951Latimeria chalumnae94.032e-37 132
LLPS-Cas-3332Carlito syrichta93.751e-93 277
LLPS-Pap-4706Pan paniscus93.389e-87 261
LLPS-Dar-1633Danio rerio93.339e-90 268
LLPS-Asm-0598Astyanax mexicanus93.336e-90 269
LLPS-Tar-0495Takifugu rubripes93.331e-88 266
LLPS-Mam-0488Macaca mulatta93.068e-95 282
LLPS-Maf-0453Macaca fascicularis93.068e-95 282
LLPS-Aon-0884Aotus nancymaae92.597e-88 263
LLPS-Rhb-0198Rhinopithecus bieti92.364e-94 280
LLPS-Pof-1043Poecilia formosa91.851e-87 263
LLPS-Orn-1179Oreochromis niloticus91.851e-87 263
LLPS-Orl-1353Oryzias latipes91.859e-88 263
LLPS-Gaa-1991Gasterosteus aculeatus91.851e-87 263
LLPS-Xim-2383Xiphophorus maculatus91.852e-87 263
LLPS-Cii-0020Ciona intestinalis91.258e-47 157
LLPS-Scm-0088Scophthalmus maximus91.119e-87 261
LLPS-Ten-0261Tetraodon nigroviridis91.118e-87 261
LLPS-Cae-0207Caenorhabditis elegans87.81e-76 235
LLPS-Drm-1290Drosophila melanogaster87.414e-82 249
LLPS-Mua-0299Musa acuminata81.036e-63 201
LLPS-Abg-0716Absidia glauca80.741e-75 232
LLPS-Icp-1602Ictalurus punctatus80.673e-79 242
LLPS-Asc-0985Aspergillus clavatus80.291e-77 237
LLPS-Gog-0048Gorilla gorilla80.01e-69 216
LLPS-Phn-0266Phaeosphaeria nodorum79.373e-70 215
LLPS-Orp-0335Oryza punctata79.311e-61 196
LLPS-Ors-0144Oryza sativa79.316e-62 197
LLPS-Orr-1637Oryza rufipogon79.316e-61 197
LLPS-Orm-1802Oryza meridionalis79.311e-61 197
LLPS-Org-0569Oryza glaberrima79.316e-62 197
LLPS-Orb-0368Oryza barthii79.316e-62 197
LLPS-Orgl-0598Oryza glumaepatula79.316e-62 197
LLPS-Gas-0209Galdieria sulphuraria79.262e-73 227
LLPS-Orbr-0020Oryza brachyantha78.951e-60 194
LLPS-Zem-1274Zea mays78.955e-60 192
LLPS-Ori-0631Oryza indica78.951e-60 194
LLPS-Scc-0453Schizosaccharomyces cryophilus78.952e-73 226
LLPS-Orni-1566Oryza nivara78.951e-56 195
LLPS-Scp-0426Schizosaccharomyces pombe78.953e-73 226
LLPS-Scj-0424Schizosaccharomyces japonicus78.953e-73 226
LLPS-Sei-2266Setaria italica78.953e-61 196
LLPS-Sac-0082Saccharomyces cerevisiae78.831e-74 230
LLPS-Nef-0924Neosartorya fischeri78.12e-75 231
LLPS-Asfu-0631Aspergillus fumigatus78.12e-75 232
LLPS-Asg-0324Ashbya gossypii78.12e-74 229
LLPS-Aso-0315Aspergillus oryzae78.11e-74 229
LLPS-Sob-2059Sorghum bicolor78.071e-59 192
LLPS-Tra-0810Triticum aestivum78.071e-60 194
LLPS-Gag-0249Gaeumannomyces graminis77.447e-65 205
LLPS-Ast-0600Aspergillus terreus77.371e-73 228
LLPS-Pytr-0928Pyrenophora triticirepentis77.371e-72 224
LLPS-Asn-0461Aspergillus nidulans77.377e-74 228
LLPS-Pyt-1144Pyrenophora teres77.371e-72 224
LLPS-Zyt-0072Zymoseptoria tritici77.372e-73 227
LLPS-Brd-0086Brachypodium distachyon77.193e-60 193
LLPS-Mal-1042Mandrillus leucophaeus77.042e-65 204
LLPS-Mae-0647Manihot esculenta76.521e-69 217
LLPS-Php-0036Physcomitrella patens76.525e-68 213
LLPS-Spr-0530Sporisorium reilianum75.943e-65 206
LLPS-Crn-1068Cryptococcus neoformans75.948e-72 223
LLPS-Tum-0025Tuber melanosporum75.912e-72 224
LLPS-Viv-1397Vitis vinifera75.761e-68 214
LLPS-Gor-0787Gossypium raimondii75.762e-68 214
LLPS-Art-1567Arabidopsis thaliana75.761e-61 197
LLPS-Phv-0377Phaseolus vulgaris75.769e-69 215
LLPS-Prp-0588Prunus persica75.761e-68 214
LLPS-Coc-0074Corchorus capsularis75.765e-69 216
LLPS-Hea-0801Helianthus annuus75.768e-69 215
LLPS-Via-0822Vigna angularis75.761e-68 215
LLPS-Arl-2721Arabidopsis lyrata75.761e-61 197
LLPS-Pot-0850Populus trichocarpa75.577e-68 213
LLPS-Beb-0853Beauveria bassiana75.512e-69 216
LLPS-Tru-1110Triticum urartu75.361e-69 216
LLPS-Miv-1044Microbotryum violaceum75.198e-72 222
LLPS-Usm-0386Ustilago maydis75.196e-60 192
LLPS-Chc-0490Chondrus crispus75.192e-68 214
LLPS-Brr-1559Brassica rapa75.01e-68 214
LLPS-Amt-1779Amborella trichopoda75.01e-64 204
LLPS-Nia-0306Nicotiana attenuata75.03e-68 214
LLPS-Bro-1701Brassica oleracea75.01e-68 214
LLPS-Brn-1596Brassica napus75.09e-69 216
LLPS-Glm-1374Glycine max75.03e-68 214
LLPS-Thc-0090Theobroma cacao75.02e-67 212
LLPS-Met-0210Medicago truncatula75.03e-68 214
LLPS-Cus-0588Cucumis sativus75.09e-68 212
LLPS-Asni-0642Aspergillus niger74.832e-75 232
LLPS-Lem-0679Leptosphaeria maculans74.832e-73 227
LLPS-Coo-0003Colletotrichum orbiculare74.473e-64 204
LLPS-Put-0150Puccinia triticina74.441e-63 202
LLPS-Sol-1594Solanum lycopersicum74.242e-66 209
LLPS-Dac-1610Daucus carota74.241e-67 210
LLPS-Sot-1646Solanum tuberosum74.242e-66 209
LLPS-Blg-0743Blumeria graminis74.133e-66 208
LLPS-Cym-0368Cyanidioschyzon merolae73.888e-66 207
LLPS-Pug-0651Puccinia graminis73.685e-63 200
LLPS-Trr-0331Trichoderma reesei73.473e-66 208
LLPS-Yal-0211Yarrowia lipolytica73.433e-72 223
LLPS-Asf-0348Aspergillus flavus73.435e-66 207
LLPS-Mel-0718Melampsora laricipopulina72.933e-67 211
LLPS-Map-0086Magnaporthe poae72.921e-65 207
LLPS-Mao-0368Magnaporthe oryzae72.922e-65 206
LLPS-Trv-0082Trichoderma virens72.799e-66 207
LLPS-Dos-0253Dothistroma septosporum72.733e-72 224
LLPS-Sem-0902Selaginella moellendorffii72.731e-64 204
LLPS-Scs-0133Sclerotinia sclerotiorum72.221e-64 204
LLPS-Cogr-1051Colletotrichum graminicola72.111e-64 204
LLPS-Vir-0811Vigna radiata71.971e-64 204
LLPS-Chr-0021Chlamydomonas reinhardtii71.979e-63 199
LLPS-Fus-0442Fusarium solani71.431e-64 204
LLPS-Cog-0062Colletotrichum gloeosporioides71.433e-64 203
LLPS-Fuo-0579Fusarium oxysporum71.431e-64 204
LLPS-Ved-0381Verticillium dahliae71.431e-64 204
LLPS-Osl-0319Ostreococcus lucimarinus71.432e-64 204
LLPS-Fuv-0320Fusarium verticillioides71.431e-64 204
LLPS-Kop-1019Komagataella pastoris71.333e-68 213
LLPS-Hov-0100Hordeum vulgare70.996e-63 200
LLPS-Nec-0290Neurospora crassa70.837e-64 202
LLPS-Lep-1218Leersia perrieri68.182e-59 191
LLPS-Cis-0264Ciona savignyi36.562e-1060.8
LLPS-Cap-3073Cavia porcellus33.78e-1058.9
LLPS-Myl-0690Myotis lucifugus33.78e-1058.9