• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Paa-1177

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: GTP-binding nuclear protein Ran
Ensembl Gene: ENSPANG00000017209.2
Ensembl Protein: ENSPANP00000047615.1
Organism: Papio anubis
Taxa ID: 9555
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Centrosome/Spindle pole body, Stress granulePredicted from orthologs(View)

▼ FUNCTION

GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     RRRRLRLRRL  NCASAIFPAS  VGRARRRFWK  LVLVGDGGTG  KTTFVKRHLT  GEFEKKYVAT  60
61    LGVEVHPLVF  HTNRGPIKFN  VWDTAGQEKF  GGLRDGYYIQ  AQCAIIMFDV  TSRVTYKNVP  120
121   NWHRDLVRVC  ENIPIVLCGN  KVDIKDRKVK  AKSIVFHRKK  NLQYYDISAK  SNYNFEKPFL  180
181   WLARKLIGDP  NLEFVAMPAL  APPEVVMDPA  LAAQYEHDLE  VAQTTALPDE  DDDL  234
Nucleotide CDS Sequence (FASTA)
1     ATGGCTGCGC  AGGGAGAGCC  CCAGGTCCAG  TTCAAACTTG  TATTGGTTGG  TGATGGTGGT  60
61    ACTGGAAAAA  CGACCTTCGT  GAAGCGTCAT  TTGACTGGTG  AATTTGAGAA  GAAGTATGTA  120
121   GCCACCTTGG  GTGTTGAGGT  TCATCCCCTA  GTGTTCCACA  CCAACAGAGG  ACCTATTAAA  180
181   TTCAATGTAT  GGGACACAGC  CGGCCAGGAG  AAATTCGGCG  GACTGAGAGA  TGGCTATTAT  240
241   ATCCAAGGGA  TGGGGATTCA  CCATGTTGCC  CATGCTGGTC  TGGAACTCAT  GAGCTCAGCC  300
301   CAGTGTGCCA  TCATCATGTT  TGATGTAACA  TCGAGAGTTA  CTTACAAGAA  CGTGCCTAAC  360
361   TGGCATAGAG  ATCTGGTGCG  AGTGTGTGAA  AACATCCCCA  TTGTGTTGTG  TGGTAACAAA  420
421   GTGGACATTA  AGGACAGGAA  AGTGAAGGCG  AAATCCATTG  TCTTCCACCG  AAAGAAGAAT  480
481   CTTCAGTACT  ACGACATTTC  TGCCAAAAGT  AACTACAACT  TTGAAAAGCC  CTTCCTCTGG  540
541   CTCGCTAGGA  AGCTCATTGG  AGACCCTAAC  TTGGAATTTG  TTGCCATGCC  TGCTCTTGCC  600
601   CCACCGGAAG  TTGTCATGGA  CCCAGCTTTG  GCAGCGCAGT  ATGAGCACGA  CTTAGAGGTT  660
661   GCTCAGACAA  CTGCTCTCCC  GGATGAGGAT  GATGACCTGT  GA  702

▼ KEYWORD

ID
Family
Complete proteome
GTP-binding
Nucleotide-binding
Nucleus
Protein transport
Reference proteome
Transport

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Nucleus
Molecular Function
GTP binding
Molecular Function
GTPase activity
Biological Process
Nucleocytoplasmic transport
Biological Process
Protein transport

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Ict-1214Ictidomys tridecemlineatus100.07e-151 426
LLPS-Man-1215Macaca nemestrina100.04e-167 468
LLPS-Pat-2094Pan troglodytes100.04e-167 468
LLPS-Urm-1096Ursus maritimus100.02e-89 266
LLPS-Hos-1106Homo sapiens100.04e-167 468
LLPS-Aim-1266Ailuropoda melanoleuca100.03e-150 424
LLPS-Cea-2779Cercocebus atys100.04e-167 468
LLPS-Caj-0615Callithrix jacchus100.02e-166 468
LLPS-Eqc-0121Equus caballus99.517e-151 430
LLPS-Fud-0562Fukomys damarensis99.511e-150 425
LLPS-Mup-0142Mustela putorius furo98.554e-149 421
LLPS-Meg-0288Meleagris gallopavo98.541e-149 423
LLPS-Dio-0913Dipodomys ordii98.522e-93 278
LLPS-Anc-0579Anolis carolinensis98.065e-150 424
LLPS-Fec-0798Felis catus97.778e-163 457
LLPS-Scf-1096Scleropages formosus96.63e-147 417
LLPS-Lac-1951Latimeria chalumnae96.382e-93 278
LLPS-Poa-0338Pongo abelii96.36e-152 429
LLPS-Nol-1720Nomascus leucogenys96.35e-152 429
LLPS-Loa-0259Loxodonta africana96.35e-152 429
LLPS-Otg-1159Otolemur garnettii96.35e-152 429
LLPS-Bot-3475Bos taurus96.35e-152 429
LLPS-Ova-1077Ovis aries96.35e-152 429
LLPS-Ran-0351Rattus norvegicus96.35e-152 429
LLPS-Sus-3093Sus scrofa96.35e-152 429
LLPS-Mum-0705Mus musculus96.35e-152 429
LLPS-Caf-1791Canis familiaris95.857e-151 426
LLPS-Orc-1874Oryctolagus cuniculus95.762e-114 332
LLPS-Chs-0659Chlorocebus sabaeus95.748e-95 281
LLPS-Dar-1633Danio rerio95.151e-145 413
LLPS-Asm-0598Astyanax mexicanus95.159e-146 413
LLPS-Tag-1283Taeniopygia guttata94.911e-150 425
LLPS-Gaga-0464Gallus gallus94.912e-150 425
LLPS-Anp-1731Anas platyrhynchos94.912e-150 425
LLPS-Mod-0590Monodelphis domestica94.912e-150 425
LLPS-Fia-1549Ficedula albicollis94.912e-150 425
LLPS-Pes-1643Pelodiscus sinensis94.912e-150 425
LLPS-Ora-0624Ornithorhynchus anatinus94.917e-151 426
LLPS-Mea-0323Mesocricetus auratus94.663e-145 412
LLPS-Tut-0355Tursiops truncatus94.629e-154 434
LLPS-Sah-0098Sarcophilus harrisii93.981e-148 421
LLPS-Tar-0495Takifugu rubripes93.727e-143 405
LLPS-Pof-1043Poecilia formosa93.692e-144 410
LLPS-Xim-2383Xiphophorus maculatus93.695e-144 409
LLPS-Orl-1353Oryzias latipes93.692e-144 410
LLPS-Aon-0884Aotus nancymaae93.693e-140 399
LLPS-Xet-0648Xenopus tropicalis93.589e-147 416
LLPS-Leo-0063Lepisosteus oculatus93.524e-148 419
LLPS-Scm-0088Scophthalmus maximus93.22e-143 407
LLPS-Orn-1179Oreochromis niloticus93.23e-143 407
LLPS-Gaa-1991Gasterosteus aculeatus93.26e-143 406
LLPS-Pap-4706Pan paniscus93.093e-144 409
LLPS-Ten-0261Tetraodon nigroviridis92.275e-141 401
LLPS-Cii-0020Ciona intestinalis92.02e-98 291
LLPS-Cae-0207Caenorhabditis elegans91.241e-131 377
LLPS-Drm-1290Drosophila melanogaster89.324e-136 389
LLPS-Mam-0488Macaca mulatta89.277e-148 419
LLPS-Maf-0453Macaca fascicularis89.277e-148 419
LLPS-Rhb-0198Rhinopithecus bieti88.843e-147 417
LLPS-Cas-3332Carlito syrichta88.781e-127 366
LLPS-Icp-1602Ictalurus punctatus86.434e-135 387
LLPS-Gog-0048Gorilla gorilla85.643e-121 350
LLPS-Scp-0426Schizosaccharomyces pombe83.332e-124 359
LLPS-Scj-0424Schizosaccharomyces japonicus83.332e-124 358
LLPS-Sac-0082Saccharomyces cerevisiae83.334e-126 363
LLPS-Asc-0985Aspergillus clavatus83.251e-118 344
LLPS-Lem-0679Leptosphaeria maculans82.844e-124 358
LLPS-Scc-0453Schizosaccharomyces cryophilus82.843e-124 358
LLPS-Asg-0324Ashbya gossypii82.841e-125 362
LLPS-Beb-0853Beauveria bassiana82.691e-118 344
LLPS-Mal-1042Mandrillus leucophaeus82.545e-107 313
LLPS-Gas-0209Galdieria sulphuraria82.522e-125 362
LLPS-Asfu-0631Aspergillus fumigatus82.359e-126 362
LLPS-Aso-0315Aspergillus oryzae82.353e-124 358
LLPS-Pyt-1144Pyrenophora teres82.356e-124 358
LLPS-Zyt-0072Zymoseptoria tritici82.352e-124 359
LLPS-Asni-0642Aspergillus niger82.351e-125 362
LLPS-Spr-0530Sporisorium reilianum81.863e-117 340
LLPS-Usm-0386Ustilago maydis81.863e-113 330
LLPS-Nef-0924Neosartorya fischeri81.682e-116 338
LLPS-Mua-0299Musa acuminata81.483e-110 324
LLPS-Blg-0743Blumeria graminis81.376e-115 335
LLPS-Asf-0348Aspergillus flavus81.372e-115 336
LLPS-Asn-0461Aspergillus nidulans81.372e-123 357
LLPS-Trr-0331Trichoderma reesei81.252e-115 336
LLPS-Abg-0716Absidia glauca81.079e-120 347
LLPS-Mao-0368Magnaporthe oryzae80.982e-114 333
LLPS-Map-0086Magnaporthe poae80.981e-114 334
LLPS-Put-0150Puccinia triticina80.884e-116 338
LLPS-Dos-0253Dothistroma septosporum80.889e-122 352
LLPS-Kop-1019Komagataella pastoris80.882e-120 348
LLPS-Tum-0025Tuber melanosporum80.881e-121 352
LLPS-Crn-1068Cryptococcus neoformans80.882e-123 356
LLPS-Trv-0082Trichoderma virens80.777e-115 335
LLPS-Scs-0133Sclerotinia sclerotiorum80.497e-114 332
LLPS-Pug-0651Puccinia graminis80.393e-115 336
LLPS-Cogr-1051Colletotrichum graminicola80.292e-113 331
LLPS-Miv-1044Microbotryum violaceum79.92e-119 346
LLPS-Orr-1637Oryza rufipogon79.892e-107 319
LLPS-Orm-1802Oryza meridionalis79.893e-108 319
LLPS-Org-0569Oryza glaberrima79.892e-108 318
LLPS-Orp-0335Oryza punctata79.895e-108 317
LLPS-Ors-0144Oryza sativa79.892e-108 318
LLPS-Orgl-0598Oryza glumaepatula79.892e-108 318
LLPS-Orb-0368Oryza barthii79.892e-108 318
LLPS-Fuo-0579Fusarium oxysporum79.811e-113 331
LLPS-Ved-0381Verticillium dahliae79.811e-113 332
LLPS-Fus-0442Fusarium solani79.811e-113 331
LLPS-Cog-0062Colletotrichum gloeosporioides79.813e-113 330
LLPS-Fuv-0320Fusarium verticillioides79.811e-113 331
LLPS-Zem-1274Zea mays79.686e-107 315
LLPS-Orbr-0020Oryza brachyantha79.683e-107 315
LLPS-Sei-2266Setaria italica79.686e-108 317
LLPS-Ori-0631Oryza indica79.683e-107 315
LLPS-Orni-1566Oryza nivara79.683e-101 317
LLPS-Nec-0290Neurospora crassa79.513e-113 330
LLPS-Mel-0718Melampsora laricipopulina79.413e-118 343
LLPS-Phn-0266Phaeosphaeria nodorum79.374e-69 215
LLPS-Tru-1110Triticum urartu79.272e-110 323
LLPS-Sob-2059Sorghum bicolor79.147e-107 315
LLPS-Tra-0810Triticum aestivum79.143e-107 315
LLPS-Pytr-0928Pyrenophora triticirepentis78.925e-116 337
LLPS-Yal-0211Yarrowia lipolytica78.924e-117 340
LLPS-Brd-0086Brachypodium distachyon78.618e-107 314
LLPS-Mae-0647Manihot esculenta78.053e-117 341
LLPS-Chc-0490Chondrus crispus77.67e-109 319
LLPS-Prp-0588Prunus persica77.561e-115 337
LLPS-Coc-0074Corchorus capsularis77.563e-116 338
LLPS-Viv-1397Vitis vinifera77.569e-116 337
LLPS-Gor-0787Gossypium raimondii77.562e-115 337
LLPS-Art-1567Arabidopsis thaliana77.562e-108 319
LLPS-Phv-0377Phaseolus vulgaris77.566e-116 338
LLPS-Via-0822Vigna angularis77.566e-116 338
LLPS-Arl-2721Arabidopsis lyrata77.562e-108 319
LLPS-Hea-0801Helianthus annuus77.565e-116 338
LLPS-Php-0036Physcomitrella patens77.561e-114 334
LLPS-Bro-1701Brassica oleracea77.079e-116 337
LLPS-Pot-0850Populus trichocarpa77.077e-115 335
LLPS-Brr-1559Brassica rapa77.079e-116 337
LLPS-Nia-0306Nicotiana attenuata77.073e-115 337
LLPS-Cus-0588Cucumis sativus77.078e-115 335
LLPS-Met-0210Medicago truncatula77.072e-115 336
LLPS-Brn-1596Brassica napus77.072e-116 340
LLPS-Glm-0094Glycine max77.075e-114 335
LLPS-Thc-0090Theobroma cacao77.071e-114 334
LLPS-Amt-1779Amborella trichopoda76.595e-111 325
LLPS-Sot-1646Solanum tuberosum76.592e-113 331
LLPS-Sol-1594Solanum lycopersicum76.592e-113 331
LLPS-Dac-1610Daucus carota75.684e-79 242
LLPS-Gag-0249Gaeumannomyces graminis75.584e-109 321
LLPS-Osl-0319Ostreococcus lucimarinus75.243e-114 333
LLPS-Chr-0021Chlamydomonas reinhardtii75.129e-110 322
LLPS-Sem-0902Selaginella moellendorffii75.123e-111 326
LLPS-Ast-0600Aspergillus terreus74.892e-119 347
LLPS-Cym-0368Cyanidioschyzon merolae74.894e-119 346
LLPS-Coo-0003Colletotrichum orbiculare74.772e-109 321
LLPS-Hov-0100Hordeum vulgare74.513e-110 323
LLPS-Vir-0811Vigna radiata73.63e-105 310
LLPS-Lep-1218Leersia perrieri69.446e-106 312
LLPS-Cap-3073Cavia porcellus31.763e-27 109
LLPS-Myl-0690Myotis lucifugus31.763e-27 109