• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Orp-1774

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: DNA repair protein RAD51 homolog
Ensembl Gene: OPUNC11G16450
Ensembl Protein: OPUNC11G16450.1
Organism: Oryza punctata
Taxa ID: 4537
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
DNA damage foci, OthersPredicted from orthologs(View)

▼ FUNCTION

Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Unwinds duplex DNA. Component of the meiotic recombination pathway. Seems to play a role in mediating chromosome homology search, chromosome pairing and synapsis at early stages and probably chromosome crossing-over at later stages in meiosis. Probably is involved in the repair of meiotic double strand breaks (DBSs) and in homologous recombination.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblOPUNC11G16450.1OPUNC11G16450.1
UniProtA0A0E0MH83, A0A0E0MH83_ORYPU

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSTSAAAAAA  EQQQEEGEHG  PFPIEQLQAS  GIAALDVKKL  KDSGLYTVES  VAYTPRKDLL  60
61    QIKGITSKLV  PLGFTSASQL  HAQRLEIIQV  TTGSRELDKI  LDGGIETGSI  TEIYGEFRSG  120
121   KTQLCHTLCV  TCQLPLDQGG  GEGKALYIDA  EGTFRPQRLL  QIADRFGLNG  ADVLENVAYA  180
181   RAYNTDHQSR  LLLEAASMMI  ETRFALMIVD  SATALYRTDF  SGRGELSARQ  MHMAKFLRSL  240
241   QKLADEFGVA  VVITNQVVAQ  VDGSAMFAGP  QIKPIGGNIM  AHASTTRLAL  RKGRGEERIC  300
301   KVISSPCLAE  AEARFQIASE  GVADVKD  327
Nucleotide CDS Sequence (FASTA)
1     ATGTCGACGT  CGGCGGCGGC  GGCGGCGGCG  GAGCAGCAGC  AGGAGGAGGG  GGAGCACGGG  60
61    CCGTTCCCCA  TCGAGCAGCT  GCAGGCATCT  GGAATTGCTG  CTCTGGATGT  GAAAAAGCTC  120
121   AAGGATTCTG  GTCTGTACAC  AGTGGAGTCT  GTGGCCTATA  CTCCAAGGAA  AGACCTTTTG  180
181   CAAATCAAAG  GAATTACATC  GAAGCTAGTC  CCATTGGGAT  TTACAAGTGC  GAGCCAACTT  240
241   CATGCACAAA  GGCTGGAGAT  TATTCAAGTG  ACAACTGGCT  CTAGAGAGCT  TGATAAGATT  300
301   TTGGATGGGG  GGATAGAAAC  TGGCTCTATC  ACAGAGATTT  ATGGTGAATT  CCGATCAGGC  360
361   AAGACTCAGC  TGTGCCACAC  GCTGTGTGTC  ACATGTCAGC  TTCCACTGGA  CCAAGGTGGT  420
421   GGTGAAGGGA  AGGCCCTGTA  CATTGATGCA  GAGGGAACAT  TCAGGCCACA  AAGGCTTCTC  480
481   CAGATAGCTG  ACAGGTTCGG  ATTGAATGGT  GCTGATGTAT  TAGAGAATGT  GGCTTATGCC  540
541   AGAGCTTATA  ATACTGATCA  TCAATCCAGA  CTTTTGCTGG  AGGCAGCTTC  CATGATGATA  600
601   GAGACTAGGT  TTGCTCTCAT  GATTGTAGAC  AGTGCGACAG  CTTTGTACAG  AACTGATTTC  660
661   TCAGGTCGAG  GGGAGCTCTC  AGCGAGGCAA  ATGCACATGG  CTAAGTTTCT  GAGGAGCCTT  720
721   CAGAAGTTAG  CTGATGAGTT  TGGAGTGGCT  GTGGTTATCA  CTAATCAAGT  AGTGGCACAA  780
781   GTGGATGGTT  CAGCTATGTT  TGCTGGGCCA  CAGATCAAAC  CCATCGGTGG  AAATATCATG  840
841   GCTCATGCTT  CCACGACAAG  GCTTGCTCTT  CGCAAGGGAA  GAGGGGAAGA  GCGAATCTGT  900
901   AAAGTGATAA  GCTCTCCATG  CTTGGCTGAA  GCCGAAGCAA  GGTTTCAGAT  AGCATCTGAA  960
961   GGCGTTGCAG  ATGTCAAGGA  TTGA  984

▼ KEYWORD

ID
Family
ATP-binding
Complete proteome
DNA damage
DNA recombination
DNA repair
DNA-binding
Nucleotide-binding
Nucleus
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Nucleus
Molecular Function
ATP binding
Molecular Function
DNA-dependent ATPase activity
Molecular Function
Double-stranded DNA binding
Molecular Function
Recombinase activity
Molecular Function
Single-stranded DNA binding
Biological Process
Double-strand break repair via homologous recombination
Biological Process
Mitotic recombination-dependent replication fork processing

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Orni-0346Oryza nivara97.470.0 626
LLPS-Orb-0968Oryza barthii97.470.0 626
LLPS-Orgl-1378Oryza glumaepatula97.470.0 626
LLPS-Orm-1476Oryza meridionalis97.470.0 625
LLPS-Orr-0589Oryza rufipogon97.470.0 626
LLPS-Ori-0868Oryza indica96.270.0 628
LLPS-Ors-0561Oryza sativa96.270.0 628
LLPS-Sei-0805Setaria italica94.70.0 619
LLPS-Orbr-1581Oryza brachyantha94.410.0 621
LLPS-Brd-2104Brachypodium distachyon93.770.0 616
LLPS-Sob-0629Sorghum bicolor93.770.0 615
LLPS-Zem-1050Zea mays91.90.0 606
LLPS-Org-0387Oryza glaberrima91.560.0 595
LLPS-Lep-0045Leersia perrieri91.080.0 584
LLPS-Amt-0464Amborella trichopoda90.650.0 600
LLPS-Cus-0879Cucumis sativus90.340.0 599
LLPS-Gor-0244Gossypium raimondii90.340.0 597
LLPS-Tra-1763Triticum aestivum90.310.0 595
LLPS-Coc-1076Corchorus capsularis90.310.0 594
LLPS-Mae-1281Manihot esculenta90.030.0 597
LLPS-Viv-1113Vitis vinifera90.030.0 599
LLPS-Hea-1054Helianthus annuus90.00.0 595
LLPS-Hov-0673Hordeum vulgare89.690.0 591
LLPS-Nia-1356Nicotiana attenuata89.10.0 593
LLPS-Prp-0255Prunus persica89.10.0 594
LLPS-Mua-0989Musa acuminata88.540.0 565
LLPS-Met-1439Medicago truncatula88.160.0 588
LLPS-Via-1323Vigna angularis88.160.0 592
LLPS-Phv-1803Phaseolus vulgaris88.160.0 588
LLPS-Art-2234Arabidopsis thaliana87.540.0 585
LLPS-Brr-0279Brassica rapa87.540.0 586
LLPS-Bro-1544Brassica oleracea87.540.0 586
LLPS-Thc-0045Theobroma cacao86.830.0 587
LLPS-Vir-0647Vigna radiata86.671e-148 439
LLPS-Brn-0477Brassica napus86.130.0 559
LLPS-Sol-2208Solanum lycopersicum84.910.0 585
LLPS-Pot-0303Populus trichocarpa84.50.0 563
LLPS-Dac-0824Daucus carota80.410.0 564
LLPS-Php-0500Physcomitrella patens75.940.0 526
LLPS-Anp-0940Anas platyrhynchos74.711e-147 424
LLPS-Aim-1407Ailuropoda melanoleuca74.338e-148 424
LLPS-Sah-0299Sarcophilus harrisii74.183e-97 292
LLPS-Pes-0183Pelodiscus sinensis69.914e-166 474
LLPS-Anc-1588Anolis carolinensis69.914e-166 473
LLPS-Chs-1202Chlorocebus sabaeus69.593e-167 476
LLPS-Meg-1764Meleagris gallopavo69.597e-164 468
LLPS-Gaga-2504Gallus gallus69.592e-165 472
LLPS-Nol-0176Nomascus leucogenys69.593e-167 476
LLPS-Tag-0126Taeniopygia guttata69.597e-165 470
LLPS-Poa-0639Pongo abelii69.593e-167 476
LLPS-Mam-1537Macaca mulatta69.593e-167 476
LLPS-Fud-2126Fukomys damarensis69.282e-166 474
LLPS-Caj-1810Callithrix jacchus69.285e-167 476
LLPS-Mum-2256Mus musculus69.282e-166 474
LLPS-Aon-1692Aotus nancymaae69.285e-167 476
LLPS-Sus-2233Sus scrofa69.285e-167 476
LLPS-Ran-1257Rattus norvegicus69.283e-166 474
LLPS-Ova-0042Ovis aries69.282e-166 474
LLPS-Dio-2170Dipodomys ordii69.282e-166 474
LLPS-Bot-1331Bos taurus69.282e-166 474
LLPS-Scf-2691Scleropages formosus69.287e-166 473
LLPS-Urm-2536Ursus maritimus69.282e-166 474
LLPS-Fec-2852Felis catus69.282e-166 474
LLPS-Loa-1315Loxodonta africana69.282e-166 474
LLPS-Caf-0869Canis familiaris69.282e-166 474
LLPS-Cap-1639Cavia porcellus69.282e-166 474
LLPS-Xet-1829Xenopus tropicalis69.062e-163 467
LLPS-Icp-0931Ictalurus punctatus68.979e-165 471
LLPS-Mod-0210Monodelphis domestica68.976e-166 473
LLPS-Eqc-0952Equus caballus68.973e-166 474
LLPS-Orc-0101Oryctolagus cuniculus68.651e-165 472
LLPS-Dar-1797Danio rerio68.656e-165 471
LLPS-Scm-3837Scophthalmus maximus68.651e-163 467
LLPS-Pof-0747Poecilia formosa68.542e-165 472
LLPS-Leo-3073Lepisosteus oculatus68.441e-161 462
LLPS-Orn-0144Oreochromis niloticus68.442e-164 469
LLPS-Orl-1751Oryzias latipes68.347e-163 468
LLPS-Tar-0893Takifugu rubripes68.342e-163 467
LLPS-Xim-1742Xiphophorus maculatus68.227e-165 470
LLPS-Ten-2068Tetraodon nigroviridis68.129e-162 462
LLPS-Asm-1642Astyanax mexicanus68.032e-163 467
LLPS-Gaa-1567Gasterosteus aculeatus68.031e-162 465
LLPS-Gas-0290Galdieria sulphuraria66.141e-155 448
LLPS-Scp-0055Schizosaccharomyces pombe66.142e-158 455
LLPS-Spr-0661Sporisorium reilianum66.142e-155 447
LLPS-Chr-0041Chlamydomonas reinhardtii65.621e-145 422
LLPS-Usm-0658Ustilago maydis65.529e-156 447
LLPS-Scj-0347Schizosaccharomyces japonicus65.223e-156 450
LLPS-Asg-1051Ashbya gossypii65.191e-139 408
LLPS-Sac-1028Saccharomyces cerevisiae65.192e-138 405
LLPS-Rhb-3015Rhinopithecus bieti65.052e-146 424
LLPS-Miv-1138Microbotryum violaceum64.891e-149 432
LLPS-Mup-0160Mustela putorius furo64.693e-147 426
LLPS-Yal-0630Yarrowia lipolytica64.584e-147 425
LLPS-Otg-1308Otolemur garnettii64.586e-149 430
LLPS-Lem-0187Leptosphaeria maculans64.312e-151 436
LLPS-Lac-3436Latimeria chalumnae64.267e-149 430
LLPS-Abg-0004Absidia glauca64.172e-145 421
LLPS-Fuo-0637Fusarium oxysporum64.156e-146 422
LLPS-Gog-2953Gorilla gorilla64.066e-145 420
LLPS-Maf-1412Macaca fascicularis64.062e-144 418
LLPS-Mal-0702Mandrillus leucophaeus64.066e-144 417
LLPS-Pap-2883Pan paniscus64.063e-145 421
LLPS-Pat-3187Pan troglodytes64.069e-145 419
LLPS-Hos-0179Homo sapiens64.062e-145 421
LLPS-Blg-0137Blumeria graminis63.984e-148 428
LLPS-Ast-1271Aspergillus terreus63.982e-149 431
LLPS-Fuv-0487Fusarium verticillioides63.842e-145 421
LLPS-Nec-0357Neurospora crassa63.846e-146 423
LLPS-Paa-0451Papio anubis63.754e-143 415
LLPS-Pyt-1474Pyrenophora teres63.693e-150 433
LLPS-Pytr-1374Pyrenophora triticirepentis63.693e-150 433
LLPS-Crn-0871Cryptococcus neoformans63.523e-139 405
LLPS-Map-0007Magnaporthe poae63.351e-145 422
LLPS-Asc-1540Aspergillus clavatus63.354e-148 428
LLPS-Asf-1520Aspergillus flavus63.352e-147 427
LLPS-Aso-0730Aspergillus oryzae63.352e-147 427
LLPS-Cog-1113Colletotrichum gloeosporioides63.354e-146 423
LLPS-Beb-0886Beauveria bassiana63.353e-145 421
LLPS-Coo-0828Colletotrichum orbiculare63.043e-146 424
LLPS-Asn-0406Aspergillus nidulans63.041e-147 427
LLPS-Mao-0993Magnaporthe oryzae63.042e-144 419
LLPS-Gag-0894Gaeumannomyces graminis63.042e-145 422
LLPS-Nef-0743Neosartorya fischeri63.041e-147 427
LLPS-Ved-0295Verticillium dahliae63.041e-145 422
LLPS-Asfu-0380Aspergillus fumigatus63.041e-147 427
LLPS-Chc-0721Chondrus crispus63.018e-146 422
LLPS-Cogr-1167Colletotrichum graminicola62.732e-145 421
LLPS-Kop-1215Komagataella pastoris62.78e-149 430
LLPS-Cas-0856Carlito syrichta62.53e-142 413
LLPS-Scc-0715Schizosaccharomyces cryophilus62.424e-147 426
LLPS-Cis-1251Ciona savignyi62.387e-146 422
LLPS-Myl-2666Myotis lucifugus61.822e-142 414
LLPS-Trv-0441Trichoderma virens61.822e-145 421
LLPS-Cym-0733Cyanidioschyzon merolae61.688e-135 400
LLPS-Osl-0652Ostreococcus lucimarinus60.762e-137 400
LLPS-Cea-1224Cercocebus atys58.526e-120 355
LLPS-Drm-0946Drosophila melanogaster58.133e-129 380
LLPS-Man-0009Macaca nemestrina57.598e-117 348
LLPS-Put-0279Puccinia triticina57.054e-128 379
LLPS-Pug-0396Puccinia graminis56.744e-128 377
LLPS-Cae-1748Caenorhabditis elegans53.82e-120 359
LLPS-Ora-2636Ornithorhynchus anatinus52.112e-85 267
LLPS-Sot-0776Solanum tuberosum50.173e-95 293
LLPS-Tut-0459Tursiops truncatus48.268e-96 294
LLPS-Ict-4253Ictidomys tridecemlineatus47.951e-95 294
LLPS-Fia-1219Ficedula albicollis47.631e-94 291
LLPS-Scs-0403Sclerotinia sclerotiorum45.347e-87 271