• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Cym-0733
CYME_CMR053C

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: DNA repair protein RAD51 homolog
Gene Name: CYME_CMR053C
Ensembl Gene: CMR053C
Ensembl Protein: CMR053CT
Organism: Cyanidioschyzon merolae
Taxa ID: 280699
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
DNA damage fociPredicted from orthologs(View)

▼ FUNCTION

Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblCMR053CTCMR053CT
UniProtM1UW54, M1UW54_CYAM1
GeneBankAP006500BAM82331.1
RefSeqXM_005538310.1XP_005538367.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MECWGARHRR  AQRARARLCF  ALRCWRRRRA  AAGNVPQGRV  FTRRSSGRPG  DTGSHASYHD  60
61    LGANASSRII  PGALHERWHP  MDRVRSSDSA  RVRTSAAATG  AVAASEIARC  RGNSNWHRAG  120
121   KQRAHAPYDL  AALERLPRVC  VCVCVCVCVS  AGTLLGEPMP  RRVEATATVE  ALEEDLVEKN  180
181   EQTVAAGPTP  LAALEGVQGI  TASDLKKLRE  EGGVHSVEAV  VYLTMKQLTS  IKGVSEAKAE  240
241   KLKSAAAQLV  MAGFTTATEV  HRIRKDLVFL  TTGSKELDAL  LQGGIETGSI  TELFGEFRTG  300
301   KSQLCHTLCV  TCQMPVAEGG  AEGKALYIDT  EGTFRPERIV  QIAERFQLDP  QDVLDNVAFA  360
361   RAYNTDHQME  LLMQAAGLMS  ESRYALVVVD  SATALYRTDY  SGRGELAARQ  QHMARFLRAL  420
421   QRLADEFGVA  VVITNQVVAK  PDAMMFADPR  VPIGGNIIAH  ACQTRLYFRK  GRGENRICKI  480
481   YDSPSLPEAE  ASFAITEGGV  ADPVD  505
Nucleotide CDS Sequence (FASTA)
1     ATGGAATGTT  GGGGGGCACG  GCACCGCAGG  GCGCAGCGTG  CCCGTGCGCG  TCTGTGTTTC  60
61    GCGTTGAGGT  GCTGGCGTCG  TCGACGCGCA  GCTGCAGGTA  ACGTGCCGCA  GGGACGGGTT  120
121   TTTACCCGCA  GATCATCTGG  ACGACCTGGA  GATACCGGAT  CACACGCCAG  CTATCATGAT  180
181   CTAGGAGCGA  ACGCGTCATC  CCGCATCATT  CCGGGGGCGC  TCCACGAGCG  ATGGCACCCT  240
241   ATGGATCGCG  TGCGATCCTC  GGATTCCGCT  CGTGTACGTA  CGAGCGCCGC  CGCCACAGGC  300
301   GCCGTCGCAG  CGTCAGAGAT  CGCGCGGTGC  CGCGGGAATT  CGAACTGGCA  TCGGGCTGGG  360
361   AAGCAGCGCG  CGCACGCGCC  GTACGACCTC  GCGGCACTGG  AGCGTCTACC  GCGCGTGTGC  420
421   GTGTGCGTGT  GCGTCTGCGT  GTGCGTGTCA  GCGGGAACGT  TACTCGGAGA  ACCCATGCCT  480
481   CGTCGTGTGG  AAGCTACTGC  AACAGTTGAG  GCCTTGGAGG  AAGATCTAGT  GGAGAAGAAT  540
541   GAACAAACGG  TTGCTGCGGG  TCCGACACCC  CTCGCGGCGC  TGGAAGGCGT  GCAGGGTATC  600
601   ACCGCCTCTG  ACTTGAAAAA  GCTACGAGAG  GAGGGCGGTG  TGCACAGTGT  CGAGGCTGTC  660
661   GTCTACCTGA  CCATGAAGCA  ACTCACCTCT  ATCAAAGGCG  TTAGCGAAGC  GAAAGCGGAG  720
721   AAGCTGAAAT  CTGCCGCAGC  CCAGTTGGTG  ATGGCTGGTT  TCACCACCGC  CACGGAAGTG  780
781   CATCGAATAC  GAAAAGATCT  GGTTTTTCTG  ACGACCGGCA  GTAAGGAGCT  CGACGCGTTG  840
841   CTCCAAGGCG  GTATTGAAAC  AGGGAGTATT  ACGGAGCTGT  TCGGGGAGTT  TCGCACCGGC  900
901   AAGTCACAGC  TGTGTCACAC  CTTGTGCGTC  ACCTGCCAGA  TGCCTGTCGC  CGAGGGTGGC  960
961   GCCGAAGGCA  AGGCCCTCTA  CATCGATACC  GAGGGCACCT  TCCGCCCCGA  GCGCATCGTA  1020
1021  CAGATTGCGG  AGCGTTTCCA  GCTGGATCCG  CAAGATGTTC  TGGATAACGT  TGCATTTGCC  1080
1081  AGAGCGTATA  ATACCGACCA  CCAGATGGAA  TTACTCATGC  AGGCAGCGGG  CCTGATGAGC  1140
1141  GAAAGCCGTT  ACGCCCTCGT  CGTTGTTGAC  TCGGCCACTG  CGCTCTACCG  CACGGACTAC  1200
1201  TCTGGGCGTG  GCGAGCTTGC  CGCCCGTCAG  CAACACATGG  CTCGATTCCT  GCGCGCCCTC  1260
1261  CAGCGCCTCG  CTGATGAATT  CGGCGTAGCG  GTCGTCATAA  CAAACCAGGT  GGTCGCGAAA  1320
1321  CCCGACGCCA  TGATGTTTGC  TGATCCGCGC  GTTCCGATTG  GTGGCAATAT  CATTGCTCAT  1380
1381  GCGTGCCAAA  CTCGTCTGTA  TTTTCGCAAG  GGTCGCGGTG  AGAACCGTAT  CTGCAAGATC  1440
1441  TACGATTCTC  CATCGCTCCC  TGAGGCCGAA  GCGAGCTTTG  CTATCACCGA  GGGAGGTGTT  1500
1501  GCCGATCCAG  TGGAC  1515

▼ KEYWORD

ID
Family
ATP-binding
Coiled coil
Complete proteome
DNA damage
DNA recombination
DNA repair
DNA-binding
Nucleotide-binding
Nucleus
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Nucleus
Molecular Function
ATP binding
Molecular Function
DNA-dependent ATPase activity
Molecular Function
Double-stranded DNA binding
Molecular Function
Recombinase activity
Molecular Function
Single-stranded DNA binding
Biological Process
Double-strand break repair via homologous recombination
Biological Process
Mitotic recombination-dependent replication fork processing

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Anp-0940Anas platyrhynchos74.231e-135 400
LLPS-Sah-0299Sarcophilus harrisii74.182e-89 278
LLPS-Aim-1407Ailuropoda melanoleuca73.462e-134 397
LLPS-Leo-3073Lepisosteus oculatus70.51e-146 431
LLPS-Orc-0101Oryctolagus cuniculus70.444e-149 437
LLPS-Gaga-2504Gallus gallus70.446e-149 437
LLPS-Pes-0183Pelodiscus sinensis70.41e-150 441
LLPS-Fec-2852Felis catus70.43e-150 440
LLPS-Tag-0126Taeniopygia guttata70.42e-149 438
LLPS-Anc-1588Anolis carolinensis70.44e-150 440
LLPS-Nol-0176Nomascus leucogenys70.42e-150 441
LLPS-Poa-0639Pongo abelii70.42e-150 441
LLPS-Caf-0869Canis familiaris70.43e-150 440
LLPS-Mam-1537Macaca mulatta70.42e-150 441
LLPS-Caj-1810Callithrix jacchus70.43e-150 441
LLPS-Chs-1202Chlorocebus sabaeus70.42e-150 441
LLPS-Aon-1692Aotus nancymaae70.43e-150 441
LLPS-Xet-1829Xenopus tropicalis70.196e-148 434
LLPS-Meg-1764Meleagris gallopavo70.136e-147 432
LLPS-Urm-2536Ursus maritimus70.098e-150 439
LLPS-Loa-1315Loxodonta africana70.099e-150 439
LLPS-Eqc-0952Equus caballus70.091e-149 439
LLPS-Cap-1639Cavia porcellus70.098e-150 439
LLPS-Fud-2126Fukomys damarensis70.099e-150 439
LLPS-Mum-2256Mus musculus70.091e-149 439
LLPS-Sus-2233Sus scrofa70.093e-150 440
LLPS-Gas-0290Galdieria sulphuraria70.094e-154 451
LLPS-Ran-1257Rattus norvegicus70.091e-149 439
LLPS-Ova-0042Ovis aries70.098e-150 439
LLPS-Bot-1331Bos taurus70.098e-150 439
LLPS-Scf-2691Scleropages formosus70.099e-149 437
LLPS-Dio-2170Dipodomys ordii70.099e-150 439
LLPS-Orn-0144Oreochromis niloticus69.782e-148 436
LLPS-Mod-0210Monodelphis domestica69.782e-149 438
LLPS-Asm-1642Astyanax mexicanus69.789e-149 437
LLPS-Xim-1742Xiphophorus maculatus69.784e-149 437
LLPS-Pof-0747Poecilia formosa69.472e-148 436
LLPS-Dar-1797Danio rerio69.473e-149 438
LLPS-Orl-1751Oryzias latipes69.475e-148 437
LLPS-Gaa-1567Gasterosteus aculeatus69.161e-147 434
LLPS-Icp-0931Ictalurus punctatus68.981e-149 440
LLPS-Ten-2068Tetraodon nigroviridis68.946e-145 427
LLPS-Scm-3837Scophthalmus maximus68.586e-149 437
LLPS-Tar-0893Takifugu rubripes68.52e-148 436
LLPS-Scj-0347Schizosaccharomyces japonicus67.083e-143 424
LLPS-Scp-0055Schizosaccharomyces pombe67.072e-147 434
LLPS-Chc-0721Chondrus crispus66.971e-147 434
LLPS-Sac-1028Saccharomyces cerevisiae66.253e-125 379
LLPS-Rhb-3015Rhinopithecus bieti66.117e-127 380
LLPS-Asg-1051Ashbya gossypii65.854e-127 383
LLPS-Otg-1308Otolemur garnettii65.735e-134 399
LLPS-Mup-0160Mustela putorius furo65.536e-131 391
LLPS-Usm-0658Ustilago maydis65.333e-136 404
LLPS-Lac-3436Latimeria chalumnae65.111e-132 395
LLPS-Ast-1271Aspergillus terreus65.01e-140 416
LLPS-Abg-0004Absidia glauca64.912e-141 417
LLPS-Crn-0871Cryptococcus neoformans64.52e-124 375
LLPS-Spr-0661Sporisorium reilianum64.294e-134 400
LLPS-Maf-1412Macaca fascicularis64.295e-130 389
LLPS-Mal-0702Mandrillus leucophaeus64.291e-129 387
LLPS-Sei-0805Setaria italica64.24e-137 407
LLPS-Asf-1520Aspergillus flavus64.064e-139 412
LLPS-Blg-0137Blumeria graminis64.068e-140 414
LLPS-Aso-0730Aspergillus oryzae64.064e-139 412
LLPS-Paa-0451Papio anubis63.982e-128 385
LLPS-Orbr-1581Oryza brachyantha63.862e-136 405
LLPS-Ors-0561Oryza sativa63.861e-135 403
LLPS-Ori-0868Oryza indica63.861e-135 403
LLPS-Nef-0743Neosartorya fischeri63.755e-139 412
LLPS-Beb-0886Beauveria bassiana63.754e-137 407
LLPS-Asfu-0380Aspergillus fumigatus63.756e-139 412
LLPS-Map-0007Magnaporthe poae63.753e-138 410
LLPS-Thc-0045Theobroma cacao63.751e-131 394
LLPS-Asc-1540Aspergillus clavatus63.756e-139 412
LLPS-Pytr-1374Pyrenophora triticirepentis63.661e-142 421
LLPS-Pyt-1474Pyrenophora teres63.661e-142 421
LLPS-Pat-3187Pan troglodytes63.646e-130 389
LLPS-Tra-1763Triticum aestivum63.553e-134 399
LLPS-Hov-0673Hordeum vulgare63.551e-132 396
LLPS-Ved-0295Verticillium dahliae63.448e-139 412
LLPS-Mao-0993Magnaporthe oryzae63.441e-137 409
LLPS-Zem-1050Zea mays63.419e-137 406
LLPS-Scc-0715Schizosaccharomyces cryophilus63.416e-134 399
LLPS-Gog-2953Gorilla gorilla63.33e-129 387
LLPS-Yal-0630Yarrowia lipolytica63.31e-136 405
LLPS-Lem-0187Leptosphaeria maculans63.281e-143 424
LLPS-Gor-0244Gossypium raimondii63.243e-134 399
LLPS-Orr-0589Oryza rufipogon63.243e-133 397
LLPS-Orm-1476Oryza meridionalis63.243e-133 397
LLPS-Orni-0346Oryza nivara63.243e-133 397
LLPS-Orb-0968Oryza barthii63.243e-133 397
LLPS-Orgl-1378Oryza glumaepatula63.243e-133 397
LLPS-Asn-0406Aspergillus nidulans63.125e-138 409
LLPS-Gag-0894Gaeumannomyces graminis63.124e-137 407
LLPS-Sob-0629Sorghum bicolor63.112e-136 405
LLPS-Brd-2104Brachypodium distachyon63.113e-137 407
LLPS-Pap-2883Pan paniscus63.061e-129 387
LLPS-Hos-0179Homo sapiens63.067e-130 388
LLPS-Kop-1215Komagataella pastoris63.017e-136 404
LLPS-Prp-0255Prunus persica62.931e-133 398
LLPS-Cogr-1167Colletotrichum graminicola62.813e-137 407
LLPS-Org-0387Oryza glaberrima62.814e-132 394
LLPS-Fuo-0637Fusarium oxysporum62.811e-136 406
LLPS-Fuv-0487Fusarium verticillioides62.812e-136 405
LLPS-Nec-0357Neurospora crassa62.814e-137 407
LLPS-Phv-1803Phaseolus vulgaris62.621e-133 398
LLPS-Coc-1076Corchorus capsularis62.622e-133 397
LLPS-Cas-0856Carlito syrichta62.575e-129 386
LLPS-Amt-0464Amborella trichopoda62.311e-133 398
LLPS-Mae-1281Manihot esculenta62.314e-132 394
LLPS-Hea-1054Helianthus annuus62.319e-133 396
LLPS-Cus-0879Cucumis sativus62.312e-132 395
LLPS-Php-0500Physcomitrella patens62.153e-132 394
LLPS-Glm-2885Glycine max61.995e-133 397
LLPS-Via-1323Vigna angularis61.996e-134 399
LLPS-Trv-0441Trichoderma virens61.895e-135 402
LLPS-Orp-1774Oryza punctata61.681e-133 397
LLPS-Chr-0041Chlamydomonas reinhardtii61.683e-127 382
LLPS-Myl-2666Myotis lucifugus61.544e-128 384
LLPS-Coo-0828Colletotrichum orbiculare61.523e-138 410
LLPS-Viv-1113Vitis vinifera61.372e-131 392
LLPS-Lep-0045Leersia perrieri61.379e-129 385
LLPS-Vir-0647Vigna radiata61.222e-95 308
LLPS-Nia-1356Nicotiana attenuata61.143e-133 397
LLPS-Cog-1113Colletotrichum gloeosporioides60.961e-138 411
LLPS-Osl-0652Ostreococcus lucimarinus60.879e-129 385
LLPS-Art-2234Arabidopsis thaliana60.611e-133 398
LLPS-Brr-0279Brassica rapa60.611e-133 398
LLPS-Bro-1544Brassica oleracea60.611e-133 398
LLPS-Met-1439Medicago truncatula60.618e-134 398
LLPS-Drm-0946Drosophila melanogaster60.065e-124 373
LLPS-Mua-0989Musa acuminata59.515e-124 373
LLPS-Put-0279Puccinia triticina58.843e-123 374
LLPS-Miv-1138Microbotryum violaceum58.721e-121 367
LLPS-Cis-1251Ciona savignyi58.637e-124 373
LLPS-Pug-0396Puccinia graminis58.23e-121 366
LLPS-Dac-0824Daucus carota57.594e-128 385
LLPS-Brn-0477Brassica napus57.582e-127 381
LLPS-Man-0009Macaca nemestrina57.363e-104 322
LLPS-Ora-2636Ornithorhynchus anatinus56.592e-92 292
LLPS-Cae-1748Caenorhabditis elegans56.426e-111 342
LLPS-Cea-1224Cercocebus atys56.391e-102 317
LLPS-Pot-0303Populus trichocarpa55.232e-121 367
LLPS-Sol-2208Solanum lycopersicum54.88e-124 374
LLPS-Tut-0459Tursiops truncatus53.44e-99 309
LLPS-Ict-4253Ictidomys tridecemlineatus53.075e-99 309
LLPS-Fia-1219Ficedula albicollis52.753e-98 307
LLPS-Sot-0776Solanum tuberosum51.164e-90 286
LLPS-Scs-0403Sclerotinia sclerotiorum49.533e-92 291