• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Asf-1520
AFLA_069300

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: DNA repair protein RAD51 homolog
Gene Name: AFLA_069300
Ensembl Gene: AFLA_069300
Ensembl Protein: EED50108
Organism: Aspergillus flavus
Taxa ID: 332952
LLPS Type: Client


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
DNA damage fociPredicted from orthologs(View)

▼ FUNCTION

Required both for recombination and for the repair of DNA damage caused by X-rays.

▼ CROSS REFERENCE

DatabaseNucleotide IDProtein ID
EnsemblEED50108EED50108
UniProtB8NJX0, B8NJX0_ASPFN
GeneBankEQ963479EED50108.1
RefSeqXM_002380448.1XP_002380489.1

▼ SEQUENCE

Protein Sequence (FASTA)
1     MTADMDTQNE  YDDSGLPGPG  APTPLSALEG  VAGLTGRDIK  LFVDAGYHTV  ESIAYTPKRL  60
61    LEQIKGISEQ  KATKVLVEAA  KLVPMGFTTA  TEMHARRSEL  ISITTGSKQL  DTLLGGGIET  120
121   GSITEIFGEF  RTGKSQICHT  LAVTCQLPFD  MGGGEGKCLY  IDTEGTFRPV  RLLAVAQRYG  180
181   LVGEEVLDNV  AYARAYNSDH  QLQLLNQASQ  MMCETRFSLL  VVDSATALYR  TDFNGRGELS  240
241   TRQTHLAKFM  RTLQRLADEF  GIAVVITNQV  VAQVDGGPSA  MFNPDPKKPI  GGNIIAHAST  300
301   TRLSLKKGRG  ETRVCKIYDS  PCLPESDCLF  AINEDGIGDP  SPKDLENN  348
Nucleotide CDS Sequence (FASTA)
1     ATGACGGCGG  ATATGGATAC  TCAGAATGAA  TACGATGATA  GTGGACTTCC  CGGGCCTGGA  60
61    GCGCCCACGC  CACTTTCAGC  TTTAGAAGGT  GTTGCGGGAT  TAACGGGAAG  AGATATCAAA  120
121   TTGTTTGTCG  ATGCCGGCTA  TCACACTGTC  GAATCAATTG  CGTATACACC  GAAACGTTTA  180
181   CTGGAACAAA  TCAAAGGTAT  ATCGGAGCAG  AAGGCCACCA  AGGTTTTGGT  TGAAGCTGCC  240
241   AAGCTTGTGC  CAATGGGTTT  CACGACTGCA  ACAGAAATGC  ATGCACGTCG  AAGTGAGCTC  300
301   ATATCGATCA  CGACAGGATC  CAAGCAACTA  GATACTCTCC  TAGGCGGTGG  TATAGAAACG  360
361   GGATCTATTA  CCGAGATATT  CGGAGAATTC  AGGACAGGTA  AAAGTCAAAT  TTGCCATACG  420
421   CTTGCAGTGA  CTTGCCAGCT  GCCATTCGAC  ATGGGTGGTG  GGGAAGGGAA  GTGTCTTTAT  480
481   ATTGATACTG  AAGGGACATT  TCGACCGGTC  CGTCTGTTGG  CAGTTGCTCA  AAGATACGGA  540
541   CTTGTTGGCG  AAGAGGTACT  CGATAATGTG  GCCTATGCCC  GCGCTTATAA  CTCGGATCAC  600
601   CAGCTCCAGC  TGCTGAACCA  GGCGTCTCAA  ATGATGTGCG  AAACTCGTTT  CTCACTTCTT  660
661   GTCGTCGACT  CTGCTACAGC  GCTATATCGG  ACAGATTTTA  ACGGCCGTGG  TGAACTATCG  720
721   ACTCGACAAA  CACATCTCGC  TAAATTCATG  CGTACCTTGC  AGCGCTTGGC  GGATGAATTT  780
781   GGTATTGCCG  TCGTCATCAC  CAACCAGGTC  GTCGCCCAGG  TCGACGGCGG  TCCGAGTGCA  840
841   ATGTTCAACC  CAGACCCCAA  GAAGCCAATC  GGTGGAAACA  TTATCGCACA  CGCCAGCACG  900
901   ACCAGGCTGA  GTCTGAAAAA  GGGGAGAGGA  GAGACCCGAG  TGTGCAAGAT  CTATGACAGT  960
961   CCCTGTCTGC  CCGAGAGTGA  CTGTCTTTTT  GCCATCAATG  AAGATGGTAT  TGGGGATCCT  1020
1021  AGCCCCAAGG  ACTTGGAAAA  TAACTGA  1047

▼ KEYWORD

ID
Family
ATP-binding
Complete proteome
DNA damage
DNA recombination
DNA repair
DNA-binding
Nucleotide-binding
Nucleus
Reference proteome

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Chromosome, centromeric region
Cellular Component
Nucleus
Cellular Component
Site of double-strand break
Molecular Function
ATP binding
Molecular Function
DNA-dependent ATPase activity
Molecular Function
Double-stranded DNA binding
Molecular Function
Identical protein binding
Molecular Function
Recombinase activity
Molecular Function
Single-stranded DNA binding
Molecular Function
Swi5-Sfr1 complex binding
Biological Process
Chromatin silencing at centromere
Biological Process
Double-strand break repair involved in meiotic recombination
Biological Process
Double-strand break repair via homologous recombination
Biological Process
Interstrand cross-link repair
Biological Process
Mating type switching
Biological Process
Mitotic recombination
Biological Process
Mitotic recombination-dependent replication fork processing
Biological Process
Protein homooligomerization
Biological Process
Regulation of DNA recombination at centromere
Biological Process
Strand invasion
Biological Process
Telomere maintenance

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Aso-0730Aspergillus oryzae100.00.0 676
LLPS-Nef-0743Neosartorya fischeri97.990.0 666
LLPS-Asfu-0380Aspergillus fumigatus97.70.0 665
LLPS-Asn-0406Aspergillus nidulans97.70.0 665
LLPS-Ast-1271Aspergillus terreus97.130.0 660
LLPS-Asc-1540Aspergillus clavatus97.130.0 655
LLPS-Cogr-1167Colletotrichum graminicola90.330.0 588
LLPS-Blg-0137Blumeria graminis89.80.0 605
LLPS-Nec-0357Neurospora crassa89.440.0 603
LLPS-Pytr-1374Pyrenophora triticirepentis89.150.0 597
LLPS-Pyt-1474Pyrenophora teres89.150.0 597
LLPS-Cog-1113Colletotrichum gloeosporioides88.920.0 600
LLPS-Ved-0295Verticillium dahliae88.860.0 598
LLPS-Coo-0828Colletotrichum orbiculare88.720.0 593
LLPS-Lem-0187Leptosphaeria maculans88.270.0 592
LLPS-Fuv-0487Fusarium verticillioides88.110.0 573
LLPS-Fuo-0637Fusarium oxysporum87.80.0 571
LLPS-Mao-0993Magnaporthe oryzae87.760.0 592
LLPS-Map-0007Magnaporthe poae86.210.0 599
LLPS-Gag-0894Gaeumannomyces graminis85.80.0 591
LLPS-Trv-0441Trichoderma virens85.110.0 589
LLPS-Beb-0886Beauveria bassiana84.480.0 580
LLPS-Scj-0347Schizosaccharomyces japonicus80.83e-174 496
LLPS-Aim-1407Ailuropoda melanoleuca80.152e-141 409
LLPS-Anp-0940Anas platyrhynchos79.774e-141 408
LLPS-Scp-0055Schizosaccharomyces pombe78.932e-177 504
LLPS-Sah-0299Sarcophilus harrisii77.94e-101 303
LLPS-Kop-1215Komagataella pastoris76.785e-168 480
LLPS-Spr-0661Sporisorium reilianum76.187e-163 467
LLPS-Scc-0715Schizosaccharomyces cryophilus75.373e-164 470
LLPS-Pof-0747Poecilia formosa75.162e-162 465
LLPS-Cap-1639Cavia porcellus75.162e-162 465
LLPS-Yal-0630Yarrowia lipolytica75.162e-156 449
LLPS-Orl-1751Oryzias latipes75.167e-162 466
LLPS-Xim-1742Xiphophorus maculatus75.166e-163 466
LLPS-Scf-2691Scleropages formosus75.164e-163 467
LLPS-Dio-2170Dipodomys ordii75.162e-162 465
LLPS-Crn-0871Cryptococcus neoformans75.09e-152 438
LLPS-Usm-0658Ustilago maydis74.615e-160 459
LLPS-Orn-0144Oreochromis niloticus74.539e-162 463
LLPS-Tar-0893Takifugu rubripes74.538e-162 463
LLPS-Leo-3073Lepisosteus oculatus74.292e-158 455
LLPS-Dar-1797Danio rerio74.215e-162 464
LLPS-Icp-0931Ictalurus punctatus73.94e-161 463
LLPS-Asm-1642Astyanax mexicanus73.92e-161 462
LLPS-Gaa-1567Gasterosteus aculeatus73.99e-161 461
LLPS-Gaga-2504Gallus gallus72.41e-162 466
LLPS-Nol-0176Nomascus leucogenys72.271e-163 468
LLPS-Poa-0639Pongo abelii72.271e-163 468
LLPS-Mam-1537Macaca mulatta72.271e-163 468
LLPS-Caj-1810Callithrix jacchus72.271e-163 468
LLPS-Chs-1202Chlorocebus sabaeus72.271e-163 468
LLPS-Mum-2256Mus musculus72.272e-163 467
LLPS-Aon-1692Aotus nancymaae72.271e-163 468
LLPS-Ran-1257Rattus norvegicus72.271e-163 468
LLPS-Mod-0210Monodelphis domestica72.112e-161 462
LLPS-Orc-0101Oryctolagus cuniculus71.986e-163 466
LLPS-Fec-2852Felis catus71.989e-163 466
LLPS-Urm-2536Ursus maritimus71.988e-163 466
LLPS-Loa-1315Loxodonta africana71.986e-163 466
LLPS-Eqc-0952Equus caballus71.989e-163 466
LLPS-Caf-0869Canis familiaris71.988e-163 466
LLPS-Fud-2126Fukomys damarensis71.981e-162 466
LLPS-Ova-0042Ovis aries71.988e-163 466
LLPS-Bot-1331Bos taurus71.988e-163 466
LLPS-Scm-3837Scophthalmus maximus71.811e-162 466
LLPS-Meg-1764Meleagris gallopavo71.811e-160 461
LLPS-Sus-2233Sus scrofa71.681e-163 468
LLPS-Asg-1051Ashbya gossypii71.61e-145 424
LLPS-Pes-0183Pelodiscus sinensis71.514e-162 464
LLPS-Anc-1588Anolis carolinensis71.395e-162 464
LLPS-Tag-0126Taeniopygia guttata71.097e-162 464
LLPS-Ten-2068Tetraodon nigroviridis70.883e-160 459
LLPS-Xet-1829Xenopus tropicalis70.851e-159 458
LLPS-Abg-0004Absidia glauca69.824e-153 441
LLPS-Sac-1028Saccharomyces cerevisiae69.462e-145 424
LLPS-Lac-3436Latimeria chalumnae68.874e-152 439
LLPS-Rhb-3015Rhinopithecus bieti68.631e-138 405
LLPS-Miv-1138Microbotryum violaceum68.621e-144 420
LLPS-Php-0500Physcomitrella patens67.753e-137 401
LLPS-Otg-1308Otolemur garnettii67.261e-147 427
LLPS-Mup-0160Mustela putorius furo67.062e-143 417
LLPS-Chc-0721Chondrus crispus66.999e-136 397
LLPS-Thc-0045Theobroma cacao66.881e-137 403
LLPS-Gas-0290Galdieria sulphuraria66.771e-146 426
LLPS-Brd-2104Brachypodium distachyon65.725e-142 413
LLPS-Gor-0244Gossypium raimondii65.417e-138 403
LLPS-Viv-1113Vitis vinifera65.411e-138 405
LLPS-Coc-1076Corchorus capsularis65.413e-137 401
LLPS-Sei-0805Setaria italica65.413e-140 409
LLPS-Sob-0629Sorghum bicolor65.094e-140 408
LLPS-Zem-1050Zea mays65.094e-138 403
LLPS-Tra-1763Triticum aestivum65.091e-137 402
LLPS-Hov-0673Hordeum vulgare65.093e-136 399
LLPS-Orbr-1581Oryza brachyantha64.913e-141 411
LLPS-Ors-0561Oryza sativa64.914e-140 408
LLPS-Ori-0868Oryza indica64.914e-140 408
LLPS-Mae-1281Manihot esculenta64.784e-136 399
LLPS-Art-2234Arabidopsis thaliana64.782e-137 401
LLPS-Org-0387Oryza glaberrima64.783e-136 398
LLPS-Hea-1054Helianthus annuus64.784e-138 404
LLPS-Phv-1803Phaseolus vulgaris64.472e-137 402
LLPS-Brr-0279Brassica rapa64.473e-137 401
LLPS-Bro-1544Brassica oleracea64.473e-137 401
LLPS-Prp-0255Prunus persica64.471e-137 402
LLPS-Cus-0879Cucumis sativus64.473e-137 401
LLPS-Orm-1476Oryza meridionalis64.293e-136 398
LLPS-Orr-0589Oryza rufipogon64.293e-136 398
LLPS-Orni-0346Oryza nivara64.292e-136 398
LLPS-Orb-0968Oryza barthii64.292e-136 398
LLPS-Orgl-1378Oryza glumaepatula64.292e-136 398
LLPS-Amt-0464Amborella trichopoda64.151e-136 399
LLPS-Glm-2885Glycine max64.153e-137 401
LLPS-Cis-1251Ciona savignyi64.153e-139 406
LLPS-Pap-2883Pan paniscus64.125e-138 403
LLPS-Pat-3187Pan troglodytes64.126e-138 403
LLPS-Gog-2953Gorilla gorilla64.126e-138 403
LLPS-Cym-0733Cyanidioschyzon merolae64.062e-130 390
LLPS-Orp-1774Oryza punctata63.351e-133 392
LLPS-Pug-0396Puccinia graminis62.73e-128 378
LLPS-Lep-0045Leersia perrieri62.583e-126 373
LLPS-Met-1439Medicago truncatula62.462e-137 401
LLPS-Drm-0946Drosophila melanogaster62.462e-124 369
LLPS-Nia-1356Nicotiana attenuata62.133e-136 399
LLPS-Myl-2666Myotis lucifugus62.014e-134 393
LLPS-Mua-0989Musa acuminata61.958e-123 364
LLPS-Hos-0179Homo sapiens61.827e-138 403
LLPS-Maf-1412Macaca fascicularis61.714e-139 406
LLPS-Paa-0451Papio anubis61.711e-138 404
LLPS-Mal-0702Mandrillus leucophaeus61.436e-138 403
LLPS-Cas-0856Carlito syrichta61.324e-138 404
LLPS-Brn-0477Brassica napus61.133e-123 365
LLPS-Dac-0824Daucus carota60.887e-130 383
LLPS-Chr-0041Chlamydomonas reinhardtii60.675e-116 347
LLPS-Vir-0647Vigna radiata60.612e-96 305
LLPS-Put-0279Puccinia triticina60.474e-129 383
LLPS-Via-1323Vigna angularis60.471e-138 404
LLPS-Cae-1748Caenorhabditis elegans59.61e-116 350
LLPS-Osl-0652Ostreococcus lucimarinus59.314e-117 350
LLPS-Tum-1144Tuber melanosporum58.943e-126 370
LLPS-Sol-2208Solanum lycopersicum58.381e-123 367
LLPS-Pot-0303Populus trichocarpa56.92e-124 369
LLPS-Cea-1224Cercocebus atys56.271e-123 365
LLPS-Man-0009Macaca nemestrina54.243e-107 324
LLPS-Ora-2636Ornithorhynchus anatinus53.852e-79 253
LLPS-Fia-1219Ficedula albicollis51.788e-90 280
LLPS-Tut-0459Tursiops truncatus51.466e-90 280
LLPS-Ict-4253Ictidomys tridecemlineatus51.137e-90 280
LLPS-Sot-0776Solanum tuberosum51.061e-80 256
LLPS-Scs-0403Sclerotinia sclerotiorum49.224e-83 262