• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Orl-0368
lsm1

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: U6 snRNA-associated Sm-like protein LSm1
Gene Name: lsm1, LSM1
Ensembl Gene: ENSORLG00000030288.1
Ensembl Protein: ENSORLP00000045782.1
Organism: Oryzias latipes
Taxa ID: 8090
LLPS Type: LLPS regulator


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
P-body, Stress granulePredicted from orthologs(View)

▼ FUNCTION

Probably involved with other LSm subunits in the general process of degradation of mRNAs.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MNYVPGTASL  IDDIDKKHLV  LLRDGRTLIG  YLRSIDQFAN  LVFHQTVERI  HVGKKFGDIP  60
61    RGIFIVRGEN  VVLLGEIDLD  KPCDTVLQQV  SIEEILEEQR  LQQQAKQETE  KVKMQALKDR  120
121   GLSIPKADNL  DEY  133
Nucleotide CDS Sequence (FASTA)
1     ATGAATTACG  TACCAGGGAC  GGCCAGTCTC  ATTGACGATA  TTGACAAAAA  GCACTTGGTC  60
61    CTGCTGCGAG  ATGGCAGAAC  ACTAATCGGT  TACCTGAGAA  GCATCGATCA  GTTTGCCAAT  120
121   TTAGTCTTTC  ATCAGACGGT  GGAGCGTATC  CACGTGGGAA  AGAAATTTGG  AGATATTCCC  180
181   AGAGGTATCT  TCATCGTCAG  GGGAGAAAAT  GTAGTCCTGC  TTGGGGAAAT  AGATTTGGAT  240
241   AAGCCCTGCG  ACACAGTCTT  GCAGCAGGTT  TCAATTGAGG  AGATCCTGGA  GGAGCAGCGG  300
301   TTGCAGCAGC  AGGCCAAACA  GGAAACGGAG  AAAGTCAAAA  TGCAAGCTCT  GAAGGACAGA  360
361   GGCCTTTCCA  TACCCAAAGC  TGATAATTTG  GACGAGTATT  GA  402

▼ KEYWORD

ID
Family
Complete proteome
Cytoplasm
mRNA processing
Reference proteome
Ribonucleoprotein
RNA-binding

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Lsm1-7-Pat1 complex
Cellular Component
MRNA cap binding complex
Cellular Component
P-body
Molecular Function
RNA cap binding
Biological Process
Deadenylation-dependent decapping of nuclear-transcribed mRNA
Biological Process
MRNA processing

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Gaa-1715Gasterosteus aculeatus98.51e-79 238
LLPS-Scm-1083Scophthalmus maximus98.52e-79 237
LLPS-Orn-2110Oreochromis niloticus98.51e-79 238
LLPS-Pof-2024Poecilia formosa96.991e-78 235
LLPS-Xim-0643Xiphophorus maculatus95.496e-78 233
LLPS-Ten-3174Tetraodon nigroviridis93.988e-77 231
LLPS-Ict-1483Ictidomys tridecemlineatus92.212e-45 149
LLPS-Tar-2363Takifugu rubripes90.835e-62 194
LLPS-Mam-3349Macaca mulatta89.742e-1776.3
LLPS-Man-3166Macaca nemestrina89.742e-1776.3
LLPS-Scf-2706Scleropages formosus87.975e-70 213
LLPS-Leo-0534Lepisosteus oculatus87.976e-67 206
LLPS-Mup-1062Mustela putorius furo86.471e-69 212
LLPS-Sah-1994Sarcophilus harrisii86.478e-70 213
LLPS-Ora-1014Ornithorhynchus anatinus86.471e-69 213
LLPS-Tag-0051Taeniopygia guttata86.474e-70 214
LLPS-Mod-1732Monodelphis domestica86.478e-70 213
LLPS-Dio-0030Dipodomys ordii85.713e-68 209
LLPS-Tut-1594Tursiops truncatus85.713e-68 209
LLPS-Aim-0875Ailuropoda melanoleuca85.713e-68 209
LLPS-Ova-0040Ovis aries85.713e-68 209
LLPS-Myl-3288Myotis lucifugus85.713e-68 209
LLPS-Paa-1027Papio anubis85.713e-68 209
LLPS-Mal-1107Mandrillus leucophaeus85.713e-68 209
LLPS-Cea-0018Cercocebus atys85.713e-68 209
LLPS-Aon-2361Aotus nancymaae85.713e-68 209
LLPS-Sus-2572Sus scrofa85.711e-68 209
LLPS-Chs-1943Chlorocebus sabaeus85.713e-68 209
LLPS-Maf-1355Macaca fascicularis85.713e-68 209
LLPS-Fud-0635Fukomys damarensis85.713e-68 209
LLPS-Gog-1891Gorilla gorilla85.713e-68 209
LLPS-Cap-0167Cavia porcellus85.713e-68 209
LLPS-Poa-2737Pongo abelii85.713e-68 209
LLPS-Caf-0769Canis familiaris85.713e-68 209
LLPS-Nol-0100Nomascus leucogenys85.713e-68 209
LLPS-Cas-0238Carlito syrichta85.713e-68 209
LLPS-Loa-0012Loxodonta africana85.713e-68 209
LLPS-Fec-1663Felis catus85.713e-68 209
LLPS-Pat-1612Pan troglodytes85.713e-68 209
LLPS-Urm-1462Ursus maritimus85.713e-68 209
LLPS-Pap-1406Pan paniscus85.713e-68 209
LLPS-Hos-0291Homo sapiens85.713e-68 209
LLPS-Rhb-0060Rhinopithecus bieti85.713e-68 209
LLPS-Orc-0306Oryctolagus cuniculus85.713e-68 209
LLPS-Otg-1601Otolemur garnettii85.713e-68 209
LLPS-Bot-1262Bos taurus84.966e-68 208
LLPS-Mum-3199Mus musculus84.963e-67 206
LLPS-Caj-2288Callithrix jacchus84.966e-68 208
LLPS-Asm-1087Astyanax mexicanus84.966e-69 211
LLPS-Fia-1356Ficedula albicollis84.753e-58 182
LLPS-Ran-2587Rattus norvegicus84.211e-67 207
LLPS-Eqc-3245Equus caballus84.212e-67 207
LLPS-Gaga-0302Gallus gallus84.211e-69 212
LLPS-Dar-0293Danio rerio84.213e-69 211
LLPS-Meg-1340Meleagris gallopavo84.214e-69 211
LLPS-Lac-2562Latimeria chalumnae83.95e-56 177
LLPS-Icp-2370Ictalurus punctatus83.462e-68 209
LLPS-Pes-0131Pelodiscus sinensis82.171e-59 187
LLPS-Xet-0133Xenopus tropicalis81.752e-65 201
LLPS-Dos-0670Dothistroma septosporum70.04e-2086.3
LLPS-Spr-1250Sporisorium reilianum68.922e-29 110
LLPS-Usm-0789Ustilago maydis68.922e-29 110
LLPS-Zyt-1376Zymoseptoria tritici67.742e-2086.3
LLPS-Asc-1161Aspergillus clavatus66.671e-26 103
LLPS-Pug-0665Puccinia graminis65.888e-26 100
LLPS-Blg-0023Blumeria graminis65.851e-2499.0
LLPS-Asni-0298Aspergillus niger65.385e-27 103
LLPS-Asfu-1099Aspergillus fumigatus65.383e-27 105
LLPS-Ast-0785Aspergillus terreus65.385e-27 104
LLPS-Nef-0665Neosartorya fischeri65.383e-27 105
LLPS-Ere-0055Erinaceus europaeus63.911e-46 152
LLPS-Mea-4086Mesocricetus auratus63.919e-35 122
LLPS-Cii-1671Ciona intestinalis62.886e-44 147
LLPS-Asf-0439Aspergillus flavus62.824e-2599.8
LLPS-Scp-0048Schizosaccharomyces pombe62.28e-28 105
LLPS-Miv-0151Microbotryum violaceum61.842e-2190.5
LLPS-Mao-0298Magnaporthe oryzae61.432e-1882.0
LLPS-Viv-1237Vitis vinifera61.335e-2392.8
LLPS-Php-0176Physcomitrella patens61.048e-2597.8
LLPS-Chr-0523Chlamydomonas reinhardtii60.492e-2496.3
LLPS-Scc-0072Schizosaccharomyces cryophilus60.267e-26 100
LLPS-Sot-0682Solanum tuberosum60.06e-2392.8
LLPS-Scj-0711Schizosaccharomyces japonicus60.02e-2497.1
LLPS-Cus-0267Cucumis sativus60.01e-2394.4
LLPS-Sol-1874Solanum lycopersicum60.03e-2393.6
LLPS-Cogr-0826Colletotrichum graminicola59.767e-2188.6
LLPS-Drm-0601Drosophila melanogaster59.682e-39 135
LLPS-Sem-0588Selaginella moellendorffii59.527e-2597.8
LLPS-Arl-0904Arabidopsis lyrata58.678e-2392.4
LLPS-Brn-0131Brassica napus58.677e-2392.8
LLPS-Thc-0645Theobroma cacao58.678e-2392.4
LLPS-Bro-0266Brassica oleracea58.677e-2392.8
LLPS-Gor-0366Gossypium raimondii58.674e-2393.2
LLPS-Art-2659Arabidopsis thaliana58.671e-2292.0
LLPS-Nia-1770Nicotiana attenuata58.673e-2291.3
LLPS-Abg-0863Absidia glauca58.564e-33 118
LLPS-Via-1044Vigna angularis57.635e-1777.4
LLPS-Met-0604Medicago truncatula57.333e-2290.9
LLPS-Glm-0137Glycine max57.332e-2291.3
LLPS-Dac-1176Daucus carota57.339e-2392.4
LLPS-Mua-0262Musa acuminata57.331e-2292.0
LLPS-Coc-0647Corchorus capsularis57.334e-2191.7
LLPS-Phv-0404Phaseolus vulgaris57.332e-2291.3
LLPS-Mae-1279Manihot esculenta57.332e-2291.3
LLPS-Trv-1320Trichoderma virens56.981e-2190.1
LLPS-Trr-0377Trichoderma reesei56.671e-2293.2
LLPS-Kop-0784Komagataella pastoris56.583e-2291.7
LLPS-Nec-1084Neurospora crassa56.253e-1881.6
LLPS-Cae-1457Caenorhabditis elegans56.181e-2394.7
LLPS-Fuv-0350Fusarium verticillioides56.11e-1882.4
LLPS-Coo-0716Colletotrichum orbiculare56.14e-1984.0
LLPS-Fuo-0031Fusarium oxysporum56.11e-1882.4
LLPS-Cog-0263Colletotrichum gloeosporioides56.13e-1984.3
LLPS-Hea-1492Helianthus annuus56.04e-2290.5
LLPS-Prp-0821Prunus persica56.06e-2290.1
LLPS-Pot-1543Populus trichocarpa56.07e-2187.4
LLPS-Chc-0229Chondrus crispus55.138e-2497.1
LLPS-Cym-0531Cyanidioschyzon merolae54.932e-1983.6
LLPS-Osl-0053Ostreococcus lucimarinus54.882e-2496.7
LLPS-Mel-0204Melampsora laricipopulina54.815e-2598.6
LLPS-Brr-0563Brassica rapa54.677e-2290.1
LLPS-Amt-0547Amborella trichopoda54.678e-2187.0
LLPS-Hov-1731Hordeum vulgare54.413e-1880.5
LLPS-Gas-0597Galdieria sulphuraria53.856e-2290.9
LLPS-Gag-0579Gaeumannomyces graminis53.665e-1983.6
LLPS-Map-0895Magnaporthe poae53.666e-1983.6
LLPS-Orbr-1069Oryza brachyantha53.525e-1982.8
LLPS-Scs-0047Sclerotinia sclerotiorum53.412e-1984.3
LLPS-Brd-1004Brachypodium distachyon53.332e-2085.9
LLPS-Tra-1117Triticum aestivum53.332e-2085.9
LLPS-Sei-0886Setaria italica53.337e-2187.4
LLPS-Ori-0575Oryza indica53.333e-2085.9
LLPS-Orb-0414Oryza barthii53.333e-2085.9
LLPS-Orm-0978Oryza meridionalis53.331e-2087.4
LLPS-Orr-0078Oryza rufipogon53.333e-2085.9
LLPS-Tru-0931Triticum urartu53.331e-2086.3
LLPS-Zem-1269Zea mays53.331e-2086.7
LLPS-Orp-1768Oryza punctata53.333e-2085.9
LLPS-Ors-1697Oryza sativa53.333e-2085.9
LLPS-Sob-0709Sorghum bicolor53.337e-2187.4
LLPS-Sac-0224Saccharomyces cerevisiae53.251e-2190.5
LLPS-Asg-0665Ashbya gossypii50.579e-2392.8
LLPS-Yal-0828Yarrowia lipolytica49.357e-1674.3
LLPS-Crn-1182Cryptococcus neoformans45.693e-2188.6
LLPS-Beb-0378Beauveria bassiana44.124e-1779.0
LLPS-Fus-0894Fusarium solani43.881e-1882.4
LLPS-Pyt-0274Pyrenophora teres43.336e-1264.3
LLPS-Lem-0188Leptosphaeria maculans42.222e-1162.4
LLPS-Phn-0279Phaeosphaeria nodorum41.112e-1162.4
LLPS-Lep-0325Leersia perrieri36.02e-0853.9
LLPS-Orgl-1858Oryza glumaepatula35.442e-0853.1
LLPS-Orni-1215Oryza nivara35.442e-0853.1
LLPS-Anp-2833Anas platyrhynchos34.182e-0750.1