• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Orc-1002
MRTO4

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Ribosome assembly factor mrt4
Gene Name: MRTO4
Ensembl Gene: ENSOCUG00000000274.3
Ensembl Protein: ENSOCUP00000000241.2
Organism: Oryctolagus cuniculus
Taxa ID: 9986
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Stress granule, OthersPredicted from orthologs(View)

▼ FUNCTION

Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MPKSKRDKKV  SLTKTAKKGL  ELKQNLIEEL  RKCVDTYKYL  FLFSVANMRN  NKLKDIRNAW  60
61    KHSRMFFGKN  KVMMVALGRS  PADEYKDNLH  QVSKKLRGEV  GLLFTDRTKE  EVNEWFTKYA  120
121   EMDYARAGNK  ATFTVSLDPG  PLEQFPHSME  PQLRQLGLPT  ALKRGVVTLL  SDYEVCKEGD  180
181   VLTPEQARVL  KLFGYEMAEF  KVTITYMWDA  QSGRFQQMGD  DLPEGMSESA  TESEEDEND  239
Nucleotide CDS Sequence (FASTA)
1     ATGCCCAAGT  CCAAGCGGGA  CAAGAAAGTG  TCCTTAACCA  AAACTGCCAA  GAAGGGCTTG  60
61    GAGCTGAAGC  AGAACCTGAT  AGAAGAGCTG  CGGAAATGCG  TGGACACGTA  CAAGTACCTG  120
121   TTCCTCTTCT  CCGTGGCCAA  CATGAGGAAC  AACAAGCTGA  AAGACATCCG  GAACGCCTGG  180
181   AAGCACAGCC  GGATGTTCTT  TGGCAAAAAC  AAGGTGATGA  TGGTGGCTTT  GGGCCGGAGC  240
241   CCGGCTGATG  AGTACAAAGA  TAACCTGCAT  CAGGTCAGCA  AGAAGTTGCG  GGGTGAAGTC  300
301   GGCCTCCTTT  TCACAGACCG  CACCAAGGAG  GAGGTGAATG  AGTGGTTCAC  GAAGTATGCG  360
361   GAAATGGACT  ACGCGCGAGC  TGGGAACAAA  GCCACTTTCA  CCGTGAGCCT  GGACCCAGGG  420
421   CCACTGGAGC  AGTTCCCCCA  TTCCATGGAG  CCACAGCTGA  GGCAGCTGGG  CCTGCCCACT  480
481   GCCCTCAAGA  GAGGTGTGGT  GACCCTGCTG  TCTGACTATG  AGGTGTGCAA  GGAGGGCGAC  540
541   GTGCTGACGC  CAGAGCAGGC  CCGGGTCCTG  AAGCTTTTTG  GGTATGAGAT  GGCTGAGTTC  600
601   AAGGTGACCA  TCACATACAT  GTGGGATGCC  CAGTCTGGAA  GGTTCCAACA  GATGGGAGAC  660
661   GACTTGCCAG  AGGGCATGTC  CGAGTCGGCG  ACAGAGTCGG  AGGAAGACGA  GAATGACTGA  720

▼ KEYWORD

ID
Family
Complete proteome
Cytoplasm
Nucleus
Reference proteome
Ribosome biogenesis

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Cellular Component
Nucleolus
Biological Process
Ribosomal large subunit assembly

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Myl-0507Myotis lucifugus96.861e-161 454
LLPS-Otg-1079Otolemur garnettii96.417e-161 452
LLPS-Aon-2594Aotus nancymaae96.416e-161 453
LLPS-Aim-0492Ailuropoda melanoleuca96.416e-161 452
LLPS-Cap-1950Cavia porcellus95.987e-159 447
LLPS-Hos-0180Homo sapiens95.967e-161 452
LLPS-Pat-2815Pan troglodytes95.967e-161 452
LLPS-Ict-1901Ictidomys tridecemlineatus95.968e-161 452
LLPS-Poa-0433Pongo abelii95.967e-161 452
LLPS-Pap-1168Pan paniscus95.527e-160 450
LLPS-Cas-0944Carlito syrichta95.522e-159 449
LLPS-Caf-2962Canis familiaris95.525e-160 450
LLPS-Mup-0508Mustela putorius furo95.529e-159 447
LLPS-Bot-0997Bos taurus95.526e-160 450
LLPS-Eqc-0501Equus caballus95.075e-159 448
LLPS-Mal-0374Mandrillus leucophaeus95.071e-159 449
LLPS-Rhb-1728Rhinopithecus bieti94.621e-158 447
LLPS-Man-1423Macaca nemestrina94.624e-158 446
LLPS-Mam-1070Macaca mulatta94.624e-158 446
LLPS-Maf-1201Macaca fascicularis94.624e-158 446
LLPS-Ran-0392Rattus norvegicus94.325e-123 355
LLPS-Mea-1032Mesocricetus auratus94.221e-158 447
LLPS-Tut-0625Tursiops truncatus94.175e-158 445
LLPS-Fud-0849Fukomys damarensis93.816e-158 445
LLPS-Loa-0769Loxodonta africana93.725e-157 442
LLPS-Mum-0544Mus musculus93.722e-155 438
LLPS-Urm-2623Ursus maritimus93.287e-166 465
LLPS-Chs-1377Chlorocebus sabaeus93.277e-156 440
LLPS-Caj-1348Callithrix jacchus92.893e-166 466
LLPS-Gog-0212Gorilla gorilla92.056e-160 450
LLPS-Fec-0015Felis catus92.023e-163 458
LLPS-Dio-0782Dipodomys ordii90.997e-152 430
LLPS-Ova-0501Ovis aries90.11e-58 187
LLPS-Mod-2992Monodelphis domestica88.247e-148 419
LLPS-Sah-1542Sarcophilus harrisii87.681e-139 398
LLPS-Paa-2571Papio anubis86.042e-142 405
LLPS-Pes-1549Pelodiscus sinensis85.636e-110 322
LLPS-Nol-1209Nomascus leucogenys83.971e-142 406
LLPS-Sus-0155Sus scrofa82.751e-152 433
LLPS-Anp-0054Anas platyrhynchos82.672e-39 137
LLPS-Gaga-3258Gallus gallus81.192e-136 390
LLPS-Lac-0254Latimeria chalumnae80.545e-135 387
LLPS-Meg-0637Meleagris gallopavo80.371e-134 386
LLPS-Tag-0648Taeniopygia guttata79.893e-110 322
LLPS-Fia-0421Ficedula albicollis78.91e-132 381
LLPS-Scf-0003Scleropages formosus78.444e-130 375
LLPS-Xet-0187Xenopus tropicalis78.188e-131 376
LLPS-Scm-0022Scophthalmus maximus77.212e-124 360
LLPS-Ora-0003Ornithorhynchus anatinus76.968e-129 371
LLPS-Leo-1142Lepisosteus oculatus76.712e-125 363
LLPS-Gaa-0982Gasterosteus aculeatus76.712e-123 357
LLPS-Asm-0545Astyanax mexicanus76.421e-120 351
LLPS-Orl-1269Oryzias latipes76.267e-123 356
LLPS-Cea-0480Cercocebus atys76.156e-123 355
LLPS-Pof-0506Poecilia formosa75.85e-122 354
LLPS-Icp-0937Ictalurus punctatus75.661e-127 369
LLPS-Orn-0512Oreochromis niloticus75.575e-124 359
LLPS-Dar-1855Danio rerio74.446e-126 364
LLPS-Tar-2638Takifugu rubripes73.871e-123 358
LLPS-Ten-0227Tetraodon nigroviridis73.218e-123 356
LLPS-Cis-0248Ciona savignyi61.647e-96 289
LLPS-Cii-0010Ciona intestinalis59.644e-68 216
LLPS-Drm-1649Drosophila melanogaster56.058e-83 254
LLPS-Orp-0959Oryza punctata52.05e-2499.0
LLPS-Cae-0776Caenorhabditis elegans50.473e-65 209
LLPS-Mae-1543Manihot esculenta50.01e-67 215
LLPS-Glm-1690Glycine max49.763e-67 214
LLPS-Sei-0193Setaria italica49.532e-65 209
LLPS-Abg-0251Absidia glauca49.31e-65 209
LLPS-Coc-0601Corchorus capsularis49.063e-66 211
LLPS-Dac-0576Daucus carota49.065e-67 213
LLPS-Met-0286Medicago truncatula49.067e-67 213
LLPS-Via-0071Vigna angularis48.876e-36 131
LLPS-Phv-0771Phaseolus vulgaris48.84e-66 211
LLPS-Sob-1042Sorghum bicolor48.581e-64 207
LLPS-Orbr-0617Oryza brachyantha48.589e-66 210
LLPS-Thc-0386Theobroma cacao48.488e-68 215
LLPS-Amt-0057Amborella trichopoda48.331e-64 207
LLPS-Php-0975Physcomitrella patens48.336e-59 192
LLPS-Sol-0257Solanum lycopersicum48.298e-66 210
LLPS-Sot-0334Solanum tuberosum48.293e-65 209
LLPS-Hea-0666Helianthus annuus48.182e-66 211
LLPS-Sem-0939Selaginella moellendorffii48.11e-68 218
LLPS-Brr-2156Brassica rapa47.983e-68 216
LLPS-Bro-1044Brassica oleracea47.982e-68 217
LLPS-Brn-0031Brassica napus47.981e-68 218
LLPS-Lep-0442Leersia perrieri47.623e-62 201
LLPS-Prp-1260Prunus persica47.442e-68 217
LLPS-Chc-0354Chondrus crispus47.47e-50 167
LLPS-Scj-0063Schizosaccharomyces japonicus47.227e-62 201
LLPS-Orb-0356Oryza barthii47.185e-54 181
LLPS-Nia-0816Nicotiana attenuata47.019e-65 207
LLPS-Mua-0575Musa acuminata46.891e-57 189
LLPS-Orm-1543Oryza meridionalis46.83e-55 195
LLPS-Scp-0796Schizosaccharomyces pombe46.761e-61 200
LLPS-Ors-0020Oryza sativa46.74e-61 198
LLPS-Orni-0293Oryza nivara46.74e-61 198
LLPS-Ori-1411Oryza indica46.74e-61 198
LLPS-Pot-2679Populus trichocarpa46.585e-65 208
LLPS-Viv-0130Vitis vinifera46.582e-66 212
LLPS-Gor-0836Gossypium raimondii46.582e-60 196
LLPS-Cus-1934Cucumis sativus46.524e-51 172
LLPS-Usm-0675Ustilago maydis46.083e-62 204
LLPS-Tra-2010Triticum aestivum45.966e-63 203
LLPS-Mel-1010Melampsora laricipopulina45.743e-57 188
LLPS-Zem-0953Zea mays45.653e-60 197
LLPS-Spr-0631Sporisorium reilianum45.623e-62 203
LLPS-Hov-0376Hordeum vulgare45.545e-55 182
LLPS-Art-0182Arabidopsis thaliana45.111e-64 207
LLPS-Miv-0199Microbotryum violaceum44.932e-58 191
LLPS-Brd-0984Brachypodium distachyon44.929e-60 195
LLPS-Yal-0137Yarrowia lipolytica44.392e-57 189
LLPS-Scc-0290Schizosaccharomyces cryophilus44.36e-60 196
LLPS-Org-0068Oryza glaberrima44.251e-58 192
LLPS-Orgl-0268Oryza glumaepatula44.053e-58 192
LLPS-Crn-0159Cryptococcus neoformans43.953e-64 207
LLPS-Dos-0983Dothistroma septosporum43.866e-53 177
LLPS-Nef-0724Neosartorya fischeri43.852e-56 187
LLPS-Asfu-0216Aspergillus fumigatus43.851e-56 187
LLPS-Pug-0300Puccinia graminis43.782e-57 189
LLPS-Tum-1148Tuber melanosporum43.535e-52 175
LLPS-Ast-0779Aspergillus terreus43.352e-53 179
LLPS-Mao-0207Magnaporthe oryzae43.288e-57 188
LLPS-Asni-0217Aspergillus niger43.171e-57 189
LLPS-Chr-0333Chlamydomonas reinhardtii42.81e-58 193
LLPS-Asf-0869Aspergillus flavus42.424e-53 178
LLPS-Aso-0134Aspergillus oryzae42.424e-53 178
LLPS-Asn-0688Aspergillus nidulans42.373e-56 186
LLPS-Blg-0497Blumeria graminis42.178e-60 195
LLPS-Phn-0030Phaeosphaeria nodorum41.994e-58 191
LLPS-Lem-0190Leptosphaeria maculans41.995e-58 190
LLPS-Nec-0262Neurospora crassa41.955e-60 196
LLPS-Put-0407Puccinia triticina41.813e-55 184
LLPS-Map-0508Magnaporthe poae41.632e-59 194
LLPS-Gag-1021Gaeumannomyces graminis41.633e-58 191
LLPS-Pytr-0516Pyrenophora triticirepentis41.562e-58 191
LLPS-Beb-0133Beauveria bassiana41.425e-55 183
LLPS-Fuo-0458Fusarium oxysporum41.22e-53 179
LLPS-Fus-0226Fusarium solani41.15e-52 175
LLPS-Osl-0377Ostreococcus lucimarinus40.762e-49 169
LLPS-Pyt-0156Pyrenophora teres40.699e-57 187
LLPS-Asc-0356Aspergillus clavatus40.595e-53 178
LLPS-Cog-0357Colletotrichum gloeosporioides40.498e-54 180
LLPS-Fuv-0918Fusarium verticillioides40.42e-50 171
LLPS-Zyt-0814Zymoseptoria tritici40.07e-49 167
LLPS-Sac-0060Saccharomyces cerevisiae39.827e-49 167
LLPS-Coo-0320Colletotrichum orbiculare39.762e-56 187
LLPS-Ved-0394Verticillium dahliae39.743e-50 171
LLPS-Cogr-1212Colletotrichum graminicola39.524e-54 181
LLPS-Orr-0618Oryza rufipogon38.428e-38 140
LLPS-Trv-0683Trichoderma virens37.44e-48 165
LLPS-Asg-0767Ashbya gossypii37.231e-47 164
LLPS-Trr-0847Trichoderma reesei36.182e-46 161
LLPS-Gas-0408Galdieria sulphuraria35.685e-45 156
LLPS-Cym-0105Cyanidioschyzon merolae35.622e-42 150
LLPS-Vir-1931Vigna radiata34.92e-28 117
LLPS-Kop-0908Komagataella pastoris34.768e-47 161
LLPS-Tru-2069Triticum urartu31.034e-0753.5
LLPS-Arl-2653Arabidopsis lyrata25.878e-1164.7