• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Caf-2962
MRTO4

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Ribosome assembly factor mrt4
Gene Name: MRTO4
Ensembl Gene: ENSCAFG00000015189.4
Ensembl Protein: ENSCAFP00000040799.1
Organism: Canis familiaris
Taxa ID: 9615
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Stress granule, OthersPredicted from orthologs(View)

▼ FUNCTION

Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MPKSKRDKKV  SLTKTAKKGL  ELKQNLIEEL  RKCVDTYKYL  FIFSVANMRN  SKLKDIRNAW  60
61    KHSRMFFGKN  KVMMVALGRS  PADEYKDNLH  QVSKKLKGEV  GLLFTNRTKE  EVNEWFTKYT  120
121   EMDFARAGNK  ATFTVTLDPG  PLEQFPHSME  PQLRQLGLPT  ALKRGVVTLL  SDHEVCKEGD  180
181   VLTPEQARVL  KLFGYEMAEF  KVTIRYMWDA  QSGRFQQMGE  DLPESASESA  EEESEGEDDG  240
Nucleotide CDS Sequence (FASTA)
1     ATGCCCAAAT  CCAAGCGCGA  CAAGAAAGTT  TCCTTAACCA  AAACTGCCAA  GAAAGGCTTA  60
61    GAACTGAAAC  AGAACCTGAT  AGAAGAGCTT  CGGAAATGTG  TGGACACATA  CAAGTACCTT  120
121   TTCATCTTCT  CCGTGGCCAA  CATGAGGAAC  AGCAAGCTGA  AGGACATCCG  GAACGCCTGG  180
181   AAGCACAGCC  GGATGTTCTT  TGGCAAAAAC  AAGGTGATGA  TGGTGGCCTT  GGGTCGAAGC  240
241   CCAGCTGACG  AGTACAAAGA  CAACCTGCAT  CAGGTCAGCA  AGAAGTTGAA  GGGTGAGGTC  300
301   GGCCTGCTTT  TCACCAACCG  CACCAAGGAG  GAAGTGAATG  AGTGGTTTAC  AAAATACACG  360
361   GAAATGGACT  TCGCTCGAGC  AGGAAACAAA  GCAACTTTCA  CCGTGACCCT  GGACCCAGGG  420
421   CCCCTGGAGC  AGTTCCCCCA  CTCCATGGAG  CCACAGCTGA  GGCAGCTGGG  CCTGCCCACT  480
481   GCCCTCAAGA  GAGGTGTGGT  GACCCTGCTG  TCCGACCACG  AGGTGTGCAA  GGAGGGTGAT  540
541   GTGCTGACCC  CAGAGCAGGC  CCGCGTGCTG  AAGCTTTTCG  GGTATGAGAT  GGCTGAATTC  600
601   AAAGTTACCA  TCAGATACAT  GTGGGATGCA  CAGTCTGGAA  GGTTCCAGCA  GATGGGAGAG  660
661   GACTTGCCCG  AGAGTGCCTC  GGAGTCTGCG  GAGGAAGAAT  CCGAAGGGGA  GGACGATGGC  720
721   TGA  723

▼ KEYWORD

ID
Family
Complete proteome
Cytoplasm
Nucleus
Reference proteome
Ribosome biogenesis

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Cytoplasm
Cellular Component
Nucleolus
Biological Process
Nuclear-transcribed mRNA catabolic process
Biological Process
Ribosomal large subunit assembly
Biological Process
RRNA processing

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Ova-0501Ovis aries98.913e-59 189
LLPS-Aim-0492Ailuropoda melanoleuca98.651e-164 462
LLPS-Urm-2623Ursus maritimus98.653e-164 461
LLPS-Fec-0015Felis catus97.311e-161 454
LLPS-Cap-1950Cavia porcellus96.431e-159 449
LLPS-Ict-1901Ictidomys tridecemlineatus96.413e-161 453
LLPS-Myl-0507Myotis lucifugus95.967e-160 450
LLPS-Mup-0508Mustela putorius furo95.962e-159 449
LLPS-Otg-1079Otolemur garnettii95.962e-160 452
LLPS-Caj-1348Callithrix jacchus95.522e-160 452
LLPS-Bot-0997Bos taurus95.526e-160 450
LLPS-Orc-1002Oryctolagus cuniculus95.525e-160 450
LLPS-Pat-2815Pan troglodytes95.522e-160 451
LLPS-Hos-0180Homo sapiens95.522e-160 451
LLPS-Poa-0433Pongo abelii95.522e-160 451
LLPS-Eqc-0501Equus caballus95.526e-160 450
LLPS-Gog-0212Gorilla gorilla95.072e-159 449
LLPS-Mea-1032Mesocricetus auratus95.072e-158 446
LLPS-Aon-2594Aotus nancymaae95.075e-159 448
LLPS-Mal-0374Mandrillus leucophaeus95.074e-159 448
LLPS-Pap-1168Pan paniscus95.072e-159 449
LLPS-Cas-0944Carlito syrichta95.075e-159 448
LLPS-Fud-0849Fukomys damarensis95.021e-157 444
LLPS-Maf-1201Macaca fascicularis94.621e-157 444
LLPS-Man-1423Macaca nemestrina94.621e-157 444
LLPS-Mam-1070Macaca mulatta94.621e-157 444
LLPS-Ran-0392Rattus norvegicus94.324e-123 355
LLPS-Mum-0544Mus musculus94.179e-156 439
LLPS-Rhb-1728Rhinopithecus bieti94.172e-158 446
LLPS-Chs-1377Chlorocebus sabaeus93.724e-156 441
LLPS-Tut-0625Tursiops truncatus93.273e-157 443
LLPS-Loa-0769Loxodonta africana93.274e-156 441
LLPS-Dio-0782Dipodomys ordii92.791e-153 434
LLPS-Mod-2992Monodelphis domestica88.692e-148 421
LLPS-Sah-1542Sarcophilus harrisii88.632e-140 400
LLPS-Paa-2571Papio anubis86.942e-143 408
LLPS-Nol-1209Nomascus leucogenys85.654e-137 392
LLPS-Pes-1549Pelodiscus sinensis84.482e-108 317
LLPS-Anp-0054Anas platyrhynchos84.01e-39 137
LLPS-Sus-0155Sus scrofa82.683e-151 429
LLPS-Lac-0254Latimeria chalumnae81.93e-136 390
LLPS-Ora-0003Ornithorhynchus anatinus81.62e-129 372
LLPS-Gaga-3258Gallus gallus80.734e-135 387
LLPS-Meg-0637Meleagris gallopavo79.912e-133 383
LLPS-Scf-0003Scleropages formosus79.827e-131 376
LLPS-Cea-0480Cercocebus atys78.929e-118 342
LLPS-Tag-0648Taeniopygia guttata78.82e-110 322
LLPS-Scm-0022Scophthalmus maximus78.68e-126 363
LLPS-Xet-0187Xenopus tropicalis78.189e-131 376
LLPS-Leo-1142Lepisosteus oculatus78.081e-126 366
LLPS-Fia-0421Ficedula albicollis77.981e-131 378
LLPS-Icp-0937Ictalurus punctatus77.738e-128 369
LLPS-Gaa-0982Gasterosteus aculeatus77.632e-124 360
LLPS-Orl-1269Oryzias latipes76.711e-122 355
LLPS-Asm-0545Astyanax mexicanus75.941e-119 348
LLPS-Orn-0512Oreochromis niloticus75.88e-123 356
LLPS-Pof-0506Poecilia formosa75.345e-121 351
LLPS-Tar-2638Takifugu rubripes74.774e-124 359
LLPS-Ten-0227Tetraodon nigroviridis74.114e-123 357
LLPS-Dar-1855Danio rerio73.543e-124 360
LLPS-Cis-0248Ciona savignyi61.193e-95 287
LLPS-Cii-0010Ciona intestinalis60.241e-68 218
LLPS-Drm-1649Drosophila melanogaster56.765e-82 253
LLPS-Orp-0959Oryza punctata52.04e-2499.4
LLPS-Sol-0257Solanum lycopersicum51.675e-65 208
LLPS-Sot-0334Solanum tuberosum51.672e-64 207
LLPS-Cae-0776Caenorhabditis elegans51.44e-66 211
LLPS-Sei-0193Setaria italica50.945e-67 213
LLPS-Mae-1543Manihot esculenta50.942e-67 214
LLPS-Thc-0386Theobroma cacao50.478e-67 213
LLPS-Glm-1690Glycine max50.241e-66 212
LLPS-Nia-0816Nicotiana attenuata50.244e-64 206
LLPS-Viv-0130Vitis vinifera50.246e-66 211
LLPS-Met-0286Medicago truncatula50.09e-67 213
LLPS-Orbr-0617Oryza brachyantha50.02e-67 214
LLPS-Sob-1042Sorghum bicolor50.03e-66 211
LLPS-Php-0975Physcomitrella patens49.763e-60 196
LLPS-Via-0071Vigna angularis49.621e-36 133
LLPS-Prp-1260Prunus persica49.553e-68 216
LLPS-Dac-0576Daucus carota49.531e-66 212
LLPS-Coc-0601Corchorus capsularis49.531e-65 210
LLPS-Amt-0057Amborella trichopoda49.281e-64 207
LLPS-Phv-0771Phaseolus vulgaris49.282e-65 209
LLPS-Tra-2010Triticum aestivum49.062e-64 207
LLPS-Lep-0442Leersia perrieri49.055e-64 206
LLPS-Abg-0251Absidia glauca48.85e-64 205
LLPS-Pot-2679Populus trichocarpa48.654e-65 209
LLPS-Hea-1606Helianthus annuus48.641e-67 214
LLPS-Sem-0939Selaginella moellendorffii48.576e-69 218
LLPS-Brd-0984Brachypodium distachyon48.574e-61 198
LLPS-Chc-0354Chondrus crispus48.521e-49 167
LLPS-Gor-0836Gossypium raimondii48.24e-60 196
LLPS-Scp-0796Schizosaccharomyces pombe48.151e-62 202
LLPS-Orni-0293Oryza nivara48.118e-63 202
LLPS-Ori-1411Oryza indica48.118e-63 202
LLPS-Ors-0020Oryza sativa48.118e-63 202
LLPS-Orb-0356Oryza barthii47.782e-56 187
LLPS-Orm-1543Oryza meridionalis47.572e-54 192
LLPS-Brn-0031Brassica napus47.537e-67 213
LLPS-Brr-2166Brassica rapa47.534e-66 211
LLPS-Bro-1044Brassica oleracea47.532e-66 212
LLPS-Hov-0376Hordeum vulgare47.031e-56 187
LLPS-Zem-0953Zea mays46.966e-62 201
LLPS-Cus-1934Cucumis sativus46.522e-50 170
LLPS-Scj-0063Schizosaccharomyces japonicus46.31e-60 197
LLPS-Art-0182Arabidopsis thaliana46.192e-62 202
LLPS-Usm-0675Ustilago maydis46.081e-60 200
LLPS-Chr-0333Chlamydomonas reinhardtii45.851e-59 196
LLPS-Mua-0575Musa acuminata45.746e-57 187
LLPS-Spr-0631Sporisorium reilianum45.621e-60 199
LLPS-Org-0068Oryza glaberrima45.583e-60 197
LLPS-Orgl-0268Oryza glumaepatula45.376e-60 196
LLPS-Scc-0290Schizosaccharomyces cryophilus45.181e-60 197
LLPS-Miv-0199Microbotryum violaceum45.164e-61 198
LLPS-Crn-0159Cryptococcus neoformans44.891e-62 202
LLPS-Mel-1010Melampsora laricipopulina44.398e-56 185
LLPS-Yal-0137Yarrowia lipolytica43.956e-56 185
LLPS-Pug-0300Puccinia graminis43.788e-58 190
LLPS-Ast-0779Aspergillus terreus43.782e-54 181
LLPS-Lem-0190Leptosphaeria maculans43.295e-60 196
LLPS-Phn-0030Phaeosphaeria nodorum43.293e-60 197
LLPS-Mao-0207Magnaporthe oryzae43.281e-56 187
LLPS-Asni-0217Aspergillus niger43.173e-58 191
LLPS-Dos-0983Dothistroma septosporum43.111e-52 177
LLPS-Tum-1148Tuber melanosporum43.11e-50 171
LLPS-Nef-0724Neosartorya fischeri43.13e-56 186
LLPS-Asfu-0216Aspergillus fumigatus43.13e-56 186
LLPS-Gag-1021Gaeumannomyces graminis42.922e-57 189
LLPS-Asf-0869Aspergillus flavus42.862e-53 179
LLPS-Aso-0134Aspergillus oryzae42.862e-53 179
LLPS-Map-0508Magnaporthe poae42.624e-56 186
LLPS-Pytr-0516Pyrenophora triticirepentis42.429e-60 195
LLPS-Nec-0262Neurospora crassa42.377e-61 198
LLPS-Asn-0688Aspergillus nidulans42.312e-56 187
LLPS-Zyt-0814Zymoseptoria tritici42.222e-52 176
LLPS-Cogr-1212Colletotrichum graminicola42.197e-54 180
LLPS-Coo-0320Colletotrichum orbiculare41.776e-56 186
LLPS-Blg-0497Blumeria graminis41.747e-60 195
LLPS-Pyt-0156Pyrenophora teres41.563e-58 191
LLPS-Osl-0377Ostreococcus lucimarinus41.433e-50 171
LLPS-Cog-0357Colletotrichum gloeosporioides41.352e-53 179
LLPS-Fus-0226Fusarium solani41.17e-52 175
LLPS-Fuo-0458Fusarium oxysporum41.12e-51 174
LLPS-Put-0407Puccinia triticina40.953e-54 181
LLPS-Beb-0133Beauveria bassiana40.591e-53 179
LLPS-Fuv-0918Fusarium verticillioides40.252e-48 166
LLPS-Asc-0356Aspergillus clavatus40.173e-53 178
LLPS-Orr-0618Oryza rufipogon38.926e-38 140
LLPS-Ved-0394Verticillium dahliae38.913e-49 168
LLPS-Sac-0060Saccharomyces cerevisiae38.431e-47 164
LLPS-Trv-0683Trichoderma virens38.146e-47 162
LLPS-Trr-0847Trichoderma reesei36.45e-45 157
LLPS-Gas-0408Galdieria sulphuraria36.153e-45 157
LLPS-Kop-0908Komagataella pastoris36.059e-49 166
LLPS-Asg-0767Ashbya gossypii35.936e-46 159
LLPS-Vir-1931Vigna radiata35.422e-28 117
LLPS-Cym-0105Cyanidioschyzon merolae35.191e-41 148
LLPS-Arl-2653Arabidopsis lyrata25.872e-1166.2