LLPS-Loa-4018
TIMM44
Integrated Annotations
▼ OVERVIEW
| Status: | Unreviewed |
| Protein Name: | Mitochondrial import inner membrane translocase subunit TIM44 |
| Gene Name: | TIMM44 |
| Ensembl Gene: | ENSLAFG00000030514.1 |
| Ensembl Protein: | ENSLAFP00000028832.1 |
| Organism: | Loxodonta africana |
| Taxa ID: | 9785 |
| LLPS Type: | Others |
▼ Classification
Condensates:
| Condensate | Evidence | Orthologs |
|---|---|---|
| Nucleolus, Postsynaptic density | Predicted from orthologs | (View) |
▼ FUNCTION
| Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. |
▼ CROSS REFERENCE
| Database | Nucleotide ID | Protein ID |
|---|---|---|
| Ensembl | ENSLAFT00000032310.1 | ENSLAFP00000028832.1 |
| UniProt | G3ULX3, G3ULX3_LOXAF |
▼ SEQUENCE
| Protein Sequence (FASTA) |
|---|
1 MAAAALRRGW CRCPRRCLGN GVQFLASHNL VPLPYGSTYQ MCRPGRELPL FKSYSSGNRK 60 61 GFLSGLLDNI KQELAKNKEM KESIKKFRDE AKKLEESEAL QEARRKYKTI ESETVRTSEV 120 121 IRKKLGELTG TVKESLDEVS KSDFGRKIKE GVEEAAKTAK QSAESVSKGG EKLGRTAAFK 180 181 AISQGVESVR KEIDESVLGQ TGPYRRPERL RKRTEFAGEK IKEEKVFEPN EEALGVVLHK 240 241 DSKWYQQWKD FKDNNVVFNR FFEMKMKYDE SDNAFIRASR ALTDKVTDLL GGLFSKTEMS 300 301 EVLTEILRVD PAFDKDRFLQ QCQNDIIPNV LEAMIAGELD ILKDWCYEAA RAGLANPGCI 360 361 QWEVLSSWRR PSRAAHLLAP SLQLAMGKMM EQGPVLIITF QAQLVMVIKN PKGEVVEGDP 420 421 DKVLRMLYVW ALCRDQDELN PYAAWRLLDI SASSTEQIL 459 |
| Nucleotide CDS Sequence (FASTA) |
1 ATGGCGGCGG CGGCGCTGCG GCGAGGCTGG TGCCGCTGCC CGCGGAGATG CCTCGGGAAT 60 61 GGAGTCCAGT TTCTTGCCAG CCACAACCTA GTCCCTCTGC CCTACGGTTC GACTTATCAG 120 121 ATGTGCCGAC CAGGTAGAGA GCTGCCCCTG TTCAAATCCT ATTCTTCTGG CAACAGAAAA 180 181 GGCTTCCTGT CCGGCTTGCT AGATAATATC AAACAGGAGT TAGCCAAAAA CAAAGAAATG 240 241 AAAGAAAGTA TAAAAAAATT CCGAGACGAG GCCAAGAAGC TGGAAGAATC GGAAGCGCTC 300 301 CAGGAAGCCC GAAGGAAATA CAAAACCATC GAATCCGAGA CCGTCAGGAC CAGTGAAGTG 360 361 ATCAGGAAGA AGCTCGGGGA ACTCACAGGC ACAGTGAAGG AGAGTCTTGA TGAAGTCAGT 420 421 AAAAGTGACT TTGGCCGGAA AATCAAGGAG GGTGTGGAAG AAGCAGCCAA GACGGCCAAG 480 481 CAGTCGGCTG AGTCAGTGTC CAAGGGTGGG GAGAAGCTGG GCAGGACTGC GGCCTTCAAA 540 541 GCCATATCCC AGGGTGTGGA GTCTGTGAGG AAGGAGATTG ACGAGAGTGT CCTGGGCCAG 600 601 ACAGGGCCCT ACCGGAGGCC GGAGCGGCTC AGGAAGAGGA CAGAATTCGC AGGAGAGAAA 660 661 ATCAAGGAAG AGAAAGTGTT TGAGCCCAAT GAGGAGGCCC TGGGCGTCGT GCTCCACAAG 720 721 GACTCCAAGT GGTACCAGCA GTGGAAGGAC TTCAAGGACA ACAACGTGGT CTTTAATCGC 780 781 TTCTTTGAGA TGAAGATGAA GTACGACGAG AGCGACAATG CGTTCATCCG CGCGTCCCGG 840 841 GCACTCACTG ACAAGGTCAC AGACCTGCTG GGGGGCCTCT TCTCGAAGAC AGAGATGTCA 900 901 GAGGTGCTAA CGGAGATCCT GCGGGTGGAC CCCGCCTTCG ACAAGGACCG CTTCCTGCAG 960 961 CAGTGCCAGA ATGACATCAT TCCCAACGTC CTGGAGGCCA TGATTGCTGG AGAGCTTGAC 1020 1021 ATTCTCAAAG ACTGGTGCTA TGAAGCCGCT AGGGCTGGGC TTGCCAATCC TGGTTGCATC 1080 1081 CAGTGGGAGG TACTGAGCTC CTGGAGGAGG CCCAGCCGGG CTGCTCACCT GTTGGCCCCT 1140 1141 TCCCTGCAGC TGGCCATGGG CAAGATGATG GAGCAGGGGC CTGTGCTGAT CATCACCTTC 1200 1201 CAGGCCCAGC TGGTGATGGT GATCAAGAAC CCCAAGGGGG AGGTGGTCGA GGGTGACCCG 1260 1261 GATAAAGTAC TGCGCATGCT ATACGTATGG GCGCTTTGCC GGGACCAGGA CGAGCTGAAC 1320 1321 CCCTACGCTG CCTGGCGGCT CCTGGACATC TCTGCCTCCA GCACAGAGCA GATCCTCTGA 1380 |
▼ KEYWORD
▼ GENE ONTOLOGY
ID | Classification | Description |
Cellular Component | Mitochondrial inner membrane | |
Cellular Component | Mitochondrial matrix | |
Molecular Function | Chaperone binding | |
Biological Process | Protein import into mitochondrial matrix |
▼ ORTHOLOGY
| DrLLPS ID | Organism | Identity | E-value | Score |
|---|---|---|---|---|
| LLPS-Chs-1586 | Chlorocebus sabaeus | 87.59 | 0.0 | 736 |
| LLPS-Eqc-2296 | Equus caballus | 87.34 | 0.0 | 805 |
| LLPS-Hos-0354 | Homo sapiens | 87.15 | 0.0 | 811 |
| LLPS-Bot-0568 | Bos taurus | 87.09 | 0.0 | 802 |
| LLPS-Caf-0392 | Canis familiaris | 86.93 | 0.0 | 803 |
| LLPS-Gog-2011 | Gorilla gorilla | 86.93 | 0.0 | 810 |
| LLPS-Dio-0549 | Dipodomys ordii | 86.81 | 0.0 | 792 |
| LLPS-Pat-1761 | Pan troglodytes | 86.71 | 0.0 | 806 |
| LLPS-Ict-0311 | Ictidomys tridecemlineatus | 86.71 | 0.0 | 808 |
| LLPS-Paa-0069 | Papio anubis | 86.68 | 0.0 | 803 |
| LLPS-Urm-1536 | Ursus maritimus | 86.49 | 0.0 | 795 |
| LLPS-Rhb-3421 | Rhinopithecus bieti | 86.46 | 0.0 | 802 |
| LLPS-Mal-1986 | Mandrillus leucophaeus | 86.46 | 0.0 | 800 |
| LLPS-Orc-1538 | Oryctolagus cuniculus | 86.27 | 0.0 | 803 |
| LLPS-Pap-1768 | Pan paniscus | 86.27 | 0.0 | 803 |
| LLPS-Mam-0295 | Macaca mulatta | 86.24 | 0.0 | 800 |
| LLPS-Otg-2534 | Otolemur garnettii | 86.06 | 0.0 | 792 |
| LLPS-Fec-4175 | Felis catus | 86.06 | 0.0 | 798 |
| LLPS-Fud-3056 | Fukomys damarensis | 86.06 | 0.0 | 771 |
| LLPS-Mea-1663 | Mesocricetus auratus | 86.06 | 0.0 | 790 |
| LLPS-Sus-1093 | Sus scrofa | 86.06 | 0.0 | 792 |
| LLPS-Maf-3893 | Macaca fascicularis | 86.04 | 0.0 | 768 |
| LLPS-Poa-1257 | Pongo abelii | 85.84 | 0.0 | 792 |
| LLPS-Cas-0628 | Carlito syrichta | 85.62 | 0.0 | 790 |
| LLPS-Myl-1950 | Myotis lucifugus | 85.62 | 0.0 | 788 |
| LLPS-Aon-4204 | Aotus nancymaae | 85.4 | 0.0 | 798 |
| LLPS-Man-0705 | Macaca nemestrina | 85.2 | 0.0 | 721 |
| LLPS-Mup-1764 | Mustela putorius furo | 85.19 | 0.0 | 787 |
| LLPS-Ran-2328 | Rattus norvegicus | 85.0 | 0.0 | 782 |
| LLPS-Cea-2819 | Cercocebus atys | 84.78 | 0.0 | 773 |
| LLPS-Cap-2488 | Cavia porcellus | 84.75 | 0.0 | 784 |
| LLPS-Mum-3720 | Mus musculus | 84.53 | 0.0 | 788 |
| LLPS-Caj-1372 | Callithrix jacchus | 84.1 | 0.0 | 784 |
| LLPS-Ova-0027 | Ovis aries | 83.81 | 0.0 | 744 |
| LLPS-Nol-0199 | Nomascus leucogenys | 81.28 | 0.0 | 756 |
| LLPS-Sah-0267 | Sarcophilus harrisii | 81.18 | 0.0 | 755 |
| LLPS-Tag-3148 | Taeniopygia guttata | 79.36 | 0.0 | 563 |
| LLPS-Pes-1340 | Pelodiscus sinensis | 79.16 | 0.0 | 714 |
| LLPS-Anp-0285 | Anas platyrhynchos | 79.02 | 0.0 | 719 |
| LLPS-Mod-1061 | Monodelphis domestica | 78.95 | 0.0 | 667 |
| LLPS-Meg-1479 | Meleagris gallopavo | 78.7 | 0.0 | 711 |
| LLPS-Gaga-3086 | Gallus gallus | 77.83 | 0.0 | 714 |
| LLPS-Fia-2540 | Ficedula albicollis | 75.49 | 0.0 | 699 |
| LLPS-Scf-2891 | Scleropages formosus | 75.44 | 0.0 | 609 |
| LLPS-Xet-1207 | Xenopus tropicalis | 73.82 | 0.0 | 641 |
| LLPS-Ora-2730 | Ornithorhynchus anatinus | 73.42 | 0.0 | 660 |
| LLPS-Asm-1331 | Astyanax mexicanus | 72.75 | 0.0 | 596 |
| LLPS-Tar-1649 | Takifugu rubripes | 72.14 | 0.0 | 605 |
| LLPS-Dar-1101 | Danio rerio | 70.2 | 0.0 | 630 |
| LLPS-Xim-1203 | Xiphophorus maculatus | 69.93 | 0.0 | 618 |
| LLPS-Lac-0444 | Latimeria chalumnae | 69.81 | 0.0 | 560 |
| LLPS-Ten-2508 | Tetraodon nigroviridis | 69.41 | 0.0 | 627 |
| LLPS-Pof-1320 | Poecilia formosa | 69.3 | 0.0 | 609 |
| LLPS-Scm-2163 | Scophthalmus maximus | 68.33 | 0.0 | 608 |
| LLPS-Orl-3122 | Oryzias latipes | 68.13 | 0.0 | 609 |
| LLPS-Orn-2845 | Oreochromis niloticus | 67.46 | 0.0 | 601 |
| LLPS-Icp-3349 | Ictalurus punctatus | 67.38 | 0.0 | 610 |
| LLPS-Gaa-2403 | Gasterosteus aculeatus | 67.18 | 0.0 | 603 |
| LLPS-Leo-0701 | Lepisosteus oculatus | 63.02 | 0.0 | 540 |
| LLPS-Drm-2035 | Drosophila melanogaster | 48.18 | 3e-135 | 405 |
| LLPS-Cae-1940 | Caenorhabditis elegans | 41.52 | 1e-108 | 335 |
| LLPS-Cym-0201 | Cyanidioschyzon merolae | 40.38 | 5e-08 | 55.8 |
| LLPS-Cii-2053 | Ciona intestinalis | 39.95 | 2e-95 | 301 |
| LLPS-Cis-0086 | Ciona savignyi | 37.8 | 5e-96 | 303 |
| LLPS-Gas-0054 | Galdieria sulphuraria | 32.02 | 1e-20 | 96.7 |
| LLPS-Pytr-0305 | Pyrenophora triticirepentis | 32.0 | 2e-29 | 123 |
| LLPS-Pyt-1015 | Pyrenophora teres | 32.0 | 1e-28 | 122 |
| LLPS-Phn-0429 | Phaeosphaeria nodorum | 31.65 | 5e-23 | 104 |
| LLPS-Fuv-0620 | Fusarium verticillioides | 31.06 | 9e-27 | 115 |
| LLPS-Abg-0956 | Absidia glauca | 30.12 | 2e-51 | 192 |
| LLPS-Chc-0659 | Chondrus crispus | 29.94 | 2e-15 | 82.0 |
| LLPS-Asc-0751 | Aspergillus clavatus | 29.92 | 4e-29 | 123 |
| LLPS-Trv-0579 | Trichoderma virens | 28.89 | 4e-36 | 142 |
| LLPS-Ved-1253 | Verticillium dahliae | 28.75 | 8e-34 | 137 |
| LLPS-Pug-0667 | Puccinia graminis | 28.67 | 7e-07 | 55.8 |
| LLPS-Put-0631 | Puccinia triticina | 28.67 | 8e-07 | 55.5 |
| LLPS-Tru-0662 | Triticum urartu | 28.57 | 1e-12 | 73.6 |
| LLPS-Cogr-1385 | Colletotrichum graminicola | 28.22 | 3e-31 | 129 |
| LLPS-Tra-0155 | Triticum aestivum | 28.18 | 1e-12 | 73.9 |
| LLPS-Hov-0570 | Hordeum vulgare | 28.18 | 2e-12 | 73.2 |
| LLPS-Tum-0765 | Tuber melanosporum | 27.98 | 5e-35 | 140 |
| LLPS-Ast-0875 | Aspergillus terreus | 27.95 | 1e-34 | 139 |
| LLPS-Beb-0760 | Beauveria bassiana | 27.9 | 9e-32 | 130 |
| LLPS-Nec-1412 | Neurospora crassa | 27.82 | 4e-35 | 141 |
| LLPS-Chr-1042 | Chlamydomonas reinhardtii | 27.78 | 3e-09 | 62.8 |
| LLPS-Cog-0476 | Colletotrichum gloeosporioides | 27.76 | 9e-28 | 119 |
| LLPS-Coo-0590 | Colletotrichum orbiculare | 27.76 | 4e-29 | 122 |
| LLPS-Trr-0741 | Trichoderma reesei | 27.59 | 1e-35 | 142 |
| LLPS-Gag-1440 | Gaeumannomyces graminis | 27.43 | 2e-31 | 130 |
| LLPS-Fus-0410 | Fusarium solani | 27.38 | 9e-32 | 130 |
| LLPS-Yal-0060 | Yarrowia lipolytica | 27.38 | 1e-25 | 112 |
| LLPS-Asni-0924 | Aspergillus niger | 27.05 | 2e-35 | 142 |
| LLPS-Zyt-0104 | Zymoseptoria tritici | 27.01 | 5e-28 | 119 |
| LLPS-Map-0639 | Magnaporthe poae | 26.94 | 1e-30 | 127 |
| LLPS-Mao-1424 | Magnaporthe oryzae | 26.78 | 3e-31 | 129 |
| LLPS-Fuo-0337 | Fusarium oxysporum | 26.41 | 3e-32 | 132 |
| LLPS-Scp-0358 | Schizosaccharomyces pombe | 26.3 | 2e-35 | 140 |
| LLPS-Scc-0271 | Schizosaccharomyces cryophilus | 26.15 | 2e-32 | 132 |
| LLPS-Asn-0065 | Aspergillus nidulans | 26.09 | 4e-32 | 132 |
| LLPS-Asf-0317 | Aspergillus flavus | 26.02 | 5e-30 | 125 |
| LLPS-Aso-0419 | Aspergillus oryzae | 26.02 | 2e-30 | 127 |
| LLPS-Osl-0832 | Ostreococcus lucimarinus | 25.99 | 7e-10 | 63.9 |
| LLPS-Lem-1605 | Leptosphaeria maculans | 25.92 | 2e-28 | 121 |
| LLPS-Bro-0799 | Brassica oleracea | 25.87 | 5e-12 | 71.6 |
| LLPS-Sem-2146 | Selaginella moellendorffii | 25.75 | 2e-17 | 88.6 |
| LLPS-Sac-1395 | Saccharomyces cerevisiae | 25.73 | 2e-26 | 114 |
| LLPS-Usm-0154 | Ustilago maydis | 25.66 | 7e-18 | 90.5 |
| LLPS-Nef-1474 | Neosartorya fischeri | 25.55 | 6e-29 | 122 |
| LLPS-Crn-0477 | Cryptococcus neoformans | 25.45 | 2e-22 | 103 |
| LLPS-Blg-0269 | Blumeria graminis | 25.42 | 2e-26 | 115 |
| LLPS-Sot-0605 | Solanum tuberosum | 25.41 | 5e-09 | 60.1 |
| LLPS-Kop-0675 | Komagataella pastoris | 25.37 | 3e-26 | 113 |
| LLPS-Dos-0156 | Dothistroma septosporum | 25.06 | 2e-27 | 119 |
| LLPS-Scj-0970 | Schizosaccharomyces japonicus | 25.0 | 6e-26 | 112 |
| LLPS-Gor-2501 | Gossypium raimondii | 24.59 | 1e-14 | 80.5 |
| LLPS-Sol-1641 | Solanum lycopersicum | 24.44 | 2e-12 | 73.2 |
| LLPS-Asfu-0204 | Aspergillus fumigatus | 24.4 | 2e-26 | 115 |
| LLPS-Spr-1449 | Sporisorium reilianum | 24.37 | 9e-18 | 89.7 |
| LLPS-Asg-0003 | Ashbya gossypii | 24.25 | 4e-22 | 102 |
| LLPS-Viv-1757 | Vitis vinifera | 24.15 | 2e-18 | 92.0 |
| LLPS-Vir-0958 | Vigna radiata | 24.0 | 1e-09 | 64.7 |
| LLPS-Via-0877 | Vigna angularis | 23.92 | 2e-13 | 76.3 |
| LLPS-Dac-0144 | Daucus carota | 23.89 | 9e-14 | 77.4 |
| LLPS-Mel-0112 | Melampsora laricipopulina | 23.67 | 8e-21 | 99.0 |
| LLPS-Brn-1840 | Brassica napus | 23.66 | 2e-15 | 82.4 |
| LLPS-Art-0307 | Arabidopsis thaliana | 23.63 | 2e-13 | 76.3 |
| LLPS-Pot-0875 | Populus trichocarpa | 23.55 | 1e-17 | 89.4 |
| LLPS-Brr-0914 | Brassica rapa | 23.44 | 8e-15 | 80.5 |
| LLPS-Mae-0173 | Manihot esculenta | 23.37 | 2e-18 | 91.7 |
| LLPS-Miv-0485 | Microbotryum violaceum | 23.26 | 1e-19 | 95.5 |
| LLPS-Arl-1260 | Arabidopsis lyrata | 23.21 | 4e-14 | 78.2 |
| LLPS-Hea-1068 | Helianthus annuus | 23.11 | 6e-11 | 68.2 |
| LLPS-Phv-1552 | Phaseolus vulgaris | 22.59 | 4e-12 | 72.0 |
| LLPS-Thc-0860 | Theobroma cacao | 22.59 | 1e-15 | 83.6 |
| LLPS-Met-0324 | Medicago truncatula | 22.11 | 5e-15 | 80.9 |
| LLPS-Glm-0999 | Glycine max | 21.84 | 4e-14 | 78.6 |
| LLPS-Amt-0255 | Amborella trichopoda | 21.62 | 9e-12 | 70.9 |
| LLPS-Php-0171 | Physcomitrella patens | 21.43 | 1e-11 | 70.1 |