• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Caj-1372
TIMM44

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Mitochondrial import inner membrane translocase subunit TIM44
Gene Name: TIMM44
Ensembl Gene: ENSCJAG00000006140.3
Ensembl Protein: ENSCJAP00000011309.2
Organism: Callithrix jacchus
Taxa ID: 9483
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Postsynaptic densityPredicted from orthologs(View)

▼ FUNCTION

Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MAAAALRSGW  CRCPRRCLSG  GIHFFSSHSL  PHGLTYQMRR  PGRELPLSKS  YSSGNRKGFL  60
61    SGLLDNIKQE  LAKNEEMKES  IKKFRDEARR  LEESDTLQEA  RRKYKTMESE  TMRTSEVLWK  120
121   KLGELTGTMK  ESLHEVSKSD  LGRKIKEGVE  EVAKTAKQSA  ESMSKGGEKL  GRTAAFRALS  180
181   QGVESVKKEI  DDSVLGQTGP  YRRPQRLRKR  TEFAGEKFKE  EKVFEPNEEA  LGVVLHKDSR  240
241   WYQQWKDFKE  NNVVFNRFFE  MKVKYDESDN  ALIRASRALT  DKVTDLLGGL  FSKTEMSEAL  300
301   TEILRVDPAF  DKDRFLKQCE  NDIIPNVLEA  MISGELDILK  DWCYEATYSQ  LAHPIQQAKA  360
361   LGLQFHSRIL  DIDNVDLAMG  KMMEQGPVLI  ITFQAQLVML  VRNPKGEVVE  GDPDKVLRML  420
421   YVWALCRDQD  ELNPYAAWRL  LDISASSTEQ  IL  452
Nucleotide CDS Sequence (FASTA)
1     ATGGCGGCGG  CGGCGCTACG  GAGTGGCTGG  TGCCGCTGTC  CGCGGAGATG  CCTCAGCGGT  60
61    GGAATCCACT  TTTTTTCCAG  CCACAGCCTA  CCCCATGGGT  TGACCTATCA  GATGCGCCGG  120
121   CCGGGCAGAG  AGCTGCCACT  GTCCAAATCA  TATTCTTCTG  GAAACAGAAA  AGGCTTTCTG  180
181   TCCGGCTTGC  TAGATAATAT  CAAACAAGAA  TTAGCCAAAA  ACGAAGAAAT  GAAAGAAAGT  240
241   ATTAAAAAAT  TTCGCGATGA  GGCCAGGAGG  CTGGAAGAAT  CAGACACGCT  CCAGGAGGCC  300
301   AGAAGGAAAT  ACAAAACCAT  GGAGTCAGAA  ACCATGCGGA  CAAGTGAGGT  GCTATGGAAG  360
361   AAGCTTGGGG  AGCTGACAGG  CACCATGAAG  GAGAGCCTTC  ATGAAGTGAG  TAAAAGTGAT  420
421   CTTGGCCGGA  AAATCAAGGA  GGGTGTGGAG  GAAGTGGCCA  AGACGGCCAA  GCAGTCAGCC  480
481   GAGTCGATGT  CCAAAGGCGG  GGAGAAGCTG  GGTAGGACAG  CGGCCTTCAG  AGCCCTCTCC  540
541   CAGGGGGTGG  AGTCCGTGAA  GAAGGAAATT  GACGACAGTG  TCCTGGGGCA  GACAGGGCCC  600
601   TACCGAAGGC  CCCAGCGACT  CCGAAAGAGG  ACAGAGTTTG  CAGGAGAGAA  GTTCAAGGAG  660
661   GAGAAAGTGT  TTGAACCAAA  CGAGGAGGCC  CTGGGAGTCG  TTCTGCATAA  GGACTCCAGG  720
721   TGGTACCAGC  AGTGGAAGGA  TTTCAAGGAG  AACAACGTGG  TGTTCAACCG  GTTCTTCGAG  780
781   ATGAAGGTGA  AGTATGACGA  AAGCGACAAT  GCGCTCATTC  GGGCGTCCCG  GGCCCTGACG  840
841   GACAAGGTCA  CCGACCTGCT  CGGGGGCCTG  TTCTCGAAGA  CAGAGATGTC  AGAGGCACTC  900
901   ACGGAGATCC  TCCGGGTGGA  CCCGGCCTTC  GACAAGGACC  GGTTTCTAAA  GCAGTGTGAG  960
961   AATGACATCA  TCCCCAACGT  CCTGGAGGCT  ATGATTTCTG  GAGAGCTTGA  CATTCTCAAA  1020
1021  GACTGGTGCT  ATGAAGCTAC  TTATAGCCAG  TTGGCCCACC  CCATCCAGCA  GGCCAAGGCG  1080
1081  CTGGGCCTCC  AGTTCCATTC  TCGCATCCTA  GACATCGACA  ACGTTGATCT  GGCCATGGGC  1140
1141  AAGATGATGG  AGCAAGGGCC  AGTGCTGATC  ATCACCTTCC  AAGCGCAGCT  GGTGATGCTG  1200
1201  GTCAGGAACC  CCAAAGGCGA  GGTGGTGGAA  GGTGACCCGG  ACAAGGTGCT  GCGGATGCTG  1260
1261  TACGTGTGGG  CACTCTGCCG  AGACCAGGAT  GAGCTCAACC  CCTATGCAGC  CTGGCGGCTC  1320
1321  CTGGACATCT  CAGCCTCCAG  CACAGAGCAG  ATCCTCTGA  1359

▼ KEYWORD

ID
Family
Coiled coil
Complete proteome
Membrane
Mitochondrion
Mitochondrion inner membrane
Protein transport
Reference proteome
Translocation
Transport

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Mitochondrial inner membrane
Cellular Component
Mitochondrial matrix
Molecular Function
Chaperone binding
Biological Process
Protein import into mitochondrial matrix

▼ KEGG


▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Aon-4204Aotus nancymaae97.570.0 909
LLPS-Chs-1586Chlorocebus sabaeus95.90.0 817
LLPS-Hos-0354Homo sapiens95.130.0 893
LLPS-Gog-2011Gorilla gorilla94.910.0 890
LLPS-Pat-1761Pan troglodytes94.690.0 887
LLPS-Paa-0069Papio anubis94.680.0 884
LLPS-Mal-1986Mandrillus leucophaeus94.460.0 881
LLPS-Pap-1768Pan paniscus94.250.0 884
LLPS-Rhb-3421Rhinopithecus bieti94.240.0 880
LLPS-Mam-0295Macaca mulatta94.240.0 881
LLPS-Poa-1257Pongo abelii94.030.0 876
LLPS-Man-0705Macaca nemestrina93.930.0 800
LLPS-Maf-3893Macaca fascicularis92.840.0 847
LLPS-Cea-2819Cercocebus atys92.260.0 851
LLPS-Otg-2534Otolemur garnettii90.490.0 847
LLPS-Dio-0549Dipodomys ordii90.380.0 851
LLPS-Nol-0199Nomascus leucogenys90.130.0 828
LLPS-Orc-1538Oryctolagus cuniculus89.820.0 853
LLPS-Ict-0311Ictidomys tridecemlineatus89.820.0 855
LLPS-Caf-0392Canis familiaris89.670.0 845
LLPS-Mup-1764Mustela putorius furo89.650.0 840
LLPS-Fec-4175Felis catus89.430.0 850
LLPS-Eqc-2296Equus caballus89.210.0 839
LLPS-Urm-1536Ursus maritimus89.010.0 837
LLPS-Cas-0628Carlito syrichta88.940.0 837
LLPS-Sus-1093Sus scrofa88.790.0 835
LLPS-Fud-3056Fukomys damarensis88.50.0 819
LLPS-Cap-2488Cavia porcellus88.50.0 837
LLPS-Bot-0568Bos taurus88.30.0 835
LLPS-Mea-1663Mesocricetus auratus87.170.0 833
LLPS-Ran-2328Rattus norvegicus86.980.0 823
LLPS-Myl-1950Myotis lucifugus86.810.0 815
LLPS-Mum-3720Mus musculus86.730.0 828
LLPS-Ova-0027Ovis aries85.210.0 773
LLPS-Loa-4018Loxodonta africana84.10.0 784
LLPS-Pes-1340Pelodiscus sinensis81.210.0 754
LLPS-Sah-0267Sarcophilus harrisii81.020.0 773
LLPS-Anp-0285Anas platyrhynchos80.180.0 752
LLPS-Meg-1479Meleagris gallopavo79.910.0 751
LLPS-Gaga-3086Gallus gallus79.390.0 754
LLPS-Scf-2891Scleropages formosus79.280.0 661
LLPS-Mod-1061Monodelphis domestica79.230.0 690
LLPS-Fia-2540Ficedula albicollis77.460.0 740
LLPS-Tag-3148Taeniopygia guttata76.90.0 594
LLPS-Asm-1331Astyanax mexicanus76.660.0 649
LLPS-Xet-1207Xenopus tropicalis75.410.0 679
LLPS-Ora-2730Ornithorhynchus anatinus74.510.0 688
LLPS-Tar-1649Takifugu rubripes73.930.0 650
LLPS-Pof-1320Poecilia formosa73.450.0 661
LLPS-Xim-1203Xiphophorus maculatus73.250.0 668
LLPS-Dar-1101Danio rerio73.190.0 676
LLPS-Lac-0444Latimeria chalumnae73.170.0 610
LLPS-Ten-2508Tetraodon nigroviridis72.810.0 679
LLPS-Scm-3257Scophthalmus maximus72.280.0 620
LLPS-Gaa-2403Gasterosteus aculeatus71.180.0 661
LLPS-Icp-3349Ictalurus punctatus70.810.0 662
LLPS-Orn-2845Oreochromis niloticus70.580.0 645
LLPS-Orl-3122Oryzias latipes70.420.0 654
LLPS-Leo-0701Lepisosteus oculatus64.350.0 582
LLPS-Drm-2035Drosophila melanogaster51.363e-150 442
LLPS-Cym-0201Cyanidioschyzon merolae46.557e-1267.0
LLPS-Cii-2053Ciona intestinalis41.953e-107 332
LLPS-Cae-1940Caenorhabditis elegans41.946e-114 348
LLPS-Cis-0086Ciona savignyi39.817e-103 320
LLPS-Gas-0054Galdieria sulphuraria36.536e-30 123
LLPS-Phn-0429Phaeosphaeria nodorum35.277e-32 130
LLPS-Fuv-0620Fusarium verticillioides34.252e-34 137
LLPS-Chc-0659Chondrus crispus33.743e-25 110
LLPS-Pyt-1015Pyrenophora teres31.382e-38 150
LLPS-Pytr-0305Pyrenophora triticirepentis31.381e-38 151
LLPS-Cog-0476Colletotrichum gloeosporioides31.093e-38 150
LLPS-Abg-0956Absidia glauca30.79e-57 207
LLPS-Nia-1272Nicotiana attenuata30.615e-0858.5
LLPS-Ast-0875Aspergillus terreus30.589e-45 168
LLPS-Osl-0832Ostreococcus lucimarinus30.542e-1683.2
LLPS-Chr-1042Chlamydomonas reinhardtii30.292e-1479.0
LLPS-Ved-1253Verticillium dahliae30.181e-42 162
LLPS-Asni-0924Aspergillus niger30.082e-44 167
LLPS-Lem-1605Leptosphaeria maculans30.083e-38 150
LLPS-Trv-0579Trichoderma virens30.083e-43 161
LLPS-Tum-0765Tuber melanosporum30.051e-44 168
LLPS-Cogr-1385Colletotrichum graminicola29.99e-40 154
LLPS-Fus-0410Fusarium solani29.758e-40 154
LLPS-Gag-1440Gaeumannomyces graminis29.551e-40 157
LLPS-Coo-0590Colletotrichum orbiculare29.494e-38 149
LLPS-Bro-0799Brassica oleracea29.472e-1891.7
LLPS-Yal-0060Yarrowia lipolytica29.312e-36 144
LLPS-Trr-0741Trichoderma reesei29.232e-42 162
LLPS-Orni-0498Oryza nivara29.12e-1891.3
LLPS-Ori-0134Oryza indica29.12e-1891.7
LLPS-Orb-0143Oryza barthii29.12e-1891.7
LLPS-Orgl-0663Oryza glumaepatula29.12e-1892.0
LLPS-Orp-1157Oryza punctata29.19e-1992.8
LLPS-Ors-1545Oryza sativa29.12e-1891.7
LLPS-Org-0198Oryza glaberrima29.12e-1891.3
LLPS-Orr-0333Oryza rufipogon29.12e-1891.7
LLPS-Map-0639Magnaporthe poae29.041e-39 154
LLPS-Nec-1412Neurospora crassa28.931e-41 160
LLPS-Beb-0760Beauveria bassiana28.791e-39 154
LLPS-Pug-0667Puccinia graminis28.774e-1375.5
LLPS-Put-0631Puccinia triticina28.775e-1375.1
LLPS-Fuo-0337Fusarium oxysporum28.754e-39 152
LLPS-Nef-1474Neosartorya fischeri28.683e-38 150
LLPS-Usm-0154Ustilago maydis28.387e-27 117
LLPS-Asc-0751Aspergillus clavatus28.321e-38 151
LLPS-Mao-1424Magnaporthe oryzae28.115e-39 152
LLPS-Zyt-0104Zymoseptoria tritici28.118e-37 145
LLPS-Sob-1914Sorghum bicolor28.041e-1789.4
LLPS-Asfu-0204Aspergillus fumigatus27.946e-37 146
LLPS-Kop-0675Komagataella pastoris27.931e-34 138
LLPS-Asn-0065Aspergillus nidulans27.822e-40 156
LLPS-Sei-0375Setaria italica27.784e-1890.9
LLPS-Orbr-0152Oryza brachyantha27.541e-1892.0
LLPS-Tra-0155Triticum aestivum27.511e-1789.0
LLPS-Hov-0570Hordeum vulgare27.513e-1788.2
LLPS-Tru-0662Triticum urartu27.511e-1789.4
LLPS-Amt-0255Amborella trichopoda27.482e-1788.6
LLPS-Brd-1698Brachypodium distachyon27.422e-1788.6
LLPS-Sac-1395Saccharomyces cerevisiae27.327e-33 133
LLPS-Blg-0269Blumeria graminis27.35e-33 134
LLPS-Scp-0358Schizosaccharomyces pombe27.236e-44 165
LLPS-Asg-0003Ashbya gossypii27.081e-31 129
LLPS-Asf-0317Aspergillus flavus27.073e-37 147
LLPS-Aso-0419Aspergillus oryzae27.074e-37 146
LLPS-Sot-0605Solanum tuberosum27.033e-1682.0
LLPS-Cus-1398Cucumis sativus26.984e-0959.7
LLPS-Spr-1449Sporisorium reilianum26.871e-24 110
LLPS-Dos-0156Dothistroma septosporum26.81e-36 146
LLPS-Zem-1578Zea mays26.678e-1683.6
LLPS-Sol-1641Solanum lycopersicum26.561e-1995.1
LLPS-Crn-0477Cryptococcus neoformans26.421e-28 120
LLPS-Phv-1552Phaseolus vulgaris26.233e-2097.1
LLPS-Mua-1782Musa acuminata26.061e-1479.7
LLPS-Lep-1851Leersia perrieri26.032e-1169.7
LLPS-Vir-0958Vigna radiata26.023e-1684.7
LLPS-Hea-1068Helianthus annuus25.435e-1890.5
LLPS-Scc-0271Schizosaccharomyces cryophilus25.374e-38 148
LLPS-Mae-0173Manihot esculenta25.17e-27 116
LLPS-Brn-1840Brassica napus25.062e-22 103
LLPS-Gor-2501Gossypium raimondii24.92e-24 108
LLPS-Brr-0914Brassica rapa24.831e-21 101
LLPS-Sem-2146Selaginella moellendorffii24.574e-1993.2
LLPS-Scj-0970Schizosaccharomyces japonicus24.564e-30 125
LLPS-Art-0307Arabidopsis thaliana24.474e-2096.7
LLPS-Miv-0485Microbotryum violaceum24.211e-24 110
LLPS-Thc-0860Theobroma cacao23.986e-23 104
LLPS-Arl-1260Arabidopsis lyrata23.852e-2097.1
LLPS-Viv-1757Vitis vinifera23.771e-23 107
LLPS-Mel-0112Melampsora laricipopulina23.734e-26 114
LLPS-Pot-0875Populus trichocarpa23.576e-25 110
LLPS-Via-0877Vigna angularis23.495e-22 102
LLPS-Glm-0999Glycine max23.471e-2097.8
LLPS-Met-0324Medicago truncatula23.111e-23 106
LLPS-Coc-0030Corchorus capsularis22.931e-1995.1
LLPS-Prp-1736Prunus persica22.812e-22 103
LLPS-Dac-0144Daucus carota22.693e-2097.1
LLPS-Php-1353Physcomitrella patens22.315e-1787.0