• Disorder▼
  • Domain▼
  • PTM▼
  • Variation▼
  • Mutation▼
  • Interaction▼
  • Disease▼
  • Drug▼
  • Physicochemical▼
  • Function▼
  • Proteomics▼
  • Structure▼
  • Localization▼
  • Expression▼
  • Element▼
  • Methylation▼

LLPS-Leo-3010

Integrated Annotations

▼ OVERVIEW

Status: Unreviewed
Protein Name: Actin-related protein 2/3 complex subunit
Ensembl Gene: ENSLOCG00000004536.1
Ensembl Protein: ENSLOCP00000005423.1
Organism: Lepisosteus oculatus
Taxa ID: 7918
LLPS Type: Others


▼ PROPERTY


——— Disorder propensity (calculated by IUPred2A)

▼ Classification

Condensates:
CondensateEvidenceOrthologs
Nucleolus, Centrosome/Spindle pole body, Stress granulePredicted from orthologs(View)

▼ FUNCTION

Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.

▼ CROSS REFERENCE

▼ SEQUENCE

Protein Sequence (FASTA)
1     MSYHSFLLEP  ISCHAWNKDR  SQIALCPNNH  DVYIYKKEGT  KWTKIHELKE  HNGQVTGIDW  60
61    APESNRIVTC  GTDRNAYVWT  LKGGVWKPTL  VILRINRAAR  CVKWSPKENK  FAVGSGSRLI  120
121   SVCYFEQEND  WWVCKHIKKP  IRSTVLSLDW  HPNNVLLAAG  SCDFKCRIFS  AYIKEVEEKP  180
181   SPTPWGSKMP  FGELMFESSS  TSGWVHSVCF  SNSGSRVAWV  SHDSCVAVAD  AGKNTAISSL  240
241   TSETLPLLTV  TFITENSLVA  AGHDCYPGLF  VYNEEKGTIT  FGGKLDVPKQ  NAQRGMTARE  300
301   RFQNLDKKAT  TETKEAILET  LHKNSISQIS  IMEGGKSKCT  KFCTTGMDGG  MTVWDVKTLE  360
361   SAMKDLKIV  369
Nucleotide CDS Sequence (FASTA)
1     ATGTCTTACC  ACAGTTTTCT  CCTGGAACCC  ATCAGCTGCC  ATGCCTGGAA  TAAAGACAGG  60
61    AGTCAAATTG  CATTATGTCC  CAACAACCAT  GATGTCTATA  TCTACAAGAA  GGAAGGAACC  120
121   AAATGGACCA  AGATCCACGA  GCTGAAGGAG  CACAATGGCC  AAGTGACAGG  CATCGACTGG  180
181   GCCCCAGAAA  GCAATCGCAT  TGTGACCTGT  GGGACTGATC  GCAATGCCTA  TGTCTGGACC  240
241   CTGAAGGGCG  GCGTGTGGAA  GCCCACTCTG  GTCATCCTGA  GGATCAACCG  AGCTGCCCGC  300
301   TGTGTCAAGT  GGTCCCCCAA  GGAAAACAAG  TTTGCTGTGG  GCAGTGGCTC  CCGGCTCATC  360
361   TCCGTCTGCT  ACTTTGAGCA  GGAAAACGAC  TGGTGGGTCT  GCAAACACAT  TAAGAAGCCC  420
421   ATTCGCTCCA  CTGTCCTGAG  CCTGGACTGG  CATCCTAACA  ATGTGCTTCT  GGCAGCTGGC  480
481   TCCTGTGACT  TCAAGTGCAG  GATCTTCTCG  GCCTACATCA  AAGAGGTGGA  GGAGAAGCCA  540
541   TCTCCAACTC  CCTGGGGTTC  CAAGATGCCT  TTCGGAGAGC  TGATGTTCGA  GTCCAGCAGC  600
601   ACATCAGGCT  GGGTGCACAG  TGTCTGCTTC  TCCAACAGTG  GCAGCCGCGT  GGCCTGGGTC  660
661   AGCCATGACA  GCTGTGTGGC  TGTAGCAGAT  GCTGGCAAAA  ACACTGCCAT  TTCCAGCCTG  720
721   ACCTCCGAGA  CCCTCCCTCT  CCTGACTGTT  ACCTTCATCA  CAGAGAACAG  CTTGGTGGCA  780
781   GCTGGACATG  ACTGCTACCC  AGGGCTCTTT  GTGTACAATG  AGGAAAAAGG  GACCATTACC  840
841   TTCGGGGGTA  AGCTGGATGT  GCCAAAGCAG  AACGCGCAGC  GTGGGATGAC  AGCAAGGGAG  900
901   CGCTTTCAGA  ACCTGGACAA  GAAAGCCACC  ACTGAGACCA  AAGAAGCCAT  CCTGGAAACC  960
961   CTGCACAAGA  ACAGCATCAG  CCAAATCTCT  ATTATGGAGG  GAGGCAAGTC  CAAATGTACA  1020
1021  AAGTTTTGTA  CCACAGGCAT  GGATGGAGGG  ATGACAGTTT  GGGATGTTAA  GACTCTGGAA  1080
1081  TCTGCGATGA  AAGATCTGAA  GATTGTTTGA  1110

▼ KEYWORD

ID
Family
Actin-binding
Complete proteome
Cytoplasm
Cytoskeleton
Reference proteome
WD repeat

▼ GENE ONTOLOGY

ID
Classification
Description
Cellular Component
Arp2/3 protein complex
Cellular Component
Cytoplasm
Molecular Function
Actin filament binding
Biological Process
Arp2/3 complex-mediated actin nucleation
Biological Process
T cell differentiation
Biological Process
Thrombocyte differentiation

▼ ORTHOLOGY

DrLLPS IDOrganismIdentityE-valueScore
LLPS-Asm-0773Astyanax mexicanus87.110.0 647
LLPS-Scf-0947Scleropages formosus86.990.0 653
LLPS-Cas-3882Carlito syrichta85.822e-163 467
LLPS-Dar-2482Danio rerio85.640.0 652
LLPS-Fia-0146Ficedula albicollis84.050.0 650
LLPS-Meg-0175Meleagris gallopavo83.420.0 650
LLPS-Gaga-0289Gallus gallus83.420.0 649
LLPS-Lac-0506Latimeria chalumnae83.20.0 640
LLPS-Ora-3081Ornithorhynchus anatinus82.070.0 640
LLPS-Otg-0986Otolemur garnettii81.40.0 637
LLPS-Orl-1667Oryzias latipes81.360.0 635
LLPS-Myl-1992Myotis lucifugus81.350.0 634
LLPS-Orn-3016Oreochromis niloticus81.320.0 633
LLPS-Urm-1546Ursus maritimus81.160.0 559
LLPS-Maf-3393Macaca fascicularis81.130.0 635
LLPS-Cea-2105Cercocebus atys81.130.0 635
LLPS-Fec-2838Felis catus80.860.0 634
LLPS-Cap-1671Cavia porcellus80.860.0 634
LLPS-Caj-1263Callithrix jacchus80.860.0 635
LLPS-Mea-1286Mesocricetus auratus80.860.0 635
LLPS-Hos-1581Homo sapiens80.590.0 633
LLPS-Pap-2621Pan paniscus80.590.0 633
LLPS-Pat-2079Pan troglodytes80.590.0 633
LLPS-Ict-0081Ictidomys tridecemlineatus80.590.0 631
LLPS-Poa-1973Pongo abelii80.590.0 636
LLPS-Gog-3278Gorilla gorilla80.590.0 632
LLPS-Sus-1979Sus scrofa80.590.0 634
LLPS-Ran-1700Rattus norvegicus80.590.0 632
LLPS-Dio-0839Dipodomys ordii80.590.0 630
LLPS-Fud-0299Fukomys damarensis80.320.0 632
LLPS-Mup-1341Mustela putorius furo80.320.0 632
LLPS-Tut-1507Tursiops truncatus80.320.0 634
LLPS-Caf-1015Canis familiaris80.050.0 628
LLPS-Paa-0276Papio anubis80.00.0 629
LLPS-Rhb-0043Rhinopithecus bieti79.680.0 624
LLPS-Man-0062Macaca nemestrina79.680.0 624
LLPS-Icp-1025Ictalurus punctatus79.670.0 581
LLPS-Xet-0696Xenopus tropicalis79.620.0 616
LLPS-Aon-1788Aotus nancymaae79.570.0 620
LLPS-Gaa-0018Gasterosteus aculeatus79.210.0 623
LLPS-Mod-0477Monodelphis domestica79.080.0 605
LLPS-Bot-0130Bos taurus79.030.0 624
LLPS-Tar-1317Takifugu rubripes78.630.0 619
LLPS-Ova-0182Ovis aries78.490.0 613
LLPS-Pof-0800Poecilia formosa78.420.0 612
LLPS-Ten-1179Tetraodon nigroviridis78.360.0 620
LLPS-Chs-0908Chlorocebus sabaeus78.170.0 607
LLPS-Loa-3188Loxodonta africana78.130.0 624
LLPS-Mum-0511Mus musculus78.130.0 626
LLPS-Xim-0609Xiphophorus maculatus77.990.0 572
LLPS-Aim-1510Ailuropoda melanoleuca77.870.0 628
LLPS-Orc-1575Oryctolagus cuniculus77.60.0 605
LLPS-Anp-2045Anas platyrhynchos73.717e-94 286
LLPS-Scm-1426Scophthalmus maximus73.670.0 545
LLPS-Mam-1468Macaca mulatta73.260.0 544
LLPS-Nol-4310Nomascus leucogenys72.510.0 559
LLPS-Eqc-2699Equus caballus72.510.0 616
LLPS-Sah-2146Sarcophilus harrisii71.470.0 553
LLPS-Pes-1033Pelodiscus sinensis71.160.0 552
LLPS-Tag-2823Taeniopygia guttata71.160.0 550
LLPS-Anc-0679Anolis carolinensis70.890.0 547
LLPS-Mal-3748Mandrillus leucophaeus70.80.0 520
LLPS-Spr-1200Sporisorium reilianum56.583e-101 313
LLPS-Cis-0769Ciona savignyi55.035e-130 385
LLPS-Cae-1715Caenorhabditis elegans53.744e-129 382
LLPS-Cii-2329Ciona intestinalis53.682e-127 378
LLPS-Drm-1624Drosophila melanogaster52.452e-138 406
LLPS-Phv-2528Phaseolus vulgaris49.572e-73 235
LLPS-Sol-0504Solanum lycopersicum47.041e-70 242
LLPS-Amt-2206Amborella trichopoda46.455e-53 184
LLPS-Brr-3002Brassica rapa46.273e-1063.5
LLPS-Tum-1563Tuber melanosporum45.051e-92 288
LLPS-Pug-0005Puccinia graminis44.769e-102 313
LLPS-Abg-0834Absidia glauca44.694e-105 321
LLPS-Zyt-0493Zymoseptoria tritici44.414e-96 298
LLPS-Asc-0587Aspergillus clavatus44.384e-97 300
LLPS-Put-1335Puccinia triticina44.369e-103 316
LLPS-Pytr-0976Pyrenophora triticirepentis44.322e-95 296
LLPS-Pyt-1261Pyrenophora teres44.322e-95 296
LLPS-Scj-1410Schizosaccharomyces japonicus44.294e-94 293
LLPS-Crn-1480Cryptococcus neoformans44.162e-105 323
LLPS-Aso-1473Aspergillus oryzae44.112e-92 288
LLPS-Ast-1398Aspergillus terreus43.969e-98 301
LLPS-Asf-1538Aspergillus flavus43.66e-87 283
LLPS-Asn-1331Aspergillus nidulans43.565e-96 297
LLPS-Asni-1565Aspergillus niger43.564e-96 298
LLPS-Usm-1163Ustilago maydis43.492e-101 313
LLPS-Nef-0952Neosartorya fischeri43.411e-96 299
LLPS-Miv-0360Microbotryum violaceum43.348e-97 301
LLPS-Fus-0415Fusarium solani43.331e-90 283
LLPS-Sem-2445Selaginella moellendorffii43.323e-89 280
LLPS-Fuo-0081Fusarium oxysporum43.254e-91 285
LLPS-Asfu-0290Aspergillus fumigatus43.137e-97 300
LLPS-Php-1030Physcomitrella patens43.134e-90 285
LLPS-Ved-0132Verticillium dahliae43.091e-92 288
LLPS-Scc-0280Schizosaccharomyces cryophilus43.051e-94 294
LLPS-Lem-0667Leptosphaeria maculans42.941e-92 289
LLPS-Sob-2167Sorghum bicolor42.864e-88 277
LLPS-Phn-1331Phaeosphaeria nodorum42.862e-91 287
LLPS-Yal-1389Yarrowia lipolytica42.821e-86 273
LLPS-Fuv-1401Fusarium verticillioides42.785e-91 285
LLPS-Scs-1040Sclerotinia sclerotiorum42.786e-90 281
LLPS-Prp-0222Prunus persica42.622e-90 283
LLPS-Pot-1876Populus trichocarpa42.512e-90 283
LLPS-Nia-0531Nicotiana attenuata42.473e-89 280
LLPS-Gor-0445Gossypium raimondii42.471e-90 284
LLPS-Brn-2199Brassica napus42.433e-92 288
LLPS-Trr-0084Trichoderma reesei42.423e-88 277
LLPS-Trv-0229Trichoderma virens42.389e-88 276
LLPS-Mel-0026Melampsora laricipopulina42.126e-95 296
LLPS-Scp-0433Schizosaccharomyces pombe42.054e-91 285
LLPS-Hea-2431Helianthus annuus42.021e-87 276
LLPS-Cogr-1658Colletotrichum graminicola41.941e-90 283
LLPS-Gag-1297Gaeumannomyces graminis41.942e-88 278
LLPS-Art-2588Arabidopsis thaliana41.937e-82 261
LLPS-Dos-1175Dothistroma septosporum41.921e-90 284
LLPS-Viv-0992Vitis vinifera41.899e-93 290
LLPS-Mao-0724Magnaporthe oryzae41.832e-89 280
LLPS-Cus-1470Cucumis sativus41.784e-86 272
LLPS-Orbr-0347Oryza brachyantha41.711e-84 268
LLPS-Vir-1099Vigna radiata41.644e-90 281
LLPS-Blg-1376Blumeria graminis41.643e-85 270
LLPS-Brd-0826Brachypodium distachyon41.536e-82 261
LLPS-Arl-0923Arabidopsis lyrata41.461e-88 278
LLPS-Dac-1064Daucus carota41.412e-84 268
LLPS-Beb-1636Beauveria bassiana41.391e-88 278
LLPS-Coo-1452Colletotrichum orbiculare41.391e-90 283
LLPS-Met-2364Medicago truncatula41.385e-93 290
LLPS-Bro-0777Brassica oleracea41.352e-91 286
LLPS-Ors-0129Oryza sativa41.211e-84 268
LLPS-Orm-1729Oryza meridionalis41.213e-83 266
LLPS-Orr-1912Oryza rufipogon41.212e-83 267
LLPS-Orni-0974Oryza nivara41.212e-83 267
LLPS-Orb-0875Oryza barthii41.212e-83 267
LLPS-Ori-0691Oryza indica41.211e-84 268
LLPS-Orgl-1846Oryza glumaepatula41.212e-83 267
LLPS-Sei-1261Setaria italica41.146e-84 266
LLPS-Cog-0983Colletotrichum gloeosporioides41.112e-88 278
LLPS-Nec-1072Neurospora crassa40.984e-92 288
LLPS-Lep-0877Leersia perrieri40.956e-83 265
LLPS-Tra-1085Triticum aestivum40.931e-80 258
LLPS-Thc-1435Theobroma cacao40.924e-87 275
LLPS-Coc-0388Corchorus capsularis40.717e-86 271
LLPS-Hov-1473Hordeum vulgare40.512e-73 239
LLPS-Glm-1553Glycine max40.482e-90 283
LLPS-Mae-2583Manihot esculenta40.436e-85 269
LLPS-Kop-0341Komagataella pastoris40.323e-82 262
LLPS-Via-2132Vigna angularis40.256e-72 238
LLPS-Mua-0378Musa acuminata39.781e-84 268
LLPS-Zem-1804Zea mays39.596e-84 267
LLPS-Tru-0675Triticum urartu38.727e-70 230
LLPS-Asg-0143Ashbya gossypii37.879e-71 232
LLPS-Sac-1174Saccharomyces cerevisiae36.152e-66 221
LLPS-Chr-1120Chlamydomonas reinhardtii35.422e-38 147
LLPS-Orp-2305Oryza punctata32.69e-50 178
LLPS-Sot-2050Solanum tuberosum24.64e-0755.8